市場調查報告書

人體肝臟模式的全球市場 - 調查及預測

Global Human Liver Model Market Research and Forecast, 2019-2025

出版商 Orion Market Research Pvt Ltd 商品編碼 825143
出版日期 內容資訊 英文
商品交期: 2-3個工作天內
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人體肝臟模式的全球市場 - 調查及預測 Global Human Liver Model Market Research and Forecast, 2019-2025
出版日期: 2019年04月06日內容資訊: 英文
簡介

本報告以人體肝臟模式的全球市場為焦點,探討其整體情況與發展性,在法規環境和競爭環境,經濟、產業趨勢背景下的發展推動、阻礙因素、機會等,及各市場產品領域及地區之直接取材及二次資訊調查、分析所得之資料及數據,並提供參與企業的事業發展相關最新的調查資訊。

第1章 報告摘要

  • 調查的方法與工具
  • 市場區隔
    • 各領域
    • 各地區
    • 各相關利益者

第2章 市場概要與考察

  • 報告目標範圍
  • 分析師的考察和目前市場趨勢
    • 重要發現
    • 建議
    • 結論
  • 相關法與法規

第3章 競爭環境

  • 競爭儀表板
  • 主要對策分析
  • 主要企業分析
    • 企業概要
    • 財務分析
    • SWOT分析
    • 最新展開

第4章 市場決策要素

  • 推動要素
  • 阻礙因素
  • 發展機會

第5章 市場區隔

  • 人體肝臟模式的全球市場 - 各技術
    • 肝臟器官(培養肝臟)
    • 3D生物印刷
    • 2D模式
    • 肝臟晶片(Liver-On-A-Chip)
    • 其他

第6章 各地區分析

  • 北美
    • 美國
    • 加拿大
  • 歐洲
    • 英國
    • 德國
    • 義大利
    • 西班牙
    • 法國
    • 其他歐洲
  • 亞太地區
    • 中國
    • 印度
    • 日本
    • 其他亞太地區
  • 其他地區

第7章 企業簡介

  • BioIVT, LLC
  • CN Bio Innovations Ltd.
  • Cyfuse Biomedical K.K.
  • Cyprotex PLC
  • EISCO Scientific LLC
  • Emulate, Inc.
  • InSphero AG
  • MIMETAS B.V.
  • Organovo Holdings, Inc.
  • Poietis SAS
  • Strand Life Sciences Pvt. Ltd.
目錄
Product Code: OMR2019618

Human Liver Model Market Size, Share & Trends Analysis Report, By Technology (Liver Organoids, 3D Bioprinting, 2D Models, Liver-On-A-Chip and Other), and Forecast, 2019-2025.

Human liver model is a structure that is intended for studying the toxicity associated with the drug which may result in liver failure and other liver diseases. This enables to develop a better understanding of liver disease and complex spatial relationships of the internal anatomy of the liver. Furthermore, various researches have reported for the development of human liver models to determine the sensitivity of drugs across a large amount of population. For instance, in February 2018, the Wake Forest Institute for Regenerative Medicine (WFIRM) created highly sophisticated mini-livers up to the current period. Such organoids can effectively support scientists to develop a better understanding of congenital liver disease. The model better mimics human liver functioning and fetal development. According to the center, these organoids are expected to advance their understanding of liver diseases, primarily congenital diseases that would enable for the development of improved treatments. This may support towards improving bioengineering of functional liver and bile ducts. The funding for the research was led by the state of North Carolina and the National Institutes of Health (NIH).

The research is remarkable in the area of liver transplantation and the study of biliary atresia which occurs in infants. Firstly, the scientists represented that such organoids generated hepatocytes which is capable to perform a large number of liver functions. The success for development of this model shows a major step towards the development of truly bioengineered liver tissue which is intended to transplantation into patients. This is exploring the significant opportunity for patients that require liver transplants. According to the American Liver Foundation, in 2016, in the US, the number of liver transplants performed were 7,841. Among these, 7,496 liver transplants were reported from deceased donors and 345 were from living donors. Additionally, as of February 2016, in the US, the reported number of patients waiting for liver transplants were 14,380. The development of such kind of human liver model is estimated to create new hope for patients that are waiting for liver transplant. It can overcome the problem associated with organ shortage. Other crucial factors that are contributing to the growth of the market include increasing prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD) and rising focus of clinicians, pharmaceutical companies and academics towards drug-induced liver injury.

The global human liver model market is segmented on the basis of technology. Based on technology, the market is further classified into liver organoids, 3D bioprinting, 2D models, and liver-on-a-chip. These technologies utilize various cell source include primary hepatocytes, iPSC-derived, HepaRG, HepG2, and UpCyte. Primary hepatocytes represent approximately 60% of the total number of cells in the liver. Hence, it can perform a large number of liver functions and are usually accepted as the gold standard for building human liver models for drug testing and toxicity applications.

Geographically, the global human liver model market is segmented into four major regions, such as North America, Europe, Asia-Pacific, and RoW. North America was estimated to hold the largest share in 2017. This is resulting due to funding for the development of human liver models and significant healthcare spending in the region. However, Asia-Pacific is estimated to witness optimistic growth during the forecast period due to the increasing prevalence of NAFLD and improving healthcare infrastructure.

The major companies working in the market comprise InSphero AG, BioIVT, LLC, and Organovo Holdings, Inc. These companies are adopting several strategies, such as merger and acquisitions, product launches and collaboration and partnership to expand market share. For instance, in March 2018, BioIVT, LLC acquired Ascendance Biotechnology, which was established in 2015 from the merger of BioTime Inc.'s ESI BIO products division and Hepregen Corp. to develop a multinational cell-based assay firm. With this acquisition, BioIVT is including Hepregen's HepatoMune, HepatoStem, and HepatoPac stem cell and liver cell product lines to its drug toxicology and drug safety testing portfolios. BioIVT has anticipated that widened use of highly functional Hepregen's, in-vitro liver models would develop a significant understanding of the toxicity that results from long-term exposure to chemical compounds. This, in, turn, would support drug pre-clinical testing and other screening processes.

Research Methodology

The market study of the global human liver model market is incorporated by extensive primary and secondary research conducted by the research team at OMR. Secondary research has been conducted to refine the available data to breakdown the market in various segments, derive total market size, market forecast, and growth rate. Different approaches have been worked on to derive the market value and market growth rate. Our team collects facts and data related to the market from different geography to provide a better regional outlook. In the report, the country-level analysis is provided by analyzing various regional players, regional tax laws and policies, consumer behavior and macro-economic factors. Numbers extracted from Secondary research have been authenticated by conducting proper primary research. It includes tracking down key people from the industry and interviewing them to validate the data. This enables our analyst to derive the closest possible figures without any major deviations in the actual number. Our analysts try to contact as many executives, managers, key opinion leaders, and industry experts. Primary research brings authenticity in our reports.

Secondary Sources Include:

  • Financial reports of companies involved in the market.
  • Authentic public databases
  • Whitepapers, research-papers, and news blogs.
  • Company websites and their product catalog.

The report is intended for research institutes, government and private companies for overall market analysis and competitive analysis. The report provides in-depth analysis on market size, intended quality of the service preferred by consumers. The report will serve as a source for 360-degree analysis of the market thoroughly integrating different models.

The Report Covers:

  • Comprehensive research methodology of the global human liver model market.
  • This report also includes a detailed and extensive market overview with key analyst insights.
  • An exhaustive analysis of macro and micro factors influencing the market guided by key recommendations.
  • Analysis of regional regulations and other government policies impacting the global human liver model market.
  • Insights about market determinants which are stimulating the global human liver model market.
  • Detailed and extensive market segments with regional distribution of forecasted revenues.
  • Extensive profiles and recent developments of market players.

Table of Contents

1. Report Summary

  • 1.1. Research Methods and Tools
  • 1.2. Market Breakdown
    • 1.2.1. By Segments
    • 1.2.2. By Geography
    • 1.2.3. By Stakeholders

2. Market Overview and Insights

  • 2.1. Scope of the Report
  • 2.2. Analyst Insight & Current Market Trends
    • 2.2.1. Key Findings
    • 2.2.2. Recommendations
    • 2.2.3. Conclusion

3. Competitive Landscape

  • 3.1. Competitive Dashboard
  • 3.2. Key Strategy Analysis
  • 3.3. Key Company Analysis
    • 3.3.1. Overview
    • 3.3.2. Financial Analysis
    • 3.3.3. SWOT Analysis
    • 3.3.4. Recent Developments

4. Market Determinants

  • 4.1. Motivators
  • 4.2. Restraints
  • 4.3. Opportunities

5. Market Segmentation

  • 5.1. Global Human Liver Model Market by Technology
    • 5.1.1. Liver Organoids
    • 5.1.2. 3D Bioprinting
    • 5.1.3. 2D Models
    • 5.1.4. Liver-On-A-Chip
    • 5.1.5. Other

6. Regional Analysis

  • 6.1. North America
    • 6.1.1. United States
    • 6.1.2. Canada
  • 6.2. Europe
    • 6.2.1. UK
    • 6.2.2. Germany
    • 6.2.3. Italy
    • 6.2.4. Spain
    • 6.2.5. France
    • 6.2.6. Rest of Europe
  • 6.3. Asia-Pacific
    • 6.3.1. China
    • 6.3.2. Japan
    • 6.3.3. India
    • 6.3.4. Rest of Asia-Pacific
  • 6.4. Rest of the World

7. Company Profiles

  • 7.1. BioIVT, LLC
  • 7.2. CN Bio Innovations Ltd.
  • 7.3. Cyfuse Biomedical K.K.
  • 7.4. Cyprotex PLC
  • 7.5. EISCO Scientific LLC
  • 7.6. Emulate, Inc.
  • 7.7. InSphero AG
  • 7.8. MIMETAS B.V.
  • 7.9. Organovo Holdings, Inc.
  • 7.10. Poietis SAS
  • 7.11. Strand Life Sciences Pvt. Ltd.

List of Tables

    1.GLOBAL HUMAN LIVER MODEL MARKET RESEARCH AND ANALYSIS BY TECHNOLOGY, 2018-2025 ($ MILLION)

  • 2. GLOBAL LIVER ORGANOIDS MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)
  • 3. GLOBAL 3D BIOPRINTING MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)
  • 4. GLOBAL 2D MODELS MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)
  • 5. GLOBAL LIVER-ON-A-CHIP MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)
  • 6. GLOBAL OTHER MARKET RESEARCH AND ANALYSIS BY REGION, 2018-2025 ($ MILLION)
  • 7. GLOBAL HUMAN LIVER MODEL MARKET RESEARCH AND ANALYSIS BY GEOGRAPHY, 2018-2025 ($ MILLION)
  • 8. NORTH AMERICAN HUMAN LIVER MODEL MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2018-2025 ($ MILLION)
  • 9. NORTH AMERICAN HUMAN LIVER MODEL MARKET RESEARCH AND ANALYSIS BY TECHNOLOGY, 2018-2025 ($ MILLION)
  • 10. EUROPEAN HUMAN LIVER MODEL MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2018-2025 ($ MILLION)
  • 11. EUROPEAN HUMAN LIVER MODEL MARKET RESEARCH AND ANALYSIS BY TECHNOLOGY, 2018-2025 ($ MILLION)
  • 12. ASIA-PACIFIC HUMAN LIVER MODEL MARKET RESEARCH AND ANALYSIS BY COUNTRY, 2018-2025 ($ MILLION)
  • 13. ASIA-PACIFIC HUMAN LIVER MODEL MARKET RESEARCH AND ANALYSIS BY TECHNOLOGY, 2018-2025 ($ MILLION)
  • 14. REST OF THE WORLD HUMAN LIVER MODEL MARKET RESEARCH AND ANALYSIS BY TECHNOLOGY, 2018-2025 ($ MILLION)

List of Figures

  • 1. GLOBAL HUMAN LIVER MODEL MARKET SHARE BY TECHNOLOGY, 2018 VS 2025 (%)
  • 2. GLOBAL HUMAN LIVER MODEL MARKET SHARE BY GEOGRAPHY, 2018 VS 2025 (%)
  • 3. US HUMAN LIVER MODEL MARKET SIZE, 2018-2025 ($ MILLION)
  • 4. CANADA HUMAN LIVER MODEL MARKET SIZE, 2018-2025 ($ MILLION)
  • 5. UK HUMAN LIVER MODEL MARKET SIZE, 2018-2025 ($ MILLION)
  • 6. FRANCE HUMAN LIVER MODEL MARKET SIZE, 2018-2025 ($ MILLION)
  • 7. GERMANY HUMAN LIVER MODEL MARKET SIZE, 2018-2025 ($ MILLION)
  • 8. ITALY HUMAN LIVER MODEL MARKET SIZE, 2018-2025 ($ MILLION)
  • 9. SPAIN HUMAN LIVER MODEL MARKET SIZE, 2018-2025 ($ MILLION)
  • 10. ROE HUMAN LIVER MODEL MARKET SIZE, 2018-2025 ($ MILLION)
  • 11. INDIA HUMAN LIVER MODEL MARKET SIZE, 2018-2025 ($ MILLION)
  • 12. CHINA HUMAN LIVER MODEL MARKET SIZE, 2018-2025 ($ MILLION)
  • 13. JAPAN HUMAN LIVER MODEL MARKET SIZE, 2018-2025 ($ MILLION)
  • 14. REST OF ASIA-PACIFIC HUMAN LIVER MODEL MARKET SIZE, 2018-2025 ($ MILLION)
  • 15. REST OF THE WORLD HUMAN LIVER MODEL MARKET SIZE, 2018-2025 ($ MILLION)
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