NEWS: 公告在東京證券交易所JASDAQ標準市場新上市

市場調查報告書

外排體的全球市場:2020-2027

Global Exosomes Market - 2020-2027

出版商 DataM Intelligence 商品編碼 962193
出版日期 按訂單生產 內容資訊 英文
商品交期: 請詢問到貨日
價格
外排體的全球市場:2020-2027 Global Exosomes Market - 2020-2027
出版日期: 按訂單生產內容資訊: 英文
簡介

外排體是培養物中大多數細胞分泌的內吞作用的小膜囊泡,是在中間內吞作用室多囊泡(MVB)與祖細胞膜融合後產生的。它是一種納米大小的囊泡,可以在有或沒有直接細胞間接觸的情況下轉移DNA,microRNA,非編碼RNA和脂質,並且是細胞內通訊的新手段。

外排體通過各種細胞(包括癌細胞)的胞吐作用分泌,然後被靶細胞吸收,信息通過表面蛋白信號傳導和生物分子(如脂質和核酸)遷移而傳遞。外排體的細胞間通訊在調節細胞和生理過程中起著重要作用。

從牛奶中提取的外排體可用於治療肺癌和乳腺癌的分子。來自身體特定部位的外排體因其體積小,獨特的特性和克服生物障礙的能力而成為抗癌疫苗的有希望的候選者。

市場擴展的驅動力是諸如癌症患病率增加,外排體分離和分析程序的技術進步以及外排體的先進應用等因素。根據世界衛生組織(WHO)2012年的報告,新癌症病例數為1400萬,在未來20年中將增長約70%。

該報告調查了全球外排體市場,並提供了有關市場動態,行業分析,產品,應用,最終用戶,區域分析,競爭狀況,公司概況等信息。

目錄

第1章調查方法和範圍

第2章市場定義和概述

第3章執行摘要

第4章市場動態

  • 影響市場的因素
    • 促進因素
    • 抑制因素
  • 影響分析
  • 市場機會

第5章行業分析

  • 波特的五力分析
  • 供應鏈分析
  • 監管分析
  • 價格分析
  • 產品分析

第6章按產品劃分的市場

  • 簡介
  • 市場規模和同比增長率分析
  • 市場吸引力指數
    • 試劑盒和試劑*
    • 設備
    • 其他

第7章按應用劃分的市場

  • 簡介
  • 市場規模和同比增長率分析
  • 市場吸引力指數
    • 癌症
    • 癌症以外

第8章最終用戶的市場

  • 簡介
  • 市場規模和同比增長率分析
  • 市場吸引力指數
    • 診斷
    • 治療
    • 醫院,臨床實驗室
    • 其他

第9章區域市場

  • 簡介
  • 市場規模和同比增長率分析
  • 市場吸引力指數
  • 北美
  • 歐洲
  • 南美洲
  • 亞太地區
  • 中東/非洲

第10章競爭情況

  • 競爭情景
  • 市場定位/佔有率分析
  • 併購分析

第11章公司簡介

  • STARTEK Health*
  • Diagenode Inc.
  • Fujifilm Holdings Corporation
  • Hitachi Chemical Diagnostics Inc.
  • Lonza
  • MBL International
  • Miltenyi Biotec
  • Novus Biologicals
  • Qiagen
  • Thermo Fisher Scientific Inc
  • List is not exhaustive

第12章主要調查結果

第13章全球外來體市場

目錄

Market Overview

Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture, and are created upon the fusion of the multivesicular body (MVB), an intermediate endocytic compartment, with the plasma membrane. They are nano-sized vesicles capable of transferring DNAs, micro RNAs, non-coding RNAs, and lipids, with or without direct cell-to-cell contact, which represents a novel method of intracellular communication. Exosomes are secreted via exocytosis by a variety of cell types, including cancer cells, and subsequently are taken up by target cells, where they communicate information via surface protein signaling as well as through the transfer of lipids, nucleic acids, and other biomolecules. Intercellular communication by exosomes plays a critical role in the regulation of cellular and physiological processes

Exosomes extracted from cow milk is being used for the delivery of therapeutic molecules against lung and breast cancers. Exosomes derived from specific sites of the body are promising candidates for anti-cancer vaccines, due to the enhanced passive targeting, owing to its small size, indigenous nature, and the ability to cross the biological barriers. Thus, the increase in the cancer cases in the hospitals directly increases the demand for exosomes in diagnosis as well as therapeutics.

Market Dynamics:

The market is driven is the increasing prevalence of cancer, technological advancements in exosomes isolation and analytical procedures, and increasing advanced applications of exosomes. The growing prevalence of cancer patients has a direct impact on the increased demand for the exosomes market.

According to the 2012 report of the World Health Organization (WHO), there were 14 million new cases of cancer, and this is expected to rise by about 70% over the next two decades. In the United States, as per the National Cancer Institute report of 2018, an estimated 1.7 million new cases of cancer were diagnosed in the country and nearly 0.6 million patients died due to cancer. This factor will drive the growth of market in the forecast period.

Exosomes are of special interest in the field of medicine. Their ability to stimulate immune responses, for instance, has made them of particular interest in the development of novel approaches to vaccination, including the development of vaccines to treat certain cancers. In addition, because exosomes are found in body fluids such as blood, urine, and cerebrospinal fluid, they are promising biomarkers for the detection of disease.

Exosomes loading with drugs have been widely used for various diseases treatment. In a research, exosomes containing the anti-inflammatory small molecule compound curcumin have been shown to protect mice from brain inflammation induced by lipopolysaccharides. The incorporation of curcumin in exosomes improved its solubility, prolonged circulation time, retained drug therapy activity, and improved brain delivery. During tumor treatment, tumor exosomes loaded with anti-tumor drugs can effectively ensure drug maintain their native property and promote drug transport to target tumor tissue. This factor will drive the growth of market in the forecast period.

Exosomes are perceived to be used as carriers between different locations of body. Exosomes are secreted by all types of cells and are also found abundantly in the body fluids such as saliva, blood, urine and breast milk.

However, a number of technical difficulties need to be addressed for the successful implementation of exosomes in various applications, this factor will hamper the market during the forecast period. Some of the major difficulties include optimization of purification, increasing the homogeneity of exosomes, and efficient transfection strategies.

The recent outbreak of the COVID-19 pandemic is likely to act as a major restraint to market. Most diagnostic centers are busy in the COVID-19 test which will delay its therapeutics uses in the centers. This factor will hinder the growth of the market in the forecast period.

Segment Analysis

The global medical coding market is segmented based on application by cancer applications, and non-cancer applications. The cancer applications is further sub segmented into lung cancer, breast cancer, prostate cancer, colorectal cancer and others. Lungs cancer held the largest market share due to increasing prevalence of lung cancer. The need for more efficient diagnostic systems is due to the fact that only 15% of the lung cancer cases get diagnosed while the remaining undiagnosed cancer cases develop into more aggressive forms, which reduces the 5-year survival rate to only 4% in these patients that are detected with late-stage lung cancer.

According to Centers for Disease Control and Prevention (CDC), lung cancer is the primary cause of cancer death and the second most common cancer. According to American Cancer Society in U.S. approximately 195,000 people are suffering from lungs cancer every year and the mortality rate accounts for approximately 135,000.

Smoking, environmental pollution, environmental pollution, rising cases of infections, growing rates of early detection and awareness are the leading factor of lungs cancer and drives the growth of the segment in the forecast period.

The colorectal cancer segment is expected to have positive market growth in the forecast period. According to American Cancer Society, in United States when men and women are considered individually colorectal cancer is the third prominent cause of cancer-related mortality, and the second prominent cause when both are combined. Increasing adoption of western diet which are high in fat and low in fiber is expected to boost the growth of segment over the forecast period.

According to National Cancer Institute, in 2016, an estimated 134,490 people in the United States will be diagnosed with colorectal cancer and 49,190 people will die from it. Due to increase in screening of colorectal cancer and changes in some risk factors such as a decline in smoking and consumption of alcohol is decreasing the rate of new colorectal cancer cases and deaths among adults aged 50 years and above.

Further, the market is also classified based on end user as diagnostics, therapeutics, hospitals & clinical testing laboratories and others. The therapeutics segment is held the largest market share. Exosomes have promising potential to be as a vehicle for drug delivery as they have natural material transportation properties, the capability of intrinsic long-term circulation, and high biocompatibility, which are the most suitable factors for the delivery of a variety of proteins, chemicals, and nucleic acids. According to a few research studies, exosomes have generated positive results as mediators of the intercellular communication, potentially delivering the functional proteins, mRNA transcripts, and miRNAs to cells throughout the body.

Exosomes which are derived from some types of cells such as dendritic and mesenchymal stem cells have potential therapeutic properties and are biocompatible and efficient agents against various disorders such as organ injury. This factor will drive the growth of market in the forecast period.

Geographical Presentation

By region, the exosomes market is segmented into North America, South America, Europe, Asia-Pacific, Middle-East, and Africa. Among all of the regions, North America dominated the global exosomes market and is expected to grow at the highest CAGR during the forecast period due to better healthcare infrastructure, effective government policies, a huge base of multinational companies, and high awareness among people about diagnostics and healthcare.

A large number of government-funded research studies have been conducted, regarding the role of drugs using exosomes in several kinds of cancers, such as melanoma, breast cancer, lung cancer, and pancreatic cancer, among others.

Companies, like Merck and Exosome Diagnostic, have sponsored and collaborated with several universities, such as Yale University and Michigan State University, to conduct clinical trials in the United States. Furthermore, these ventures are very well supported by government funding. These factors will drive the growth of market in the region.

For instance, in March 2017, researchers at the Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine received two grants from the Sohn Conference Foundation for R&D in isolation and characterization of tumor-derived exosomes to study cancer occurrence in children.

The Asia-Pacific region is expected to have third-largest share due to the higher growth rate is attributed to immense potential identified in emerging economies such as China and India. Competitive strategies adopted by players to carry out R&D activities in this sector. The growth of the various pharmaceutical companies in the region is also driving the growth of the market in the forecast period.

Competitive Analysis

The exosomes market is highly competitive with the presence of several international and local markets. Product diversification, revenue generation, and opportunities intensify the market competition Diagenode Inc., Fujifilm Holdings Corporation, Hitachi Chemical Diagnostics Inc., Lonza, MBL International, Miltenyi Biotec, NX Pharmagen, Novus Biologicals, Qiagen, Thermo Fisher Scientific Inc. are the leading market players with significant market share. The major players are using product development, novel product launches, market expansion, and product diversification strategies for holding their position in the market.

The companies are entering into collaborations, mergers, strategic partnerships, and acquisitions to expand their presence and meet the rising demand for the exosomes across the globe.

For instance, in 2018, Thermo Fisher Scientific expanded its presence in the US by opening the U.S. Precision Medicine Science Center (PMSC) in Cambridge. This center is aimed to develop analytical workflows to generate precise molecular profiles of patients.

In 2018, Lonza established its Collaborative Innovation Center (CIC) in the new Life Science Park in the outskirts of Haifa, Israel. This center focuses on R&D projects of Lonza's Pharma & Biotech segment.

Why Purchase the Report?

  • Visualize the composition of the global exosomes market products in terms of product, application and end-user and highlighting the critical commercial assets and players.
  • Identify commercial opportunities in the global exosomes market by analyzing trends and co-development deals.
  • Excel data sheet with thousands of data points of global exosomes market level 4/5 segmentation.
  • PDF report with the most relevant analysis cogently put together after exhaustive qualitative interviews and in-depth market study.
  • *The global exosomes market report will provide access to approximately 61 market data tables, 57 figures, and 200 pages

Target Audience2022

  • Industry Investors/Investment Bankers
  • Suppliers/Buyers
  • Education & Research Institutes
  • Manufacturers
  • Research Professionals
  • Emerging Companies
  • Distributors

Table of Contents

1. Global Exosomes Market Methodology and Scope

  • 1.1. Research Methodology
  • 1.2. Research Objective and Scope of the Report

2. Global Exosomes Market - Market Definition and Overview

3. Global Exosomes Market - Executive Summary

  • 3.1. Market Snippet by Product
  • 3.2. Market Snippet by Application
  • 3.3. Market Snippet by End-User
  • 3.4. Market Snippet by Region

4. Global Exosomes Market Dynamics

  • 4.1. Market Impacting Factors
    • 4.1.1. Drivers
      • 4.1.1.1. Increasing Prevalence of Cancer
      • 4.1.1.2. Increasing Advanced Applications of Exosomes
    • 4.1.2. Restraints
      • 4.1.2.1. Technical Difficulties with the Implementation and Usage of Exosomes
  • 4.2. Impact Analysis
  • 4.3. Opportunity

5. Global Exosomes Market - Industry Analysis

  • 5.1. Porter's Five Forces Analysis
  • 5.2. Supply Chain Analysis
  • 5.3. Regulatory Analysis
  • 5.4. Pricing Analysis
  • 5.5. Product Analysis

6. Global Exosomes Market - By Product

  • 6.1. Introduction
  • 6.2. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
  • 6.3. Market Attractiveness Index, By Product
    • 6.3.1. Kits and Reagents *
      • 6.3.1.1. Introduction
      • 6.3.1.2. Market Size Analysis, US$ Mn, 2016-2025 and Y-o-Y Growth Analysis (%), 2019-2027
    • 6.3.2. Instruments
    • 6.3.3. Others

7. Global Exosomes Market - By Application

  • 7.1. Introduction
  • 7.2. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
  • 7.3. Market Attractiveness Index, By Application
    • 7.3.1. Cancer Applications
      • 7.3.1.1. Lung Cancer
      • 7.3.1.1.1. Introduction
      • 7.3.1.1.2. Market Size Analysis, US$ Mn, 2016-2025 and Y-o-Y Growth Analysis (%), 2019-2027
      • 7.3.1.2. Breast Cancer
      • 7.3.1.3. Prostate Cancer
      • 7.3.1.4. Colorectal Cancer
      • 7.3.1.5. Other
    • 7.3.2. Non-Cancer Applications

8. Global Exosomes Market - By End-User

  • 8.1. Introduction
  • 8.2. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-User
  • 8.3. Market Attractiveness Index, By End-User
    • 8.3.1. Diagnostics
      • 8.3.1.1. Introduction
      • 8.3.1.2. Market Size Analysis, US$ Mn, 2016-2025 and Y-o-Y Growth Analysis (%), 2019-2027
    • 8.3.2. Therapeutics
    • 8.3.3. Hospitals & Clinical Testing Laboratories
    • 8.3.4. Others

9. Global Exosomes Market - By Region

  • 9.1. Introduction
  • 9.2. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Region
  • 9.3. Market Attractiveness Index, By Region
  • 9.4. North America
    • 9.4.1. Introduction
    • 9.4.2. Key Region-Specific Dynamics
    • 9.4.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
    • 9.4.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
    • 9.4.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-User
    • 9.4.6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
      • 9.4.6.1. U.S.
      • 9.4.6.2. Canada
      • 9.4.6.3. Mexico
  • 9.5. Europe
    • 9.5.1. Introduction
    • 9.5.2. Key Region-Specific Dynamics
    • 9.5.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
    • 9.5.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
    • 9.5.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-User
    • 9.5.6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
      • 9.5.6.1. Germany
      • 9.5.6.2. U.K.
      • 9.5.6.3. France
      • 9.5.6.4. Rest of Europe
  • 9.6. South America
    • 9.6.1. Introduction
    • 9.6.2. Key Region-Specific Dynamics
    • 9.6.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
    • 9.6.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
    • 9.6.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End User
    • 9.6.6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
      • 9.6.6.1. Brazil
      • 9.6.6.2. Argentina
      • 9.6.6.3. Rest of South America
  • 9.7. Asia Pacific
    • 9.7.1. Introduction
    • 9.7.2. Key Region-Specific Dynamics
    • 9.7.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
    • 9.7.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
    • 9.7.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-User
    • 9.7.6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
      • 9.7.6.1. China
      • 9.7.6.2. India
      • 9.7.6.3. Japan
      • 9.7.6.4. Australia
      • 9.7.6.5. Rest of Asia Pacific
  • 9.8. Middle East and Africa
    • 9.8.1. Introduction
    • 9.8.2. Key Region-Specific Dynamics
    • 9.8.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
    • 9.8.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
    • 9.8.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End User

10. Global Exosomes Market Competitive Landscape

  • 10.1. Competitive Scenario
  • 10.2. Market Positioning/Share Analysis
  • 10.3. Mergers and Acquisitions Analysis

11. Global Exosomes Market Company Profiles

  • 11.1. STARTEK Health*
    • 11.1.1. Company Overview
    • 11.1.2. Product Portfolio and Description
    • 11.1.3. Key Developments
    • 11.1.4. Financial Overview
  • 11.2. Diagenode Inc.
  • 11.3. Fujifilm Holdings Corporation
  • 11.4. Hitachi Chemical Diagnostics Inc.
  • 11.5. Lonza
  • 11.6. MBL International
  • 11.7. Miltenyi Biotec
  • 11.8. Novus Biologicals
  • 11.9. Qiagen
  • 11.10. Thermo Fisher Scientific Inc
  • List is not exhaustive

12. Global Exosomes Market - Premium Insights

13. Global Exosomes Market - DataM

  • 13.1. Appendix
  • 13.2. About Us and Services
  • 13.3. Contact Us