市場調查報告書
商品編碼
1378953
2023-2028 年按作用機制、藥物類別、活性譜、給藥途徑、最終用戶和地區分類的抗生素市場報告Antibiotics Market Report by Action Mechanism, Drug Class, Spectrum of Activity, Route of Administration, End User, and Region 2023-2028 |
2022年全球抗生素市場規模達到494億美元。展望未來, IMARC Group預計到2028年市場規模將達到626億美元,2022-2028年複合年成長率(CAGR)為4.0%。肺炎、結核病和其他傳染病在個體中的盛行率不斷上升,抗菌素抗藥性(AMR)的發生率不斷上升,以及生物技術和藥物發現技術的進步是推動市場的一些主要因素。
抗生素是一類用於治療細菌感染的藥物。它們以多種形式廣泛存在,例如丸劑、膠囊、注射劑、乳膏和軟膏。它們可以殺死細菌或抑制其生長,以有效消除感染。它們針對細菌細胞內的特定機製或結構,干擾其重要功能並阻止其繁殖。除此之外,它們還有助於增強個體的免疫系統。因此,抗生素被用來治療各種疾病,例如泌尿道感染(UTI)、呼吸道感染、皮膚感染和某些個別性傳染病。
目前,世界各地群眾中多種慢性病的盛行率不斷上升,推動了市場的成長。此外,抗生素透過全球線上和實體門市的廣泛供應正在加強市場的成長。除此之外,對局部抗生素的需求不斷成長,因為它們可以最大限度地降低個人手術部位感染的風險,並且正在對市場產生積極影響。此外,為了保障動物健康和福利以及支持食品安全,畜牧業中擴大使用抗生素,這也促進了市場的成長。與此一致的是,老年人口對抗生素的需求不斷成長正在支持市場的成長。此外,消費者對預防保健措施的認知不斷增強正在推動市場的成長。
傳染病病率上升
全球範圍內,肺炎、結核、泌尿道感染(UTI)、胃腸道感染和敗血症等傳染病的盛行率呈上升趨勢。由於衛生設施不足,導致細菌感染傳播,人們擴大遭受這些疾病的困擾。此外,抗藥性細菌的出現也增加了對抗生素的需求。對有助於治療這些感染的有效抗生素的需求不斷增加。抗生素是專門針對和消除細菌感染而設計的。它們能有效殺死體內的細菌並促進個體癒合。此外,抗生素是在醫療保健專業人員的指導下使用的,以最佳化患者的治療效果。
抗菌素抗藥性 (AMR) 的發生率增加
全球抗生素抗藥性(AMR)的發生率不斷上升,推動了抗生素市場的發展。當細菌、病毒、寄生蟲或真菌進化並對治療它們的藥物產生抗藥性時,就會發生抗菌素抗藥性。它降低了抗生素的有效性,導致感染時間更長、更嚴重、醫療費用增加以及個人死亡率高。抗生素的過度使用和濫用會導致抗藥性細菌的產生,從而降低傳統抗生素的效果。此外,多重抗藥性菌株,如抗甲氧西林金黃色葡萄球菌(MRSA)和抗碳青黴烯類腸桿菌(CRE)也更為常見。這就需要開發新的抗生素或替代療法來對抗這些抗藥性菌株。
抗生素技術進步
生物技術、分子生物學和藥物發現技術的創新有助於提高抗生素開發的效率和有效性。基因組學和高通量篩選可以識別潛在的藥物標靶並篩選大型化合物庫。此外,電腦輔助藥物設計可以預測藥物療效並最佳化候選抗生素。這些技術進步簡化了抗生素的發現過程,並減少了與傳統方法相關的時間和成本。此外,診斷技術的進步,例如快速病原體識別和藥物敏感性測試,有助於適當的抗生素選擇和處方,從而改善患者的治療效果。此外,技術進步有助於開發新的、更有效的抗生素來解決傳染病和抗菌素抗藥性。
IMARC Group提供了全球抗生素市場報告各細分市場主要趨勢的分析,以及 2023 年至 2028 年全球、區域和國家層面的預測。我們的報告根據作用機制、藥物類別、活性範圍、給藥途徑和最終用戶對市場進行了分類。
細胞壁合成抑制劑
蛋白質合成抑制劑
DNA合成抑制劑
RNA合成抑制劑
分枝菌酸抑制劑
其他
細胞壁合成抑制劑代表最大的細分市場
報告根據行動機制對市場進行了詳細的細分和分析。這包括細胞壁合成抑制劑、蛋白質合成抑制劑、DNA合成抑制劑、RNA合成抑制劑、黴菌酸抑制劑等。根據該報告,細胞壁合成是最大的部分。
細胞壁合成是一類針對細菌細胞壁的抗生素。這些抗生素會干擾細胞壁的合成過程,導致細胞壁損傷並最終導致細菌死亡。此外,青黴素、頭孢菌素和碳青黴烯類是一些細胞壁合成抑制劑。它們透過抑制青黴素結合蛋白(PBP)的酶發揮作用,這些酶參與肽聚醣鏈的交聯。此外,細胞壁合成抑制劑對革蘭氏陽性細菌特別有效,因為它們的肽聚醣層較厚,這提供了更大的破壞目標。
頭孢菌素
青黴素
氟喹諾酮類
大環內酯
碳青黴烯類
氨基糖苷類
其他
青黴素佔大部分市場佔有率
該報告根據藥物類別提供了詳細的市場細分和分析。這包括頭孢菌素、青黴素、氟喹諾酮、大環內酯、碳青黴烯、氨基糖苷等。根據該報告,青黴素佔了最大的佔有率。
青黴素是一類廣泛使用的抗生素,屬於 BETA-內醯胺類藥物。它的作用是抑制細菌細胞壁的合成,導致細胞壁損傷和細菌死亡。它被認為是基本藥物,並作為學名藥廣泛使用。除此之外,它還廣泛應用於各種醫療保健場所,例如醫院、診所和門診場所。此外,青黴素的使用不斷增加,因為它可以有效對抗各種細菌感染,也促進了市場的成長。
廣效抗生素
窄譜抗生素
廣譜抗生素佔最大市場佔有率
該報告根據活動範圍對市場進行了詳細的細分和分析。這包括廣譜抗生素和窄譜抗生素。根據該報告,廣譜抗生素佔了最大的佔有率。
廣譜抗生素是一類對多種細菌(例如革蘭氏陽性菌和革蘭氏陰性菌)具有活性的抗生素。與此一致的是,與窄譜抗生素相比,廣譜抗生素的使用越來越多,因為它們可以有效對抗更廣泛的微生物,從而推動了市場的成長。除此之外,當致病細菌未知或感染涉及多種細菌時,廣譜抗生素有助於治療感染。適當使用廣效抗生素可以最大限度地降低體內感染的風險。
口服
注射用
專題
其他
注射劑佔據細分市場的主導地位
該報告根據給藥途徑對市場進行了詳細的細分和分析。這包括口服、腸胃外、局部用藥等。根據該報告,注射劑佔最大部分。
腸外抗生素經由消化道以外的途徑給藥,例如靜脈注射(IV)、肌肉(IM)或皮下(SC)途徑。這些途徑可將藥物繞過胃腸系統直接輸送到血液或深層組織。此外,腸外抗生素可提供快速且可預測的藥物吸收和即時的治療效果。它們也適合胃腸功能受損的患者。除此之外,它還可以實現準確的劑量,並且在需要高藥物濃度或無法口服給藥的情況下特別有益。
醫院
專科診所
其他
醫院佔最大市場佔有率
該報告提供了基於最終用戶的詳細市場細分和分析。這包括醫院、專賣店等。報告稱,醫院佔最大部分。
由於居住在醫療機構的患者數量不斷增加,抗生素在醫院中被廣泛使用。對嚴重感染的患者使用抗生素。它們也在外科手術前施用,以降低細菌污染的風險。與此一致的是,個體術後預防中抗生素的使用不斷增加,促進了市場的成長。除此之外,由於醫院多重抗藥性感染風險不斷上升,抗生素的消耗量不斷增加,也支撐了市場的成長。
北美洲
美國
加拿大
亞太
中國
日本
印度
韓國
澳洲
印尼
其他
歐洲
德國
法國
英國
義大利
西班牙
俄羅斯
其他
拉丁美洲
巴西
墨西哥
其他
中東和非洲
亞太地區表現出明顯的主導地位,佔據最大的抗生素市場佔有率
該報告還對所有主要區域市場進行了全面分析,其中包括北美(美國和加拿大);亞太地區(中國、日本、印度、韓國、澳洲、印尼等);歐洲(德國、法國、英國、義大利、西班牙、俄羅斯等);拉丁美洲(巴西、墨西哥等);以及中東和非洲。報告稱,亞太地區是最大的市場。
由於醫療基礎設施的改善,亞太地區佔據了最大的市場佔有率。與此一致的是,衛生條件差導致細菌感染的日益流行正在促進亞太地區市場的成長。除此之外,對能夠有效對抗多重抗藥性細菌的先進抗生素的需求不斷成長,也支撐了市場的成長。此外,大量的學名藥製造商存在正在推動該地區市場的成長。
該行業的主要參與者正在投資研發(R&D)活動,以發現和開發新的抗生素,並專注於抗生素抗藥性,擴大活動範圍,並提高抗生素的功效和安全性。除此之外,他們還與研究機構、學術組織和政府機構合作,利用他們的專業知識,解決與抗生素開發相關的挑戰,例如高成本和監管合規性。此外,抗生素公司正在積極推動抗生素管理計劃,鼓勵負責任和適當地使用抗生素,以避免過量和誤用。此外,公司擴大進行臨床試驗並遵守安全性和有效性標準,以獲得抗生素的監管批准。
艾爾建公司(艾伯維公司)
巴西利亞製藥公司
葛蘭素史克公司
強生公司
梅林塔療法
默克公司
納布里瓦治療公司
帕拉泰克製藥公司
輝瑞公司
賽諾菲公司
斯佩羅療法
四相製藥公司
2021年,諾華旗下山德士成功完成對葛蘭素史克(GSK)頭孢類抗生素業務的收購。此次收購為 Sandoz 提供了在 100 多個市場中三個知名品牌(Zinnat、Zinacef 和 Fortum)的權利。
2020年1月,默克宣布美國食品藥物管理局(FDA)已批准DIFICID(R)(fidaxomicin)口服混懸液的新藥申請(NDA)以及補充新藥申請(sNDA)用於治療6 個月及以上兒童艱難梭菌相關性腹瀉(CDAD) 的DIFICID 片劑。
The global antibiotics market size reached US$ 49.4 Billion in 2022. Looking forward, IMARC Group expects the market to reach US$ 62.6 Billion by 2028, exhibiting a growth rate (CAGR) of 4.0% during 2022-2028. The growing prevalence of pneumonia, tuberculosis, and other infectious diseases among individuals, rising occurrence of antimicrobial resistance (AMR), and technological advancements in biotechnology and drug discovery techniques are some of the major factors propelling the market.
Antibiotics are a class of medications that are used to treat bacterial infections. They are widely available in various forms, such as pills, capsules, injections, creams, and ointments. They either kill bacteria or inhibit their growth to effectively eliminate infections. They target specific mechanisms or structures within bacterial cells and interfering with their vital functions and preventing their reproduction. Besides this, they assist in enhancing the immune system of individuals. As a result, antibiotics are utilized to treat various diseases, such as urinary tract infections (UTI), respiratory tract infections, skin infections, and certain sexually transmitted diseases among individuals.
At present, the increasing prevalence of numerous chronic diseases among the masses around the world is contributing to the growth of the market. Additionally, the wide availability of antibiotics through online and offline stores across the globe is strengthening the growth of the market. Apart from this, the growing demand for topical antibiotics, as they minimize the risk of surgical site infections among individuals, is positively influencing the market. Moreover, the increasing employment of antibiotics in livestock farming to safeguard animal health and welfare and support food safety is bolstering the growth of the market. In line with this, the rising demand for antibiotics among the geriatric population is supporting the growth of the market. Furthermore, the increasing consumer awareness about preventive healthcare measures is impelling the growth of the market.
Rising prevalence of infectious diseases
There is a rise in the prevalence of infectious diseases, such as pneumonia, tuberculosis, urinary tract infections (UTI), gastrointestinal infections, and sepsis, among the masses across the globe. People are increasingly suffering from these diseases due to inadequate sanitation, which contributes to the spread of bacterial infections. In addition, the emergence of drug-resistant bacteria is increasing the demand for antibiotics. There is a rise in the demand for effective antibiotics that assist in treating these infections. Antibiotics are specifically designed to target and eliminate bacterial infections. They effectively kill bacteria in the body and promote healing among individuals. Furthermore, antibiotics are used under the guidance of healthcare professionals to optimize patient outcomes.
Increasing occurrence of antimicrobial resistance (AMR)
There is a rise in the occurrence of antimicrobial resistance (AMR) across the globe, which is driving the antibiotics market. AMR occurs when bacteria, viruses, parasites, or fungi evolve and become resistant to the drugs used to treat them. It reduces the effectiveness of antibiotics and causes longer and more severe infections, increased healthcare costs, and high mortality rates among individuals. Overuse and misuse of antibiotics are contributing to the development of drug-resistant bacteria, which makes traditional antibiotics less effective. In addition, multidrug-resistant strains, such as Methicillin-resistant Staphylococcus aureus (MRSA) and Carbapenem-resistant Enterobacteriaceae (CRE), are more prevalent. This necessitates the development of new antibiotics or alternative treatments to combat these resistant strains.
Technological advancements in antibiotics
Innovations in biotechnology, molecular biology, and drug discovery techniques assist in improving the efficiency and effectiveness of antibiotic development. Genomics and high-throughput screening allow the identification of potential drug targets and the screening of large compound libraries. Moreover, computer-aided drug design enables the prediction of drug efficacy and optimizes antibiotic candidates. These technological advancements streamline the antibiotic discovery process and reduce the time and costs associated with traditional methods. Additionally, advancements in diagnostic techniques, such as rapid pathogen identification and susceptibility testing, assist in appropriate antibiotic selection and prescribing that provides enhanced patient outcomes. Furthermore, technological advancements aid in the development of new and more potent antibiotics to address infectious diseases and antimicrobial resistance.
IMARC Group provides an analysis of the key trends in each segment of the global antibiotics market report, along with forecasts at the global, regional and country levels from 2023-2028. Our report has categorized the market based on action mechanism, drug class, spectrum of activity, route of administration and end user.
Cell Wall Synthesis Inhibitors
Protein Synthesis Inhibitors
DNA Synthesis Inhibitors
RNA Synthesis Inhibitors
Mycolic Acid Inhibitors
Others
Cell wall synthesis inhibitors represent the largest market segment
The report has provided a detailed breakup and analysis of the market based on the action mechanism. This includes cell wall synthesis inhibitors, protein synthesis inhibitors, DNA synthesis inhibitors, RNA synthesis inhibitors, mycolic acid inhibitors, and others. According to the report, cell wall synthesis represented the largest segment.
Cell wall synthesis is a class of antibiotics that target the bacterial cell wall. These antibiotics interfere with the process of cell wall synthesis, which causes cell wall damage and eventual bacterial death. In addition, penicillin, cephalosporins, and carbapenems are some of the cell wall synthesis inhibitors. They work by inhibiting enzymes called penicillin-binding proteins (PBPs) that are involved in the cross-linking of peptidoglycan chains. Moreover, cell wall synthesis inhibitors are particularly effective against gram-positive bacteria due to their thicker peptidoglycan layer, which provides a greater target for disruption.
Cephalosporin
Penicillin
Fluoroquinolone
Macrolide
Carbapenem
Aminoglycoside
Others
Penicillin accounts for the majority of the market share
The report has provided a detailed breakup and analysis of the market based on the drug class. This includes cephalosporin, penicillin, fluoroquinolone, macrolide, carbapenem, aminoglycoside, and others. According to the report, penicillin represented the largest segment.
Penicillin is a widely used class of antibiotics that belongs to the beta-lactam drug class. It works by inhibiting the synthesis of bacterial cell walls that causes cell wall damage and bacterial death. It is considered an essential medicine and is widely available as generic drugs. Apart from this, it is widely used in various healthcare settings, such as hospitals, clinics, and outpatient settings. In addition, the rising utilization of penicillin, as it is effective against various bacterial infections, is contributing to the growth of the market.
Broad-Spectrum Antibiotics
Narrow-Spectrum Antibiotics
Broad-spectrum antibiotics hold the biggest market share
The report has provided a detailed breakup and analysis of the market based on the spectrum of activity. This includes broad-spectrum antibiotics and narrow-spectrum antibiotics. According to the report, broad-spectrum antibiotics represented the largest segment.
Broad-spectrum antibiotics are a class of antibiotics that exhibit activity against a wide range of bacteria, such as gram-positive and gram-negative bacteria. In line with this, the rising adoption of broader spectrum antibiotics, as they are effective against a broader range of microorganisms compared to narrow-spectrum antibiotics, is bolstering the growth of the market. Apart from this, broad-spectrum antibiotics assist in treating infections when the causative bacteria are unknown or when the infection involves multiple bacterial species. The appropriate use of broad-spectrum antibiotics minimizes the risks of infections in the body.
Oral
Parenteral
Topical
Others
Parenteral dominates the market segment
The report has provided a detailed breakup and analysis of the market based on the route of administration. This includes oral, parenteral, topical, and others. According to the report, parenteral represented the largest segment.
Parenteral antibiotics are administered via routes other than the digestive tract, such as intravenous (IV), intramuscular (IM), or subcutaneous (SC) routes. These routes allow for direct delivery of the medication into the bloodstream or deep tissues, bypassing the gastrointestinal system. In addition, parenteral antibiotics provide rapid and predictable drug absorption and immediate therapeutic effect. They are also suitable for patients with compromised gastrointestinal function. Apart from this, it allows for accurate dosing and is particularly beneficial in cases where high drug concentrations are needed or when oral administration is not possible.
Hospitals
Specialty Clinics
Others
Hospitals accounted for the largest market share
The report has provided a detailed breakup and analysis of the market based on the end user. This includes hospitals, specialty stores, and others. According to the report, hospitals represented the largest segment.
Antibiotics are widely consumed in hospitals due to the increased number of patients staying in this healthcare setting. Antibiotics are administered to patients admitted with severe infections. They are also administered before surgical procedures to reduce the risk of bacterial contamination. In line with this, the rising utilization of antibiotics among individual post-surgical prophylaxis is contributing to the growth of the market. Apart from this, the increasing consumption of antibiotics due to the rising risk of multidrug-resistant infections in hospitals is supporting the growth of the market.
North America
United States
Canada
Asia-Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
Asia Pacific exhibits a clear dominance, accounting for the largest antibiotics market share
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, Asia Pacific represented the largest market.
Asia Pacific held the biggest market share due to the improved healthcare infrastructure. In line with this, the growing prevalence of bacterial infections to poor sanitation is contributing to the growth of the market in the Asia Pacific region. Apart from this, the increasing demand for advanced antibiotics that can effectively combat multidrug-resistant bacteria is supporting the growth of the market. Furthermore, the presence of a large number of generic drug manufacturers is propelling the growth of the market in the region.
Key players in the industry are investing in research and development (R&D) activities to discover and develop new antibiotics and focusing on antibiotic resistance, expanding the spectrum of activity, and improving the efficacy and safety profiles of antibiotics. Apart from this, they are engaging in collaboration with research institutions, academic organizations, and government bodies to leverage their expertise and address the challenges associated with antibiotic development, such as high costs and regulatory compliances. Moreover, antibiotic companies are actively promoting antibiotic stewardship programs that encourage responsible and appropriate use of antibiotics to avoid overdosage and misusage. Furthermore, companies are increasingly conducting clinical trials and adhering to safety and efficacy standards to obtain regulatory approvals for their antibiotics.
Allergan Plc (AbbVie Inc.)
Basilea Pharmaceutica AG
GlaxoSmithKline Plc
Johnson & Johnson
Melinta Therapeutics
Merck & Co. Inc.
Nabriva Therapeutics Plc
Paratek Pharmaceuticals Inc.
Pfizer Inc.
Sanofi SA
Spero Therapeutics
Tetraphase Pharmaceuticals
In 2021, Sandoz, a Novartis division, successfully completed the acquisition of GlaxoSmithKline's (GSK) cephalosporin antibiotics business. This acquisition provides them rights to three established brands (Zinnat, Zinacef and Fortum) in more than 100 markets to Sandoz.
In January 2020, Merck & Co. Inc. announced that U.S. Food and Drug Administration (FDA) has approved a New Drug Application (NDA) for DIFICID® (fidaxomicin) for oral suspension, and a supplemental New Drug Application (sNDA) for DIFICID tablets for the treatment of Clostridioides (formerly Clostridium) difficile-associated diarrhea (CDAD) in children aged six months and older.