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市場調查報告書

蛋白質檢測、定量檢測的全球市場:2020-2027年

Global Protein Detection Quantification Market - 2020-2027

出版商 DataM Intelligence 商品編碼 955845
出版日期 內容資訊 英文
商品交期: 最快1-2個工作天內
價格
蛋白質檢測、定量檢測的全球市場:2020-2027年 Global Protein Detection Quantification Market - 2020-2027
出版日期: 2020年09月04日內容資訊: 英文
簡介

全球蛋白質檢測、定量檢測市場成長,由外傷的增加促進。還有,美國國立癌症研究所(NCI)的公共衛生基因學,為了減少全球的癌症負擔,推動公共衛生癌症研究與個人化醫療和基因學的整合。政府在蛋白質組學領域籌措資金,獎勵研究活動,蛋白質檢測、定量檢測市場今後數年預計大幅度成長。

本報告提供全球蛋白質檢測、定量檢測市場相關調查,市場概要,各市場區隔及各地區的市場規模的預測,主要企業的簡介,競爭情形分析等系統性資訊。

目錄

第1章 全球蛋白質檢測、定量檢測市場:調查手法、調查範圍

  • 調查手法
  • 調查目的、範圍

第2章 全球蛋白質檢測、定量檢測市場:市場定義和概要

第3章 全球蛋白質檢測、定量檢測市場:摘要整理

  • 市場明細:各技術
  • 市場明細:各產品
  • 市場明細:各應用領域
  • 市場明細:各終端用戶
  • 市場明細:各地區

第4章 全球蛋白質檢測、定量檢測市場:市場動態

  • 市場影響要素
    • 促進因素
    • 阻礙因素
  • 影響分析
  • 市場機會

第5章 全球蛋白質檢測、定量檢測市場:產業分析

  • 波特的五力分析
  • 供應鏈分析
  • 法規分析
  • 價格分析
  • 產品分析
  • 售後服務分析

第6章 全球蛋白質檢測、定量檢測市場:各技術

  • 簡介
  • 市場規模分析、與前一年同期比較成長率分析:各技術
  • 市場魅力指數:各技術
    • 比色分析
    • 免疫學的方法
    • 層析法
    • 質譜分析
    • 分光計
    • 其他

第7章 全球蛋白質檢測、定量檢測市場:各產品

  • 簡介
  • 市場規模分析、與前一年同期比較成長率分析:各產品
  • 市場魅力指數:各產品
    • 套件&試劑/消耗品
    • 樂器
    • 服務

第8章 全球蛋白質檢測、定量檢測市場:各應用領域

  • 簡介
  • 市場規模分析、與前一年同期比較成長率分析:各應用領域
  • 市場魅力指數:各應用領域
    • 藥物研發與開發
    • 臨床診斷
    • 其他

第9章 全球蛋白質檢測、定量檢測市場:各終端用戶

  • 簡介
  • 市場規模分析、與前一年同期比較成長率分析:各終端用戶
  • 市場魅力指數:各終端用戶
    • 學術調查機關
    • 生物科技及醫藥品企業
    • CRO
    • 其他

第10章 全球蛋白質檢測、定量檢測市場:各地區

  • 簡介
    • 市場規模分析、與前一年同期比較成長率分析:各地區
    • 市場魅力指數:各地區
  • 北美
    • 簡介
    • 主要地區具體動態
    • 市場規模分析、與前一年同期比較成長率分析:各技術
    • 市場規模分析、與前一年同期比較成長率分析:各產品
    • 市場規模分析、與前一年同期比較成長率分析:各應用領域
    • 市場規模分析、與前一年同期比較成長率分析:終端用戶
    • 市場規模分析、與前一年同期比較成長率分析:各國
  • 歐洲
  • 南美
  • 亞太地區
  • 中東、非洲

第11章 全球蛋白質檢測、定量檢測市場:競爭情形

  • 競爭模式
  • 市場定位/佔有率分析
  • 合併和收購分析

第12章 企業簡介

  • Merck & Co., Inc.
    • 企業概要
    • 組合、說明
    • 主要的焦點
    • 財務概要
  • Danaher
  • RayBiotech, Inc.
  • Inanovate, Inc.
  • 島津製作所
  • PerkinElmer Inc
  • Bio-Rad Laboratories, Inc.
  • Thermo Fisher Scientific
  • GE Healthcare
  • Hartalega Holdings Bhd

第13章 全球蛋白質檢測、定量檢測市場:重要考察

第14章 全球蛋白質檢測、定量檢測市場:DataM

  • 附錄
  • 關於本公司、服務
  • 諮詢方式
目錄

Market Overview

Detection and subsequent quantification of proteins is a vital step in the understanding of post-translational modifications. It assists in the understanding of the functions of complex networks of peptide for use in medicine and cell biology. Increased demand for quantification of protein in laboratories that are engaged with various activities. The activities in these laboratories range from drug dosing and clinical diagnostic testing to protein characterization and are likely to influence the industrial growth in the years to come. Factors such as these are likely to propel expansion of the global protein detection and quantification market.

Furthermore, various candidate biomarkers developed through proteomics and genomics research have the potential to serve as predictive indexes for producing safer and more effective drugs. In the discovery stage, differential proteomic analysis with the help of mass spectrometry enables the recognition of candidates which are linked with a specific mechanism relevant to disease progression and affected by drug treatment.

Incorporation of informative biomarkers as predictive tools in clinical trials is increasingly viewed for not only enabling smarter decisions but also as a resource investment for the development of potential diagnostics. The aforementioned fact is anticipated to drive the clinical diagnostics segment with the fastest rate

Selection of an appropriate technology out of a large number of available methods of quantitation for the kind of protein to be detected and its concentration in the sample remains an important step in biotechnology protocols.

Market Dynamics:

The market is driven is the rising number of traumatic injuries. The market growth is also majorly driven by the increasing need to understand chronic diseases at a molecular level and develop therapeutic solutions is expected to encourage these organizations to fund research and development programs. In addition, Public Health Genomics at the National Cancer Institute (NCI) promotes the integration of personalized medicine and genomics into public health cancer research in an attempt to reduce the burden of cancer across the globe.

Governments are encouraging the research activities by raising funds in the field of proteomics industry and thus the protein detection and quantification market is anticipated to grow at a significant pace in the coming years. The presence of organizations such as the Human Proteome Organization, National Cancer Institute (NCI), and Genomic Health Inc. promotes funding to support R&D and product development exercises pertaining to the field of proteomics.

Furthermore, proteomic studies carried out on for finding the mechanism of physical and chemical degradation pathways of biologics are anticipated to propel progress. In addition to advancements, the development of next-generation techniques for the protein concentration estimation is expected to drive the market with potential avenues.

In addition, various candidate biomarkers developed through proteomics and genomics research have the potential to serve as predictive indexes for producing safer and more effective drugs. In the discovery stage, differential proteomic analysis with the help of mass spectrometry enables the recognition of candidates which are linked with a specific mechanism relevant to disease progression and affected by drug treatment.

Although technological advancements continue to take place for simplification protein estimation, high cost of technology and assays are anticipated to restrict the usage of these assays and technologies under certain circumstances. For instance, Mass Spectroscopy (MS) which is often used for functional proteomics is considered expensive and slow by researchers. In targeted MS, custom antibodies are required for each target to perform immunoaffinity enrichment of peptides. This process is observed to be expensive as well as lengthy.

Increasing need to comprehend various chronic diseases at a molecular level and then come up with therapeutic solutions is estimated to support these organizations to invest in research and development programs. Besides, Public Health Genomics at the National Cancer Institute (NCI) boosts incorporation of genomics and personalized medicine into research of public health cancer in an effort to diminish the burden of cancer all over the world.

The COVID-19 outbreak has negatively affected the growth of the market. The centers are closed and the laboratories are busy in the COVID-19 test which will hamper the market growth in the forecast period.

Segment Analysis

The global protein detection quantification market is segmented based on technology by colorimetric assays, immunological methods, chromatography, mass spectrometry, spectroscopy instruments, others. The colorimetric assays segment held the largest market share due to its convenience rate and wide availability of the reagents for its implementation. Colorimetric assays are based on the binding of a specific dye to the rhamnolipid.

Colorimetric assays help to distinguish a particular enzyme from another, to quantitate catalytic activity, as well as inhibition of this activity, to generate proliferative and toxicity profiles, and even to determine the concentration of proteins in solution. They are a simple and convenient way to visualize biological processes.

In colorimetric assays, the substrate is converted by the enzyme into a soluble, colored reaction product. This allows precise determination of the enzyme activity by optical density such as peroxidase activity is measured by the reduction of the substrate in the presence of hydrogen peroxide, producing a soluble chromogen that is measured with a spectrophotometer. These colorimetric assay methods are often used for microtiter plate-based ELISAs in combination with an automated spectrophotometer.

The testing of protein concentration was done using citrate buffer with tetra bromophenol blue and the change of color observed was from yellow to blue. These are well known colorimetric assays commonly used in urine analysis. The different chemicals and enzymes were spotted at the last step of the device fabrication and left to dry in the detection zones. Similar glucose and protein tests were tried on devices patterned with different methods

Kinases and phosphatases mediate a variety of cellular processes like metabolism, gene transcription and translation, protein-protein interactions, and apoptosis, through protein phosphorylation and dephosphorylation. For this reason, many different technologies, including various colorimetric assays, exist to detect these enzymes and their activity. This factor will drive the growth of the market in the forecast period.

The chromatography segment is expected to have positive market growth due to the enable researchers for detection and monitoring changes in the biomarker concentration, down to a femtogram level, with scope to increase the limit of detection with further fine-tuning down the line.

Chromatography is the most widely used separation technique in chemical laboratories, where it is used in analysis, isolation and purification, and it is commonly used in the chemical process industry as a component of small and large-scale production. In terms of scale, at one extreme minute quantities of less than a nanogram are separated and identified during analysis, while at the other, hundreds of kilograms of material per hour are processed into refined products. It is the versatility of chromatography in its many variants that is behind its ubiquitous status in separation science, coupled with simplicity of approach and a reasonably well-developed framework in which the different chromatographic techniques operate.

Chromatography is essentially a physical method of separation in which the components of a mixture are separated by their distribution between two phases. This factor will drive the growth of the market in the forecast period.

Further, the market is also classified based on application as drug discovery and development, clinical diagnosis, others. The drug discovery and development segment is held the largest market share. The drug discovery and development is the processes involved, and how pharmaceutical chemists perform their chemistry using batch and flow chemistry systems. The process of bringing a new medicine to market is extremely challenging, costing an average of $2.6B and taking up to 12 years. It is therefore important for pharmaceutical companies to optimize the drug discovery and development process, to maximize the lifetime of the medicine before patents expire.

Drug discovery typically begins with target identification is selecting a biochemical mechanism involved in a disease condition. Up to 10,000 drug candidates are then put through a rigorous screening process to establish their interaction with the drug target. Once initial "hits" (drugs with activity against the target) are identified, a focused library of similar compounds will be synthesized to optimize interactions with the drug target; this is the process of library synthesis. This factor will drive the growth of the market in the forecast period.

The clinical diagnosis segment is expected to have positive market growth due to the growing incidence of infectious and chronic diseases, and increasing adoption of the automated platform. Infectious and chronic diseases are considered the leading causes of death, worldwide. According to the World Health Organization, lower respiratory infections remained the most deadly communicable diseases that caused 3.0 million deaths worldwide in 2016.

People with infectious diseases and chronic conditions are the most frequent users of healthcare and account for the majority of hospital admissions and clinical diagnostics done. These diseases account for the vast majority of healthcare spending. The average healthcare coverage costs for people with a chronic condition is five times higher than for those without such a condition.

The clinical diagnostics have been proved to be beneficial in chronic disease conditions since they are extremely valuable for disease prevention, detection, and management by influencing to make the correct clinical decision-making. This factor will drive the growth of the market in the forecast period.

Geographical Presentation

By region, the global protein detection quantification market is segmented into North America, South America, Europe, Asia-Pacific, Middle-East, and Africa. Among all of the regions, North America dominated the global protein detection quantification market and is expected to grow at the highest CAGR during the forecast period. The region is estimated to be driven by the US mainly due to the presence of leading market players in the country together with a well-established healthcare framework in the US. A combination of factors such as developed infrastructure, an increase in R&D investment, and growing cases of various diseases in the region are the factors attributed to the market growth in the U.S.

Asia Pacific is likely to come up as a rapidly growing region owing to rapid development of countries like India and China. Augmented investment for research and development activities together with rising cases of several diseases in the area is likely to boost the protein detection and quantification market in the region.

Continuous efforts of government and top-notch private firms in novel drug discovery and development are expected to impact proteomics growth in this country. For instance, recently researchers at The Scripps Research Institute (TSRI) have developed a new toolkit that enables them to discover and reveal the new functional characteristics of peptide biomolecules. They have developed new probes based on activity-based peptide -profiling (ABPP) for the detection of potential drug targets. This factor will drive the growth of the market in the region.

Competitive Analysis

The global protein detection quantification market is highly competitive with the presence of several international and local markets. Product diversification, revenue generation, and opportunities intensify the market competition Merck & Co., Inc., Danaher, RayBiotech, Inc., Inanovate, Shimadzu Corporation, PerkinElmer Inc, Bio-Rad Laboratories, Inc., Thermo Fisher Scientific, and GE Healthcare are the leading market players with significant market share. The major players are using product development, novel product launches, market expansion, and product diversification strategies for holding their position in the market.

The companies are entering into collaborations, mergers, strategic partnerships, and acquisitions to expand their presence and meet the rising demand for the protein detection quantification across the globe. For instance,

  • In April 2017, MilliporeSigma launched a new Single Molecule Counting Platform, termed SMCxPROTM, during the American Association for Cancer Research annual meet.
  • In August 2020, Oil-Dri Corporation of America, leading manufacturer of sorbent minerals, parent company to Amlan International, announces that the European Patent Office has issued Patent EP 2906238. The patent covers the unique formulation of two existing mineral-based natural feed additives, Varium for poultry and NeoPrime for swine that are helping global animal protein producers thrive in an era of antibiotic-free production.

Why Purchase the Report?

  • Visualize the composition of the global protein detection quantification market products in terms of technology, product, application and end-user and highlighting the critical commercial assets and players.
  • Identify commercial opportunities in the global protein detection quantification market by analyzing trends and co-development deals.
  • Excel data sheet with thousands of data points of global protein detection quantification market -level 4/5 segmentation.
  • PDF report with the most relevant analysis cogently put together after exhaustive qualitative interviews and in-depth market study.

*The global protein detection quantification market report will provide access to approximately 70 market data tables, 69 figures, and 250 pages.

Target Audience

  • Industry Investors/Investment Bankers
  • Suppliers/Buyers
  • Education & Research Institutes
  • Manufacturers
  • Research Professionals
  • Emerging Companies
  • Distributors

Table of Contents

1. Global Protein Detection Quantification Market Methodology and Scope

  • 1.1. Research Methodology
  • 1.2. Research Objective and Scope of the Report

2. Global Protein Detection Quantification Market - Market Definition and Overview

3. Global Protein Detection Quantification Market - Executive Summary

  • 3.1. Market Snippet by Technology
  • 3.2. Market Snippet by Product
  • 3.3. Market Snippet by Application
  • 3.4. Market Snippet by End-User
  • 3.5. Market Snippet by Region

4. Global Protein Detection Quantification Market Dynamics

  • 4.1. Market Impacting Factors
    • 4.1.1. Drivers
      • 4.1.1.1. Increasing need to comprehend various chronic diseases at a molecular level
      • 4.1.1.2. Rising demand for protein quantification in laboratories
    • 4.1.2. Restraints
      • 4.1.2.1. High cost of assays and technology are expected to limit the utilization
  • 4.2. Impact Analysis
  • 4.3. Opportunity

5. Global Protein Detection Quantification Market - Industry Analysis

  • 5.1. Porter's Five Forces Analysis
  • 5.2. Supply Chain Analysis
  • 5.3. Regulatory Analysis
  • 5.4. Pricing Analysis
  • 5.5. Product Analysis
  • 5.6. Post Sales Services Analysis

6. Global Protein Detection Quantification Market - By Technology

  • 6.1. Introduction
  • 6.2. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Technology
  • 6.3. Market Attractiveness Index, By Technology
    • 6.3.1. Colorimetric Assays *
      • 6.3.1.1. Introduction
      • 6.3.1.2. Market Size Analysis, US$ Mn, 2016-2025 and Y-o-Y Growth Analysis (%), 2019-2027
    • 6.3.2. Immunological methods
    • 6.3.3. Chromatography
    • 6.3.4. Mass Spectrometry
    • 6.3.5. Spectroscopy Instruments
    • 6.3.6. Others

7. Global Protein Detection Quantification Market - By Product

  • 7.1. Introduction
  • 7.2. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
  • 7.3. Market Attractiveness Index, By Product
    • 7.3.1. Kits & Reagents/Consumables
      • 7.3.1.1. Introduction
      • 7.3.1.2. Market Size Analysis, US$ Mn, 2016-2025 and Y-o-Y Growth Analysis (%), 2019-2027
    • 7.3.2. Instruments
    • 7.3.3. Services

8. Global Protein Detection Quantification Market - By Application

  • 8.1. Introduction
  • 8.2. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
  • 8.3. Market Attractiveness Index, By Application
    • 8.3.1. Drug discovery and development
      • 8.3.1.1. Introduction
      • 8.3.1.2. Market Size Analysis, US$ Mn, 2016-2025 and Y-o-Y Growth Analysis (%), 2019-2027
    • 8.3.2. Clinical Diagnosis
    • 8.3.3. Others

9. Global Protein Detection Quantification Market - By End-User

  • 9.1. Introduction
  • 9.2. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-User
  • 9.3. Market Attractiveness Index, By End-User
    • 9.3.1. Academic Research Institutes
      • 9.3.1.1. Introduction
      • 9.3.1.2. Market Size Analysis, US$ Mn, 2016-2025 and Y-o-Y Growth Analysis (%), 2019-2027
    • 9.3.2. Biotechnology and Pharmaceutical Companies
    • 9.3.3. Contract Research Organization
    • 9.3.4. Others

10. Global Protein Detection Quantification Market - By Region

  • 10.1. Introduction
  • 10.2. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Region
  • 10.3. Market Attractiveness Index, By Region
  • 10.4. North America
    • 10.4.1. Introduction
    • 10.4.2. Key Region-Specific Dynamics
    • 10.4.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Technology
    • 10.4.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
    • 10.4.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
    • 10.4.6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-User
    • 10.4.7. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
      • 10.4.7.1. U.S.
      • 10.4.7.2. Canada
      • 10.4.7.3. Mexico
  • 10.5. Europe
    • 10.5.1. Introduction
    • 10.5.2. Key Region-Specific Dynamics
    • 10.5.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Technology
    • 10.5.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
    • 10.5.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
    • 10.5.6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End-User
    • 10.5.7. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
      • 10.5.7.1. Germany
      • 10.5.7.2. U.K.
      • 10.5.7.3. France
      • 10.5.7.4. Rest of Europe
  • 10.6. South America
    • 10.6.1. Introduction
    • 10.6.2. Key Region-Specific Dynamics
    • 10.6.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Technology
    • 10.6.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
    • 10.6.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
    • 10.6.6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End User
    • 10.6.7. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
      • 10.6.7.1. Brazil
      • 10.6.7.2. Argentina
      • 10.6.7.3. Rest of South America
  • 10.7. Asia Pacific
    • 10.7.1. Introduction
    • 10.7.2. Key Region-Specific Dynamics
    • 10.7.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Technology
    • 10.7.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
    • 10.7.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
    • 10.7.6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End User
    • 10.7.7. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Country
      • 10.7.7.1. China
      • 10.7.7.2. India
      • 10.7.7.3. Japan
      • 10.7.7.4. Australia
      • 10.7.7.5. Rest of Asia Pacific
  • 10.8. Middle East and Africa
    • 10.8.1. Introduction
    • 10.8.2. Key Region-Specific Dynamics
    • 10.8.3. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Technology
    • 10.8.4. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Product
    • 10.8.5. Market Size Analysis, and Y-o-Y Growth Analysis (%), By Application
    • 10.8.6. Market Size Analysis, and Y-o-Y Growth Analysis (%), By End User

11. Global Protein Detection Quantification Market Competitive Landscape

  • 11.1. Competitive Scenario
  • 11.2. Market Positioning/Share Analysis
  • 11.3. Mergers and Acquisitions Analysis

12. Global Protein Detection Quantification Market Company Profiles

  • 12.1. Merck & Co., Inc. *
    • 12.1.1. Company Overview
    • 12.1.2. Product Portfolio and Description
    • 12.1.3. Key Developments
    • 12.1.4. Financial Overview
  • 12.2. Danaher
  • 12.3. RayBiotech, Inc.
  • 12.4. Inanovate, Inc.
  • 12.5. Shimadzu Corporation
  • 12.6. PerkinElmer Inc
  • 12.7. Bio-Rad Laboratories, Inc.
  • 12.8. Thermo Fisher Scientific
  • 12.9. GE Healthcare
  • 12.10. Hartalega Holdings Bhd
  • List is not exhaustive

13. Global Protein Detection Quantification Market - Premium Insights

14. Global Protein Detection Quantification Market - DataM

  • 14.1. Appendix
  • 14.2. About Us and Services
  • 14.3. Contact Us