Molecular Weight Marker Market - Growth, Trends, COVID-19 Impact, and Forecasts (2022 - 2027)
The global molecular weight marker market is expected to witness a CAGR of 11.7% during the forecast period. Certain factors that are driving the market growth include increasing investment in R&D and growing focus on proteomics and genomics technologies research.
One of the major factors responsible for driving the growth of the global molecular market is the investments being made in the R&D of molecular biology, which involves the use of molecular markers. In 2017, an investment of USD 1.4 million by the Magnotta Foundation to fund Lyme disease research, which requires specific study of these disease characteristics through the use of molecular markers, increased the focus on the use of molecular markers in molecular biology.
The University of Leeds has also invested GBP 17 million in structural biology research, which would further involve the use of molecular markers in more than 50% of their research activities. These huge investments in research in specific areas that involve molecular markers, along with the increasing focus on molecular research biology, are expected to drive the growth of the molecular marker market over the forecast period.
However, the lack of skilled professionals in the field of molecular weight markers to conduct the research process and use these markers efficiently is restricting the use of molecular weight markers in the market.
RNA molecular weight markers consist of a mixture of in vitro synthesized chains of defined lengths, for the molecular-weight determination of RNA species. Markers are dissolved in a storage buffer, such as EDTA, and have a shelf life of up to 2 years when stored at -80 °C. The markers are usually stained, to be detectable on gel electrophoresis. The most commonly used dye for markers is ethidium bromide. They are usually used as size standards in northern blotting and RNA gel electrophoresis. The fragments are prepared by in vitro transcription of linearized plasmids, with RNA polymerases in separate reactions.
Digoxigenin (DIG)-labeled RNA markers are widely used, as they are more stable and can be used multiple times without losing activity. Roche is the key player in the RNA molecular weight marker segment. Moreover, these markers are essential in research and development of new therapies and drugs, which has increased over the years. As a result, the demand for RNA markers is also expected to increase, which will help the market growth.
The North American market is highly driven by the presence of many large research laboratories and biotechnology in the United States. Applications of molecular weight markers, such as gel electrophoresis, PCR, molecular cloning, and sequencing, are very commonly used for the research in biotech companies.
The increasing number of biotech companies in the United States is expected to drive the molecular weight markers market. Roche has invested in Stratos Genomics, a US-based biotech company, and has entered into a research collaboration to support further development of its unique application of single molecule sequencing of DNA fragments, using protein nanopores. Roche is working with Stratos scientists to support the development of efficient, low-cost sample preparation methods for DNA Xpandomers and improve sequencing performance. Collaborations between biotech companies and academia are increasing in the United States. These factors are driving the molecular weight markers market in the country.
The molecular weight marker market is highly competitive and consists of a number of major players. Companies, like Agilent Technologies, Bio-Rad Laboratories, F Hoffmann-La Roche, Merck KGaA, New England Biolabs, Promega Corporation, Qiagen, Thermo Fisher Scientific, and VWR International, among others, hold the substantial market share in the market studied.