單細胞分析：技術成長機會

Single-cell Analysis: Technology Growth Opportunities

出版日期: 2023年11月30日 | 出版商:

Frost & Sullivan | 英文 68 Pages | 商品交期: 最快1-2個工作天內

價格

簡介目錄

單細胞分析的技術進步將帶來新的診斷和治療機會。

單細胞分析可以透過研究細胞內基因組學、轉錄組學、蛋白質組學、代謝組學和其他細胞間相互作用來診斷異質細胞群樣本的狀態。它將幫助我們更好地了解腫瘤微環境，並根據新發現的不同腫瘤類型的知識來開發藥物。這種分析方法產生的大量資料可以深入了解基因表現和決定病理的其他因素。

這種方法引起了投資者和研究機構的關注，因為它推進了現有的診斷和藥物研發方法，但它也存在技術挑戰（必須透過技術平台的進步來克服），並且存在一個以大測序為主導的高度競爭的環境已經成長為提供小公司無法提供的端到端解決方案的公司。

許多公司在基因組和轉錄組層面進行單細胞分析，但只有少數公司進行蛋白質體學和多組體學單細胞分析。技術的進步有助於避免繁瑣的過程，例如在文庫製備過程中透過獨特的條碼過程進行單細胞分離。空間體學和活細胞測序等現代方法也補充了現有的單細胞分析過程。這種方法的主要挑戰之一是測序結果的資料分析，這是透過雲端平台解決的，無需任何生物資訊經驗即可操作。使用這種分析方法對尚未理解的主題進行研究有很大的空間，我們確信這種方法將在未來十年內顯著成長，希望不僅能改善癌症的診斷，還能改善其他疾病的診斷。

該研究確定了該行業的挑戰、促進因素、新技術平台和成長機會，並預測了成長前景。它還確定了利益相關相關人員和市場參與企業應該利用的著名併購、資金籌措和合作夥伴關係，並概述了相關人員生態系統。

過去五年平台開發的增加
單細胞分析應用擴展到腫瘤學之外
單細胞和空間分析的改進將透過新發現增強精準醫學
相關人員生態系統
單細胞分析策略夥伴關係
資金籌措生態系統
主導單細胞和空間基因組併購的綜合解決方案提供商
與單細胞分析相關的專利申請和津貼穩步增加
單細胞分析生態系的形勢

成長機會宇宙

成長機會 1：單細胞分離和文庫製備的進步可改善整體工作流程
成長機會 2：將單細胞分析的範圍擴展到精準腫瘤學之外
成長機會 3：改進單細胞資料科學，快速獲得定序資料中有意義的見解

附錄

技術成熟度等級 (TRL)：解釋

下一步

簡介目錄

Product Code: DAC1

Technological advancements in single-cell analysis propel new diagnostic and therapeutic opportunities.

Single-cell analysis can diagnose a condition in heterogenous cell population samples by studying genomics, transcriptomics, proteomics, metabolomics, and other cellular interactions in cells. It helps to understand a tumor microenvironment better and develop drugs based on newly uncovered knowledge of various types of tumors. The rich data provided through this method of analysis gives in-depth insight into gene expression and other factors determining a pathological condition.

As this method is an advancement to already existing methods of diagnosis and drug discovery, it is gaining the attention of investors and research institutions, although there are a few challenges in terms of technology (which must be navigated through advancements in technology platforms) and the monopoly of large sequencing companies that have grown to provide end-to-end solutions that cannot be provided by small and mid-sized companies, creating an intensely competitive environment.

Many companies perform single-cell analysis at the genomic and transcriptomic levels; however, only a few do the same in proteomic and multi-omics single-cell resolution. Technology advancements are helping to bypass tedious processes, such as single-cell separation through a unique barcoding process during library preparation. Modern methods, including spatial omics and live-cell sequencing, are also complementing the existing single-cell analysis process. One of the major challenges in this method is the data analysis of sequenced results, which is being tackled through cloud platforms that operate without the need for prior bioinformatics experience. There is significant scope for research on topics that are underexplored in this method of analysis, which ensures good growth of this technique in the next decade and promises improved diagnosis not only for cancer but also for other diseases.

This study identifies the challenges, drivers, new technology platforms, and growth opportunities in this space and foresees a growth outlook. It also provides an overview of the stakeholder ecosystem, identifying notable mergers and acquisitions, funding, and partnerships for stakeholders and market participants to leverage.

Strategic Imperatives

Why Is It Increasingly Difficult to Grow?The Strategic Imperative 8™: Factors Creating Pressure on Growth
The Strategic Imperative 8™
The Impact of the Top 3 Strategic Imperatives on the Single-cell Analysis Industry
Growth Opportunities Fuel the Growth Pipeline Engine™
Research Methodology

Scope and Segmentation

Context and Scope of Analysis
Segmentation

Growth Opportunity Analysis

Growth Drivers
Growth Restraints

Introduction

Introduction to Single-cell Analysis and the Need for It
Single-cell Sequencing Process Development Time Line
Single-cell Analysis Applications

Technology Snapshot

Single-cell Isolation
Single-cell Isolation Technologies-Commercialized Solutions
Single-cell Library Preparation
Single-cell Library Preparation-Innovation
Single-cell Sequencing
Single-cell Sequencing Platforms
Single-cell Bioinformatics
Bioinformatics Tools Used in Single-cell Analysis

Technology Enablers Bolstering Single-cell Analysis

Growing Influence of AI and ML in Single-cell Analysis
Spatial Omics Technologies Evolving to Compliment Single-cell Analysis Technology
Microfluidic Technologies in Single-cell Analysis

Recent Technological Advancements in Single-cell Analysis

Live-cell Sequencing or Temporal Analysis Providing Spatial Information Without Damaging Cells
A Combination of Single-cell and Other Technologies Providing Deeper Insights for Therapy Development
3D Genome Technologies Offering a Better Depiction of the Cell Environment and Its Heterogeneity
Single-cell Exploratory Research Landscape
Snapshot of University Research in Single-cell Analysis

Trends and Developments in Single-cell Analysis

Increasing Number of Platform Developments in the Last 5 Years
Applications of Single-cell Analysis to Expand Beyond Oncology
Improved Single-cell and Spatial Analysis to Strengthen Precision Medicine Through New Discoveries
Stakeholder Ecosystem
Single-cell Analysis Strategic Partnerships
Funding Ecosystem
Integrated Solution Providers Dominating M&As in Single-cell and Spatial Genomics
Steadily Increasing Patent Filings and Grants for Single-cell Analysis
Landscape of the Single-cell Analysis Stakeholder Ecosystem

Growth Opportunity Universe

Growth Opportunity 1: Advances in Single-cell Isolation and Library Preparation Improving Overall Workflow
Growth Opportunity 2: Widening Applicability of Single-cell Analysis Beyond Precision Oncology
Growth Opportunity 3: Improvement in Single-cell Data Science for Rapid and Meaningful Insights of Sequenced Data