表紙
市場調查報告書

血液凝固凝血因子XI (血漿凝血酵素原前驅物質) :開發中產品分析

Coagulation Factor XI - Pipeline Review, H2 2019

出版商 Global Markets Direct 商品編碼 363581
出版日期 內容資訊 英文 70 Pages
訂單完成後即時交付
價格
Back to Top
血液凝固凝血因子XI (血漿凝血酵素原前驅物質) :開發中產品分析 Coagulation Factor XI - Pipeline Review, H2 2019
出版日期: 2019年12月27日內容資訊: 英文 70 Pages
簡介

本報告提供血液凝固凝血因子XI (血漿凝血酵素原前驅物質)的開發情形相關的資訊,各開發階段、藥物標的、作用機制、給藥途徑及各分子類型的分析,開發治療藥的企業概要,最新消息和新聞稿等資訊,為您概述為以下內容。

簡介

  • 調查範圍

血液凝固凝血因子XI (血漿凝血酵素原前驅物質)的概要

治療藥的開發

血液凝固凝血因子XI (血漿凝血酵素原前驅物質):開發中的產品 - 各開發階段

血液凝固凝血因子XI (血漿凝血酵素原前驅物質):開發中的產品 - 各治療範圍

血液凝固凝血因子XI (血漿凝血酵素原前驅物質):開發中的產品 - 各適應症

血液凝固凝血因子XI (血漿凝血酵素原前驅物質):開發中產品概況

  • 後期階段的產品
  • 初期階段的產品

血液凝固凝血因子XI (血漿凝血酵素原前驅物質):企業開發中的產品

血液凝固凝血因子XI (血漿凝血酵素原前驅物質):大學/機關開發中的產品

血液凝固凝血因子XI (血漿凝血酵素原前驅物質):治療藥的評估

  • 各單劑療法/聯合治療產品
  • 各作用機制
  • 各給藥途徑
  • 各分子類型

血液凝固凝血因子XI (血漿凝血酵素原前驅物質)的治療藥的開發企業

  • Bayer AG
  • Bristol-Myers Squibb Company
  • Cambryn Biologics LLC
  • eXithera Pharmaceuticals, Inc
  • Ionis Pharmaceuticals, Inc.
  • LegoChem Biosciences, Inc

藥物簡介

血液凝固凝血因子XI (血漿凝血酵素原前驅物質):暫停中的計劃

血液凝固凝血因子XI (血漿凝血酵素原前驅物質):主要消息和新聞稿

附錄

本網頁內容可能與最新版本有所差異。詳細情況請與我們聯繫。

目錄
Product Code: GMDHC2057TDB

Summary

Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) - Factor XI or plasma thromboplastin antecedent is the zymogen form of factor Xia. Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. Inhibitors of factor XIa include protein Z-dependent protease inhibitor.

Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) pipeline Target constitutes close to 22 molecules. Out of which approximately 21 molecules are developed by companies and remaining by the universities/institutes. The molecules developed by companies in Phase II, Phase I and Preclinical stages are 4, 11 and 6 respectively. Similarly, the universities portfolio in Preclinical stages comprises 1 molecules, respectively. Report covers products from therapy areas Cardiovascular, Hematological Disorders and Infectious Disease which include indications Thrombosis, Arterial Thrombosis, Bleeding And Clotting Disorders, Venous Thromboembolism, Venous (Vein) Thrombosis, Acute Ischemic Stroke, Hemophilia C (Factor XI Deficiency), Sepsis, Cerebral Infarction (Brain Infarction), Hemorrhagic Fever and Stroke.

The latest report Coagulation Factor XI - Pipeline Review, H2 2019, outlays comprehensive information on the Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviews key players involved in Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) targeted therapeutics development with respective active and dormant or discontinued projects.

The report is built using data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.

Scope

  • The report provides a snapshot of the global therapeutic landscape for Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27)
  • The report reviews Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
  • The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
  • The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
  • The report reviews key players involved in Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) targeted therapeutics and enlists all their major and minor projects
  • The report assesses Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
  • The report summarizes all the dormant and discontinued pipeline projects
  • The report reviews latest news and deals related to Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) targeted therapeutics

Reasons to buy

  • Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
  • Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
  • Identify and understand the targeted therapy areas and indications for Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27)
  • Identify the use of drugs for target identification and drug repurposing
  • Identify potential new clients or partners in the target demographic
  • Develop strategic initiatives by understanding the focus areas of leading companies
  • Plan mergers and acquisitions effectively by identifying key players and it's most promising pipeline therapeutics
  • Devise corrective measures for pipeline projects by understanding Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) development landscape
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Table of Contents

List of Tables

List of Figures

  • Introduction
  • Global Markets Direct Report Coverage
  • Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) - Overview
  • Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) - Therapeutics Development
  • Products under Development by Stage of Development
  • Products under Development by Therapy Area
  • Products under Development by Indication
  • Products under Development by Companies
  • Products under Development by Universities/Institutes
  • Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) - Therapeutics Assessment
  • Assessment by Mechanism of Action
  • Assessment by Route of Administration
  • Assessment by Molecule Type
  • Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) - Companies Involved in Therapeutics Development
  • Anthos Therapeutics Inc
  • Aronora Inc
  • Bayer AG
  • Bio Products Laboratory Ltd
  • Bristol-Myers Squibb Co
  • Cambryn Biologics LLC
  • eXithera Pharmaceuticals Inc
  • Ionis Pharmaceuticals Inc
  • Jiangsu Hengrui Medicine Co Ltd
  • Mochida Pharmaceutical Co Ltd
  • Ono Pharmaceutical Co Ltd
  • Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) - Drug Profiles
  • 7300 Series - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • AB-012 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • AB-022 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • BAY-1831865 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • BMS-262084 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • BMS-654457 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • BMS-962212 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • BMS-986177 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • coagulation factor XI (human) - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • coagulation factor XI (human) - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • coagulation factor XI (human) - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • EP-7041 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • IONIS-FXILRx - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • IONIS-FXIRx - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • MAA-868 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • MR-1007 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • ONO-7269 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • ONO-7684 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • osocimab - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • SHR-2285 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • Small Molecule to Inhibit Activated Factor XI for Bleeding Disorders - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • Small Molecules to Inhibit Factor XI for Bleeding And Clotting Disorders - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • Small Molecules to Inhibit Factor XIa for Arterial Thrombosis - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress
  • Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) - Dormant Products
  • Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) - Discontinued Products
  • Coagulation Factor XI (Plasma Thromboplastin Antecedent or F11 or EC 3.4.21.27) - Product Development Milestones
  • Featured News & Press Releases
  • Oct 28, 2019: Ionis Pharmaceuticals presents on its drug candidate IONIS-FXI-LRx at DIA/FDA Oligonucleotide Conference
  • Oct 09, 2019: Ionis' Factor XI anti-thrombotic medicine advances with Bayer following positive clinical results
  • Nov 13, 2017: eXIthera Presents Clinical Data on Novel Small Molecule FXIa Inhibitor EP-7041 at American Heart Association
  • Jul 03, 2017: Bayer To Present Data on BAY 1213790 at ISTH 2017
  • Nov 01, 2016: Ionis Pharmaceuticals Reports Positive Phase 2 Data for IONIS-FXI Rx in Patients with End-Stage Renal Disease on Hemodialysis
  • Jul 04, 2016: MorphoSys Receives Clinical Milestone for Start of Phase 1 Trial in Prevention of Thrombosis with Novel Antibody
  • Oct 30, 2015: Isis Pharmaceuticals Initiates Phase 2 Study of ISIS-FXI Rx in Patients with End-Stage Renal Disease on Hemodialysis
  • Feb 24, 2015: Bayer HealthCare and Aronora Establish Partnership for the Pre-Clinical Manufacturing of AB-022
  • Dec 07, 2014: Isis Pharmaceuticals Reports Positive Phase 2 Data for ISIS-FXI Rx for the Prevention of Venous Thrombosis in Patients Undergoing Total Knee Replacement Surgery
  • Nov 18, 2014: Isis Pharmaceuticals To Host Webcast To Discuss ISIS-FXI Rx Data Presented At The ASH Annual Meeting
  • May 22, 2014: Isis Pharmaceuticals Reports Positive Phase 2 Data for ISIS-FXI Rx in the Prevention of Venous Thrombosis in Patients Undergoing Total Knee Replacement Surgery
  • May 22, 2014: Cambryn Biologics Receives From FDA Orphan Drug Designation For Human Factor XI
  • Apr 19, 2013: CML HealthCare's Subsidiary Hemostasis Reference Labs Receives Contract Extension From Isis Pharma
  • Oct 29, 2012: Isis Pharma Initiates Phase II Study Of ISIS-FXIRX In Patients Undergoing Knee Replacement Surgery
  • Dec 12, 2011: Isis Reports Positive Phase I Data Demonstrating ISIS-FXIRx Reduces Factor XI Activity Without Bleeding
  • Appendix
  • Methodology
  • Coverage
  • Secondary Research
  • Primary Research
  • Expert Panel Validation
  • Contact Us
  • Disclaimer

List of Tables

  • Number of Products under Development by Stage of Development, H2 2019
  • Number of Products under Development by Therapy Areas, H2 2019
  • Number of Products under Development by Indication, H2 2019
  • Number of Products under Development by Companies, H2 2019
  • Products under Development by Companies, H2 2019
  • Products under Development by Companies, H2 2019 (Contd..1), H2 2019
  • Number of Products under Investigation by Universities/Institutes, H2 2019
  • Products under Investigation by Universities/Institutes, H2 2019
  • Number of Products by Stage and Mechanism of Actions, H2 2019
  • Number of Products by Stage and Route of Administration, H2 2019
  • Number of Products by Stage and Molecule Type, H2 2019
  • Pipeline by Anthos Therapeutics Inc, H2 2019
  • Pipeline by Aronora Inc, H2 2019
  • Pipeline by Bayer AG, H2 2019
  • Pipeline by Bio Products Laboratory Ltd, H2 2019
  • Pipeline by Bristol-Myers Squibb Co, H2 2019
  • Pipeline by Cambryn Biologics LLC, H2 2019
  • Pipeline by eXithera Pharmaceuticals Inc, H2 2019
  • Pipeline by Ionis Pharmaceuticals Inc, H2 2019
  • Pipeline by Jiangsu Hengrui Medicine Co Ltd, H2 2019
  • Pipeline by Mochida Pharmaceutical Co Ltd, H2 2019
  • Pipeline by Ono Pharmaceutical Co Ltd, H2 2019
  • Dormant Projects, H2 2019
  • Discontinued Products, H2 2019

List of Figures

  • Number of Products under Development by Stage of Development, H2 2019
  • Number of Products under Development by Therapy Areas, H2 2019
  • Number of Products under Development by Top 10 Indications, H2 2019
  • Number of Products by Mechanism of Actions, H2 2019
  • Number of Products by Stage and Mechanism of Actions, H2 2019
  • Number of Products by Routes of Administration, H2 2019
  • Number of Products by Stage and Routes of Administration, H2 2019
  • Number of Products by Molecule Types, H2 2019
  • Number of Products by Stage and Molecule Types, H2 2019
Back to Top