表紙
市場調查報告書

促使處方藥(Rx)轉換為非處方藥(非醫療)的因素

Drivers of Non-medical Rx Switching

出版商 FirstWord 商品編碼 940405
出版日期 內容資訊 英文
商品交期: 最快1-2個工作天內
價格
促使處方藥(Rx)轉換為非處方藥(非醫療)的因素 Drivers of Non-medical Rx Switching
出版日期: 2020年04月21日內容資訊: 英文
簡介

保險公司極有動力實現生物仿製藥的成本節約,但是他們採取什麼策略來保證和鼓勵醫生和患者?財政影響模型,目標,現實世界證據(RWE),指南以及醫院與保險公司之間的共享儲蓄都起著作用。生物仿製藥的轉移在世界範圍內是多種多樣的,這提供了一個向轉移程度高的市場學習的機會,並將這些經驗教訓應用於轉移程度低的市場。

本報告調查了推動從處方藥(Rx)轉換為非處方藥(非醫療)轉換/轉換/轉換的因素,並節省了成本或提高了生物仿製藥轉換的成本效率其中包括鼓勵轉移的目標,經濟激勵措施,招標,RWE(現實世界的證據),國家指南的重要性,患者偏好的重要性,製造商在鼓勵向利益相關者轉移方面的作用等。

內容

要點

調查方法和目的

主要注意事項摘要

問題和注意事項

  • 非醫療轉移的定義(將處方藥轉移/轉換為非處方藥)
    • 問題概述
    • 問題
    • 重要考慮
    • 報價
    • 來源
  • 國際轉移利益
  • 支持轉移的經濟證據
  • 轉移成本
  • 轉移目標設定
  • 出價可能導致轉移
  • 指南可能會導致轉移
  • 美國保險公司的變化導致轉移可用
  • 鼓勵轉移的財政激勵措施
  • 藥房級別的轉移
  • 處方者的態度和轉換
  • 轉移和耐心
  • 真實世界證據(RWE)在促進轉移中作用的變化
  • 製造商對生物仿製藥的教育作用
  • 患者群體在生物仿製藥教育中的作用
  • 轉移為創新提供資金空間
目錄
Product Code: 596201544

The strategies that are promoting wider use of biosimilars

Payers are highly motivated to realise the cost savings of biosimilars, but what strategies are they using to reassure and encourage physicians and patients? Budget impact models, establishing targets, real world evidence, guidelines and sharing savings between hospitals and payers all play a role. Biosimilar developers need to understand the trends and identify where they can positively engage.

Biosimilar switching is variable across the globe and this offers the opportunity to learn from those markets where switching is high and apply those lessons in markets where switching is low. That is why, in ‘Drivers of Non-medical Rx Switching’, we interviewed payer and industry experts who reveal the techniques and strategies that are being used to propel wider biosimilar adoption and use.

Experts explore key questions such as...

  • Is the pursuit of savings or cost effectiveness driving biosimilar switching?
  • Are the predicted savings from biosimilar switching being seen in real life?
  • How important are targets, financial incentives, tendering, RWE and national guidelines for encouraging switching?
  • How can prescriber attitudes act as a brake on biosimilar switching?
  • How important are patient preferences?
  • What practical role is there for manufacturers in encouraging stakeholders to switch?

What experts say...

"When it's biologics to biosimilars, it's clearly driven by cost. It's the biggest argument used by payers who are pushing for switching. Even biosimilar companies, when they launch their biosimilars, they do the health economic studies to show that with a biosimilar they can save a great amount for the healthcare system. So cost, definitely, is the biggest driver." Global Portfolio Manager , Germany.

"We were able to do those budget impact models like that and see significant savings. But now as you start seeing the agents that are used more in the outpatient setting, it's very difficult to do those analyses because you do see the cost savings when you just look at the cost and model that out, but it's offset by what your reimbursement and what your payer mix is. If your payer mix is primarily the state - so Medicare, Medicaid - then you might be okay switching to the biosimilar because that would be the preferred product, and the government has incentivised the use of those products and so you get additional reimbursement. But if your primary payer mix is private insurance, they may or may not have negotiated an additional rebate contract with the originator, and even though you do those cost analyses and assume that you'd be saving a significant amount of money by switching to the biosimilar, if you look at the reimbursement side, you're actually losing." Manager of Medication Policy and Formulary Management , US.

"Gain share agreements work particularly well. A proportion of the savings go back into the hospital. So, you might go for a 50:50 gain share between CCGs and hospitals - so 50 percent of the savings back to the hospital, 50 percent to the CCG. I know of one hospital where they were discussing over a three-year period where they would get 70 percent of the savings in the first year, then get 40 percent in the second, and then 10 percent in the third. The hospital will want to maximise its savings as quickly as possible and so will move patients over as quickly as possible." Biosimilar Account Manager , UK.

What to expect

A detailed expert report exploring the drivers of biosimilar switching and the financial, physician and patient issues that biosimilar developers need to understand and engage with:

  • An examination of 15 key issues that influence switching to biosimilars
  • 17 targeted questions to US and European payer and industry experts
  • Their responses which provided 55 insights supported by 125 directly quoted comments

Expert contributors

The experts selected for this report all had relevant experience, including:

  • Working in a company/industry association actively involved in current switching and monitoring switching to biosimilars
  • Working at a payer or within a healthcare provider actively involved in current switching and monitoring future drug switching/biosimilars
  • Having published papers on switching
  • Knowledge of current trends in switching and biosimilars

To ensure candid views were expressed we have agreed to keep their identities anonymous.

The experts who contributed

  • A professor of rheumatology affiliated to a University Hospital in France, with direct experience of prescribing biosimilars and switching from originator biologics
  • A biologics pharmacist, working at a National Health Service (NHS) hospital in the UK, with responsibility for switching from biologics to biosimilars in the hospital and has published on exploring switching in practice
  • Biosimilars account manager with responsibilities for biosimilars at a top 10 global pharmaceutical company in the UK
  • Former business unit director at a top 10 pharmaceutical company with responsibility for planning a biosimilar launch in the UK
  • Pharmacist and manager of Medication Policy and Formulary Management at a non-profit healthcare system in the USA, with responsibilities for assessing the impact of switching from biologic to biosimilar
  • A Director for Biosimilars Access, Reimbursement and Health Economics at a top 10 global pharmaceutical company, with global responsibilities
  • A product manager at a drug manufacturer with a portfolio of biosimilars, based in Spain
  • A global portfolio manager at a pharmaceutical company with a portfolio of biosimilars, based in Germany

Why Choose FirstWord ExpertViews?

FirstWord's ExpertViews reports reveal the real world insights of knowledgeable experts to analyse in detail key commercial and market trends that pharma management need to understand if they are to effectively respond to critical developments. These highly-focussed reports:

  • Are based on primary research with experts whose knowledge and current experience is proven
  • Present clear insights and actionable intelligence
  • Include only the latest primary research and findings-we don't recycle content or pad out reports with secondary source material

Table of Contents

Subject synopsis

Research methodology and objectives

Key insights summary

Issues and insights

  • Defining non-medical switching
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources
  • International interest in switching
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Intelligence exhibits
    • Sources
  • Economic evidence to support switching
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources
  • Costs can be generated by switching
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources
  • Setting targets for switching
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources
  • Tendering can lead to switching
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources
  • Guidelines can lead to switching
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources
  • Changing insurer in the US can lead to switching
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources
  • Financial incentives to encourage switching
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources
  • Switching at pharmacy level
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources
  • Prescriber attitudes and switching
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources
  • Switching and patients
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources
  • Changing role for real-world evidence to drive switching
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources
  • A role for manufacturers to educate on biosimilars
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources
  • A role for patient groups to educate on biosimilars
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources
  • Switching provides headroom to fund innovation
    • Issue summary
    • Questions
    • Key insights
    • Supporting quotes
    • Sources