精準發酵的技術成長機會

日益激烈的競爭促進了不同行業高影響力、永續的新原料的出現

傳統發酵長期以來一直被使用，特別是在食品生產中。發酵的應用正在擴展到替代蛋白質和其他成分的生產。傳統發酵利用自然狀態下的微生物生產工業化學品、生物材料、藥品、食品和飲料和飲料以及個人護理產品的生物基成分。或者，在生質能發酵中，培養富含蛋白質的微生物，快速生長的微生物生質能成為替代蛋白質原料。儘管傳統發酵比化學合成更永續、更環保，但這種製程只能生產有限種類的成分。其他缺點包括需要大量原料、產量和純度低、上游加工昂貴且耗時、品質不穩定造成的健康風險以及有毒廢棄物和副產品對環境的負面影響。

精準發酵是製造業的新浪潮，它使用最佳化或基因工程菌株在精確控制的發酵過程中生產成分。各行業的領先公司正在採用精密發酵，以滿足對環保化學品和原料、具有產品增強特性的新原料、安全供應鏈和提高生產力日益成長的需求。本報告的範圍僅限於精密發酵技術在化學品和材料、食品和飲料、製藥和個人護理行業中的應用，這些是對精密發酵影響最大的應用。

合作和策略夥伴關係正在促進該行業的顯著成長。美國和歐洲在精準發酵的創新和採用方面處於領先地位。主要產業參與者正致力於擴大精確發酵原料的生產規模並降低生產成本。值得注意的是，合成生物學新興企業透過原料設計日益影響精準發酵的進步，使該領域成為生物技術公司充滿希望的成長機會。這就是我正在做的事情。人工智慧、機器人和合成生物學技術的進步正在帶來成長機會。

精密發酵可能永遠無法完全取代傳統成分，尤其是在食品和飲料和個人護理行業。然而，隨著各行業對永續原料的需求不斷增加，它們很可能在不久的將來成為主流生產技術，促進各大公司的成長。

本次調查回答的問題

• 精準發酵的產業需求有哪些？什麼是精準發酵及其好處？精密發酵有哪些種類和用途？
• 開發精準發酵技術和實現該技術的技術的主要企業有哪些？
• 精密發酵產業的生長促進因子和成長抑制因素有哪些？
• 精準發酵的產業需求和影響有哪些？區域趨勢是什麼？參與企業有哪些？您將使用什麼技術以及該解決方案的用途是什麼？使用精密發酵的主要公司有哪些？為什麼？您最近有哪些合作夥伴關係和協作活動？精準發酵對應用領域的各種原料有何影響？
• 該行業的資金籌措和智慧財產權 (IP) 活動的趨勢是什麼？
• 精準發酵產業的成長機會有哪些？
• 精準發酵將如何影響各種應用？克服產業關鍵障礙的建議策略是什麼？分析師對精準發酵的未來有何看法？

目錄

戰略問題

• 為什麼成長如此困難？
• The Strategic Imperative 8（TM）
• 精準發酵產業三大策略挑戰的影響
• 成長機會推動Growth Pipeline Engine（TM）
• 調查方法

成長機會分析

• 傳統發酵的挑戰
• 精密發酵 - 概述
• 精準發酵的分類
• 精準發酵技術類型及比較分析
• 高通量篩選發酵
• 連續發酵
• 連續分批發酵
• pH控制發酵
• 攪拌槽發酵
• 微生物生物反應器發酵
• 主要開發精密發酵技術的公司
• 實現精準發酵的企業
• 精準發酵在終端用途產業的應用－細分
• 生長促進因子
• 成長抑制因素
• 分析範圍

應用分析：化學品和材料

• 化學品和材料的精密發酵 - 概述
• 區域/監管趨勢
• 化學品和材料的發酵—創新生態系統
• 主要使用精密發酵的企業
• 最近的合作夥伴關係和合作，使化學品和材料生產商業化
• 精準發酵對化學品和原料的影響

應用分析：食品和飲料

• 食品和飲料精密發酵 - 概述
• 區域/監管趨勢
• 食品和飲料配料的發酵 - 創新生態系統
• 主要使用精密發酵的企業
• 食品和飲料配料生產商業化的最佳夥伴關係和協作
• 精密發酵對食品和飲料成分的影響

應用分析：製藥

• 醫藥原料精密發酵－概述
• 區域/監管趨勢
• 醫藥原料發酵－創新生態系統
• 發酵藥物成分的臨床前/臨床研究
• 主要使用精密發酵的企業
• 最近在藥物成分生產商業化方面的合作夥伴關係和合作
• 精密發酵對藥物成分的影響

應用分析：個人護理

• 個人護理產品的精密發酵 - 概述
• 區域/監管趨勢
• 個人護理成分發酵 - 創新生態系統
• 發酵個人護理成分的臨床前/臨床研究
• 主要使用精密發酵的企業
• 最近的合作夥伴關係和合作將個人護理成分生產商業化
• 精密發酵對個人護理成分的影響

資金籌措分析

• 精準發酵申請資金籌措（2020-2023）
• 精準發酵資金籌措專案趨勢（2020-2023）
• 精準發酵產業最大受益者（2020-2023）
• 精準發酵產業的重大資金籌措交易

專利分析

• 精準發酵產業智慧財產權活動
• 精密發酵產業知識產權活動（按轄區）
• 精準發酵領域的智慧財產權活動－化學品與材料
• 精密發酵領域的智慧財產權活動 - 化學品和材料（按管轄區）
• 精密發酵領域的智慧財產權活動—食品和飲料
• 精密發酵領域的智慧財產權活動－食品和飲料（依管轄區）
• 精準發酵中的智慧財產權活動-製藥
• 精密發酵領域的智慧財產權活動－製藥（依管轄區）
• 精密發酵中的知識產權活動 - 個人護理
• 精密發酵中的知識產權活動 - 個人護理（按管轄區）

成長機會領域

• 成長機會一：人工智慧與機器人技術在精準發酵領域的融合
• 成長機會2：新的合成生物學技術
• 成長機會3：素食人口的成長

分析師的觀點

• 精密發酵 - 應用影響分析
• 精準發酵的挑戰與克服策略
• 精準發酵的未來

附錄

下一步

Competitive Intensity Enabling Emergence of New High-impact Sustainable Ingredients for Diverse Industries

Conventional fermentation has long been in use, especially for food production. Fermentation applications have expanded to the production of alternate proteins and other ingredients. Traditional fermentation employs microorganisms in their natural state to produce bio-based ingredients for industrial chemicals, biomaterials, pharmaceuticals, food and beverages, and personal care products. Alternatively, biomass fermentation involves culturing protein-dense microorganisms where the rapidly grown microbial biomass becomes the alternative protein ingredient. While conventional fermentation is more sustainable and environmentally friendly than chemical synthesis, the process can only produce a limited diversity of ingredients. Other drawbacks include the large volumes of feedstock needed, low yield and purity, expensive and time-consuming upstream treatments, health risks due to inconsistent quality, and adverse environmental impact from the toxic waste and byproducts.

Precision fermentation, the production of ingredients using optimized or genetically engineered strains in a precisely controlled fermentation process, is the new wave in manufacturing. To meet the growing needs for environmentally friendly chemicals and ingredients, novel ingredients with product-enhancing properties, securing the supply chain, and higher productivity, major players in diverse industries are adopting precision fermentation. The scope of this report only covers precision fermentation technologies in the chemicals and materials, food and beverage, pharmaceutical, and personal care industries, the applications with the greatest impact on precision fermentation.

Collaborations and strategic partnerships are enabling substantial growth in this industry. The United States and Europe are leading precision fermentation innovation and adoption. Major industry players focus on scaling up the production of precision fermentation-derived ingredients and reducing the cost of production. Notably, synthetic biology start-ups are increasingly influencing advances in precision fermentation by enabling the designing of ingredients, making the field a promising growth opportunity for biotechnology companies. Advancements in AI, robotics, and synthetic biology technologies are enabling growth opportunities.

Precision fermentation may not entirely replace conventional ingredients, especially in the food and beverage and personal care industries; however, with increased demand for sustainable ingredients in various industries, it will soon become a mainstream production technology, enabling growth among major players.

Questions This Research Answers:

• What are the industry needs for precision fermentation? What is precision fermentation and its advantages? What are the different types and applications of precision fermentation?

• Who are the major players developing precision fermentation technologies and enabling technologies?

• What are the drivers and restraints for the growth of the precision fermentation industry?

• What are the industry needs and the impact of precision fermentation? What are the regional trends? Who are the participants in the different application segments? What technologies do they employ, and what are the applications of their solutions? Who are the main adopters, and why are they adopting precision fermentation? What are the recent partnership and collaboration activities? What is the impact of precision fermentation on various ingredients in application segments?

• What are the funding and intellectual property (IP) activity trends in the industry?

• What are the growth opportunities for the precision fermentation industry?

• What is the analyst's perspective on the impact of precision fermentation on different applications, recommended strategies to overcome major hurdles in the industry, and the future of precision fermentation?

Table of Contents

Strategic Imperatives

• Why Is It Increasingly Difficult to Grow?The Strategic Imperative 8™: Factors Creating Pressure on Growth
• The Strategic Imperative 8™
• The Impact of the Top 3 Strategic Imperatives on the Precision Fermentation Industry
• Growth Opportunities Fuel the Growth Pipeline Engine™
• Research Methodology

Growth Opportunity Analysis

• Challenges in Conventional Fermentation
• Precision Fermentation-An Overview
• Precision Fermentation Classification
• Types of Precision Fermentation Techniques and Comparative Analysis
• High-throughput Screening Fermentation
• Continuous Fermentation
• Fed-batch Fermentation
• Controlled-pH Fermentation
• Stirred-tank Fermentation
• Microbial Bioreactor Fermentation
• Key Players Developing Precision Fermentation Technologies
• Precision Fermentation Enabling Players
• Applications of Precision Fermentation in End-user Industries-Segmentation
• Growth Drivers
• Growth Restraints
• Scope of Analysis

Application Analysis: Chemicals and Materials

• Precision Fermentation for Chemicals and Materials-Overview
• Regional and Regulatory Trends
• Chemicals and Materials Fermentation-Innovation Ecosystem
• Key Adopters of Precision Fermentation
• Recent Partnerships and Collaborations for Commercializing Chemical and Material Production
• Impact of Precision Fermentation on Chemical and Material Ingredients

Application Analysis: Food and Beverage

• Precision Fermentation for Food and Beverages-Overview
• Regional and Regulatory Trends
• Food and Beverage Ingredient Fermentation-Innovation Ecosystem
• Key Adopters of Precision Fermentation
• Recent Partnerships and Collaborations for Commercializing Food and Beverage Ingredient Production
• Impact of Precision Fermentation on Food and Beverage Ingredients

Application Analysis: Pharmaceuticals

• Precision Fermentation for Pharmaceutical Ingredients-Overview
• Regional and Regulatory Trends
• Pharmaceutical Ingredient Fermentation-Innovation Ecosystem
• Preclinical/Clinical Studies on Fermented Pharmaceutical Ingredients
• Key Adopters of Precision Fermentation
• Recent Partnerships and Collaborations for Commercializing Pharmaceutical Ingredient Production
• Impact of Precision Fermentation on Pharmaceutical Ingredients

Application Analysis: Personal Care

• Precision Fermentation for Personal Care Products-Overview
• Regional and Regulatory Trends
• Personal Care Ingredient Fermentation-Innovation Ecosystem
• Preclinical/Clinical Studies on Fermented Personal Care Ingredients
• Key Adopters of Precision Fermentation
• Recent Partnerships and Collaborations for Commercializing Personal Care Ingredient Production
• Impact of Precision Fermentation on Personal Care Ingredients

Funding Analysis

• Funding across Applications of Precision Fermentation, 2020-2023
• Funding Deal Trends for Precision Fermentation, 2020-2023
• Top Beneficiaries of the Precision Fermentation Industry, 2020-2023
• Notable Funding Deals in the Precision Fermentation Industry

Patent Analysis

• IP Activity in Precision Fermentation Industry
• IP Activity in the Precision Fermentation Industry, by Jurisdiction
• IP Activity in Precision Fermentation-Chemicals and Materials
• IP Activity in Precision Fermentation-Chemicals and Materials, by Jurisdiction
• IP Activity in Precision Fermentation-Food and Beverage
• IP Activity in Precision Fermentation-Food and Beverage, by Jurisdiction
• IP Activity in Precision Fermentation-Pharmaceuticals
• IP Activity in Precision Fermentation-Pharmaceuticals, by Jurisdiction
• IP Activity in Precision Fermentation-Personal Care
• IP Activity in Precision Fermentation-Personal Care Ingredients, by Jurisdiction

Growth Opportunity Universe

• Growth Opportunity 1: Integration of AI and Robotics in Precision Fermentation
• Growth Opportunity 2: Emerging Synthetic Biology Technologies
• Growth Opportunity 3: Growing Vegan Population

Analyst's Perspective

• Precision Fermentation-Application Impact Analysis
• Challenges of Precision Fermentation and Strategies to Overcome
• The Future of Precision Fermentation

Appendix

• Technology Readiness Levels (TRL): Explanation
• Heat Map Analysis Factors-Definitions

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