市場調查報告書
商品編碼
1422819
2024-2032 年聚乙二醇化蛋白質市場報告(按產品、蛋白質類型、應用、最終用戶和地區)PEGylated Proteins Market Report by Product, Protein Type, Application, End User, and Region 2024-2032 |
2023年全球聚乙二醇化蛋白市場規模達13億美元。展望未來, IMARC Group預計到2032年市場規模將達到28億美元,2024-2032年複合年成長率(CAGR)為8.87%。慢性病盛行率的增加、癌症治療中產品的廣泛使用以及聚乙二醇化蛋白產品批准數量的不斷增加是推動市場發展的一些關鍵因素。
聚乙二醇化蛋白質是透過與聚乙二醇 (PEG) 共價結合進行修飾的生物分子。它涉及聚乙二醇化技術,透過改變生物分子的物理和化學特性(例如其構象、靜電結合和疏水性)來改善藥物的藥物動力學行為。聚乙二醇化蛋白廣泛用於治療應用,例如疫苗、荷爾蒙替代療法、遺傳性疾病、貧血和凝血障礙。它也用於治療多種疾病的藥物,包括腎臟病、多發性硬化症、血友病和癌症。聚乙二醇化蛋白質有助於延長半衰期,增加穩定性、溶解度和蛋白水解保護,減少腎臟排泄、免疫原性和毒性,並增強藥物傳遞的功效。除此之外,聚乙二醇化蛋白質無毒性、水溶性、親水性、非抗原性和非免疫原性。
全球腎臟疾病、自體免疫疾病、遺傳性疾病、肝炎和類風濕性關節炎等慢性病盛行率的上升是推動市場成長的關鍵因素之一。聚乙二醇化蛋白廣泛用於治療發炎、向細胞傳遞校正基因、預防血栓、傳遞生長激素、預防慢性腎臟病的進展。與此一致的是,在癌症治療中廣泛使用產品將化療藥物直接輸送到癌細胞並減少對健康細胞的副作用,有利於市場成長。除此之外,聚乙二醇化技術的各種改進,例如開發可以生產更小和更複雜分子的新聚乙二醇化方法,正在為市場成長提供動力。此外,廣泛採用聚乙二醇化來提高集落刺激因子 (CSF) 的穩定性和半衰期,使它們作為治療劑更有效,這也是另一種生長誘導因子。此外,與非蛋白質藥物相比,蛋白質藥物的採用率不斷上升,其中聚乙二醇化增加了蛋白質的循環和半衰期,提高了其效率,正在推動市場成長。其他因素,包括聚乙二醇化蛋白產品批准數量的增加、生物技術和分子生物學工程領域的發展、聚乙二醇分子在生物製藥中的整合及其相關優勢、老年人口的增加以及各種政府舉措的實施製藥業的監管標準預計將推動市場進一步成長。
The global PEGylated proteins market size reached US$ 1.3 Billion in 2023. Looking forward, IMARC Group expects the market to reach US$ 2.8 Billion by 2032, exhibiting a growth rate (CAGR) of 8.87% during 2024-2032. The increasing prevalence of chronic diseases, the widespread product utilization in cancer treatment, and the escalating number of product approvals for PEGylated proteins represent some of the key factors driving the market.
PEGylated proteins are biomolecules that have been modified by covalent conjugation with polyethylene glycol (PEG). It involves the PEGylation technique that improves the pharmacokinetic behavior of the medicine by altering the biological molecule's physical and chemical characteristics, such as its conformation, electrostatic binding, and hydrophobicity. PEGylated proteins are widely used in therapeutic applications, such as vaccines, hormone replacement therapy, genetic disorders, anemia, and blood clotting disorder. It is also used in various drugs for diseases, including kidney disease, multiple sclerosis, hemophilia, and cancers. PEGylated proteins help in the extension of half-life, increasing stability, solubility, and proteolytic protection, reducing renal excretion, immunogenicity, and toxicity, and enhancing the efficacy of drug delivery. Besides this, PEGylated proteins are non-toxic, water-soluble, hydrophilic, non-antigenic, and non-immunogenic.
The rising prevalence of chronic diseases, such as kidney ailments, autoimmune diseases, genetic disorders, hepatitis, and rheumatoid arthritis across the globe is one of the key factors driving the market growth. PEGylated proteins are widely used to treat inflammation, deliver corrective genes to cells, prevent blood clots, deliver growth hormones, and prevent the progression of chronic kidney disease. In line with this, the widespread product utilization in cancer treatment to deliver chemotherapy drugs directly to cancer cells and reduce the side effects on healthy cells is favoring the market growth. Apart from this, various improvements in the PEGylation technology, such as the development of new PEGylation methods that can produce smaller and more complex molecules, are providing an impetus to the market growth. Additionally, the widespread adoption of PEGylation to improve the stability and half-life of colony-stimulating factors (CSFs), making them more effective as therapeutic agents, is acting as another growth-inducing factor. Furthermore, the rising adoption of protein-based drugs over non-protein-based drugs wherein PEGylation increases the circulation and half-life of the proteins, improving its efficiency, is propelling the market growth. Other factors, including the increasing number of product approvals for PEGylated proteins, development in the field of biotechnology and molecular biology engineering, the integration of PEG molecules in biopharmaceuticals and the associated advantages, rising geriatric population, and the implementation of various government initiatives to increase regulatory standards in the pharmaceutical industry, are anticipated drive the market further toward growth.
IMARC Group provides an analysis of the key trends in each segment of the global PEGylated proteins market, along with forecasts at the global, regional, and country level from 2024-2032. Our report has categorized the market based on product, protein type, application, and end user.
Consumables
PEGylation Reagents
PEGylation Kits
Services
A detailed breakup and analysis of the PEGylated proteins market based on the product has also been provided in the report. This includes consumables (PEgylation reagents and PEgylation kits) and services. According to the report, consumables accounted for the largest market share.
Colony Stimulating Factors
Interferons
Erythropoietin
mAbs
Recombinant Factor VII
Others
The report has provided a detailed breakup and analysis of the PEGylated proteins market based on the protein type. This includes colony stimulating factors, interferons, erythropoietin, mAbs, recombinant factor VII and others. According to the report, colony stimulating factors represented the largest segment.
Cancer Treatment
Hepatitis
Chronic Kidney Diseases
Hemophilia
Multiple Sclerosis
Gastrointestinal Disorders
Others
A detailed breakup and analysis of the PEGylated proteins market based on the application has also been provided in the report. This includes cancer treatment, hepatitis, chronic kidney diseases, hemophilia, multiple sclerosis, gastrointestinal disorders, and others. According to the report, cancer treatment represented the largest segment.
Pharmaceutical and Biotechnology Companies
Contract Research Organizations
Academic and Research Institutes
The report has provided a detailed breakup and analysis of the PEGylated proteins market based on the end user. This includes pharmaceutical and biotechnology companies, contract research organizations, and academic and research institutes. According to the report, pharmaceutical and biotechnology companies represented the largest segment.
North America
United States
Canada
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Asia Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
The report has also provided a comprehensive analysis of all the major regional markets that include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America was the largest market for PEGylated proteins. Some of the factors driving the North America PEGylated proteins market included the rising geriatric population, increasing prevalence of chronic diseases, and extensive research and development (R&D).
The report has also provided a comprehensive analysis of the competitive landscape in the global PEGylated proteins market. Detailed profiles of all major companies have also been provided. Some of the companies covered include Abcam plc, Biomatrik Inc., Creative PEGWorks, Iris Biotech GmbH, JenKem Technology USA Inc., Laysan Bio Inc., NOF America Corporation (NOF Corporation), Profacgen, Thermo Fisher Scientific Inc., etc.