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1424472

G蛋白偶聯受體的全球市場：依產品類型、測定類型、應用、地區

Global G-Protein Coupled Receptors Market, By Product, By Assay Type, By Application, By Geography

出版日期: 2024年01月19日 | 出版商:

Coherent Market Insights | 英文 172 Pages | 商品交期: 2-3個工作天內

價格

簡介目錄

G蛋白偶聯受體的全球市場規模預計將從2023年的46.7億美元增加到2030年的78.6億美元，預測期內年複合成長率（CAGR）為7.7%。

報告範圍		報告詳情
基準年	2022年	2023/2024年市場規模	46.7億美元
過去的資料	2018-2021	預測期	2023-2030
預測期間2023/2024 至2030/2031年年複合成長率：	7.70%	2030/2031價值預測	78.6億美元

圖 1.2023年G蛋白偶聯受體的全球市場佔有率（%）（依地區）

G蛋白偶聯受體（GPCR）構成了一個重要且多樣化的細胞表面受體家族，在細胞內訊號傳導和通訊中發揮著非常重要的作用。這些受體是膜蛋白，具有不同的結構特徵，包括七個跨膜螺旋、一個細胞外 N 端和一個細胞內 C 端。七個跨膜結構域形成了一個特徵結構，通常被比喻為一束 α 螺旋，有利於受體插入細胞膜。 GPCR 的活化是透過與特定配體（包括激素、神經傳導物質和其他訊號分子）結合而觸發的。配體結合引起受體構象變化，導致活化。配體結合位點通常位於受體的細胞外 N 端，結合事件啟動細胞內訊號傳導連鎖。 GPCR 的特徵之一是它們與G蛋白的相互作用，G 蛋白是由 α、BETA 和 γ次單元組成的異三聚體複合物。當 GPCR 被活化時，受體會發生構象變化並催化G蛋白 α次單元上 GDP 和 GTP 的交換。G蛋白的活化會觸發下游訊號途徑並影響各種細胞反應。

市場動態：.

G蛋白偶聯受體（GPCR）市場是由癌症和心血管疾病等慢性病全球盛行率上升所推動的。 GPCR 在這些疾病中發揮重要作用，並作為藥物研發標靶積極研究。此外，不斷增加的藥物研發（R&D）支出、用於 GPCR藥物研發的先進篩檢技術的可用性以及不斷增加的 GPCR 標靶候選藥物的臨床管道推動市場機會。然而，開發和商業化 GPCR 藥物的高成本阻礙了市場開拓。此外，GPCR 活化下游的複雜訊號途徑也是一個挑戰。產業公司投資克服技術障礙，以充分發揮 GPCR 作為治療標靶的潛力。

本研究的主要特點

本報告對全球G蛋白偶聯受體市場進行了詳細分析，並列出了以2022年為基準年的預測期（2023-2030）的市場規模和年複合成長率。
揭示了各個細分市場的潛在商機，並為該市場說明了一系列有吸引力的投資提案。
提供了有關市場促進因素、限制因素、機會、新產品發布和核准、市場趨勢、區域前景、主要企業採取的競爭策略等的重要見解。
根據公司亮點、產品系列、主要亮點、性能和策略等參數，介紹了全球G蛋白偶聯受體市場的主要企業。
本報告的見解使行銷人員和公司負責人能夠就未來的產品發布、升級、市場擴張和行銷策略做出明智的決策。
全球G蛋白偶聯受體市場報告迎合了該行業的各種相關人員，如投資者、供應商、產品製造商、經銷商、新進業者和財務分析師。
透過用於分析全球G蛋白偶聯受體市場的各種策略矩陣，將促進相關人員的決策。

北美洲
美國
加拿大
歐洲
德國
英國
西班牙
法國
義大利
俄羅斯
其他歐洲國家
亞太地區
中國
印度
日本
澳洲
韓國
ASEAN
其他亞太地區
拉丁美洲
巴西
阿根廷
墨西哥
其他拉丁美洲
中東
海灣合作理事會國家
以色列
其他中東地區
非洲
北非
中部非洲
南非

第9章競爭形勢

公司簡介
- Thermo Fisher Scientific Inc.
- Eurofins Scientific
- QIAGEN
- WuXi AppTec
- Promega Corporation
- Abcam plc
- Merck KGaA
- PerkinElmer Inc.
- Enzo Biochem Inc.,
- BD

第10章

參考
調查方法
關於出版商

簡介目錄

Product Code: CMI6576

Global G-protein coupled receptors market size is expected to reach US$ 7.86 Bn by 2030, from US$ 4.67 Bn in 2023, exhibiting a compound annual growth rate (CAGR) of 7.7% during the forecast period.

Report Coverage		Report Details
Base Year:	2022	Market Size in 2023/2024:	US$ 4.67 Bn
Historical Data for:	2018 to 2021	Forecast Period:	2023 - 2030
Forecast Period 2023/2024 to 2030/2031 CAGR:	7.70%	2030/2031 Value Projection:	US$ 7.86 Bn

Figure 1. Global G-Protein Coupled Receptors Market Share (%), By Region, 2023

Global G-Protein Coupled Receptors Market - IMG1

G-protein coupled receptors (GPCRs) constitute a prominent and diverse family of cell surface receptors that play pivotal roles in cellular signaling and communication. These receptors are integral membrane proteins characterized by their distinct structural features, including seven transmembrane helices, an extracellular N-terminus, and an intracellular C-terminus. The seven transmembrane domains create a characteristic structure often likened to a bundle of alpha helices, facilitating the receptor's insertion into the cell membrane. The activation of GPCRs is triggered by the binding of specific ligands, which can include hormones, neurotransmitters, and other signaling molecules. Ligand binding induces conformational changes in the receptor, leading to its activation. The ligand-binding site is typically located at the extracellular N-terminus of the receptor, and the binding event initiates a cascade of intracellular signaling events. One of the hallmark features of GPCRs is their interaction with G-proteins, which are heterotrimeric complexes consisting of alpha, beta, and gamma subunits. Upon activation of the GPCR, the receptor undergoes conformational changes that allow it to catalyze the exchange of GDP for GTP on the alpha subunit of the G-protein. This activation of the G-protein triggers downstream signaling pathways, influencing various cellular responses.

Market Dynamics:

The G-protein coupled receptors (GPCR) market is driven by rising incidence of chronic diseases such as cancer and cardiovascular diseases globally. GPCRs play a key role in these conditions and are actively pursued as drug targets. Furthermore, increasing pharmaceutical research and development (R&D) expenditures, availability of advanced screening technologies for GPCR drug discovery, and growing clinical pipeline of GPCR-targeted candidates are fueling market opportunities. However, high costs that are associated with GPCR drug development and commercialization hamper faster market growth. Complex signaling pathways downstream of GPCR activation also pose challenges. Industry players are investing in overcoming technical roadblocks to fully leverage potential of GPCRs as therapeutic targets

Key features of the study:

This report provides in-depth analysis of the global G-protein coupled receptors market, and provides market size (US$ Bn) and compound annual growth rate (CAGR %) for the forecast period (2023-2030), considering 2022 as the base year
It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
It profiles key players in the global G-protein coupled receptors market based on the following parameters - company highlights, products portfolio, key highlights, financial performance, and strategies
Key companies covered as a part of this study Thermo Fisher Scientific Inc., Eurofins Scientific, QIAGEN, WuXi AppTec, Promega Corporation, Abcam plc, Merck KGaA, PerkinElmer Inc., Enzo Biochem Inc., and BD.
Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
Global G-protein coupled receptors market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global G-protein coupled receptors market

Detailed Segmentation:

Global G-Protein Coupled Receptors Market, By Product
- Cell Lines
- Detection Kits
- Cell Culture Reagents
- Ligands
Global G-Protein Coupled Receptors Market, By Assay Type
- cAMP Functional Assays
- Calcium Functional Assays
- β-Arrestin Functional Assays
- Radioligand Binding & GTPγS Functional Assays
- Internalization Assays
- Trafficking Assays
- Other Assays
Global G-Protein Coupled Receptors Market, By Application
- Cancer Research
- CNS Research
- Metabolic Research
- Cardiovascular Research
- Respiratory Research
- Inflammation Research
- Other Applications
Global G-Protein Coupled Receptors Market, By Region
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East
- Africa
Top Companies in the Global G-Protein Coupled Receptors Market:
- Thermo Fisher Scientific Inc.
- Eurofins Scientific
- QIAGEN
- WuXi AppTec
- Promega Corporation
- Abcam plc
- Merck KGaA
- PerkinElmer Inc.
- Enzo Biochem Inc.

1. Research Objectives and Assumptions

Research Objectives
Assumptions
Abbreviations

2. Market Purview

Report Description
- Market Definition and Scope
Executive Summary
- Global G-Protein Coupled Receptors Market, By Product
- Global G-Protein Coupled Receptors Market, By Assay Type
- Global G-Protein Coupled Receptors Market, By Application
- Global G-Protein Coupled Receptors Market, By Region
Coherent Opportunity Map (COM)

3. Market Dynamics, Regulations, and Trends Analysis

Market Dynamics
- Increasing R&D investment by pharmaceutical companies
- Increasing prevalence of chronic diseases
- Technological advancements in GPCR assays
Key Highlights
Regulatory Scenario
Recent Trends
PEST Analysis
PORTER's Analysis
Mergers, Acquisitions, and Collaborations

4. Global G-Protein Coupled Receptors Market- Impact of Coronavirus (COVID-19) Pandemic

COVID-19 Epidemiology
Supply Side and Demand Side Analysis
Economic Impact

5. Global G-Protein Coupled Receptors Market, By Product, 2018-2030, (US$ Bn)

Introduction
- Market Share Analysis, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, 2019 - 2030
- Segment Trends
Cell Lines
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Detection Kits
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Cell Culture Reagents
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Ligands
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)

6. Global G-Protein Coupled Receptors Market, By Assay Type, 2018-2030, (US$ Bn)

Introduction
- Market Share Analysis, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, 2019 - 2030
- Segment Trends
cAMP Functional Assays
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Calcium Functional Assays
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
β-Arrestin Functional Assays
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Radioligand Binding & GTPγS Functional Assays
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Internalization Assays
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Trafficking Assays
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Other Assays
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)

7. Global G-Protein Coupled Receptors Market, By Application, 2018-2030, (US$ Bn)

Introduction
- Market Share Analysis, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, 2019 - 2030
- Segment Trends
Cancer Research
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
CNS Research
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Metabolic Research
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Cardiovascular Research
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Respiratory Research
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Inflammation Research
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Other Applications
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)

8. Global G-Protein Coupled Receptors Market, By Region, 2018-2030, (US$ Bn)

Introduction
- Market Share Analysis, By Region, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, For Region, 2019 -2030
- Country Trends
North America
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Product, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Assay Type, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
U.S.
Canada
Europe
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Product, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Assay Type, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
Germany
U.K.
Spain
France
Italy
Russia
Rest of Europe
Asia Pacific
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Product, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Assay Type, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
China
India
Japan
Australia
South Korea
ASEAN
Rest of Asia Pacific
Latin America
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Product, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Assay Type, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
Brazil
Argentina
Mexico
Rest of Latin America
Middle East
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Product, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Assay Type, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
GCC Countries
Israel
Rest of Middle East
Africa
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Product, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Assay Type, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country/Region, 2018-2030,(US$ Bn)
North Africa
Central Africa
South Africa