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免疫神經藥的開發動

Neuroimmunology Drug Development

出版商 GlobalData 商品編碼 772768
出版日期 內容資訊 英文 76 Pages
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免疫神經藥的開發動 Neuroimmunology Drug Development
出版日期: 2018年12月17日內容資訊: 英文 76 Pages
簡介

本報告提供全球免疫神經藥市場上新產品臨床實驗、開發趨勢相關分析,免疫神經產品的定義及分類方法和共通標的,目前臨床實驗的進展(各疾病、各階段、各地區等)、10家最大企業的概要和主要產品,今後的技術、市場趨勢的專家的見解等資訊彙整,為您概述為以下內容。

第1章 簡介

第2章 摘要整理

第3章 神經免疫產品的定義與分類

第4章 神經免疫學的通用目標:概要

  • 細胞激素
  • 淋巴球/分子,和活性化、融合作用的關聯性
  • 其他共通標的:神經免疫產品的情況

第5章 已上市神經免疫產品的評估

  • 症狀、分子的種類
  • 標的的種類

第6章 開發平台上的神經免疫產品的評估

  • 產品一覽:各臨床實驗階段 (開發階段)
  • 產品一覽:各分子類型
  • 產品一覽:各標的

第7章 特定症狀分析:多發性硬化症 (MS)

  • 疾病的概要與流行病學
  • 產品開發活動
  • 臨床實驗的最後階段的產品的簡介

第8章 特定症狀分析:阿茲海默症 (AD)

  • 疾病的概要與流行病學
  • 產品開發活動
  • 臨床實驗的最後階段的產品的簡介

第9章 免疫神經藥臨床實驗趨勢

  • 現在進行中的臨床實驗:各活動據點的趨勢
  • 現在進行中的臨床實驗:各相位、各後援企業的趨勢
  • 現在進行中的臨床實驗:分析對象的各症狀的趨勢
  • 聯合治療的趨勢
  • 神經免疫市場內部的未滿足需求

第10章 附錄

目錄
Product Code: GDHCHT019

Among the different molecule types in neuroimmunology, mAbs and small molecules are the most common. This is primarily due to the specificity of the former and the ability of the latter to penetrate the BBB. However, the cost factor associated with mAbs-based therapy is seen as a hurdle for wider market acceptances.

Neuroimmunology is expected to be an area that will witness strong growth in the future due to a number of factors such as deeper understanding of the underlying disease pathology, advancements in neurogenetics, and potential of these drugs that can contribute to targeted therapy. Pipeline drugs targeting a number of neurology indications are being developed; however, the most common ones are Alzheimer's disease (AD) and Multiple Sclerosis (MS).

The most common targets adopted by pipeline drugs for MS include cytokines or cytokine receptors, as well as lymphocytes or molecule s associated with their activation or migration. The majority of pipeline drugs for AD are aimed at targeting the AB protein, the historical results of which have not been strong enough to be assigned as a breakthrough therapy.

The KOLs interviewed have highlighted the high cost of therapy associated with a mAb based therapy which is perceived as a hurdle for such drugs to be widely accepted in the market; this factor is expected to lead companies to develop more cost-efficient therapies based on alternate molecule types. They've also expressed the need for long-term safety and clinical data, as well as data to help them with decisions on sequential or combination therapies in neuroimmunology. These challenges are compounded when rare diseases are considered, primarily those related to patient recruitment.

The "Neuroimmunology Drug Development", report combines primary research from a cross-specialty panel of neurology experts with in-house analyst expertise to provide an assessment of the development landscape. This report provides an overview of current clinical and product development trends for neuroimmunology within the 8MM (France, Germany, Italy, Spain, UK, US, Japan, China), including analysis of the most common targets and molecule types that are being evaluated among the current pipeline drugs, focus on product development in indications such as AD and MS, and unmet needs within neuroimmunology.

Scope:

This report combines primary research from a cross-specialty panel of neurology experts with in-house analyst expertise to provide an assessment of the development landscape. Components of the slide deck include primary and secondary research -

  • Quotes from 10 key opinion leaders (3 US, 5 EU, 1 Japan, 1 China)
  • Summary of neuroimmunology product definitions and classifications
  • Overview of common targets and molecule types among current pipeline drugs, with focus on product development in AD and MS
  • Trends in ongoing clinical trials in neuroimmunology based on sponsor type, and phase of development
  • Call-outs of key information and details
  • Insight from GlobalData's specialist neurology analysts.

Reasons to buy:

  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the neuroimmunology market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the neuroimmunology market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analysing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.

Table of Contents

1. Introduction

  • 1.1. Related Reports
  • 1.2. Upcoming Related Reports

2. Executive Summary

  • 2.1. Key Findings
  • 2.2. KOL Insights on Neuroimmunology Competitive Landscape

3. Neuroimmunology Product Definition and Classification

  • 3.1. GlobalData's Definition of Neuroimmunology Products

4. Overview of Common Targets in Neuroimmunology

  • 4.1. Cytokines
  • 4.2. Lymphocytes or Molecules Associated with their Activation or Migration
  • 4.3. Other Common Targets in Neuroimmunology

5. Assessment of Marketed Neuroimmunology Products

  • 5.1. Indications and Molecule Types
  • 5.2. Target Types

6. Assessment of Pipeline Neuroimmunology Products

  • 6.1. Products in Different Phases of Development
  • 6.2. Products by Different Molecule Types
  • 6.3. Products by Different Targets

7. Indication Specific Overview: Multiple Sclerosis

  • 7.1. Disease Overview and Epidemiology
  • 7.2. Product Development Activity
  • 7.3. Profiles of Products in Late - Stage Development

8. Indication Specific Overview: Alzheimer's Disease

  • 8.1. Disease Overview and Epidemiology
  • 8.2. Product Development Activity
  • 8.3. Profiles of Products in Late - Stage Development

9. Trends in Clinical Trials of Neuroimmunology Drugs

  • 9.1. Geographical Locations of Ongoing Clinical Trials
  • 9.2. Ongoing Clinical Trials by Different Phases and Sponsor Type
  • 9.3. Indications Being Evaluated in Ongoing Clinical Trials
  • 9.4. Combination Therapy Trends in Ongoing Clinical Trials
  • 9.5. Unmet Needs Within Neuroimmunology

10. Appendix

  • 10.1. Sources
  • 10.2. Primary Research
  • 10.3. About the Authors
  • 10.4. About GlobalData
  • 10.5. Contact Us
  • 10.6. Disclaimer
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