市場調查報告書
商品編碼
1466231
氧化壓力測定市場:按產品和服務、測試類型、技術、最終用戶、適應症分類 - 2024-2030 年全球預測Oxidative Stress Assay Market by Product & Service (Consumables, Instruments, Services), Test Type (Antioxidant Capacity Assays, Enzyme-Based Assays, Indirect Assays), Technology, End-user, Indication - Global Forecast 2024-2030 |
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氧化壓力檢測市場規模預計2023年為10.6億美元,預計2024年將達到11.7億美元,2030年將達到21.9億美元,複合年成長率為10.85%。
氧化壓力測定是一種評估體內活性氧(ROS)產生和抗氧化防禦機制之間平衡的生物分析方法。這些測定對於了解氧化壓力在細胞過程、疾病進展和治療效果中的作用至關重要。氧化壓力測定對於了解氧化壓力是神經退化性疾病、心血管疾病、癌症和老化過程等病理學的重要貢獻者。對氧化壓力測定的需求顯著增加,因為活性氧透過細胞代謝活動不斷產生並與細胞成分相互作用,損害蛋白質、核酸和脂質,導致細胞功能障礙和細胞死亡。此外,與氧化壓力相關的慢性疾病的盛行率不斷增加,增加了對能夠早期檢測和治療指導的強大診斷工具的需求。然而,先進診斷技術的高成本以及各種檢測平台缺乏標準化通訊協定導致結果不一致,極大地阻礙了氧化壓力檢測的採用。此外,對體外診斷和就地檢驗技術的需求不斷成長,為擴大氧化壓力測定在臨床環境中的應用提供了巨大的潛力。開發與先進檢測系統整合的攜帶式、易於使用的可攜式可以簡化早期診斷並實現更快的治療性介入。這些檢測平台與機器學習演算法和人工智慧 (AI) 相結合,可以幫助提高對複雜疾病機制的理解並確定新的治療標靶。
主要市場統計 | |
---|---|
基準年[2023] | 10.6億美元 |
預測年份 [2024] | 11.7億美元 |
預測年份 [2030] | 21.9億美元 |
複合年成長率(%) | 10.85% |
產品和服務最終用途領域對消耗品的需求不斷成長
氧化壓力測定耗材包括試劑、套件、酵素、探針以及檢測和測量氧化壓力標記物所需的其他材料。學術研究機構和臨床實驗室需要高品質的氧化壓力測定耗材,這些耗材既要經濟高效,又要提供準確的結果。用於氧化壓力測定的儀器包括微孔盤、光強度、螢光、光強度、流式細胞儀和高內涵篩檢系統,可靈敏地檢測氧化壓力生物標記。氧化壓力測定服務涉及將您的研究計劃外包給提供測定開發、驗證、樣品測試、資料分析和解釋服務的受託研究機構(CRO) 或核心設施。研究人員更喜歡熟悉氧化壓力測定並擁有成功計劃記錄的服務供應商,以確保結果可靠。
測試類型抗氧化能力測量的需求不斷成長
抗氧化能力測定評估檢體清除自由基和其他活性物質的整體能力,從而了解整體抗氧化能力。評估各種抗氧化劑(包括親水性和親油性化合物)的能力是這些測定的基於必要性的偏好。基於酵素的測定可測量特定氧化酵素的活性,這些酵素在維持細胞氧化還原平衡中發揮重要作用。當研究人員旨在研究特定酶途徑或確定各種干預措施對酶活性的影響時,這些測定是首選。間接測定透過測量氧化過程中產生的副產物來評估氧化壓力,當由於濃度低或擔心與目標分子的反應性而難以直接檢測時,間接測定非常有用。基於活性氧的測定旨在直接檢測特定的活性氧分子。研究人員更喜歡用這種方法來測量各種實驗條件下單一活性氧的水平。
酵素結合免疫吸附檢測法(ELISA) 技術的日益普及
層析法是一種廣泛使用的分離技術,用於定量和鑑定內源性或外源性添加的活性氧標記物,例如脂肪過氧化產物、麩胺基硫和其他抗氧化劑。酵素結合免疫吸附檢測法(ELISA)是一種基於酵素的測試,使用特異性抗體來測量生物檢體中的氧化壓力生物標記物,具有高靈敏度和選擇性。 ELISA 方法的主要優點是其簡單、處理時間快以及適合高通量篩檢。流式細胞技術是一種強大的多參數技術,用於使用與活性氧和其他細胞標記物反應的螢光染料測量單細胞水平的氧化壓力。該技術能夠對 ROS 水平、粒線體電位和細胞活力等多個參數進行高通量即時分析。高內涵篩檢(HCS) 是一種基於成像的先進方法,它將螢光顯微鏡與自動影像擷取和分析相結合,以監測活細胞中的氧化壓力。利用這項技術,研究人員可以同時評估多個終點,例如活性氧的產生、抗氧化反應和細胞型態的變化,從而獲得更高水平的資訊。無標定檢測技術,例如表面等離子共振 (SPR)、生物層干涉測量 (BLI) 和電化學方法,提供了非侵入性替代方法來量化不需要螢光標記的氧化壓力生物標記。這些技術可以即時監測分子間相互作用,並且可以直接研究自然狀態下的功能活動。共聚焦顯微鏡、電子顯微鏡和原子力顯微鏡等顯微技術用於可視化細胞內 ROS 的產生和定位。
氧化壓力測定在最終用戶製藥和生物技術公司中的普及
氧化壓力測定主要用於學術研究機構研究活性氧在癌症、神經退化性疾病和心血管疾病等各種疾病中的功能。臨床實驗室對於診斷和個人化醫療至關重要,需要進行氧化壓力測定來評估患者的抗氧化狀態,評估藥物的有效性,並監測與氧化壓力相關的疾病的治療結果。委外研發機構(CRO) 為製藥和生技公司提供研究外包服務,同時在不影響品質標準的情況下保持成本效率。在 CRO 進行的臨床前研究中,氧化壓力測定透過監測藥物開發過程中可能導致細胞損傷的活性氧水平,在評估藥物安全性和有效性方面發揮重要作用。製藥和生物技術公司正在大力投資研發,以發現針對氧化壓力相關疾病的創新療法。
擴大氧化壓力檢測法在呼吸系統疾病適應症檢測的應用
氧化壓力會影響癌症的發生和進展,因為它會誘發 DNA 損傷並導致基因突變。癌症研究需要檢測活性氧 (ROS)、評估抗氧化能力以及評估麩胺基硫和丙二醛等特定生物標記。在心血管疾病 (CVD) 中,氧化還原穩態失衡會導致內皮功能障礙、發炎和斑塊形成。在 CVD 研究中,測量一氧化氮 (NO) 的產生和脂肪過氧化對於更好地了解潛在的疾病機制至關重要。糖尿病的慢性高血糖會增加氧化壓力,導致組織損傷和併發症,如神經病變、腎臟病變和視網膜病變。氧化壓力也與氣喘、特發性肺纖維化(IPF)和慢性阻塞性肺病(COPD)等疾病有關。該領域的關鍵優先領域包括測量支氣管上皮細胞中ROS產生的測定以及檢測與氧化性肺損傷相關的生物標記的測定。
區域洞察
在美洲地區,人們對活性氧 (ROS) 的認知不斷提高,慢性病盛行率不斷上升,以及對先進氧化壓力檢測方法開發的投資增加,正在推動氧化壓力檢測方法的採用。各個學術機構正在廣泛研究疾病進展和老化中的氧化壓力。 Thermo Fisher Scientific, Inc. 和 Merck KGaA 等製造商正專注於合作研究活動,以擴大其質譜產品組合併鞏固其在氧化壓力測定市場的地位。在亞太地區(APAC),由於印度和中國等新興國家的經濟開拓,氧化壓力檢測市場正在快速成長。由於強大的研發投資以及 Abnova Corporation 和FUJIFILM Wako Pure Chemical 等主要製造商的存在,中國和日本已成為氧化壓力測定市場的主要參與者。由於製藥和生物技術公司的強大存在以及政府對研究計劃的資助,歐洲氧化壓力測定市場在歐洲、中東和非洲地區得到了顯著發展。由於慢性病的增加和人口老化,歐盟(EU)國家正在積極投資氧化壓力檢測的開發。歐盟成員國之間的監管協調實現了產品核可和創新支援的簡化方法。由於醫療基礎設施的改善,中東正在經歷顯著成長,而非洲則越來越關注非傳染性疾病,為未來的市場擴張提供了機會。
FPNV定位矩陣
FPNV定位矩陣對於評估氧化壓力檢測市場至關重要。我們檢視與業務策略和產品滿意度相關的關鍵指標,以對供應商進行全面評估。這種深入的分析使用戶能夠根據自己的要求做出明智的決策。根據評估,供應商被分為四個成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市場佔有率分析
市場佔有率分析是一種綜合工具,可以對氧化壓力測定市場中供應商的現狀進行深入而詳細的研究。全面比較和分析供應商在整體收益、基本客群和其他關鍵指標方面的貢獻,以便更好地了解公司的績效及其在爭奪市場佔有率時面臨的挑戰。此外,該分析還提供了對該行業競爭特徵的寶貴見解,包括在研究基準年觀察到的累積、分散主導地位和合併特徵等因素。這種詳細程度的提高使供應商能夠做出更明智的決策並制定有效的策略,從而在市場上獲得競爭優勢。
1. 市場滲透率:提供有關主要企業所服務的市場的全面資訊。
2. 市場開拓:我們深入研究利潤豐厚的新興市場,並分析其在成熟細分市場的滲透率。
3. 市場多元化:提供有關新產品發布、開拓地區、最新發展和投資的詳細資訊。
4. 競爭評估和情報:對主要企業的市場佔有率、策略、產品、認證、監管狀況、專利狀況和製造能力進行全面評估。
5. 產品開發與創新:提供對未來技術、研發活動和突破性產品開發的見解。
1.氧化壓力檢測市場的市場規模與預測是多少?
2.在氧化壓力檢測市場的預測期內,有哪些產品、細分市場、應用和領域需要考慮投資?
3.氧化壓力檢測市場的技術趨勢和法規結構是什麼?
4.氧化壓力檢測市場主要供應商的市場佔有率是多少?
5. 進入氧化壓力檢測市場的合適型態和策略手段是什麼?
[183 Pages Report] The Oxidative Stress Assay Market size was estimated at USD 1.06 billion in 2023 and expected to reach USD 1.17 billion in 2024, at a CAGR 10.85% to reach USD 2.19 billion by 2030.
The oxidative stress assay is a bioanalytical method to evaluate the balance between reactive oxygen species (ROS) production and the antioxidant defense mechanisms within biological systems. These assays are essential for understanding oxidative stress's role in cellular processes, disease progression, and treatment efficacy. Oxidative stress assay is crucial in understanding oxidative stress, a significant contributor to pathological conditions such as neurodegenerative diseases, cardiovascular disorders, cancer, and aging processes. The constant generation of ROS through cellular metabolic activities and their interaction with cellular components cause harm to proteins, nucleic acids, and lipids, leading to cell dysfunction or cell death, significantly increasing the need for oxidative stress assays. Moreover, the rising prevalence of chronic diseases associated with oxidative stress has increased the demand for robust diagnostic tools that enable early detection and treatment guidance. However, high costs associated with advanced diagnostic technologies and the lack of standardized protocols across various assay platforms result in inconsistent results, significantly impeding the adoption of oxidative stress assays. In addition, the growing demand for in vitro diagnostics and point-of-care testing technologies presents a vast potential for expanding the application of oxidative stress assays in clinical settings. Developing portable, easy-to-use devices integrated with advanced detection systems can streamline early diagnosis and enable faster therapeutic interventions. Combining machine learning algorithms and artificial intelligence (AI) into these assay platforms facilitates a greater understanding of complex disease mechanisms and helps identify novel therapeutic targets.
KEY MARKET STATISTICS | |
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Base Year [2023] | USD 1.06 billion |
Estimated Year [2024] | USD 1.17 billion |
Forecast Year [2030] | USD 2.19 billion |
CAGR (%) | 10.85% |
Product & Service: Rising demand for consumables across end-use sectors
Consumables for oxidative stress assays include reagents, kits, enzymes, probes, and other materials required to detect and measure oxidative stress markers. Academic research institutes and clinical laboratories require high-quality consumables for oxidative stress assays that cost-effectively produce accurate results. Instruments used in oxidative stress assays include microplate readers, spectrophotometers, fluorometers, luminometers, flow cytometers, and high-content screening systems that sensitively detect oxidative stress biomarkers. Oxidative stress assay services involve outsourcing research projects to contract research organizations (CROs) or core facilities offering assay development, validation, sample testing, data analysis, and interpretation services. Researchers prefer service providers with expertise in oxidative stress assays and a proven track record of successful projects to ensure reliable results.
Test Type: Increasing demand for antioxidant capacity assays
Antioxidant capacity assays evaluate the overall capacity of a specimen to scavenge free radicals and other reactive species, providing an understanding of the total antioxidant potential. The need-based preference for these assays lies in their ability to evaluate various antioxidants, including hydrophilic and lipophilic compounds. Enzyme-based assays measure the activity of specific antioxidant enzymes that play crucial functions in maintaining cellular redox balance. These assays are preferred when researchers aim to investigate particular enzymatic pathways or determine the effect of various interventions on enzyme activity. Indirect assays are employed to evaluate oxidative stress by measuring by-products generated during oxidation processes, which are helpful when direct detection is difficult due to low concentration or reactivity concerns with target molecules. Reactive oxygen species-based assays are designed to detect specific ROS molecules directly. The researchers prefer them to determine the levels of individual ROS species under various experimental conditions.
Technology: Emerging popularity of Enzyme-linked Immunosorbent Assay (ELISA)
Chromatography is a widespread separation technique used that quantifies and identifies endogenous or exogenously added ROS markers such as lipid peroxidation products, glutathione, and other antioxidants. Enzyme-linked immunosorbent assay (ELISA) is an enzyme-based test that utilizes specific antibodies to measure oxidative stress biomarkers in biological samples with high sensitivity and selectivity. The significant advantage of ELISA is its simplicity, fast processing time, and adaptability to high-throughput screening. Flow cytometry is a powerful multi-parameter technique used to measure oxidative stress at the single-cell level using fluorescent dyes that react with ROS or other cellular markers. This technology offers high-throughput and real-time analysis of multiple parameters such as ROS levels, mitochondrial potential, and cell viability. High-content screening (HCS) is an advanced imaging-based method that combines fluorescence microscopy with automated image acquisition and analysis to monitor oxidative stress in living cells. Researchers can assess multiple endpoints simultaneously with this technology, such as ROS production, antioxidant responses, and cell morphology changes, contributing to higher content information. Label-free detection technologies, including surface plasmon resonance (SPR), bio-layer interferometry (BLI), or electrochemical methods, offer non-invasive alternatives to quantify oxidative stress biomarkers without the need for fluorescent labels. These techniques provide real-time monitoring of molecular interactions and allow for studying functional activity directly in their natural state. Microscopy techniques such as confocal, electron, or atomic force microscopy are used to visualize intracellular ROS production and localization.
End-user: Penetration of oxidative-stress-assay in pharmaceutical and biotechnology companies
Academic research institutes primarily use oxidative stress assays to investigate the function of reactive oxygen species (ROS) in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Clinical laboratories are essential in diagnostics and personalized medicine, which require oxidative stress assays to evaluate patients' antioxidant status, assess drug efficacy, or monitor treatment outcomes for conditions associated with oxidative stress. Contract research organizations (CROs) provide research outsourcing services to pharmaceutical and biotech companies while maintaining cost efficiency without compromising quality standards. Oxidative stress assays play an important role in preclinical studies conducted by CROs to assess drug safety and efficacy by monitoring ROS levels with the potential to cause cellular damage during drug development. Pharmaceutical and biotechnology companies heavily invest in research and development to discover innovative therapeutics targeting oxidative stress-related diseases.
Indication: Expanding use of oxidative-stress-assay for detecting respiratory diseases
Oxidative stress is consequential in cancer development and progression, as it can induce DNA damage, leading to genetic mutations. Need-based preferences for cancer research include detecting reactive oxygen species (ROS), assessing antioxidant capacity, and evaluating specific biomarkers, including glutathione or malondialdehyde. In cardiovascular diseases (CVDs), imbalanced redox homeostasis contributes to endothelial dysfunction, inflammation, and plaque formation. Assays measuring nitric oxide (NO) production or lipid peroxidation are essential for CVD research to understand the underlying disease mechanisms better. Chronic hyperglycemia in diabetes increases oxidative stress, causing tissue damage and complications such as neuropathy, nephropathy, and retinopathy. Oxidative stress is implicated in conditions such as asthma, idiopathic pulmonary fibrosis (IPF), and chronic obstructive pulmonary disease (COPD). Key preference areas in this field include assays for measuring ROS production in bronchial epithelial cells or detecting biomarkers related to oxidative lung injury.
Regional Insights
In the Americas region, increased awareness and research on reactive oxygen species (ROS), the rising prevalence of chronic diseases, and growing investments in developing advanced oxidative stress assays have raised the adoption of oxidative stress assays in the region. Various academic institutions have extensively studied oxidative stress in disease progression and aging. The presence of manufacturers such as Thermo Fisher Scientific, Inc. and Merck KGaA focus on collaboration activities to expand its mass spectrometry portfolio, thereby strengthening its position in the oxidative stress assay market. The Asia-Pacific (APAC) region witnessed rapid oxidative stress assay market growth due to expansive economic development across emerging nations such as India and China. China and Japan have established themselves as key players in the oxidative stress assay market with strong R&D investments and the presence of key manufacturers such as Abnova Corporation and Fujifilm Wako Pure Chemical Corporation. Europe's oxidative stress assay market significantly developed in the EMEA region due to its strong presence of pharmaceutical and biotechnology companies and government funding for research projects. The European Union (EU) countries actively invest in oxidative stress assay development due to the rising incidences of chronic disorders and an aging population. Regulatory harmonization across EU member states has enabled a streamlined approach towards product approvals and innovation support. The Middle East is witnessing significant growth due to improving healthcare infrastructure, while Africa's emerging focus on non-communicable diseases presents opportunities for future market expansion.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the Oxidative Stress Assay Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Oxidative Stress Assay Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the Oxidative Stress Assay Market, highlighting leading vendors and their innovative profiles. These include Abcam PLC, Agilent Technologies, Inc., AMS Biotechnology, Arbor Assays Inc., Assay Genie, Bio-Rad Laboratories, Inc., Bio-Techne Corporation, BioAssay Systems, Biomedica Medizinprodukte GmbH, BPS Bioscience, Inc., Callegari Srl, Cayman Chemical Company, Cell Biolabs, Inc., Cytek Biosciences, Inc., Eagle Biosciences, Inc., Enzo Biochem, Inc., Ethos Biosciences, Inc., Geno Technology Inc., Genox Corporation, Helvetica Health Care Sarl, Hycult Biotech Inc., Kamiya Biomedical Company, Labstat Inc., Merck KGaA, Oxford Biomedical Research, Inc., Promega Corporation, Qiagen N.V., Thermo Fisher Scientific, Inc., Vivid Microscopy, LLC, and ZenBio, Inc..
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the Oxidative Stress Assay Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Oxidative Stress Assay Market?
3. What are the technology trends and regulatory frameworks in the Oxidative Stress Assay Market?
4. What is the market share of the leading vendors in the Oxidative Stress Assay Market?
5. Which modes and strategic moves are suitable for entering the Oxidative Stress Assay Market?