市場調查報告書
商品編碼
1464780
抗瘧疾藥市場:按藥物類別、按藥物類型、按途徑、按瘧疾類型、按配銷通路、按最終用戶 - 2024-2030 年全球預測Antimalarial Drugs Market by Drug Class (Antifolate compounds, Artemisinin compounds, Aryl aminoalcohol compounds), Drug Type (Branded, Generic), Route of Administration, Malaria Type, Distribution Channel, End User - Global Forecast 2024-2030 |
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預計2023年抗瘧疾藥市場規模為16.7億美元,預計2024年將達17.6億美元,2030年將達25億美元,複合年成長率為5.88%。
抗瘧疾藥是用於預防和治療瘧疾的藥物化合物,瘧疾是一種透過受感染的瘧蚊叮咬傳播的危及生命的疾病。這些藥物針對引起瘧疾的瘧疾原蟲生命週期的各個階段,有效減少瘧疾傳播並緩解受影響者的症狀。抗瘧疾藥的效用涵蓋多種情況,從旅行者到流行地區的預防性使用,到診斷病例的治療性介入。這些藥物的開發和部署對於控制、根除和根除瘧疾的全球衛生工作至關重要,特別是在瘧疾流行率最高的熱帶和亞熱帶地區。全球瘧疾盛行率不斷上升以及世界衛生組織對瘧疾根除計畫的支持不斷增加,正在推動抗瘧疾藥市場的成長。然而,抗藥性瘧疾菌株的出現正在阻礙抗瘧疾藥市場的擴大。抗瘧疾藥領域藥物開發和診斷測試的創新為市場提供了利潤豐厚的成長機會。
主要市場統計 | |
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基準年[2023] | 16.7億美元 |
預測年份 [2024] | 17.6億美元 |
預測年份 [2030] | 25億美元 |
複合年成長率(%) | 5.88% |
由於有效的結果,按藥物類別擴大了青蒿素化合物的使用
乙胺嘧啶和磺胺多辛等抗葉酸化合物可有效抑制瘧疾瘧疾原蟲體內的葉酸合成,而葉酸對於瘧疾原蟲中核酸和蛋白質的產生至關重要。這些化合物通常聯合使用以提高功效並防止抗藥性。基於青蒿素的聯合治療(ACT)是現代瘧疾治療的基石,為降低全球瘧疾死亡率做出了重大貢獻。青蒿素及其衍生物青蒿酯、蒿甲醚和青蒿素源自植物蒿,對瘧疾原蟲起效快且高效。胺基化合物包括奎寧、甲氟喹和鹵泛群,它們主要對紅血球階段的寄生蟲有效。儘管它們已經使用了很長時間,但由於抗藥性細菌的發展和副作用,它們的使用受到限制並被更新的藥物所取代。內過氧化物在某些情況下是必不可少的,特別是在治療多重抗藥性瘧疾菌株時。內過氧化物是為對抗青蒿素抗藥性而開發的新藥。這些化合物,例如 Ozonide OZ439(artefenomel),保留了抗瘧活性所需的關鍵過氧化物橋,並透過正在進行的臨床試驗提供了作為抗瘧治療方法的廣闊前景。喹啉-甲醇抗瘧疾藥,包括甲氟喹和本芴醇,可有效對抗抗藥性惡性瘧原蟲。這些抗瘧疾藥的作用機制涉及抑制寄生蟲內的血紅蛋白消化。四環黴素抗生素,如多西環素,是頻譜抗生素,用作瘧疾聯合聯合治療的一部分,特別用於在有抗藥性寄生蟲的地區進行治療和預防。由於其安全性和成本效益,四環黴素抗生素繼續在某些治療環境中穩定使用。
瘧疾類型:瘧疾原蟲增加
瘧疾原蟲是最危險的瘧疾原蟲之一,常導致嚴重的瘧疾。這類瘧疾致病性高,進展迅速,因此治療需要速效抗瘧疾藥。全世界推薦以青蒿素為基礎的聯合療法(ACT)用於治療惡性瘧原蟲瘧疾。這包括蒿甲醚-本芴醇和青蒿琥酯-阿莫地喹等組合。在 ACT 抗藥性的地區,可以使用奎寧加多西環素或克林黴素方案。對於嚴重的瘧疾病例,建議靜脈注射青蒿琥酯。諾氏瘧原蟲最初被認為會感染猴子,現在已成為東南亞人類瘧疾的重要原因。治療策略與瘧疾原蟲相似,因為這種瘧疾原蟲的生命週期很快,可以導致嚴重的瘧疾。以青蒿素為基礎的聯合治療(ACT)是有效的。瘧疾原蟲通常沒有瘧疾原蟲那麼嚴重。Chloroquine通常足以治療瘧疾原蟲。如果不擔心Chloroquine抗藥性,這種藥物因其有效且成本低廉而成為首選藥物。卵形瘧疾原蟲與間日瘧原蟲一樣,會導致肝臟休眠期的瘧疾復發。奧巴雷寄生蟲的治療包括用於血液階段感染的Chloroquine和用於消除休眠肝臟階段感染並防止復發的伯氨喹。這種雙管齊下的方法可確保清除血液和肝臟中的寄生蟲並防止復發。已知瘧疾原蟲會經由肝臟中的休眠子引起瘧疾復發。治療包括用於血期感染的Chloroquine和用於肝期感染的伯氨喹。一種新的替代藥物他非諾喹具有與伯氨喹類似的作用,但需要篩檢G6PD 缺乏症。
區域洞察
在北美和南美洲,抗瘧疾藥正在引起人們的關注,特別是在瘧疾病例持續存在的國家,如巴西、哥倫比亞、秘魯以及中美洲和加勒比地區的部分地區。市場動態的特徵是政府積極干預,例如消除瘧疾的努力和資金。亞太地區的抗瘧疾藥市場高度多樣化,因為印度、中國和印尼等國家的瘧疾盛行率和醫療基礎設施各不相同。高危險群、有利於蚊子繁殖的氣候條件、社會經濟差異等因素都會影響市場。根除和控制瘧疾的努力正在加強,各國政府和國際組織對醫療保健系統的大量投資正在推動抗瘧疾藥的需求。假藥和抗藥性問題仍然是一個重大問題。在歐洲,嚴格的監管標準和高度的瘧疾預防意識指南消費者的購買行為。歐盟最近的研究和開發重點是疫苗開發和新型抗瘧化合物的發現。 EMEA(歐洲、中東和非洲)地區表現出與瘧疾患者眾多的非洲不同的市場特徵。由於青蒿素聯合治療(ACT)等藥物的普及,撒哈拉以南非洲地區對抗瘧疾藥的需求仍然很高。在中東,患病率各不相同。根除和控制瘧疾(特別是在非洲)的努力預計將推動歐洲、中東和非洲地區的抗瘧疾藥市場。
FPNV定位矩陣
FPNV定位矩陣對於評估抗瘧疾藥市場至關重要。我們檢視與業務策略和產品滿意度相關的關鍵指標,以對供應商進行全面評估。這種深入的分析使用戶能夠根據自己的要求做出明智的決策。根據評估,供應商被分為四個成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市場佔有率分析
市場佔有率分析是一種綜合工具,可以對抗瘧疾藥市場供應商的現狀進行深入而詳細的研究。全面比較和分析供應商在整體收益、基本客群和其他關鍵指標方面的貢獻,以便更好地了解公司的績效及其在爭奪市場佔有率時面臨的挑戰。此外,該分析還提供了對該行業競爭特徵的寶貴見解,包括在研究基準年觀察到的累積、分散主導地位和合併特徵等因素。這種詳細程度的提高使供應商能夠做出更明智的決策並制定有效的策略,從而在市場上獲得競爭優勢。
1. 市場滲透率:提供有關主要企業所服務的市場的全面資訊。
2. 市場開拓:我們深入研究利潤豐厚的新興市場,並分析其在成熟細分市場的滲透率。
3. 市場多元化:提供有關新產品發布、開拓地區、最新發展和投資的詳細資訊。
4.競爭評估及資訊:對主要企業的市場佔有率、策略、產品、認證、監管狀況、專利狀況、製造能力等進行綜合評估。
5. 產品開發與創新:提供對未來技術、研發活動和突破性產品開發的見解。
1.抗瘧疾藥市場規模及預測是多少?
2.抗瘧疾藥市場預測期間需要考慮投資的產品、細分市場、應用和領域有哪些?
3.抗瘧疾藥市場的技術趨勢和法規結構是什麼?
4.抗瘧疾藥市場主要廠商的市場佔有率是多少?
5. 進入抗瘧疾藥市場的適當型態和策略手段是什麼?
[190 Pages Report] The Antimalarial Drugs Market size was estimated at USD 1.67 billion in 2023 and expected to reach USD 1.76 billion in 2024, at a CAGR 5.88% to reach USD 2.50 billion by 2030.
Antimalarial drugs are pharmaceutical compounds designed to prevent and treat malaria, a life-threatening disease transmitted by an infected Anopheles mosquito bite. These drugs target the different life cycle stages of the Plasmodium parasites responsible for malaria, effectively reducing the disease's transmission and alleviating the symptoms in affected individuals. Antimalarial drugs' utility spans various contexts, from prophylactic usage in travelers to endemic regions to therapeutic interventions in diagnosed cases. The development and deployment of these medications are critical in global health efforts aimed at controlling, eliminating, and eradicating malaria, particularly in tropical and subtropical regions where the disease prevalence is highest. Rising incidence rates of malaria globally and the increasing support from global health organizations for malaria eradication programs are driving the growth of the antimalarial drugs market. However, the emergence of drug-resistant malaria strains is hindering the expanding antimalarial drugs market. Innovations in drug development and diagnostic tests in the area of antimalarial drugs offer lucrative growth opportunities for the market.
KEY MARKET STATISTICS | |
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Base Year [2023] | USD 1.67 billion |
Estimated Year [2024] | USD 1.76 billion |
Forecast Year [2030] | USD 2.50 billion |
CAGR (%) | 5.88% |
Drug Class: Widening use of artemisinin compounds owing to its effective results
Antifolate compounds, such as pyrimethamine and sulfadoxine, work by inhibiting folate synthesis within the malaria parasite, essential for its nucleic acid and protein production. These compounds are often combined to enhance their efficacy and prevent resistance. Artemisinin-based combination therapies (ACTs) are the cornerstone of modern malaria treatment and have significantly contributed to the reduction in malaria mortality rates worldwide. Derived from the plant Artemisia annua, artemisinin and its derivatives, such as artesunate, artemether, and dihydroartemisinin, are fast-acting and highly effective against Plasmodium falciparum. Aryl aminoalcohol compounds include quinine, mefloquine, and halofantrine, which are primarily effective against the erythrocytic stages of Plasmodium parasites. Despite their long history of use, the development of resistance and side effects have limited their use in favor of newer medications. They remain essential in certain contexts, particularly for treating multidrug-resistant strains of malaria. Endoperoxides include new developments designed to combat artemisinin resistance. These compounds, such as ozonide OZ439 (artefenomel), retain the vital peroxide bridge necessary for their antimalarial activity and offer a promising future for antimalarial treatment modalities with ongoing clinical trials. Quinoline methanol antimalarials, including mefloquine and lumefantrine, are effective against drug-resistant P. falciparum. Their mode of action includes interference with hemoglobin digestion within the parasite. Tetracyclines, such as doxycycline, are broad-spectrum antibiotics used as part of combination therapy for malaria, especially for treatment and prevention in areas with drug-resistant parasites. Due to their safety profile and cost-effectiveness, tetracyclines continue to see steady use in specific therapeutic scenarios.
Malaria Type: Increasing prevalence of plasmodium falciparum
Plasmodium falciparum is dangerous among the malaria parasites, often leading to severe malaria. This type of malaria requires fast-acting antimalarial drugs for treatment due to their high virulence and rapid progression. Artemisinin-based combination therapies (ACTs) are the recommended treatment for P. falciparum malaria worldwide. These include combinations such as artemether-lumefantrine and artesunate-amodiaquine. Other regimens, such as quinine combined with doxycycline or clindamycin, may be used in regions resistant to ACTs. Intravenous artesunate is preferred for severe malaria cases. Plasmodium knowlesi, initially known for infecting macaques, has emerged as a significant cause of human malaria in Southeast Asia. The treatment strategy for P. knowlesi is similar to that for Plasmodium falciparum due to its rapid lifecycle potentially leading to severe malaria. Artemisinin-based combination therapy (ACT) is effective. Plasmodium malariae causes a generally less severe form of malaria than P. falciparum. Chloroquine is typically adequate for treating P. malariae infections. Where chloroquine resistance is not a concern, this drug remains the first choice due to its effectiveness and low cost. Plasmodium ovale causes relapsing malaria due to dormant liver stages, similar to P. vivax. The treatment for P. ovale encompasses chloroquine for the blood-stage infection and a course of primaquine to clear the dormant liver stage and prevent relapse. This two-pronged approach ensures the elimination of the parasite from the bloodstream and the liver to prevent recurrence. Plasmodium vivax is notable for its ability to cause relapsing malaria due to dormant stages in the liver (hypnozoites). Treatment involves the use of chloroquine for the blood-stage infection paired with primaquine to eradicate the liver stage. Tafenoquine, a new alternative, offers similar benefits to primaquine but requires less frequent dosing, although it also requires screening for G6PD deficiency.
Regional Insights
In the Americas, the focus on antimalarial drugs predominantly revolves around countries with persistent malaria cases, such as Brazil, Colombia, and Peru in South America and some parts of Central America and the Caribbean. The market dynamics are characterized by active government intervention, including initiatives and funding to eradicate malaria. The Asia-Pacific region represents a highly diverse antimalarial drugs market due to varying malaria prevalence and healthcare infrastructure across countries such as India, China, and Indonesia. Factors such as a large at-risk population, climatic conditions conducive to mosquito breeding, and socio-economic disparities impact the market. Efforts toward malaria elimination and control have been intensified, with significant investments from governments and international bodies in healthcare systems, boosting the demand for antimalarial drugs. Issues of counterfeit drugs and drug resistance remain critical concerns. Stringent regulatory standards and a high level of awareness regarding malaria prevention guide consumer purchasing behavior in Europe. Recent research initiatives in the EU focus on vaccine development and the discovery of new antimalarial compounds. The EMEA region exhibits different market characteristics, with Africa having high malaria cases. The demand for antimalarial drugs in Sub-Saharan Africa remains high, driven by the prevalent use of drugs such as artemisinin-based combination therapies (ACTs). The Middle East experiences varied prevalence rates. The malaria elimination and control initiatives, especially in Africa, are expected to drive the antimalarial drugs market in the EMEA region.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the Antimalarial Drugs Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Antimalarial Drugs Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the Antimalarial Drugs Market, highlighting leading vendors and their innovative profiles. These include Abbott Laboratories, Alkem Laboratories, Alliance Pharma, Alvizia Health Care, Bayer AG, Cipla Inc., Dr. Reddy's Laboratories, F. Hoffmann-La Roche Ltd., GlaxoSmithKline plc, Glenmark Pharmaceuticals, Hikma Pharmaceuticals PLC, Ipca Laboratories Ltd., Lincoln Pharmaceuticals, Lupin Limited, Merck KGaA, Mylan, Novartis AG, Pfizer Inc., Sanofi Group, Strides Pharma Science Limited, Sun Pharmaceutical Industries Ltd., Takeda Pharmaceutical Company, Teva Pharmaceuticals Industries Ltd., Zydus Group, and Zydus Lifesciences Ltd..
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the Antimalarial Drugs Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Antimalarial Drugs Market?
3. What are the technology trends and regulatory frameworks in the Antimalarial Drugs Market?
4. What is the market share of the leading vendors in the Antimalarial Drugs Market?
5. Which modes and strategic moves are suitable for entering the Antimalarial Drugs Market?