市場調查報告書
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1410090
2023年至2028年鷹架技術市場預測Scaffold Technology Market - Forecasts from 2023 to 2028 |
全球支架技術市場預計在預測期內複合年成長率為 13.57%。
支架技術特別應用於組織工程、再生醫學和藥物研發。在組織工程領域,支架是3D結構,為細胞發育提供機械支撐和合適的環境。它代表了組織再生和修復的潛在解決方案。這些支架由多種材料製成,模仿天然存在的細胞外基質,並為細胞附著和生長提供表面。支架技術用於藥物開發,產生分子框架,可以對其進行修改以測試各種化合物,從而加快發現新藥的過程。
支架技術市場的主要成長動力是對生物和轉化研究中使用的 3D 細胞模型的需求不斷成長。由於藥物開發過程中的困難,支架技術市場隨著 3D 細胞培養的興起而不斷擴大。病毒學和流行病學研究、試管內模型系統的建構以及尋找有效的抗感染療法都在大量利用組織工程來推動支架技術市場的成長。
支架常用於 3D 細胞培養。支架是多孔的,允許氧氣、營養物質和廢物的移動。因此,細胞在黏合到支架之前能夠在支架網周圍增殖和遷移。成熟細胞在相互作用的同時生長,最終轉變為與原始組織相連的結構。因此,支架在3D細胞培養中的廣泛應用預計將推動支架技術市場的成長。
支架的技術突破激發了再生醫學和組織工程的革命性進步。 3D 列印和生物列印的結合改變了支架的創建,可以精確控制細胞和結構的放置。這些進步是支架技術市場的關鍵成長動力。溶劑澆鑄、溶液噴射紡絲、顆粒浸出、自組裝、氣體發泡、纖維網、光刻等是鷹架技術涉及的一些製程。
幾種 FDA 批准的生物相容性聚合物已被開發出來,用於製造各種用於治療癌症復發的3D立體支架,這一直是支架技術市場成長的主要驅動力。分析了聚合物選擇的各種品質,包括腫瘤微環境、轉移、化療和免疫療法藥物類型、高表面積、高孔隙率和可調的機械性能。此外,3D支架在癌症免疫治療中越來越受到關注,進一步加速了支架技術市場的成長。
由於奈米纖維支架在組織工程和再生應用中的使用不斷增加,其用途正在擴大。例如,世界各地的科學家正在專注於使用奈米纖維支架來創建神經組織。用作細胞外基質的奈米結構是使用靜電紡絲等技術創建的。靜電紡絲具有易於使用、價格實惠和高度彈性等多種優點,可加速支架技術市場的成長。
由於政府的各種舉措,支架技術市場預計將成長。例如,2023年6月,印度藥品監管總局批准了由哺乳動物器官製成的組織工程支架,這是一種D級生物醫學設備,可以快速、經濟地治療皮膚病變,且疤痕最小。這在我的家鄉是第一次允許。科學技術部 (DST) 和 Sree Chila Trinal 醫學科技研究所合作滿足建立中央藥品標準控制組織的所有法律要求。
北美支架技術市場預計將穩定成長。這是由於對幹細胞和再生醫學的研究增加、擴大這些技術應用的資金增加以及醫療保健系統的建立所推動的。研究人員還改進了 3D 微支架技術,以重新編程神經幹細胞並支持神經元之間的連接。這些網路沒有注射單一細胞,而是在小鼠中顯示出更高的大腦存活率。此外,幹細胞生物學家和生醫材料專家最近在國家醫療圖像和生物工程研究所的支持下合作進行了一項研究。
許多公司正在創建用於組織再生的新型 3D 生物列印客製化支架。例如,3D Systems與聯合治療公司於2022年6月共同開發了尖端的3D列印器官技術。此外,奈米纖維支架因其高表面積與體積比以及模仿天然細胞外基質纖維結構的能力而受到歡迎。此外,2022 年 11 月,Gelomics 和 Rousselot 宣佈建立聯合品牌合作夥伴關係,使用 Gelomics 的 LunaGel 3D 組織培養系統和 Rousselot Biomedical 的 X-Pure GelMA(甲基丙烯醯明膠)細胞外基質。
2023 年 6 月,美國衛生研究院 (NIH) 向 RevBio, Inc. 授予 200 萬美元津貼,用於開發創新的牙科黏合骨支架產品。 2023年4月,Systemic Bio在美國德克薩斯州建立了一個新實驗室,用於製造水凝膠支架並進行晶載技術的研發,以改善藥物研發發現和開發。 2022年8月,Conmed宣布收購生物感應支架供應商Biorez,以擴大其用於運動醫學的軟組織癒合產品組合。
The global scaffold technology market is estimated to grow at a CAGR of 13.57% during the forecast period.
Scaffold technology is used especially in tissue engineering, regenerative medicine, and drug discovery. Scaffolds are three-dimensional constructs that give mechanical support and a favourable environment for cell development in the field of tissue engineering. They present potential solutions for tissue regeneration and repair. Made of a variety of materials, these scaffolds imitate the extracellular matrix found in nature, providing a surface on which cells may cling and multiply. Scaffold technology is used in drug development to generate molecular frameworks that may be altered to produce a variety of compounds for testing, which expedites the process of finding new drugs.
Major growth drivers for the scaffold technology market are the increased need for 3D cellular models for use in biological research and translational studies. The scaffold technology market is expanding as the 3D cell culture is rising due to difficulties in the drug development process. The study of virology and epidemiology, the creation of in vitro model systems, and the search for effective anti-infective therapies all make substantial use of tissue engineering which fuels the scaffold technology market growth.
For 3D cell culture, scaffolds are significantly used. Scaffolds enable the movement of oxygen, nutrients, and waste because of their porosity. Cells can therefore multiply and move around the scaffold web before adhering to it. The maturing cells interact with one another as they grow and eventually transform into structures that are connected to the tissues from which they originally came. This growing application of scaffolding in 3D cell culture is expected to fuel the scaffold technology market growth.
Technological breakthroughs in scaffolding have influenced revolutionary advances in regenerative medicine and tissue engineering. The creation of scaffolds has been transformed by the combination of 3D printing with bioprinting, which allows for exact control over the arrangement of cells and structure. These advancements are major growth drivers for the scaffold technology market. Solvent casting, solution blow spinning, particle leaching, self-assembly, gas foaming, fiber mesh, and lithography are some of the processes included in scaffold technology.
Several biocompatible polymers that have received FDA approval have been established to create a variety of 3D scaffolds to treat cancer recurrence, which is a major driver for the scaffold technology market growth. For choosing a polymer, the type of tumour microenvironment, metastasis, chemo medicines, and immunotherapeutics are analyzed for various qualities such as high surface volume, high porosity, and tuneable mechanical properties. Moreover, 3D scaffolds are of interest for cancer immunotherapy and are further upsurging the scaffold technology market growth.
The use of nano-fiber scaffolds is expanding due to their growing use in tissue engineering and regeneration applications. For instance, scientists around the globe are focusing on research related to nanofiber scaffold usage in the creation of nerve tissue. Nano-sized structures that can serve as an extracellular matrix for cellular transformation are made using techniques like electrospinning. Electrospinning provides several benefits such as simplicity of use, affordability, and high flexibility, which can accelerate the scaffold technology market growth.
The scaffold technology market is anticipated to grow due to various government initiatives. For instance, in June 2023, the Indian Drugs Controller gave their permission to the first locally created tissue engineering scaffold made from mammalian organs, a Class D biomedical device that may quickly and affordably treat skin lesions with little scarring. The Department of Science and Technology (DST) and Sree Chira Triunal Institute for Medical Sciences and Technology, collaborated to meet all the legal requirements to form the Central Drugs Standard Control Organization.
The scaffold technology market is predicted to grow at a steady pace in North America. This can be attributed to a rise in research on stem cells and regenerative medicine, increased funding for expanding the applications of these technologies, and a well-established healthcare system. Furthermore, researchers have also improved 3D micro scaffold technology, which helps reprogrammed neural stem cells and supports connections between neurons. Instead of injecting individual cells, these networks exhibited greater brain survival in mice. Additionally, stem cell biologists and biomaterial specialists collaborated in their recent work supported by the National Institute of Biomedical Imaging and Bioengineering.
For tissue regeneration, many businesses are creating novel 3D bio-printed customized scaffolds. For instance, 3D Systems and United Therapeutics Corporation collaborated to create cutting-edge 3D-printed organ technology in June 2022. Moreover, nanofiber scaffolds are gaining popularity because of their high surface area-to-volume ratio and capacity to replicate the fibrous structure of the extracellular matrix in nature. Additionally, in November 2022, Gelomics and Rousselot announced a cobranding partnership that used Gelomics' LunaGel 3D Tissue Culture System and Rousselot Biomedical's X-Pure GelMA (gelatin methacryloyl) extracellular matrix.