市場調查報告書
商品編碼
1470809
小鼠模型市場:按類型、技術、治療領域、應用分類 - 2024-2030 年全球預測Mice Model Market by Type (Conditioned/Surgically Modified Mice, Genetically Engineered Mice, Hybrid/Congenic Mice), Technology (CRISPR/CAS9, Embryonic Stem Cell Injection, Microinjection), Therapeutic Area, Application - Global Forecast 2024-2030 |
※ 本網頁內容可能與最新版本有所差異。詳細情況請與我們聯繫。
預計2023年滑鼠模型市場規模為14.9億美元,2024年達到16.1億美元,預計2030年將達到26.1億美元,複合年成長率為8.34%。
小鼠模型是科學家和研究人員用於生物醫學研究以及與基因工程、藥物發現和治療測試相關的研究的實驗室小鼠(小家鼠)。由於人類和小鼠在遺傳、生物學和行為上相似,因此這些模型對於模擬人類疾病過程至關重要。小鼠模型使科學界能夠了解疾病機制,評估藥物的有效性,並在人體測試之前探索潛在的治療方法。對個人化醫療的需求不斷成長,各種遺傳疾病的盛行率不斷增加,以及包括癌症、心血管和神經系統疾病在內的生物醫學研究的激增,正在推動小鼠模型的使用增加。此外,越來越多的藥物監管核准需要廣泛的臨床前測試,進一步推動了對小鼠模型的需求。儘管顯著成長,小鼠模型市場仍然受到與動物實驗相關的倫理問題、創建和維護基因工程小鼠模型的高成本以及在小鼠中複製人類疾病的複雜性的限制,面臨一些挑戰。然而,CRISPR/Cas9基因編輯技術的持續發展為創建更準確和多樣化的疾病模型提供了新途徑。此外,全球公共和私營部門對生物醫學研究和開發的投資增加也極大地推動了市場的發展。
主要市場統計 | |
---|---|
基準年[2023] | 14.9億美元 |
預測年份 [2024] | 16.1億美元 |
預測年份 [2030] | 26.1億美元 |
複合年成長率(%) | 8.34% |
基因轉殖小鼠對於評估類型基因治療的結果越來越重要
經過調理或手術改造的小鼠透過手術干預進行專門改造,以創建代表小鼠基因組中不自然存在的人類狀況的模型。這些修改包括移除特定器官、引入腫瘤或創建損傷模型。這種方法使研究人員能夠在嚴格模仿他們想要重現的人類生理條件的受控環境中研究疾病機制、開發外科技術並評估治療藥物。基因工程小鼠(GEM)是透過操縱遺傳物質而產生的。基因敲除、基因敲入和基因轉殖等技術用於引入、移除或修飾小鼠基因組內的特定基因。這類小鼠模型對於研究基因功能、疾病的遺傳基礎、基因改造的潛在影響非常重要。混合/同類小鼠是透過受管制育種策略產生的,將來自兩個或多個品系的遺傳物質組合起來以獲得特定的遺傳背景。混合小鼠透過雜交兩種不同的近交系,提供雜合性和廣泛的遺傳多樣性,有助於整體健康和繁殖性能。另一方面,同源小鼠是透過將混合小鼠與原始近交系之一回交多代而產生的,從而可以分離特定的遺傳性狀或基因座。近親交配小鼠是兄弟姊妹或親代與後代之間至少 20 代交配的結果,產生了遺傳同質的品系。這些小鼠具有一致的遺傳背景,這最大限度地減少了實驗研究中的變異性,使它們在研究中具有無價的價值。近交系小鼠廣泛用於遺傳學、免疫學和疾病模型研究,也被用作開發基因工程模型和藥理毒理學研究的平台。近交小鼠是一個基因多樣化的群體,有意保持雜合性。這種遺傳多樣性反映了人類群體內的遺傳多樣性,對於毒理學、藥理學和安全性評估研究特別有用。
擴大採用應用小鼠模型,可以在臨床試驗之前研究治療效果和安全性
小鼠模型在藥物發現和藥物開發中的應用對於製藥業至關重要。人類和小鼠在生理和遺傳上相似,這使得它們對於評估新藥物化合物的功效和安全性具有無價的價值。透過利用小鼠模型,研究人員可以闡明潛在治療藥物的藥物動力學和動態特性,並確定有前途的候選藥物以進行進一步開發。此外,這些模型可以幫助在進入人體臨床試驗之前了解新藥的作用機制、劑量反應關係和潛在毒性,從而最大限度地降低後期開發階段失敗的風險。小鼠模型對於個人化醫療的進步至關重要。基因工程小鼠和患者來源的異質骨移植(PDX)使研究人員能夠高精度地模擬人類遺傳狀況和疾病。這使得根據基因組成研究個體對治療藥物的反應成為可能,從而製定更精確、更有效的治療策略。個人化小鼠模型有助於識別疾病診斷的生物標記、預測治療結果和評估標靶治療。除了在藥物開發和個人化醫療中發揮重要作用外,小鼠模型還廣泛用於各種生物醫學研究應用。其中包括研究遺傳學、闡明疾病機制、測試免疫反應以及評估環境因素對健康的影響。小鼠模型在增進我們對癌症、心血管疾病、糖尿病和神經系統疾病等複雜疾病的認知方面發揮著至關重要的作用。其多功能性和適應性也使其適用於再生醫學研究和老化研究,為生物醫學知識的擴展和新治療方法的尋找做出了重大貢獻。
區域洞察
由於研究機構和製藥公司的持續研究活動,美洲的關鍵字市場正在顯著成長。此外,聯邦對藥物和疫苗開發的津貼和投資正在擴大該地區的小鼠模型市場。然而,歐洲國家遺傳性疾病和神經系統併發症的增加增加了小鼠模型的使用來了解與老齡化相關的疾病。此外,新興的臨床研究機構和有利的政府措施正在支持歐洲、中東和非洲地區的市場開拓。對個人化治療的需求不斷成長、老年疾病的擴散、免疫疾病病例的增加以及感染疾病患者病率的增加,正在推動美洲和歐洲地區採用小鼠模型。另一方面,由於研究活動和政府臨床活動舉措的增加,預計亞太地區的小鼠模型市場在預測期內將顯著成長。亞太地區的人口成長和慢性病的流行凸顯了廣泛研究的必要性,並鼓勵採用小鼠模型。
FPNV定位矩陣
FPNV定位矩陣對於評估老鼠模型市場至關重要。我們檢視與業務策略和產品滿意度相關的關鍵指標,以對供應商進行全面評估。這種深入的分析使用戶能夠根據自己的要求做出明智的決策。根據評估,供應商被分為四個成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市場佔有率分析
市場佔有率分析是一種綜合工具,可以對滑鼠模型市場供應商的現狀進行深入而詳細的研究。全面比較和分析供應商在整體收益、基本客群和其他關鍵指標方面的貢獻,以便更好地了解公司的績效及其在爭奪市場佔有率時面臨的挑戰。此外,該分析還提供了對該行業競爭特徵的寶貴見解,包括在研究基準年觀察到的累積、分散主導地位和合併特徵等因素。詳細程度的提高使供應商能夠做出更明智的決策並制定有效的策略,以獲得市場競爭優勢。
1. 市場滲透率:提供有關主要企業所服務的市場的全面資訊。
2. 市場開拓:我們深入研究利潤豐厚的新興市場,並分析其在成熟細分市場的滲透率。
3. 市場多元化:提供有關新產品發布、開拓地區、最新發展和投資的詳細資訊。
4.競爭評估與資訊:對主要企業的市場佔有率、策略、產品、認證、監管狀況、專利狀況、製造能力等進行全面評估。
5. 產品開發與創新:提供對未來技術、研發活動和突破性產品開發的見解。
1. 滑鼠模型市場的市場規模與預測是多少?
2.在滑鼠模型市場預測期內,有哪些產品、細分市場、應用和領域需要考慮投資?
3. 滑鼠模型市場的技術趨勢和法規結構是什麼?
4.滑鼠模型市場主要廠商的市場佔有率是多少?
5.進入滑鼠模型市場合適的型態和策略手段是什麼?
[187 Pages Report] The Mice Model Market size was estimated at USD 1.49 billion in 2023 and expected to reach USD 1.61 billion in 2024, at a CAGR 8.34% to reach USD 2.61 billion by 2030.
Mice models are laboratory mice (Mus musculus) used by scientists and researchers for biomedical research and studies related to genetic engineering, drug discovery, and therapeutic testing. These models are pivotal in mimicking human disease processes due to the genetic, biological, and behavioral similarities between humans and mice. Mice models enable the scientific community to understand disease mechanisms, assess drug efficacy, and explore potential treatments before they are tested in humans. The increasing demand for personalized medicine, the growing prevalence of various genetic disorders, and a surge in biomedical research involving cancer, cardiovascular diseases, and neurological disorders enhanced the usage of mice models. The rise in regulatory approvals for pharmaceutical drugs also necessitates extensive preclinical studies, further propelling the demand for mice models. Despite the significant growth, the mice model market faces several challenges, such as ethical concerns related to animal testing, the high cost of creating and maintaining genetically engineered mice models, and the complexity of reproducing human diseases in mice. However, the continual development of CRISPR/Cas9 gene-editing technology presents novel avenues for creating more accurate and diverse disease models. Additionally, the increasing investment in biomedical research and development by both public and private sectors worldwide offers a significant boost to the market.
KEY MARKET STATISTICS | |
---|---|
Base Year [2023] | USD 1.49 billion |
Estimated Year [2024] | USD 1.61 billion |
Forecast Year [2030] | USD 2.61 billion |
CAGR (%) | 8.34% |
Type: Growing significance of genetically engineered mice for evaluating gene therapy outcomes
Conditioned or surgically modified mice are specifically altered through surgical interventions to create models that represent human conditions not naturally occurring in the mouse genome. These modifications can include the removal of specific organs, the introduction of tumors, or the creation of injury models. This methodology allows for the study of disease mechanisms, the development of surgical techniques, and the evaluation of therapeutics in a controlled environment, closely mimicking the human physiological conditions they aim to replicate. Genetically engineered mice (GEM) are created by manipulating their genetic material. Techniques such as gene knockout, gene knock-in, and transgenesis are employed to introduce, remove, or alter specific genes within the mouse genome. This category of mice models is important for studying gene function, the genetic basis of diseases, and the potential effects of genetic modifications. Hybrid/congenic mice are produced through controlled breeding strategies to combine genetic material from two or more strains to achieve specific genetic backgrounds. Hybrid mice result from mating two different inbred strains, offering heterozygosity and broader genetic diversity, which is beneficial for general health and reproductive performance. Congenic mice, on the other hand, are created by backcrossing hybrids to one of the original inbred strains for multiple generations, allowing for the isolation of specific genetic traits or loci. Inbred mice are derived from at least 20 generations of brother-sister or parent-offspring mating, which results in a genetically uniform strain. These mice are invaluable in research owing to their consistent genetic background, which minimizes variability in experimental studies. Inbred strains are used extensively in the study of genetics, immunology, and disease models, including as platforms for developing genetically engineered models and for pharmacological and toxicological studies. Outbred mice are genetically diverse populations that are kept deliberately heterozygous. This genetic variability mirrors the genetic diversity within human populations, making them particularly useful for toxicology, pharmacology, and safety assessment studies.
Application: Rising adoption of mice models to explore therapeutic efficacy and safety profiles before clinical trials
The applications of mice models in drug discovery and development are essential for the pharmaceutical industry. The physiological and genetic similarities between humans and mice make them invaluable for assessing the efficacy and safety of new pharmaceutical compounds. By utilizing mice models, researchers can elucidate the pharmacokinetic and pharmacodynamic properties of potential therapeutic agents, enabling the identification of promising drug candidates for further development. Moreover, these models help in understanding the mechanism of action, dose-response relationship, and potential toxicity of new drugs before entering human clinical trials, thereby minimizing the risk of failure at later development stages. Mice models are pivotal in the advancement of personalized medicine. Using genetically engineered mice and patient-derived xenografts (PDX), researchers can mimic human genetic conditions and diseases at a high level of accuracy. This enables the study of individual responses to therapeutics based on genetic makeup, leading to more precise and effective treatment strategies. Personalized mice models are instrumental in identifying biomarkers for disease diagnosis, predicting therapeutic outcomes, and evaluating targeted therapies. Besides their significant role in drug development and personalized medicine, mice models are extensively used in various biomedical research applications. These include studying genetics, understanding disease mechanisms, testing immunological responses, and evaluating the impact of environmental factors on health. Mice models have been crucial in advancing our knowledge of complex diseases such as cancer, cardiovascular diseases, diabetes, and neurological disorders. Their versatility and adaptability also make them suitable for regenerative medicine studies and aging research, contributing profoundly to expanding biomedical knowledge and exploring new therapeutic avenues.
Regional Insights
The mice model market is growing significantly in the Americas owing to continuous research activities by research organizations and pharmaceutical companies. Moreover, federal government support in terms of grants and investment for drug development and vaccine development has enhanced the scope of the mice model in the region. However, the rising genetic disease and neurological complications in European countries have increased the utilization of mouse models to understand age-related diseases. In addition, emerging clinical research institutes and favorable government initiatives drive market development in the EMEA region. The rising need for personalized medications, surging geriatric disease, increasing cases of immune disease, and growing prevalence of infectious disease boost the adoption of mice models across the Americas and Europe regions. On the other hand, the Asia-Pacific region witnesses significant growth prospects of the mice models market in the forecast period owing to growing research activities and government initiatives for clinical activities. APAC's increasing population and prevalence of chronic diseases underscore the need for extensive research, thereby propelling the adoption of mice models.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the Mice Model Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Mice Model Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the Mice Model Market, highlighting leading vendors and their innovative profiles. These include Applied StemCell, Inc., Aragen Life Sciences Ltd., Biocytogen Boston Corporation, Charles River Laboratories International, Inc., CompareNetworks, Inc., Creative Biolabs., Crown Bioscience by JSR Life Sciences, LLC, Cyagen US Inc. by PolyGene AG, Envigo by Inotiv, Inc., GenOway, Harbour BioMed, Horizon Discovery Ltd. by PerkinElmer, Inc., inGenious Targeting Laboratory, Inc., ITR Laboratories Canada, Janvier Labs, Marshall BioResources, MD Biosciences, Mirimus, Inc., Oncodesign, SA, Ozgene Pty Ltd., PhoenixBio Co., Ltd., Shanghai Model Organisms Center, Inc., Taconic Biosciences, Inc., The Jackson Laboratory, TransCure bioServices, Translational Drug Development, LLC, Transnetyx, Inc., Urosphere SAS, Vivo Bio Tech Ltd., and XenOPAT SL by Bellvitge Biomedical Research Institute.
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the Mice Model Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Mice Model Market?
3. What are the technology trends and regulatory frameworks in the Mice Model Market?
4. What is the market share of the leading vendors in the Mice Model Market?
5. Which modes and strategic moves are suitable for entering the Mice Model Market?