Cover Image

Remicade(潰瘍性大腸炎) - 預測與市場分析

Remicade (Ulcerative Colitis) - Forecast and Market Analysis to 2022

出版商 GlobalData 商品編碼 300574
出版日期 內容資訊 英文 51 Pages
Back to Top
Remicade(潰瘍性大腸炎) - 預測與市場分析 Remicade (Ulcerative Colitis) - Forecast and Market Analysis to 2022
出版日期: 2014年02月28日 內容資訊: 英文 51 Pages



2012年到2022年潰瘍性大腸炎(UC)治療藥市場,預測將在Johnson & Johnson(Simponi)、武田藥品工業(Entyvio)的加入下大幅成長,主要國家(美國、歐盟五國、日本、加拿大)預計接受生技藥品治療的患者數將會增加。此外由於UC的暢銷藥物(Remicade,Humira)在美國專利到期,生技仿製藥的發售有影響市場的可能性。


第1章 目錄

第2章 簡介

第3章 疾病概要

  • 病因·病理生理學
  • 症狀

第4章 疾病的管理

  • 診斷和治療概要

第5章 競爭評估

  • 概要
  • 策略性競爭企業的評估

第6章 Remicade(infliximab)

  • 概要
  • 功效
  • 安全性
  • SWOT分析
  • 預測

第7章 附錄


Product Code: GDHC345DFR

During the forecast period from 2012-2022, the growth of the UC market will be driven largely by the entry of Johnson & Johnson's (J&J's) Simponi and Takeda's Entyvio, which will lead to an increase in the overall number of patients being treated with biologics in the US, 5EU, Japan, and Canada. Another key event affecting the UC market is the anticipated launch of biosimilars, given that the patent expiry of the UC blockbusters, Remicade and Humira are set to expire in the US in 2018 and 2016, respectively.

Remicade (infliximab) is a TNF-a inhibitor that was originally developed by Centocor Ortho Biotech, which is now Janssen Biotech, a subsidiary of J&J. Upon the onset of intestinal inflammation in IBD, a rather aggravated immune response is initiated that is skewed towards a specific T-cell phenotype. This T-cell group (Th1) is attracted to the site of inflammation, where additional white blood cells are recruited. Th1 cells produce large amounts of an inflammatory protein called INF-?, which, in turn, induces the production of the pro-inflammatory cytokine TNF-a in both local and recruited macrophages, as well as in the intestinal epithelial cells


  • Overview of Ulcerative Colitis, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
  • Detailed information on Remicade including product description, safety and efficacy profiles as well as a SWOT analysis.
  • Sales forecast for Remicade for the top ten countries from 2012 to 2022.
  • Sales information covered for the US, France, Germany, Italy, Spain, the UK, Japan, Canada, China and India.

Reasons to buy

  • Understand and capitalize by identifying products that are most likely to ensure a robust return
  • Stay ahead of the competition by understanding the changing competitive landscape for Ulcerative Colitis
  • Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
  • Make more informed business decisions from insightful and in-depth analysis of Remicade performance
  • Obtain sales forecast for Remicade from 2012-2022 in the top ten countries (the US, France, Germany, Italy, Spain, the UK, Japan, Canada, China and India)

Table of Contents

1. Table of Contents

  • 1.1. List of Tables
  • 1.2. List of Figures

2. Introduction

  • 2.1. Catalyst
  • 2.2. Related Reports
  • 2.3. Upcoming Related Reports

3. Disease Overview

  • 3.1. Etiology and Pathophysiology
    • 3.1.1. Etiology
    • 3.1.2. Pathophysiology
  • 3.2. Symptoms
    • 3.2.1. Quality of Life

4. Disease Management

  • 4.1. Diagnosis and Treatment Overview
    • 4.1.1. Diagnosis
    • 4.1.2. Treatment Guidelines and Leading Prescribed Drugs
    • 4.1.3. Clinical Practice

5. Competitive Assessment

  • 5.1. Overview
  • 5.2. Strategic Competitor Assessment

6. Remicade (infliximab)

  • 6.1. Overview
  • 6.2. Efficacy
  • 6.3. Safety
  • 6.4. SWOT Analysis
  • 6.5. Forecast

7. Appendix

  • 7.1. Bibliography
  • 7.2. Abbreviations
  • 7.3. Methodology
  • 7.4. Forecasting Methodology
    • 7.4.1. Diagnosed UC Patients
    • 7.4.2. Percent Drug-Treated Patients
    • 7.4.3. General Pricing Assumptions
    • 7.4.4. Individual Drug Assumptions
    • 7.4.5. Generic Erosion
  • 7.5. Physicians and Specialists Included in This Study
  • 7.6. Primary Research. Prescriber Survey
  • 7.7. About the Authors
    • 7.7.1. Author
    • 7.7.2. Global Head of Healthcare
  • 7.8. About GlobalData
  • 7.9. Disclaimer

List of Tables

  • Table 1: Genetic Factors That Confer a Predisposition to UC
  • Table 2: Typical Symptoms of UC
  • Table 3: Truelove and Witts UC Severity Index
  • Table 4: UCDAI
  • Table 5: Treatment Guidelines for UC Used in the 10MM
  • Table 6: Most Commonly Prescribed Drugs for UC by Class in the 10MM, 2013
  • Table 7: Leading Treatments for UC, 2014
  • Table 8: Product Profile - Remicade
  • Table 9: Remicade SWOT Analysis, 2014
  • Table 10: Global Sales Forecasts ($m) for Remicade, 2012-2022
  • Table 11: Physicians Surveyed, By Country

List of Figures

  • Figure 1: Cellular Mechanisms Involved in the Pathogenesis of UC
  • Figure 2: UC Disease Management Flowchart
Back to Top