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基因治療學和RNAi

市場調查報告書

商品編碼

1424420

反義和 RNAi 療法的全球市場：按技術、按應用、按給藥途徑、按地區

Global Antisense & RNAi Therapeutics Market, By Technology, By Application, By Route of Administration, By Geography

出版日期: 2024年01月12日 | 出版商:

Coherent Market Insights | 英文 175 Pages | 商品交期: 2-3個工作天內

價格

簡介目錄

反義和 RNAi 療法的市場規模預計將從 2023 年的 54 億美元增加到 2030 年的 146.6 億美元，預測期內複合年成長率為 15.3%。

報告範圍		報告詳情
基準年	2022年	2023/2024年市場規模	54億美元
實際資料	2018-2021	預測期	2023-2030
預測期間 2023/2024 至 2030/2031 年複合年成長率：	15.30%	2030/2031價值預測	146.6億美元

圖 1. 2023 年反義和 RNAi 療法的全球市場佔有率（按地區分類）

反義和 RNAi 療法是指利用自然發生的過程來靶向和抑制特定基因表現的一類藥物。這些藥物透過與 mRNA 和基因組 DNA 高度特異性結合而發揮作用。這抑制了疾病相關蛋白的表達。反義和 RNAi 療法市場由於其具有高特異性和較少副作用治療各種疾病的潛力而正在顯著成長。這包括病毒感染、癌症和遺傳性疾病。隨著許多候選藥物透過臨床試驗取得進展，市場正見證大量的研發投資。此外，新的藥物遞送技術的發展擴大了反義和RNAi治療藥物的可能性，並有望應用於以前無法治療的疾病。

市場動態：

反義和RNAi療法是新型的基於核酸的療法，旨在抑制致病基因的表達。它透過與 mRNA 轉錄物結合並抑制翻譯或誘導 mRNA 分解來發揮作用。因此，選擇性定序不必要的基因有望治療各種遺傳性疾病、癌症和病毒感染疾病。此技術利用短的合成核酸鏈，例如 DNA、RNA 或與目標 mRNA 互補的修飾版本。全球反義和 RNAi 治療市場是由各種癌症、遺傳性疾病和感染疾病在全球日益流行所推動的。 RNA標靶藥物在多種疾病的臨床試驗中已被證明是安全有效的，推動了市場成長。此外，核苷酸藥物遞送系統（例如奈米顆粒）的不斷進步正在促進這些治療藥物的細胞攝取並擴大其臨床應用。然而，不斷上升的研發成本以及與藥物開發相關的潛在脫靶效應是市場相關人員面臨的一些挑戰。另一方面，隨著各大品牌專利到期的臨近，學名藥或許還有出現的機會。此外，針對慢性疾病的新型RNAi藥物平台的市場開拓預計將進一步刺激市場擴張。

本研究的主要特點

本報告對全球反義和RNAi治療市場進行了詳細分析，並列出了以2022年為基準年的預測期（2023-2030）的市場規模和複合年成長率。
它揭示了各個細分市場的潛在商機，並概述了該市場有吸引力的投資提案矩陣。
它還提供了有關市場促進因素、限制因素、機會、新產品發布和核准、市場趨勢、區域前景、主要企業採取的競爭策略等的重要考察。
根據公司亮點、產品系列、主要亮點、績效和策略等參數對全球反義和 RNAi 治療市場的主要企業進行了分析。
這些公司從事受管制物質的研發、製造和分銷。
該報告的見解使行銷人員和公司負責人能夠就未來的產品發布、產品升級、市場擴張和行銷策略做出明智的決策。
全球反義和 RNAi 治療市場報告針對該行業的各個相關人員，如投資者、供應商、產品製造商、分銷商、新進業者和財務分析師。
透過用於分析全球反義和 RNAi 治療市場的各種策略矩陣，將促進相關人員的決策。

北美洲
美國
加拿大
歐洲
德國
英國
西班牙
法國
義大利
俄羅斯
其他歐洲國家
亞太地區
中國
印度
日本
澳洲
韓國
ASEAN
其他亞太地區
拉丁美洲
巴西
阿根廷
墨西哥
其他拉丁美洲
中東
海灣合作理事會國家
以色列
其他中東地區
非洲
南非
北非
中部非洲

第9章競爭形勢

Benitec Biopharma Inc.
Silence Therapeutics
Ionis Pharmaceuticals, Inc
Bio-Path Holdings Inc.
Percheron Therapeutics Limited
GSK plc
Olix Pharmaceuticals, Inc.
Sanofi
Alnylam Pharmaceuticals, Inc.
Arbutus Biopharma

第10章

調查方法
關於出版商

簡介目錄

Product Code: CMI6545

The antisense & RNAi therapeutics market size is expected to reach US$ 14.66 Billion by 2030, from US$ 5.40 Billion in 2023, at a CAGR of 15.3% during the forecast period.

Report Coverage		Report Details
Base Year:	2022	Market Size in 2023/2024:	US$ 5.40 Bn
Historical Data for:	2018 to 2021	Forecast Period:	2023 - 2030
Forecast Period 2023/2024 to 2030/2031 CAGR:	15.30%	2030/2031 Value Projection:	US$ 14.66 Bn

Figure 1. Global Antisense & RNAi Therapeutics Market Share (%), by Region, 2023

Global Antisense & RNAi Therapeutics Market - IMG1

Antisense & RNAi therapeutics refer to a class of drugs that use naturally occurring processes to target and inhibit the expression of specific genes. They work by binding to mRNA or genomic DNA with high specificity. This inhibits the expression of disease-associated proteins. The antisense & RNAi therapeutics market is growing substantially due to its potential to treat various conditions with high specificity and few side effects. These include viral infections, cancers, genetic disorders, and others. The market is witnessing significant investments in R&D as many drug candidates are progressing through clinical trials. The development of novel drug delivery techniques is also extending the potential of antisense & RNAi therapeutics to target previously undruggable diseases.

Market Dynamics:

Antisense and RNAi therapeutics are novel nucleic acid-based therapeutics designed to inhibit the expression of disease-causing genes. They work by binding to mRNA transcripts, preventing translation, or inducing mRNA degradation. This offers promise for treating various genetic disorders, cancers, and viral infections by selectively silencing unwanted genes. The technology utilizes short synthetic strands of nucleic acids such as DNA, RNA, or modified versions that are complementary to the target mRNA. The global antisense & RNAi therapeutics market is driven by the growing prevalence of various cancers, genetic disorders, and infectious diseases worldwide. RNA-targeting drugs have demonstrated safety and efficacy in clinical trials for various conditions, boosting market growth. Moreover, continuous advancements in nucleotide drug delivery systems, such as nanoparticles, have enhanced intracellular uptake of these therapeutics, expanding their clinical applications. However, high research and development costs associated with drug development and potential off-target effects are some of the challenges faced by market players. Meanwhile, the upcoming patent expiries of major brands will provide opportunities for generic versions. In addition, the development of novel RNAi drug platforms targeting chronic diseases will further stimulate market expansion.

Key features of the study:

This report provides in-depth analysis of the global antisense & RNAi therapeutics market, and provides market size (US$ Billion) and compound annual growth rate (CAGR%) for the forecast period (2023-2030), considering 2022 as the base year
It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
It profiles key players in the global antisense & RNAi therapeutics market based on the following parameters - company highlights, products portfolio, key highlights, financial performance, and strategies
Key companies covered as a part of this study include Benitec Biopharma Inc., Silence Therapeutics, Ionis Pharmaceuticals, Inc, Bio-Path Holdings Inc., Percheron Therapeutics Limited, GSK plc, Olix Pharmaceuticals, Inc., Sanofi, Alnylam Pharmaceuticals, Inc. and Arbutus Biopharma.
These companies are involved in the research, development, manufacturing, and distribution of controlled substances
Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
The global antisense & RNAi therapeutics market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global antisense & RNAi therapeutics market

Detailed Segmentation:

By Technology:
- RNA Interference
- Antisense RNA
By Application:
- Genetic Disease
- Cancer
- Infectious Disease
- Neurodegenerative Disorders
- Cardio Metabolic & Renal Disorders
- Ocular Disorders
- Respiratory Disorders
- Skin Disorders
- Others
By Route of Administration:
- Intravenous Injections
- Intrathecal Injections
- Subcutaneous Injections
- Others
By Region:
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East
- Africa
Top companies in Antisense & RNAi Therapeutics Market
- Benitec Biopharma Inc.
- Silence Therapeutics
- Ionis Pharmaceuticals, Inc
- Bio-Path Holdings Inc.
- Percheron Therapeutics Limited
- GSK plc
- Olix Pharmaceuticals, Inc.
- Sanofi
- Alnylam Pharmaceuticals, Inc.
- Arbutus Biopharma

1. Research Objectives and Assumptions

Research Objectives
Assumptions
Abbreviations

2. Market Purview

Report Description
- Market Definition and Scope
Executive Summary
- Market Snippet, By Technology
- Market Snippet, By Application
- Market Snippet, By Route of Administration
- Market Snippet, By Region
Coherent Opportunity Map (COM)

3. Market Dynamics, Regulations, and Trends Analysis

Market Dynamics
- Drivers
Promising Innovations in Drug Delivery Systems
- Restraints
High Manufacturing Cost of RNA Therapeutics
- Opportunities
Untapped Emerging Markets
Impact Analysis
Key Highlights
Regulatory Scenario
Product launch/Approvals
PEST Analysis
PORTER's Analysis
Merger and Acquisition Scenario

4. Antisense & RNAi Therapeutics Market - Impact of Coronavirus (COVID-19) Pandemic

COVID-19 Epidemiology
Economic Impact

5. Antisense & RNAi Therapeutics Market , By Technology, 2018-2030, (US$ Bn)

Introduction
- Market Share Analysis, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, 2019 - 2030
- Segment Trends
RNA Interference
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)
Antisense RNA
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Bn)

6. Antisense & RNAi Therapeutics Market , By Application, 2018-2030, (US$ Bn)

Introduction
- Market Share Analysis, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, 2019- 2030
- Segment Trends
Genetic Disease
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Cancer
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Infectious Disease
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Neurodegenerative Disorders
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Cardio Metabolic & Renal Disorders
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Ocular Disorders
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Respiratory Disorders
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Skin Disorders
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Others
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)

7. Antisense & RNAi Therapeutics Market , By Route of Administration, 2018-2030, (US$ Bn)

Introduction
- Market Share Analysis, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, 2019- 2030
- Segment Trends
Intravenous Injections
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Intrathecal Injections
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Subcutaneous Injections
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)
Others
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2018-2030,(US$ Billion)

8. Antisense & RNAi Therapeutics Market , By Region, 2018-2030, (US$ Bn)

Introduction
- Market Share Analysis, By Country, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, For Country 2019-2030
- Country Trends
North America
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Technology, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
U.S.
Canada
Europe
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Technology, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
Germany
U.K.
Spain
France
Italy
Russia
Rest of Europe
Asia Pacific
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Technology, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
China
India
Japan
Australia
South Korea
ASEAN
Rest of Asia Pacific
Latin America
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Technology, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
Brazil
Argentina
Mexico
Rest of Latin America
Middle East
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Technology, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2018-2030,(US$ Bn)
GCC Countries
Israel
Rest of Middle East
Africa
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Technology, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Application, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2018-2030,(US$ Bn)
- Market Size and Forecast, and Y-o-Y Growth, By Country/Region , 2018-2030,(US$ Bn)
South Africa
North Africa
Central Africa

9. Competitive Landscape

Benitec Biopharma Inc.
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
Silence Therapeutics
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Ionis Pharmaceuticals, Inc
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Bio-Path Holdings Inc.
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Percheron Therapeutics Limited
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
GSK plc
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Olix Pharmaceuticals, Inc.
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Sanofi
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Alnylam Pharmaceuticals, Inc.
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Arbutus Biopharma
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Strategies
Analyst Views