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市場調查報告書

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1345372

全球組織工程市場 - 2023-2030

Global Tissue Engineering Market - 2023-2030

出版日期: 2023年09月06日 | 出版商:

DataM Intelligence | 英文 195 Pages | 商品交期: 約2個工作天內

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簡介目錄

市場概況

2022年全球組織工程市場規模預計為12億美元，預計到2030年將達到17億美元，2023-2030年預測期間年複合成長率為4.8%。由於 3D 生物列印技術具有根據患者特定組織和器官創建複雜組織結構的精確潛力，因此向 3D 生物列印技術的轉變等趨勢預計將主導全球組織工程市場。

全球組織工程市場近年來顯著成長，預計將繼續呈上升趨勢。受幹細胞治療、器官晶片技術、基因編輯和 CRISPR 技術等顯著潛力的影響，市場正在經歷一個轉型期。

此外，神經系統疾病、心血管和骨科疾病的患病率不斷上升、3D生物列印和幹細胞療法等技術進步、人口老齡化加劇、道路事故和創傷相關損傷病例不斷增加對骨植入物的需求不斷成長，這些都推動了組織工程的發展市場規模。

使用組織工程方法治療疾病的研究活動不斷成長，以及成熟的生物製藥和製藥公司的存在，是北美地區需求的一些因素，這些地區的重要競爭對手包括Zimmer Biomet、Stryker Corporation、CollPlant Biotechnologies Ltd. 和其他在該地區積極營運的公司。市場。

市場動態

器官移植需求的不斷成長推動組織工程市場的成長

器官移植需求的不斷成長正在推動組織工程市場的發展。器官捐獻者短缺問題日益嚴重，已成為醫療保健領域的一個重大問題。例如，根據衛生資源和服務管理局 2023 年的統計數據，全國移植等待名單上約有 104,234 人。每天都有超過 17 人在等待器官移植期間死亡。此外，每10分鐘就有報導稱需要進行器官移植。此外，隨著這些數位的增加，由於器官捐獻者稀缺，器官供應變得越來越困難。

因此，組織工程可以通過協助人體組織工程來替代受損的組織和器官，在解決器官捐獻者稀缺問題上發揮重要作用。組織工程師通過結合生物材料、細胞和生物活性化學物質來開發可輕鬆融入人體的功能組織。皮膚、血管、膀胱、心臟和其他類型的組織已經被組織工程化並用於治療人類疾病。由於上述所有因素，預計市場在預測期內將會成長。

不斷成長的技術進步和合作將推動組織工程市場的成長

通過與不同領域的市場領導者合作，組織工程技術不斷進步，預計將推動市場需求。例如，根據ISS國家實驗室2023文章，維克森林再生醫學研究所與RegenMed開發組織合作，旨在利用國際空間站（ISS）國家實驗室的微重力條件發射生物工程肝臟和腎臟通過Axiom Space 的Ax- 2 任務將建築物送入太空。研究人員希望通過研究微重力如何改變這些組織的血管化來改變器官移植和疾病模型。

因為，與傳統的組織工程不同，微重力條件可以實現無支架組織的發育，從而有可能簡化和改進整個過程。因此，該項目的成功可以顯著減少器官移植等候名單，推進治療測試的疾病模型，並為創新細胞療法提供資源，揭示發展潛在的合作和進步如何推動組織工程領域的變革性進展。

慢性病患病率上升將推動組織工程市場成長

全球慢性疾病的日益流行預計將推動對有效組織工程技術的需求。例如，根據世界衛生組織2022年報告，慢性病是遺傳、生理、環境和行為因素的綜合作用。每年約有 410 億人死於這些疾病，佔全球總死亡人數的 74%。每年因心血管疾病死亡的人數最多，達 179 億人，其次是癌症。

此外，隨著癌症發病率的上升，需要3D生物列印等有效技術來對抗不斷生長的癌細胞。例如，2023年EurekAlert組織發表的一篇文章中，韓國機械材料研究所（KIMM）開發出了世界上第一個3D生物列印技術，將增強NK免疫細胞的功能。這項新技術有望提高癌症治療的有效性。因此，由於上述因素，預計市場在預測期內將受到推動，

組織工程技術相關的高成本將阻礙市場的成長

由於實驗室或設施的初始投資、經常性費用以及移植本身的成本等多種因素，與組織工程技術相關的高成本是該市場的一個關鍵限制。以組織工程策略為例，實驗室成本為 50,700 美元。相比之下，採購組織程序的設施投資成本為 168,750 美元。組織工程結構的製造成本也可能很高。

此外，細胞和組織捐贈計劃的短缺可能導致組織工程的高成本。對私人和政府資金的需求、過度的醫療保健支出以及使用組織工程策略治療糖尿病足潰瘍的高額費用都可能導致組織工程的高成本。由於上述問題，預計組織工程市場在預測期內將受到重大限制。

Market Overview

Global Tissue Engineering Market size is valued at USD 1.2 billion in 2022, it is expected to reach USD 1.7 billion by 2030, with growth at a CAGR of 4.8% over the forecast period 2023-2030. The trend such as the shift towards 3D bioprinting technology due to its precise potential to create intricate tissue structures according to patient-specific tissues and organs is expected to dominate the global tissue engineering market.

The global tissue engineering market has grown significantly in recent years and is projected to continue on its upward trend. The market is undergoing a transformational period, influenced by several significant trends such as remarkable potential shown by stem cell therapy, organ-on-chip technology, and gene editing and CRISPR technology.

Furthermore, the rising prevalence of neurological disorder, cardiovascular and orthopedic disorders, technological advancements such 3D bioprinting and stem cell therapies, increasing aging population, growing demand for bone implants due to the increasing road accident and trauma related injury cases are driving up the tissue engineering market size.

The growing research activities for treating disease using tissue engineering approach and presence of establish biopharmaceutical and pharmaceutical companies are some of the factors in demand from North American regions with significant competitors like Zimmer Biomet, Stryker Corporation, CollPlant Biotechnologies Ltd., and others actively operating in the market.

Market Dynamics

The Increasing Demand for Organ Transplant to Drive the Growth of the Tissue Engineering Market

The increasing need for organ transplants is propelling the tissue engineering market. The shortage of organ donors is escalating and has become a significant issue in the healthcare sector. For instance, according to Health Resources and Services Administration 2023 statistics around 104,234 individuals are on the national transplant waiting list. Every day, over 17 individuals die while waiting for organ transplants. Furthermore, every 10 minutes, it is reported that an organ transplant is required. In addition, as these numbers rise, it is becoming increasingly difficult to supply organs due to a scarcity of organ donors.

Tissue engineering can thus play a significant part in addressing the scarcity of organ donors by assisting in the engineering of human tissue that will replace damaged tissues and organs. Tissue engineers develop functional tissues that integrate easily into the body by combining biomaterials, cells, and bioactive chemicals. Skin, blood vessels, bladders, hearts, and other types of these tissues have already been tissue engineered and employed in the therapy of human disease. As a result of all of the above, the market is expected to grow during the forecast period.

Growing Technological Advancements and Collaborations will Drive the Tissue Engineering Market Growth

The growing technological advancement in tissue engineering techniques by collarating with different field market leaders is expected to drive the demand for the market. For instance, according to ISS National Laboratory 2023 article, the collaboration between the Wake Forest Institute for Regenerative Medicine and the RegenMed Development Organization, it aims to use the microgravity conditions of the International Space Station (ISS) National Laboratory to launch bioengineered liver and kidney constructions into space via Axiom Space's Ax-2 mission. The Researchers want to transform organ transplantation and disease modeling by studying how microgravity alters the vascularization of these tissues.

Because, unlike traditional tissue engineering, microgravity conditions enable scaffold-free tissue development, potentially simplifying and improving the entire process. Thus, success in this project could significantly reduce organ transplant waitlists, advance disease modeling for therapy testing, and provide resources for innovative cell therapies, revealing how developing potential collaborations and advancements can drive transformative progress in the tissue engineering field.

Rising Prevalence of Chronic Disease will Drive the Tissue Engineering Market Growth

The growing prevalence of chronic disease across the globe is expected to drive the demand for effective tissue engineering techniques. For instance, according to World Health Organization report of 2022, chronic disease is a combination of genetic, physiological, environmental and behavioural factors. Every year approximately 41 Billion people die due to these disease that accounts 74% of total deaths globally. Patients suffering from cardiovascular disease accounts highest number of 17.9 billion deaths every year followed by cancer.

Furthermore, as the prevalence of cancer is rising, there is need of effective technology such as 3D bioprinting to combact with growing cancer cells. For instance, an article published by EurekAlert organization in 2023, Korea Institute of Machinery and Materials (KIMM) has developed the world's first 3D bioprinting technology that will enhance the functioning of NK immune cells. This New technology expected to improve effectiveness of cancer treatment. Thus, owing to the above factors the market is expected to drive over the forecast period,

High Cost Associated with the Tissue Engineering Technique Will Hamper the Growth of the Market

The high cost associated with the tissue engineering technique is a critical limitation for this market due to several factors, such as the initial investment for the laboratory or facility, recurrent fees, and the cost of the transplant itself. In the tissue engineering strategy, for example, the laboratory costs $50,700. In comparison, the facility investment cost for the procured-tissue procedure was US$168,750. Manufacturing costs for tissue-engineered structures can also be costly.

Additionally, the shortage of cell and tissue donation programs may contribute to tissue engineering's high cost. The demand for private and government funding, excessive healthcare spending, and the high expense of treating diabetic foot ulcers using a tissue engineering strategy may all contribute to the high cost of tissue engineering. As a result of the issues mentioned above, the tissue engineering market is expected to experience significant restraints over the forecast period.

Segment Analysis

The global tissue engineering market is segmented based on material type, application, end user and region.

Owing to the Growing Prevalence of Bone Disorders, the Orthopedics Segment Accounted for Approximately 43.2% of the Tissue Engineering Market Share

The orthopedics segment is poised to dominate the tissue engineering market due to growing focus on applying tissue engineering techniques to address orthopedic challenges. This segment is expected to grow owing to the factors such as rising prevalence bone and joint injuries, degenerative conditions, and musculoskeletal disorders, increasing aging population, and growing technological advancements.

For instance, according to the World Health Organization 2022 report, approximately 1.71 billion people are suffering from musculoskeletal conditions globally. This has led to leading causes of disability worldwide, among which low back pain has been the major cause of disability in more than 160 countries. Tissue engineering plays an important role by offering innovative solutions to repair and regenerate damaged bone and cartilage tissues.

Moreover, many companies are utilizing technological advancements such as 3D bioprinting using tissue engineering. For instance, Curiteva, the creator of the world's first 3D printed interbody spinal implants, has granted the medical device a restricted commercial distribution. For spine surgery, the Huntsville-based technology and manufacturing company uses 3D-printed spinal implants. Curiteva's recently FDA-approved Inspire platform is used to create the implants Thus, owing to the above factors the segment is expected to dominate over the forecast period.

Geographical Penetration

North America Accounted for Approximately 37.5% of the Market Share in 2022, Owing to the Rising Prevalence of Geriatric Population

North America, particularly the U.S., dominates the global tissue engineering market due to presence of huge number of key players settled in the region, technological advancements, and high research activities along with developments of 3D bioprinting, organ-on-chip, and stem cell technologies by major players in the area.

The demand for tissue engineering in the pharmaceutical industry is driven by an increase in the number of technologies and rising number of geriatric populations in the region. For instance, according to United States Census Bureau statistics, in U.S. 1 in 6 people are aging over 65. Moreover, in 2020 older population reached about 55.8 Billion or 16.8% of U.S. total population. Thus, tissue engineering will aid in restoring and improving the function of degenerated tissues, catering to the needs.

Moreover, the R&D process in this region is well established that creates opportunities for researcher to discover different technologies. For instance, in June 2023, Emulate, a company that creates in vitro drug research models, has introduced a new device dubbed Chip-A1. Chip-A1 is an extension of the company's Organ-on-a-Chip technology, which allows researchers to model human organs in vitro more accurately. The new chip improves in vitro modeling capabilities for cancer and cosmetics research, which require more precise models of human organs. The Chip-A1 technology is expected to find applications in cancer, cosmetics, and respiratory areas. Thus, owing to above factors the region is expected to grow over the forecast period.

Competitive Landscape

The major global players in the tissue engineering market include Zimmer Biomet, Stryker Corporation, 3D BioFibR Inc., Integra LifeSciences Corporation, CollPlant Biotechnologies Ltd., AbbVie (Allergan Aesthetics), Becton, Dickinson and Company, Athersys, Inc., BioTissue., Japan Tissue Engineering Co., Ltd, and among others.

COVID-19 Impact Analysis

The COVID-19 pandemic began in December 2019 with the SARS-CoV-2 virus in Wuhan, China, quickly spreading throughout the world, creating a significant impact on the tissue engineering market. The virus spreads easily by droplets from infected people, resulting in many illnesses. COVID-19 can cause major organ damage by affecting many organs. Tissue engineering approaches can be used to fix this, in which experts create novel ways to heal injured organs.

However, due to COVID-19, it has been difficult to obtain the materials needed for the present research. Shipping issues caused delays and cancellations of essential supplies, making it difficult for researchers and businesses to continue their work. Because of the pandemic, this condition hampered scientific development and had a significant impact on tissue engineering.

Russia-Ukraine War Impact Analysis

The Russia-Ukraine conflict has had a negative impact on the tissue engineering sector. The conflict has hampered the chances of global economic recovery, which has hampered the expansion of the tissue engineering sector. The conflict has also produced economic disruption, which has reduced demand for tissue engineering products. Thus, the conflict will create a major impact on the tissue engineering market over some period.

By Material Type

Synthetic Materials

Polymers

Hydrogels

Ceramics

Composites

Biologically Derived Materials

Extracellular Matrix (ECM) Proteins

Fibrin

Collagen

Silk

Others

By Application

Orthopedics
Musculoskeletal & Spine
Neurology
Cardiology
Skin & Integumentary
Others

By End-User

Hospitals
Academic and Research Institutes
Others

By Region

North America

U.S.

Canada

Mexico

Europe

Germany

U.K.

France

Spain

Italy

Rest of Europe

South America

Brazil

Argentina

Rest of South America

Asia-Pacific

China

India

Japan

Australia

Rest of Asia-Pacific

Middle East and Africa

Key Developments

On June 13, 2023, the Indian Drugs Controller has approved the first indigenously developed tissue engineering scaffold from mammalian organs by Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), an animal-derived Class D Biomedical Device that can rapidly heal skin wounds at low cost with minimal scarring.
On January 16, 2023, 3DBioFibR, a leading tissue engineering pioneer, announced the release of two new collagen fibre solutions, CollaFibR and CollaFibR 3D scaffold. These off-the-shelf solutions, created using 3D BioFibR's exclusive and revolutionary dry-spinning technology to generate collagen fibres at commercial scales, offer considerable advantages for tissue engineering and tissue culture applications and are now for sale.
On January 16, 2023, BioMed X, an independent German biomedical research institute, announced that its ongoing research collaboration with AbbVie has been extended. This marks the opening of the first BioMed X Institute in the United States, which will be in New Haven, Connecticut. The new US-based research cooperation will focus on immunology and tissue engineering, following a first cooperative research study on Alzheimer's disease at the BioMed X Institute in Heidelberg, Germany.

DMI Opinion

The global tissue engineering market is expected to grow more rapidly as a result of the shift toward 3D bioprinting technology for accurate tissue structure development, with trends such as stem cell therapy, organ-on-chip technology, and gene editing driving this expansion. Rising neurological, cardiovascular, and orthopedic illnesses, as well as technical advancements such as 3D bioprinting and stem cell therapies, an aging population, and an increased need for implants due to trauma cases, all contribute to the market's growth.

North America is seeing demand, led by big players, while the necessity for organ transplantation fuels growth. However, large expenses, an absence of contributors, and geopolitical tensions pose difficulties. The orthopedics market is thriving due to bone problems, but COVID-19 and geopolitical issues are hampering progress. Finally, the tissue engineering market is characterized by new trends and opportunities.

Why Purchase the Report?

To visualize the global tissue engineering market segmentation based on material type, application, end user, and region as well as understand key commercial assets and players.
Identify commercial opportunities by analyzing trends and co-development.
Excel data sheet with numerous data points of tissue engineering market-level with all segments.
PDF report consists of a comprehensive analysis after exhaustive qualitative interviews and an in-depth study.
Product mapping is available in excel consisting of key products of all the major players.

The global tissue engineering market report would provide approximately 53 tables, 54 figures and 195 Pages.

Target Audience 2023

Manufacturers/ Buyers
Industry Investors/Investment Bankers
Research Professionals
Emerging Companies

1. Methodology and Scope

1.1. Research Methodology
1.2. Research Objective and Scope of the Report

2. Definition and Overview

3. Executive Summary

3.1. Snippet by Material Type
3.2. Snippet by Application
3.3. Snippet by End User
3.4. Snippet by Region

4. Dynamics

4.1. Impacting Factors
- 4.1.1. Drivers
  - 4.1.1.1. The Increasing Demand for Organ Transplant
  - 4.1.1.2. The Growing Technological Advancements and Collaborations
- 4.1.2. Restraints
  - 4.1.2.1. The High Cost Associated with the Tissue Engineering Technique
- 4.1.3. Opportunity
  - 4.1.3.1. Increasing Demand for Personalized Medicine
- 4.1.4. Impact Analysis

5. Industry Analysis

5.1. Porter's 5 Forces Analysis
5.2. Supply Chain Analysis
5.3. Pricing Analysis
5.4. Regulatory Analysis

6. COVID-19 Analysis

6.1. Analysis of COVID-19
- 6.1.1. Scenario Before COVID-19
- 6.1.2. Scenario During COVID-19
- 6.1.3. Scenario Post COVID-19
6.2. Pricing Dynamics Amid COVID-19
6.3. Demand-Supply Spectrum
6.4. Government Initiatives Related to the Market During Pandemic
6.5. Manufacturers Strategic Initiatives
6.6. Conclusion

7. By Material Type

7.1. Introduction
- 7.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material Type
- 7.1.2. Market Attractiveness Index, By Material Type
7.2. Synthetic Materials*
- 7.2.1. Introduction
- 7.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
  - 7.2.2.1. Polymers
  - 7.2.2.2. Hydrogels
  - 7.2.2.3. Ceramics
  - 7.2.2.4. Composites
7.3. Biologically Derived Materials
7.4. Others

8. By Application

8.1. Introduction
- 8.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 8.1.2. Market Attractiveness Index, By Application
8.2. Orthopedics*
- 8.2.1. Introduction
- 8.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
8.3. Musculoskeletal & Spine
8.4. Neurology
8.5. Cardiology
8.6. Skin & Integumentary
8.7. Others

9. By End User

9.1. Introduction
- 9.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 9.1.2. Market Attractiveness Index, By End User
9.2. Hospitals*
- 9.2.1. Introduction
- 9.2.2. Market Size Analysis and Y-o-Y Growth Analysis (%)
9.3. Hospitals
9.4. Academic and Research Institutes
9.5. Others

10. By Region

10.1. Introduction
- 10.1.1. Market Size Analysis and Y-o-Y Growth Analysis (%), By Region
- 10.1.2. Market Attractiveness Index, By Region
10.2. North America
- 10.2.1. Introduction
- 10.2.2. Key Region-Specific Dynamics
- 10.2.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material Type
- 10.2.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 10.2.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 10.2.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
  - 10.2.6.1. U.S.
  - 10.2.6.2. Canada
  - 10.2.6.3. Mexico
10.3. Europe
- 10.3.1. Introduction
- 10.3.2. Key Region-Specific Dynamics
- 10.3.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material Type
- 10.3.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 10.3.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 10.3.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
  - 10.3.6.1. Germany
  - 10.3.6.2. U.K.
  - 10.3.6.3. France
  - 10.3.6.4. Spain
  - 10.3.6.5. Italy
  - 10.3.6.6. Rest of Europe
10.4. South America
- 10.4.1. Introduction
- 10.4.2. Key Region-Specific Dynamics
- 10.4.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material Type
- 10.4.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 10.4.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 10.4.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
  - 10.4.6.1. Brazil
  - 10.4.6.2. Argentina
  - 10.4.6.3. Rest of South America
10.5. Asia-Pacific
- 10.5.1. Introduction
- 10.5.2. Key Region-Specific Dynamics
- 10.5.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material Type
- 10.5.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 10.5.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User
- 10.5.6. Market Size Analysis and Y-o-Y Growth Analysis (%), By Country
  - 10.5.6.1. China
  - 10.5.6.2. India
  - 10.5.6.3. Japan
  - 10.5.6.4. Australia
  - 10.5.6.5. Rest of Asia-Pacific
10.6. Middle East and Africa
- 10.6.1. Introduction
- 10.6.2. Key Region-Specific Dynamics
- 10.6.3. Market Size Analysis and Y-o-Y Growth Analysis (%), By Material Type
- 10.6.4. Market Size Analysis and Y-o-Y Growth Analysis (%), By Application
- 10.6.5. Market Size Analysis and Y-o-Y Growth Analysis (%), By End User

11. Competitive Landscape

11.1. Competitive Scenario
11.2. Market Positioning/Share Analysis
11.3. Mergers and Acquisitions Analysis

12. Company Profiles

12.1. Zimmer Biomet*
- 12.1.1. Company Overview
- 12.1.2. Product Portfolio and Description
- 12.1.3. Financial Overview
- 12.1.4. Key Developments
12.2. Stryker Corporation
12.3. 3D BioFibR Inc.
12.4. Integra LifeSciences Corporation
12.5. CollPlant Biotechnologies Ltd.
12.6. AbbVie (Allergan Aesthetics)
12.7. Becton, Dickinson and Company
12.8. Athersys, Inc.
12.9. BioTissue
12.10. Japan Tissue Engineering Co., Ltd.

LIST NOT EXHAUSTIVE