市場調查報告書
商品編碼
1468024
數位 PCR 和即時PCR市場:按類型、產品類型、應用和最終用戶 - 2024-2030 年全球預測Digital PCR & Real-Time PCR Market by Type (dPCR, qPCR), Product Type (Instruments, Reagents & Consumables, Services), Application, End-User - Global Forecast 2024-2030 |
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數位PCR和即時PCR市場規模預計到2023年為82.4億美元,2024年達到88.7億美元,預計2030年將達到141.1億美元,複合年成長率為7.98%。
數位 PCR (dPCR) 和即時PCR,通常稱為定量 PCR (qPCR),是聚合酵素鏈鎖反應(PCR) 科學廣泛領域中體現的兩項關鍵技術。數位 PCR (dPCR) 是一種用於絕對定量核酸的先進分子生物學技術,涉及將樣本細分為許多包含 0 或 1 個模板分子的單獨小反應。即時PCR,也稱為定量PCR(qPCR),與標準PCR的不同之處在於可以即時檢測擴增產物反應的累積。由於這些技術在檢測低水平病原體和稀有基因序列方面具有高精度和敏感性,因此需求量很大。對早期準確診斷的需求迅速增加,遺傳疾病和感染疾病的擴散正在導致數位 PCR 和即時PCR市場的成長。此外,COVID-19 大流行特別凸顯了基於 PCR 的診斷在管理感染疾病爆發方面的關鍵作用。儘管數位 PCR 和即時PCR市場不斷成長,但仍面臨一些限制,例如液滴大小和型態的變化,這影響了方法的穩健性,以及新興經濟體對專業知識的需求。然而,市場參與企業對研發的投資不斷增加,以及提供高精度和靈敏度的液滴數位 PCR (ddPCR) 技術的出現,為數位 PCR 和即時PCR市場的成長帶來了前景。
主要市場統計 | |
---|---|
基準年[2023] | 82.4億美元 |
預測年份 [2024] | 88.7億美元 |
預測年份 [2030] | 141.1億美元 |
複合年成長率(%) | 7.98% |
qPCR 的高通量和寬動態範圍日益偏好
數位 PCR 透過將樣本分為數千個單獨的反應,每個反應包含零個、一個或幾個模板分子,從而可以對核酸進行絕對定量。 PCR 後,對含有擴增 DNA 的分區進行計數,描述直接、準確的定量,無需標準曲線或參考樣本。即時PCR,通常稱為定量 PCR 或 qPCR,是分子生物學中廣泛使用的技術,可擴增並同時定量目標 DNA 分子。 qPCR 的一個關鍵特徵是使用螢光染料或探針。螢光染料或探針與 DNA 結合,可以隨著反應的進行定量。
產品類型:對專用套件的需求不斷增加,以滿足專業最終用戶的需求
在數位 PCR 和即時PCR市場中,設備是研究人員為各種應用擴增 DNA 和 RNA 的必備產品。樣品分裂系統用於將樣品分裂成數千個獨立的小液滴。另一方面,聚合酵素連鎖反應熱迴圈儀用於透過聚合酵素鏈鎖反應擴增部分樣品,封板機用於密封PCR板,以盡量減少擴增過程中樣品的蒸發。試劑和耗材是數位 PCR 和即時PCR技術的重要組成部分,包括這些工作流程中使用的所有必要化學品和一次性材料。這包括用於 dPCR 和 qPCR 應用的各種酵素、引子、緩衝液和預混液。這些試劑的品質直接影響 dPCR 和 qPCR 技術的準確性、靈敏度和重現性。同樣,PCR 管、板和密封等耗材的設計可確保與各種 dPCR 和 qPCR 儀器相容,同時防止日常業務所必需的交叉污染和樣品損失。數位 PCR 和即時PCR市場得到了從開發到驗證和樣本測試的一系列服務的補充,可滿足客戶的多樣化需求。外包 dPCR 和 qPCR 服務使最終用戶能夠最大限度地降低實驗室設置的前期成本,同時促進經過認證的專業服務供應商開發客製化解決方案。
應用:在法醫學方面具有巨大潛力,例如親子鑑定和犯罪現場調查中低水平 DNA 的檢測
在臨床研究領域,數位 PCR (dPCR) 和即時PCR(qPCR) 在促進疾病理解和治療方面發揮重要作用。這些技術因其高精度和強大功能而被專門採用,使其可用於檢測罕見突變和拷貝數變異以及監測微小殘留疾病。此外,快速可靠的基因表現定量可以幫助疾病分層、監測治療效果以及檢驗疾病進展和治療反應的生物標記。法醫實驗室嚴重依賴 qPCR 的特異性和靈敏度來進行 DNA 分析、檢測微量遺傳物質以及在序列測定前對 DNA 進行定量。 dPCR 和 qPCR 的出現進一步完善了法醫分析,增強了低水平病原體的檢測和混合 DNA 樣本的分析。在研究實驗室中,dPCR 和 qPCR 是基因組、功能基因體學和分子生物學研究的重要工具。這些技術對於檢驗次世代定序儀的結果、研究基因編輯的結果以及探索病毒感染和微生物定量的動態至關重要。
最終使用者:dPCR 和 qPCR 在個人化藥物開發中的重要應用
數位PCR和即時PCR方法在定量基因表現分析、定序結果檢驗和單細胞分析方面具有高精度和準確性,在學術研究中發揮至關重要的作用。 dPCR 提供的資料粒度對於檢測稀有等位基因和了解單分子水平的變異特別有用,而 qPCR 的快速即時資料功能使其可用於快速實驗複製和教育應用。在農業和生命科學領域,數位 PCR 和即時PCR是遺傳分析、基因改造作物(GMO) 檢測和病原體鑑定的重要工具。 dPCR 在量化 DNA 變異方面具有無與倫比的靈敏度,這是作物改良計劃中性狀選擇的基礎,而qPCR 用於監測植物和牲畜的疾病爆發,提高農業生產力和生物安全性,因其多功能性和快速通量而被廣泛應用。 CRO和CDMO利用數位PCR和即時PCR技術為藥物開發提供生物標記發現、臨床試驗支援和品管等專業服務。醫院和診斷實驗室依靠即時PCR提供的快速、準確的診斷來檢測感染疾病、遺傳疾病和癌症生物標記。在臨床環境中,qPCR 的輕鬆整合和快速週轉時間對於患者管理決策至關重要。數位 PCR 和即時PCR在藥物和生物製藥研發中對於藥物發現驗證、藥物基因體學和製造過程中的品管至關重要。 dPCR 的高解析度對於低豐度標靶的準確定量以及評估可能影響藥物功效或安全性的基因表現的微小變化特別有用。 qPCR 的適應性為藥物發現和藥物開發中的高通量篩檢和驗證提供了可靠的方法,從而簡化了藥物研發流程。
區域洞察
強大的生物技術和製藥行業、政府對醫學研究的大力投資以及技術先進的診斷技術的廣泛採用正在推動美洲數位 PCR 的成長,即時PCR市場也呈現強勁成長。由於需要先進的能力來對抗感染疾病、遺傳疾病和各種癌症的傳播,歐洲數位 PCR 和即時PCR市場正在穩步成長。先進的醫療基礎設施和生物技術領域研發活動的大量投資正在支持該地區的市場擴張。中東和非洲地區的成長是由醫療設施改善、經濟發展和創新診斷技術的普及所推動的。亞太地區是 dPCR 和 qPCR 技術成長最快的區域市場。這一成長主要歸功於中國、日本、印度、韓國和澳洲等國家生物醫藥產業的擴張。由於該地區人口眾多,對包括 dPCR 和 qPCR 在內的先進診斷方法有很高的需求。政府在醫療保健方面的支出增加和慢性病盛行率的上升進一步推動了該地區的市場成長。
FPNV定位矩陣
FPNV定位矩陣對於評估數位PCR和即時PCR市場至關重要。我們檢視與業務策略和產品滿意度相關的關鍵指標,以對供應商進行全面評估。這種深入的分析使用戶能夠根據自己的要求做出明智的決策。根據評估,供應商被分為四個成功程度不同的像限。最前線 (F)、探路者 (P)、利基 (N) 和重要 (V)。
市場佔有率分析
市場佔有率分析是一種綜合工具,可對數位 PCR 和即時PCR市場供應商的現狀進行深入而深入的研究。全面比較和分析供應商在整體收益、基本客群和其他關鍵指標方面的貢獻,以便更好地了解公司的績效及其在爭奪市場佔有率時面臨的挑戰。此外,該分析還提供了對該細分市場競爭特徵的寶貴見解,包括在研究基準年觀察到的累積、碎片化主導地位和合併特徵等因素。這種詳細程度的提高使供應商能夠做出更明智的決策並制定有效的策略,從而在市場上獲得競爭優勢。
1. 市場滲透率:提供有關主要企業所服務的市場的全面資訊。
2. 市場開拓:我們深入研究利潤豐厚的新興市場,並分析其在成熟細分市場的滲透率。
3. 市場多元化:包括新產品發布、開拓地區、最新發展和投資的詳細資訊。
4.競爭力評估及資訊:對主要企業的市場佔有率、策略、產品、認證、監管狀況、專利狀況、製造能力等進行全面評估。
5. 產品開發與創新:包括對未來技術、研發活動和突破性產品開發的智力見解。
1. 數位PCR和即時PCR市場的市場規模和預測是多少?
2. 在數位PCR和即時PCR市場的預測期內,我們應該考慮投資哪些產品和應用?
3. 數位PCR和即時PCR市場的技術趨勢和法規結構是什麼?
4.數位PCR和即時PCR市場主要廠商的市場佔有率是多少?
5. 進入數位PCR和即時PCR市場的合適型態和策略手段是什麼?
[194 Pages Report] The Digital PCR & Real-Time PCR Market size was estimated at USD 8.24 billion in 2023 and expected to reach USD 8.87 billion in 2024, at a CAGR 7.98% to reach USD 14.11 billion by 2030.
Digital PCR (dPCR) and real-time PCR, often referred to as quantitative PCR (qPCR), are two pivotal techniques bodied under the broader field of polymerase chain reaction (PCR) science. Digital PCR (dPCR) is an advanced molecular biology technique for the absolute quantification of nucleic acids, which includes subdividing the sample into many individual, smaller reactions that contain either zero or one template molecule. Real-Time PCR, known as quantitative PCR (qPCR), differs from standard PCR by enabling the detection of the accumulation of amplification product reaction as it occurs in real-time. These techniques are in high demand owing to their heightened precision and sensitivity for detecting low-level pathogens and rare genetic sequences. The surge in the need for early and precise diagnosis and an uptick in genetic disorders and infectious diseases has led to the growth of the digital PCR & real-time PCR market. Further, the COVID-19 pandemic particularly highlighted the critical role of PCR-based diagnostics in managing infectious outbreaks. Despite its growth, the digital PCR & real-time PCR market contend with limitations, including the variability in the size and shape of droplets, which affect the robustness of the method and the need for specialized expertise in developing economies. However, growing investments by industry participants in R&D and the emergence of droplet digital PCR (ddPCR) technology for exquisite precision and sensitivity promise future prospects for the digital PCR & real-time PCR market growth.
KEY MARKET STATISTICS | |
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Base Year [2023] | USD 8.24 billion |
Estimated Year [2024] | USD 8.87 billion |
Forecast Year [2030] | USD 14.11 billion |
CAGR (%) | 7.98% |
Type: Higher preferences for qPCR for high throughput and a broader dynamic range
Digital PCR allows absolute quantification of nucleic acids by partitioning the sample into thousands of separate reactions, with each containing zero, one, or a few template molecules. Post PCR, the number of partitions containing amplified DNA is counted, providing direct and precise quantification without the need for standard curves or reference samples. Real-time PCR, often referred to as quantitative PCR or qPCR, is a technology widely used in molecular biology to amplify and simultaneously quantify a targeted DNA molecule. A key feature of qPCR is the use of fluorescent dyes or probes, which bind to the DNA and allow quantification as the reaction progresses.
Product Type: Growing demand for application-specific kits that address the needs of specialized end-users
Within the digital PCR & real-time PCR market, instruments are the vital products that enable researchers to amplify DNA and RNA for various applications. Sample partitioning systems are used to divide the sample into thousands of separate, small droplets. Whereas, thermal cyclers are deployed to amplify segments of the sample via the polymerase chain reaction, and plate sealers are used to seal PCR plates to minimize sample evaporation during amplification. Reagents and consumables represent a critical segment of digital PCR & real-time PCR technologies, encompassing all necessary chemicals and disposable materials used in these workflows. This includes a variety of enzymes, primers, buffers, and master mixes tailored for dPCR and qPCR applications. The quality of these reagents directly impacts the accuracy, sensitivity, and repeatability of dPCR and qPCR techniques. Likewise, the consumables, such as PCR tubes, plates, and seals, are designed to ensure compatibility with different dPCR and qPCR instruments while preventing cross-contamination and sample loss and are essential for the day-to-day operation of any laboratory engaged in molecular testing. The digital PCR & real-time PCR market is complemented by an array of services that cater to customers' diverse needs, from development, validation, and sample testing. Outsourcing dPCR and qPCR services minimizes upfront costs of laboratory setup for end-users while facilitating the development of customized solutions from authorized and expert service providers.
Application: Higher potential in forensics for paternity testing and the detection of low-level DNA in crime scene investigations
In the realm of clinical research, both digital PCR (dPCR) and real-time PCR (qPCR) serve critical roles in advancing our understanding and treatment of diseases. These techniques are particularly adopted for their high precision and ability, making them valuable for detecting rare mutations, copy number variations, and monitoring minimal residual disease. Further, their rapid and reliable quantification of gene expression helps with disease stratification, monitoring treatment efficacy, and validating biomarkers for disease progression and therapeutic response. Forensic laboratories rely heavily on the specificity and sensitivity of qPCR for DNA profiling, detecting minute traces of genetic material, and quantifying DNA prior to sequencing. The advent of dPCR and qPCR has further refined forensic analysis, enhancing the detection of low-level pathogens and analysis of mixed DNA samples. At research institutes, dPCR and qPCR are indispensable tools for genomic research, functional genomics, and molecular biology studies. These techniques are crucial for validating findings from next-generation sequencing, studying gene-editing outcomes, and probing the dynamics of viral infections and microbial quantification.
End-User: Significant applications of dPCR & qPCR in the personalized drug development he
Digital PCR and real-time PCR methods are pivotal in academic research for their high precision and accuracy in quantitative gene expression analysis, validation of sequencing results, and single-cell analysis. The granularity of data provided by dPCR is especially valuable for detecting rare alleles and understanding variations at the single-molecule level in scientific studies, while qPCR's rapid real-time data capabilities allow for swift experimental iterations and educational applications. In the agriculture and life sciences sector, digital PCR and real-time PCR are indispensable tools for genetic trait analysis, genetically modified organism (GMO) detection, and pathogen identification. dPCR offers unparalleled sensitivity in quantifying DNA alterations that underpin trait selection in crop improvement programs, while qPCR is widely used for its versatility and rapid throughput in monitoring disease outbreaks in plants and livestock, ensuring agricultural productivity and biosecurity. CROs and CDMOs utilize digital and real-time PCR techniques to offer specialized services, such as biomarker discovery, clinical trial support, and quality control for drug development. Hospitals and diagnostic laboratories rely on the rapid and accurate diagnostics afforded by real-time PCR to detect infectious diseases, genetic disorders, and cancer biomarkers. In the clinical environment, the ease of integration and rapid turnaround time of qPCR are critical for patient management decisions. Digital PCR and real-time PCR are essential in pharmaceutical and biopharmaceutical research and development for drug target validation, pharmacogenomics, and quality control during manufacturing processes. The fine resolution of dPCR is particularly beneficial in the precise quantitation of low-abundance targets and in assessing minor variations in gene expression that may influence drug efficacy and safety. qPCR's adaptability streamlines the pharmaceutical pipeline by offering a robust method for high-throughput screening and validation in drug discovery and development.
Regional Insights
In the Americas, the digital PCR & real-time PCR market is showing robust growth, attributed to the region's strong biotechnology and pharmaceutical sectors, active government investments in healthcare research, and the wide adoption of technologically advanced diagnostic methods. The European market for digital PCR & real-time PCR is witnessing steady growth owing to the need for advanced capabilities to counter the increasing prevalence of infectious diseases, genetic disorders, and various types of cancer. Advanced healthcare infrastructure and significant investments in R&D activities in the biotechnology sector underpin the market expansion in the region. The growth in the Middle East and Africa is propelled by improving healthcare facilities, economic development, and increased access to innovative diagnostic technologies. The Asia-Pacific is emerging as the fastest-growing regional market for dPCR and qPCR technologies. The growth is largely fueled by the expanding biomedical industry in countries such as China, Japan, India, South Korea, and Australia. The region's large population base presents a significant demand for advanced diagnostic methods including dPCR and qPCR. Increased government expenditure on healthcare and the rising prevalence of chronic diseases are further catalyzing the market growth in the region.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the Digital PCR & Real-Time PCR Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Digital PCR & Real-Time PCR Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the Digital PCR & Real-Time PCR Market, highlighting leading vendors and their innovative profiles. These include Abbott Laboratories, Inc., Agilent Technologies, Inc., Analytik Jena GmbH+Co. KG, Azure Biosystems Inc., Becton, Dickinson and Company, Bio-Rad Laboratories, Inc., Biocompare by CompareNetworks, Inc., BIOMERIEUX S.A., Bioneer Corporation, Danaher Corporation, ELITech Group, Enzo Life Sciences, Inc., Eppendorf SE, Etcon Analytical and Environmental Systems & Services Ltd., Explorea s.r.o, F. Hoffmann-La Roche AG, Global Engage Sdn. Bhd., Hangzhou Longgene Scientific Instruments Co., Ltd., Heal Force Bio-Meditech Holdings Limited, Integrated DNA Technologies, Inc., LABGENE Scientific SA, Merck KGaA, Meridian Bioscience, Inc., Promega Corporation, QIAGEN N.V., Quidel Corporation, R-Biopharm AG, RainSure Scientific, Roche Diagnostics Corporation, Solis BioDyne OU, STANDARD BIOTOOLS INC., Takara Bio USA, Inc., Thermo Fisher Scientific Inc., and Zymo Research Corp.
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the Digital PCR & Real-Time PCR Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Digital PCR & Real-Time PCR Market?
3. What are the technology trends and regulatory frameworks in the Digital PCR & Real-Time PCR Market?
4. What is the market share of the leading vendors in the Digital PCR & Real-Time PCR Market?
5. Which modes and strategic moves are suitable for entering the Digital PCR & Real-Time PCR Market?
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