市場調查報告書
商品編碼
1138308
全球蛋白質檢測量化市場-2022-2029Global Protein Detection Quantification Market - 2022-2029 |
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全球蛋白質檢測量化市場的增長受到某些因素的推動,例如創傷數量的增加。此外,在分子水平上了解慢性病和開發治療方案的需求日益增長,也是推動市場增長的主要因素之一。
在分子水平上了解慢性病、開發治療解決方案和鼓勵這些組織為其研發項目提供資金的需求日益增長,預計將在預測期內推動市場發展。
美國國家癌症研究所 (NCI) 的公共衛生基因組學將個性化醫學和基因組學推進到公共衛生癌症研究中,以減輕全球癌症負擔。
政府通過資助蛋白質組學行業來鼓勵研究活動。因此,蛋白質檢測和量化市場預計將在未來幾年顯著增長。人類蛋白質組組織、國家癌症研究所 (NCI) 和基因組健康公司等組織的存在促進了資金支持蛋白質組學領域的研發和產品開發活動。
此外,為闡明生物製劑的物理和化學降解途徑的機製而進行的蛋白質組學研究有望促進進展。此外,下一代蛋白質濃度估計技術的發展有望推動具有潛力的市場。
此外,通過蛋白質組學和基因組學研究開發的各種候選生物標誌物可以成為製造更安全、更有效藥物的預測指標。在探索階段,基於質譜的蛋白質組學分析可以識別與疾病進展相關的特定機制相關且受藥物治療影響的候選者。
儘管簡化蛋白質估計的技術不斷進步,但技術和檢測的高成本預計會限制這些檢測和技術在某些情況下的實用性。例如,通常用於功能蛋白質組學的質譜 (MS) 被認為對研究人員來說既昂貴又耗時。靶向 MS 需要針對每個靶標定制抗體,以進行□的免疫親和富集。靶向 MS 還需要針對每個靶點定制抗體,以通過免疫親和性富集□,這既昂貴又耗時。
據推測,在分子水平上了解各種慢性疾病和開發治療方法的需求日益增加,這將支持對這些組織的研發計劃的投資。此外,美國國家癌症研究所 (NCI) 公共衛生基因組學正在幫助將基因組學和個性化醫學整合到公共衛生癌症研究中,以減輕全球癌症負擔。
COVID-19 的爆發對市場的增長產生了負面影響。中心將關閉,實驗室將因 COVID-19 測試而不堪重負,從而在預測期內阻礙市場增長。
行業分析
全球蛋白質檢測量化市場根據波特五力分析、供應鏈分析、監管分析和價格分析等各種行業因素對市場進行深入分析。
全球蛋白質檢測量化市場報告提供了大約 40 多個市場數據表、45 多個圖表和 180 頁的結構。
Protein detection quantification market size was valued at US$ 2.25 billion in 2021 and is estimated to reach US$ XX million by 2029, growing at a CAGR of 9.60% during the forecast period (2022-2029).
Detection and subsequent quantification of proteins is a vital step in the understanding of post-translational modifications. It assists in understanding the functions of complex networks of peptides for use in medicine and cell biology. Increased demand for quantification of protein in laboratories that are engaged with various activities. These laboratories' activities range from drug dosing and clinical diagnostic testing to protein characterization and are likely to influence industrial growth in the years to come.
The global protein detection quantification market growth driven by certain factors such as by rising number of traumatic injuries drives the market. The market growth is also majorly driven by the increasing need to understand chronic diseases at a molecular level and develop therapeutic solutions to encourage these organizations to fund research and development programs are among the key factors driving the market growth.
Increasing need to understand chronic diseases at a molecular level and develop therapeutic solutions to encourage these organizations to fund research and development programs., is expected to drive the market during the forecast period
Public Health Genomics at the National Cancer Institute (NCI) promotes personalized medicine and genomics into public health cancer research to reduce cancer burden across the globe.
Governments are encouraging research activities by raising funds in the proteomics industry. Thus, the protein detection and quantification market are anticipated to grow significantly in the coming years. The presence of organizations such as the Human Proteome Organization, National Cancer Institute (NCI), and Genomic Health Inc. promotes funding to support R&D and product development exercises about the field of proteomics.
Furthermore, proteomic studies carried out for finding the mechanism of physical and chemical degradation pathways of biologics are anticipated to propel progress. In addition to advancements, the development of next-generation protein concentration estimation techniques is expected to drive the market with potential avenues.
Besides, various candidate biomarkers developed through proteomics and genomics research can serve as predictive indexes for producing safer and more effective drugs. In the discovery stage, differential proteomic analysis with the help of mass spectrometry enables the recognition of candidates linked with a specific mechanism relevant to disease progression and affected by drug treatment.
Although technological advancements continue to take place for simplification protein estimation, the high cost of technology and assays are anticipated to restrict the usage of these assays and technologies under certain circumstances. For instance, Mass Spectroscopy (MS), which is often used for functional proteomics, is considered expensive and slow by researchers. In targeted MS, custom antibodies are required for each target to perform immunoaffinity enrichment of peptides. This process is observed to be expensive as well as lengthy.
The increasing need to comprehend various chronic diseases at a molecular level and then develop therapeutic solutions is estimated to support these organizations in investing in research and development programs. Besides, Public Health Genomics at the National Cancer Institute (NCI) boosts the incorporation of genomics and personalized medicine into the research of public health cancer to diminish the burden of cancer all over the world.
The COVID-19 outbreak has negatively affected the growth of the market. The centers are closed, and the laboratories are busy with the COVID-19 test, which will hamper the forecast period's market growth.
Industry Analysis
The global protein detection quantification market provides in-depth analysis of the market based on various industry factors such as porter's five force analysis, supply chain analysis, regulatory analysis, pricing analysis etc.
The colorimetric assays segment is expected to grow at the fastest CAGR during the forecast period (2022-2029)
The colorimetric assays segment held the largest market share due to its convenience rate and wide availability of the reagents for its implementation. Colorimetric assays are based on the binding of a specific dye to the rhamnolipid.
Colorimetric assays help distinguish a particular enzyme from another, quantitate catalytic activity, and inhibit this activity, generate proliferative and toxicity profiles, and even determine the concentration of proteins in solution. They are a simple and convenient way to visualize biological processes.
In colorimetric assays, the substrate is converted by the enzyme into a soluble, colored reaction product. This allows precise determination of the enzyme activity by optical density, such as peroxidase activity is measured by reducing the substrate in the presence of hydrogen peroxide, producing a soluble chromogen that is measured with a spectrophotometer. These colorimetric assay methods are often used for microtiter plate-based ELISAs in combination with an automated spectrophotometer.
The testing of protein concentration was done using citrate buffer with tetra bromophenol blue, and the change of color observed was from yellow to blue. These are well-known colorimetric assays commonly used in urine analysis. The different chemicals and enzymes were spotted at the last step of the device fabrication and left to dry in the detection zones. Similar glucose and protein tests were tried on devices patterned with different methods.
Kinases and phosphatases mediate various cellular processes like metabolism, gene transcription and translation, protein-protein interactions, and apoptosis through protein phosphorylation and dephosphorylation. For this reason, many different technologies, including various colorimetric assays, exist to detect these enzymes and their activity. This factor will drive the growth of the market in the forecast period.
North America region holds the largest market share of the global protein detection quantification market
North America dominated the global protein detection quantification market and is expected to grow at the highest CAGR during the forecast period. The region is estimated to be driven by the US mainly due to leading market players in the country and a well-established healthcare framework in the US. A combination of factors such as developed infrastructure, an increase in R&D investment, and growing cases of various diseases in the region are the factors attributed to the market growth in the U.S.
The global protein detection quantification market is highly competitive with the presence of several international and local markets. Product diversification, revenue generation, and opportunities intensify Merck & Co., Inc., Danaher, RayBiotech, Inc., Innovate, Shimadzu Corporation, and PerkinElmer Inc, Bio-Rad Laboratories, Inc., Thermo Fisher Scientific, and GE Healthcare are the leading market players with significant market share. The major players are using product development, novel product launches, market expansion, and product diversification strategies for holding their position in the market.
The companies enter into collaborations, mergers, strategic partnerships, and acquisitions to expand their presence and meet the rising demand for protein detection quantification worldwide. For instance, In August 2020, Oil-Dri Corporation of America, the leading manufacturer of sorbent minerals, parent company to Amlan International, announces that the European Patent Office has issued Patent EP 2906238. The patent covers the unique formulation of two existing mineral-based natural feed additives, Varium for poultry and NeoPrime for swine, that help global animal protein producers thrive in an era of antibiotic-free production.
Bio-Rad Laboratories
Overview: Bio-Rad Laboratories, Inc. is an American company that continued to produce innovative and useful products in the healthcare industry that assist life science researchers in accelerating the discovery process, and medical diagnostic labs obtain faster better results.
Product Portfolio: DC Protein Assay Reagents Package- Reagent pack for colorimetric assays, includes 250 ml alkaline copper tartrate, 2 L dilute Folin reagent, 5 ml surfactant solution; 450 assays.
The global protein detection quantification market report would provide an access to an approx. 40+ market data table, 45+ figures and 180 pages.