Global Lactoferrin Market - 2021-2028
Lactoferrin is an iron-binding glycoprotein that is used in a variety of exocrine fluids, including breast milk. Lactoferrin can also be present in the eye, nose, respiratory tract, stomach, and other bodily fluids. It has various biological applications such as infection control, immunomodulation, gut flora enhancement, iron absorption, and a variety of other health-promoting properties. Also, its anti-inflammatory properties prevent the development of larger zits and cysts on skin, hence is being considered as an important ingredient in development of acne and skincare products. Moreover, lactoferrin is used as a drug to treat diarrhea, liver swelling (inflammation) caused by the hepatitis C virus (hepatitis C), low levels of healthy red blood cells (anemia) due to iron deficiency, the common cold, blood infection (sepsis), and a variety of other disorders, which is boosting the demand for lactoferrin in the pharmaceutical industry. Moreover, its usage in industrial agriculture to kill bacteria during meat processing, is further supporting the growth of the market. The global lactoferrin market valued USD XX million in 2020 and is estimated to reach USD XX million by 2028, growing at a CAGR of 11%
Skin diseases are one of the most common illnesses worldwide, and their prevalence is increasing. According to the American Academy of Dermatology Association, approximately 50 million Americans are affected by acne each year, with moderate acne affecting 85 percent of those aged 12 to 24. It is normally caused by an imbalance of the body's hormones. With acne being one of the most common skin conditions among teenagers, the demand for lactoferrin is widely growing in the development of acne products. According to a research published by National Library of Medicine, the usage of lactoferrin significantly decreases in inflammatory lesion count by 38.6% with total lesion count by 23.1%, and acne grade by 20.3% compared with the placebo group at 12 weeks. Hence, lactoferrin is widely used in wound healing and reduction in dermal immune responses by activating connective tissue with epidermal cells and regenerating the skin. According to the WHO, anemia affects over 1.62 billion people across the globe, with the highest prevalence observed among pre-school age children, accounting 47.4% of the total affected population. Lactoferrin is a new age solution for anemia and is widely recognized to be part of the transferrin family which regulates the levels of free iron in body fluid along with increasing the levels of hemoglobin by enhancing the ability to bind iron.
Even though, lactoferrin has a number of health benefit, its over consumption can still result in lot many side effects and be a hindrance to the growth of the market. Diarrhea, rash, lack of appetite, nausea, chills, and constipation are all symptoms of too much lactoferrin. Lactoferrin doses of up to 250 mg per day are said to be healthy for pregnant women.
Lactoferrin is being extensively used in infant formula. Lactoferrin is only of the two important proteins that are found in breast milk. Lactoferrin's antibacterial, anti-inflammatory and immunomodulator properties, nervous system development and has been studied to have significant impact on the growth of infants. Several studies have shown that lactoferrin especially bovine plays an important role in gut flora and boost resistance to infections. Bovine lactoferrin regulates gut flora by increasing Bifidobacterium concentration levels and reducing clostridium concentration levels in infants. For underweight new-borns, lactoferrin has especially shown positive impact, as reduce the risk of delayed-onset septicaemia (bacterial or fungal). All these factors are contributing to the increased demand for lactoferrin in infant formulas. The use of lactoferrin in infant formula is keeping up the growth of lactoferrin market, as baby food manufacturers are trying to provide infants with similar nutritional content that are found in breast milk. In September 2020, Friesland Campina announced that it is increasing its lactoferrin production capacity in the Netherlands in response to increasing demand for infant nutrition, particularly premium infant formula products.
Cosmetics segment is anticipated to witness the strongest gains during the forecast period, owing to the emollient nature and inherent properties of lactoferrin that help reduce skin inflammation. It does this by inhibiting the production of cytokine mediators which causes inflammation. Most prolific advantage of lactoferrin includes its potential usage as non-toxic and anti-cancer agent.
Asia-Pacific is the largest shareholder of the global lactoferrin market with the majority of babies getting supplemented with infant formula belonging to the Asia-Pacific. India, China, and Japan were found to be the biggest regional markets for the product. This significant share of Asia pacific can be attributed to the rising spending capacity of the consumers. The presence of a large consumer base in these countries along with increasing birth rates among the population is anticipated to create growth opportunities. Asia Pacific, unlike most other regions, has a sizable number of medium and small businesses. Moreover, with increasing literacy rate coupled with rising consumer awareness regarding infant nutrition, personal care, and pharmaceutical products along with consumer inclination toward organic products is expected to drive the growth. China accounts for the majority of the shares of the market, due to the lowest breastfeeding rates in country. The abandonment of one child policy has especially contributed to the rising demand in the infant formula.
North America sized to be the second largest market for lactoferrin in 2020 with a revenue share of XX% in 2020. U.S. emerged to be the largest market. Growing incidence of digestive distresses has driven product demand across the country. Furthermore, rise in the numbers of specialty stores, hypermarkets, supermarkets, and incentivized marketing systems adopted by brand owners to expand its sales is projected to bolster the regional product demand in the forthcoming years.
The market is highly fragmented in nature and is characterized by numerous small and medium sized companies. This is mainly due to the nature of logistical indifference created by dairy producers in different countries. Dairy products are short lived-in nature and need to reach the production plant on time, this creates a disparity among the producers and small and medium sized entities taking the advantage by sourcing local dairy on time to meet production schedule. Most companies are directly involved in retailing through online shopping platforms, hypermarkets, supermarkets, specialty stores, and local convenience stores. In March 2020, Conagen, Inc. announced the discovery and development of a patented lactoferrin protein that resembles the nutritional properties of lactoferrin contained in breast milk. At commercial scale, the first-of-its-kind natural lactoferrin protein is manufactured through a fermentation process. In June 2020, Australian Health & Wellness company JatCorp Ltd. launched lactoferrin enriched camel milk powder under the Auveno brand. At the end of 2020, Moringa Milk Industry announced its subsidiary at Milei GmbH will more than double its lactoferrin production capacity by 2021 as demand for lactoferrin has grown. The firm aims to increase production of its lactoferrin-related products to approximately 170 tons, more than doubt the amount in 2019.
Certain market segments have experienced a growth in product demand due to its higher efficiency in improving immunity. According to a research article published by iMedPub, lactoferrin has anti-inflammatory and immunomodulatory properties against COVID-19 and its use as nutritional supplements has been proposed by various health professionals. This is anticipated to boost its consumption in countries like China, Japan, and U.S during the pandemic. One recent in-vitro study even suggested that the ingredient may provide a protective effect against Covid-19. Also, the increasing demand, is exerting a pressure on the suppliers and manufacturers. Thus, some of the market players have responded to the rising demand through capacity expansions. For instance, Bega Cheese Ltd. announced the completion of the expansion of its koroit Australia plant, at a cost of USD 34 million in 2019. The expansion has doubled the lactoferrin production capacity of Bega Cheese