Cryo-Electron Microscopy - Global Market Outlook (2021 - 2028)
According to Stratistics MRC, the Global Cryo-Electron Microscopy Market is accounted for $725.43 million in 2021 and is expected to reach $1,525.20 million by 2028 growing at a CAGR of 11.2% during the forecast period. Cryo-electron microscopy is a procedure for imaging frozen-hydrated samples at cryogenic temperatures through electron microscopy. Specimens persevere in their natural state without the need for colors or fixatives, letting the study of adequate viruses, cellular structures and protein multifarious at molecular resolution. Cryo electron microscope is different from using normal microscope. It involves freezing the biological sample in order to view the sample with the least possible distortion and the fewest possible artefacts. Biologists use cryo-electron microscopy to capture pictures of biological samples that have been frozen in their natural states. Cryo electron microscope is faster and effective as compared to other structural biology tools.
Rapid technological advancements
New technological advancements is one of the trend in global cryo electron microscope market. The rapid technological advancements and improvement of capabilities such as faster processing and efficient sample preparation techniques is amongst the important factors intensifying the growth and demand of cryo-electron microscopy market. In addition, the increasing focus on nanotechnology and regenerative medicine is also contributing to the growth in the global market over the forecast period. Additionally, the integration of display modalities with these advancements to enhance 3-D images and high definition will fuel the demand of cryo-electron microscopy in various applications, which is likely to drive the cryo-electron microscopy market globally.
High cost of cryo electron microscope
Cryo-EM microscopes are very expensive instruments. The cryo electron microscopy technique is costly, and it takes time to generate the sample also fully hydrated specimen is electron-beam sensitive, which can hamper the growth of Cryo-electron microscopy in coming years. Configurations, customizations, sample accommodation, components, and achieved resolution are the ultimate drivers in the cost of the cryo-electron microscope. However, there are other notable costs that are often overlooked during the buying process. Training, setup and deployment, as well as logistical costs can all contribute to the total cost of ownership of a cryo-electron microscope.
Favourable funding scenario for R&D
The favourable funding scenario for R&D in microscopy as well as increase in healthcare expenditure and rise in venture capital investments are also enhancing the growth of the market. The rapid increase in viruses and chronic diseases has led to high investment in R&D also the manufacturers are investing heavily to expand and introduce technological advance cryo electron microscope which will further accelerate the expansion of the cryo-electron microscopy market and are also are offering significant growth opportunities for the market in the forecast period. Key players are highly present in North America and Europe owing to the availability of adequate R&D facility.
Dearth of skilled professionals
Although Cryo-EM offers high overall magnification, one of the major disdvantage of Cryo-Electron microscope is it provides a very low signal to noise ratio. For biological macromolecules, the critical building blocks include carbon, hydrogem oxygen, and nitrogen. Given that electron absorption of these molecules is very low, then there is little contrast of the resulting images that make it challenging to detect features of a given sample when viewing a few samples.
The nanotechnology segment is expected to be the largest during the forecast period
The nanotechnology segment is estimated to have a lucrative growth. The nanotechnology segment is expected to expand in the forecast period as compared to the other segments. Nanotechnology is attributed to multiple applications in various fields such as medicine, space program, fabric development, food, fuel cell, solar cell and water purification. There are various development activities and research on nanotechnology and this is considered as one of the driving factors for the growth of this segment.
The cryo-electron tomography segment is expected to have the highest CAGR during the forecast period
The cryo-electron tomography segment is anticipated to witness the fastest CAGR growth during the forecast period. The cryo-electron tomography segment is likely to register the highest CAGR in the future, owing to its high-quality resolution, which has resulted in easy identification of specimens on deeper levels. Additionally, cryo-electron tomography increases cryo-electron microscopy's applicability in chemistry to study the structures of compounds, as it allows imaging at a molecular level, and in biology, as these are used to understand viruses and bacteria.
Region with highest share:
North America is projected to hold the largest market share during the forecast period owing to rapidly increasing adoption of advanced technology and higher health coverage within the region. Cryo electron microscope market has various applications in fields such as medicine, space program, fabric development, food, fuel cell, solar cell and water purification which will boost the North American cryo electron microscope market. Government and multiple technology firms are focusing on developing nanotechnology due to its rise in multiple applications and are investing in cryo electron microscope technology. Cryo electron microscope market in the region is expanding due to increase in number of well-equipped diagnostic centers and ongoing clinical trials.
Region with highest CAGR:
Asia Pacific is projected to have the highest CAGR over the forecast period owing to the rapid technological advancements, increase in healthcare expenditure and rise in venture capital investments within this particular region. Global companies are interested to meet the health requirements in countries such as India, China and Japan. There has been exponential rise in investments in multiple industries such as pharmaceuticals and consumer electronics and this will contribute to the cryo electron microscope market in this region and flourishing medical tourism and development in the health care infrastructure will support the market in future and is expected to expand in the forecast period.
Key players in the market
Some of the key players profiled in the Cryo-Electron Microscopy Market include Amgen, Cray Inc, Creative Bio Structure, Delong, Frealign, Hitachi, JEOL, Nvidia Corporation, Relion, Sapphire, Sparx, Structura Biotechnology Inc, Thermo Fisher Scientific, Xmipp, and Zeiss.
In October 2021, Amgen and USC are teaming up to provide researchers with access to two leading-edge Thermo Scientific cryo-transmission electron microscopes (cryo-TEMs): the Thermo Scientific Krios and Glacios Cryo-TEMs.
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Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.