市場調查報告書
商品編碼
1466293
重組蛋白市場:按產品、服務、最終用戶、功能分類 - 全球預測 2024-2030Recombinant Proteins Market by Product (Adhesion Molecules & Receptors, Growth Factors & Chemokines, Immune Response Proteins), Services (Cloning, Expression, Purification), End-User, Function - Global Forecast 2024-2030 |
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預計2023年重組蛋白市場規模為50.5億美元,預計2024年將達58億美元,2030年將達130.4億美元,複合年成長率為14.51%。
重組蛋白是透過將修飾的基因插入細菌、酵母或哺乳動物細胞等表現系統中來產生的,以產生具有高純度和功能性的所需蛋白。 Recombinant Proteins 從事源自重組 DNA 技術的基因工程蛋白質的研究、開發、製造和商業化。由於感染疾病和慢性病的流行、新療法和診斷方法的醫療支出增加以及生物製藥公司研發投資的增加,對高品質重組蛋白的需求不斷增加。基因組學技術的快速進步以及生技藥品相對於小分子藥物的日益採用正在推動重組蛋白的採用不斷增加。然而,高昂的生產和維護成本可能會對最終用途產業使用重組 DNA 產生負面影響。此外,動物育種和飼料效率的新應用以及重組蛋白開發的大量投資預計將推動全球最終用途部門使用這些蛋白質。
主要市場統計 | |
---|---|
基準年[2023] | 50.5億美元 |
預測年份 [2024] | 58億美元 |
預測年份 [2030] | 130.4億美元 |
複合年成長率(%) | 14.51% |
黏附分子和受體在產品研究中的重要用途
黏附分子和受體對於細胞間通訊、遷移和免疫反應調節至關重要。這些被廣泛用於了解癌症、發炎和感染疾病的研究。生長因子和趨化素控制細胞生長、分化和遷移過程。這些對於創傷治療、組織修復和幹細胞研究的應用至關重要。免疫反應蛋白是控制感染防禦機制和發炎控制的免疫系統的重要組成部分。研究人員使用免疫反應蛋白來研究自體免疫疾病和疫苗開發。激酶蛋白在控制細胞分裂、生存、代謝和其他生物過程的細胞內訊號傳導途徑中至關重要。激酶蛋白作為癌症治療和慢性發炎治療的藥物標靶具有重要的潛力。膜蛋白在細胞訊號傳導、運輸和黏附中很重要,並參與許多生理過程,這導致它們在藥物發現和開發中的應用。重組代謝酶在調節細胞代謝和能量產生的生物途徑中至關重要。這些用於針對糖尿病和肥胖症等代謝疾病的藥物發現。調節蛋白控制基因表現和細胞過程,例如細胞凋亡和細胞週期進程。這些蛋白質廣泛用於癌症治療和其他涉及不受控制的細胞增殖和分化的疾病。結構蛋白為細胞和組織提供機械支撐,同時保持生物體內的結構完整性。它應用於組織工程和再生醫學相關的生物醫學研究。
服務 表達服務注重高產量和與目標蛋白質特性的兼容性。
重組蛋白的克隆涉及將目標基因插入適當的表達載體,產生指導宿主細胞中蛋白質生產的重組DNA分子。基於需求的克隆服務偏好包括高效率、特異性和對不同生物的適應性。表達是指將遺傳訊息轉化為功能性蛋白質產物的過程。有幾個因素會影響表現系統的選擇,包括生產力水平、與轉譯後修飾(PTM) 的兼容性以及下游應用所需的更高產量和純度水平的放大難度。精製對於去除表達蛋白中的污染物以用於藥物發現、診斷和研究等下游應用至關重要。對精製服務的需求包括高選擇性、重現性、產量和最小的樣品損失。隨著分子生物學技術的進步使得同時創建多個克隆成為可能,對克隆服務的需求不斷增加。表達服務透過宿主系統的改進而不斷發展,以適應不同複雜程度的多種蛋白質。隨著樹脂化學和設備的進步,精製服務不斷進步,從而實現更高的產量和產量。
最終用戶:重組蛋白在製藥和生物製藥公司的廣泛使用
學術研究機構是重組蛋白技術創新和高級研究的基礎。這些實驗室需要高品質、可靠且具成本效益的重組蛋白來進行結構生物學、功能研究、藥物發現和診斷研究。受託製造廠商(CMO)和合約研發組織(CRO)為專門從事重組蛋白生產、分析開發和臨床前測試的生物製藥公司提供研發和產品開發外包服務。這些公司強調快速交付、有競爭力的價格和可客製化的服務,以滿足客戶的需求。生物製藥公司需要高品質、符合 GMP 的重組蛋白來開發治療和診斷方法。這些最終用戶群體優先考慮品質、可靠性和經濟高效的解決方案。此外,CRO 和 CMO 優先考慮滿足截止日期和多樣化客戶的客製化產品,而製藥和生物製藥公司則需要嚴格的監管合規性和強大的製造能力。
功能:重組蛋白在藥物發現和藥物開發的潛在需求
重組蛋白對於診斷至關重要,有助於各種疾病的檢測和監測。酵素結合免疫吸附檢測法(ELISA)或側流免疫檢測是一種常見的診斷技術,利用重組蛋白作為抗原或抗體來檢測與特定疾病相關的特定生物標記。重組蛋白在生技藥品、疫苗、細胞和基因療法的藥物發現和製造中發揮重要作用,並作為潛在的治療標靶和候選藥物。此外,它還有助於進行高通量篩檢測定,以識別針對特定疾病途徑的先導化合物。診斷應用主要關注靈敏度、特異性、快速性和成本效益。相較之下,藥物發現和開發強調重組蛋白的純度、穩定性、擴充性和功能活性。
區域洞察
由於美洲擁有成熟的製藥和生物技術公司,擁有先進的研究設施和確保高品質產品的法規,重組蛋白市場正在不斷發展。此外,技術的進步、研發 (R&D) 資金的大幅增加、慢性病盛行率的上升以及對個人化藥物的需求不斷成長正在推動美洲對重組蛋白的需求。歐洲、中東和非洲地區是重組蛋白市場的新興市場,因為對這些蛋白的使用有嚴格的規定,而且製造商必須遵守 GMP 標準。由於慢性病的流行、細胞生物學、生物化學、結構和生物物理研究活動的增加以及對高效生物製藥的需求,亞太地區的重組蛋白市場正在不斷成長。此外,生物製藥公司和學術機構之間的技術進步和合作正在加速將實驗室創新轉化為商業性可行的產品,並且預計將促進世界各地最終用途部門對重組蛋白的採用。
FPNV定位矩陣
FPNV定位矩陣對於評估重組蛋白市場至關重要。我們檢視與業務策略和產品滿意度相關的關鍵指標,以對供應商進行全面評估。這種深入的分析使用戶能夠根據自己的要求做出明智的決策。根據評估,供應商被分為四個成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市場佔有率分析
市場佔有率分析是一種綜合工具,可以對重組蛋白市場供應商的現狀進行深入而深入的研究。全面比較和分析供應商在整體收益、基本客群和其他關鍵指標方面的貢獻,以便更好地了解公司的績效及其在爭奪市場佔有率時面臨的挑戰。此外,該分析還提供了對該行業競爭特徵的寶貴見解,包括在研究基準年觀察到的累積、分散主導地位和合併特徵等因素。詳細程度的提高使供應商能夠做出更明智的決策並制定有效的策略,以獲得市場競爭優勢。
1. 市場滲透率:提供有關主要企業所服務的市場的全面資訊。
2. 市場開拓:我們深入研究利潤豐厚的新興市場,並分析其在成熟細分市場的滲透率。
3. 市場多元化:提供有關新產品發布、開拓地區、最新發展和投資的詳細資訊。
4. 競爭評估和情報:對主要企業的市場佔有率、策略、產品、認證、監管狀況、專利狀況和製造能力進行全面評估。
5. 產品開發與創新:提供對未來技術、研發活動和突破性產品開發的見解。
1、重組蛋白市場規模及預測如何?
2.重組蛋白市場預測期內需要考慮投資的產品、細分市場、應用和領域有哪些?
3. 重組蛋白市場的技術趨勢和法規結構是什麼?
4.重組蛋白市場主要廠商的市場佔有率為何?
5. 進入重組蛋白市場的合適型態和策略性手段是什麼?
[187 Pages Report] The Recombinant Proteins Market size was estimated at USD 5.05 billion in 2023 and expected to reach USD 5.80 billion in 2024, at a CAGR 14.51% to reach USD 13.04 billion by 2030.
The recombinant proteins are created by inserting a modified gene into an expression system such as bacteria, yeast, or mammalian cells, which then produce the desired protein with high purity and functionality. Recombinant proteins involve research, development, manufacturing, and commercialization of genetically engineered proteins derived from recombinant DNA technology. The prevalence of infectious and chronic diseases, increasing healthcare expenditure needed for new therapeutics and diagnostics, and increased R&D investments within biopharmaceutical companies are raising the need for high-quality recombinant proteins. The rapid advancements in genomics technologies and growing adoption of biologics over small-molecule drugs are resulting in increased adoption of recombinant proteins. However, the high cost of production and maintenance may adversely impact the use of recombinant DNA by the end-use industries. In addition, the emerging applications in animal reproduction and to enhance feed efficiency and significant investments in recombinant protein development are the factors expected to encourage the use of these proteins by the end-use sectors worldwide.
KEY MARKET STATISTICS | |
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Base Year [2023] | USD 5.05 billion |
Estimated Year [2024] | USD 5.80 billion |
Forecast Year [2030] | USD 13.04 billion |
CAGR (%) | 14.51% |
Product: Significant use of adhesion molecules & receptors for research purposes
Adhesion molecules and receptors are essential for cell-cell communication, migration, and immune response regulation. They are widely used in research to understand cancer, inflammation, and infection. Growth factors and chemokines regulate cellular growth, differentiation, and migration processes. They are vital for wound healing, tissue repair, and stem cell research applications. Immune response proteins are crucial components of the immune system that regulate infection defense mechanisms and inflammation control. Researchers use the immune response proteins to study autoimmune diseases and vaccine development. Kinase proteins are essential in cellular signal transduction pathways regulating cell division, survival, metabolism, and other biological processes. Kinase proteins possess significant potential as drug targets for cancer treatment and management of chronic inflammatory conditions. Membrane proteins are crucial for cell signaling, transport, and adhesion and have applications in drug discovery and development due to their involvement in numerous physiological processes. Recombinant metabolic enzymes are vital in biological pathways regulating cellular metabolism and energy production. They are used in drug discovery efforts targeting metabolic diseases, such as diabetes or obesity. Regulatory proteins control gene expression or cellular processes such as apoptosis and cell cycle progression. They are extensively used for cancer treatment and other diseases involving uncontrolled cell growth or differentiation. Structural proteins provide mechanical support to cells and tissues while maintaining structural integrity within organisms. They find applications in biomedical research related to tissue engineering or regenerative medicine.
Services: Expression services focus on high yields and compatibility with target protein characteristics
Recombinant protein cloning involves the insertion of a target gene into an appropriate expression vector, resulting in a recombinant DNA molecule that directs protein production in host cells. Need-based preferences for cloning services include high efficiency, specificity, and adaptability to different organisms. Expression refers to the process of translating a gene's information into a functional protein product. Several factors influence the choice of an expression system, such as productivity levels, compatibility with post-translational modifications (PTMs), and ease of scale-up for higher yields or purity levels required for downstream applications. Purification is essential to remove contaminants from the expressed protein and prepare it for downstream applications such as drug discovery, diagnostics, and research. Preferences for purification services include high selectivity, reproducibility, yield, and minimal sample loss. The demand for cloning services has increased due to advancements in molecular biology techniques, enabling the generation of multiple clones simultaneously. Expression services have evolved with improvements in host systems to accommodate diverse proteins with varying complexity levels. Purification services continue progressing with resin chemistry and instrumentation advances, allowing higher throughput and yields.
End-User: Extensive utilization of recombinant proteins in pharmaceutical and biopharmaceutical companies
Academic research institutes are the foundation for innovative and advanced research in recombinant protein technology. These institutes require high-quality, reliable, cost-effective recombinant proteins to study structural biology, functional studies, drug discovery, and diagnostics. Contract manufacturing organizations (CMOs) and contract research organizations (CROs) provide outsourced research and product development services to biopharmaceutical companies specializing in recombinant protein production, assay development, and preclinical testing. They value rapid turnaround times, competitive pricing structures, and customizable offerings tailored to their customer needs. Pharmaceutical biopharmaceutical companies require high-quality, GMP-compliant recombinant proteins for therapeutic and diagnostic product development. These end-user segments prioritize quality, reliability, and cost-effective solutions. Academic research institutes emphasize discovery-driven research application support; biotechnology companies value customization and scalability; CROs and CMOs prioritize turnaround time and customized offerings catering to diverse customers, while pharmaceutical and biopharmaceutical companies require robust manufacturing capabilities with strict regulatory compliance.
Function: Potential demand of recombinant proteins for drug discovery & development
Recombinant proteins are essential in diagnostics, facilitating detection and monitoring of various diseases. Enzyme-linked immunosorbent assays (ELISAs) and lateral flow immunoassays are common diagnostic techniques that utilize recombinant proteins as antigens or antibodies to detect specific biomarkers associated with specific diseases. Recombinant proteins play an indispensable role in drug discovery and production of biologics, vaccines, and cell and gene therapies and serve as potential therapeutic targets or drug candidates themselves. Additionally, they facilitate high throughput screening assays to identify lead compounds targeting specific disease pathways. Diagnostic applications primarily focus on sensitivity, specificity, rapidness, and cost-effectiveness. In contrast, drug discovery & development emphasizes recombinant proteins' purity, stability, scalability, and functional activity.
Regional Insights
The recombinant protein market is evolving in the Americas owing to the presence of well-established pharmaceutical and biotech companies with advanced research facilities and regulations that ensure high-quality products. Additionally, technological advancements, significant increases in funding for research and development (R&D), the rising prevalence of chronic conditions, and a surge in demand for personalized medicines are resulting in an increased need for recombinant protein in the Americas. The EMEA region represents a developing landscape for the recombinant proteins market owing to the stringent regulations implemented to use these proteins and the requirement for manufacturers to adhere to GMP standards. The recombinant proteins market is growing in the APAC region due to the prevalence of chronic diseases, increased research activities in cell biology, biochemistry, structural and biophysical studies, and the need for efficient biopharmaceuticals. Moreover, technological advancements and collaborations between biopharmaceutical companies and academic institutions are expected to increase the translation of laboratory innovations into commercially viable products and boost the adoption of recombinant proteins by the end-use sectors across the globe.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the Recombinant Proteins Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Recombinant Proteins Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the Recombinant Proteins Market, highlighting leading vendors and their innovative profiles. These include Abcam PLC, Abnova Corporation, Agilent Technologies, Inc., Bhat Bio-tech India Private Limited, Bio-Rad Laboratories, Inc., Biogen Inc., BioLegend, Inc. by PerkinElmer, Inc., Biologics International Corp, BPS Bioscience, Inc., Bristol-Myers Squibb Company, Creative BioMart Inc., Croyez Bioscience Co., Ltd., Eli Lilly and Company, Enzo Life Sciences, Inc., Fortis Life Sciences LLC, GenScript Biotech Corporation, GeoVax Labs, Inc., Hzymes Biotech, Johnson & Johnson Services, Inc., Laurus Labs Limited, LenioBio GmbH, Lonza Group AG, Marin Biologic Laboratories, Inc., Merck KGaA, Meridian Bioscience, Inc. by SD Biosensor Inc., Miltenyi Biotec B.V. & Co. KG, Novartis AG, ProMab Biotechnologies, Inc., Proteintech Group, Inc., Proteos, Inc., R&D Systems, Inc. by Bio-Techne Corporation, Sanofi S.A., Sartorius AG, Selvita S.A., Sino Biological, Inc., SK bioscience, Takara Bio Inc., Takeda Pharmaceutical Company Limited, and Thermo Fisher Scientific, Inc..
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the Recombinant Proteins Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Recombinant Proteins Market?
3. What are the technology trends and regulatory frameworks in the Recombinant Proteins Market?
4. What is the market share of the leading vendors in the Recombinant Proteins Market?
5. Which modes and strategic moves are suitable for entering the Recombinant Proteins Market?