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急性呼吸窘迫症候群(ARDS)- 流行病學預測 2028年

Acute Respiratory Distress Syndrome (ARDS) - Epidemiology Forecast-2028

出版商 DelveInsight Business Research LLP 商品編碼 524420
出版日期 內容資訊 英文 60 Pages
商品交期: 最快1-2個工作天內
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急性呼吸窘迫症候群(ARDS)- 流行病學預測 2028年 Acute Respiratory Distress Syndrome (ARDS) - Epidemiology Forecast-2028
出版日期: 2019年09月01日內容資訊: 英文 60 Pages
簡介

主要7個國家(美國、英國、德國、法國、西班牙、義大利、日本)的急性呼吸窘迫症候群(ARDS)的罹患數2017年估算為81萬5,490人。

本報告提供主要7個國家(美國、英國、德國、法國、西班牙、義大利、日本)的急性呼吸窘迫症候群(ARDS)的流行病學的相關調查,疾病概要,重病度、危險因素、各國罹患數的變化與預測詳細彙整。

目錄

第1章 重要洞察

第2章 急性呼吸窘迫症候群(ARDS):流行病學概要

  • 分佈情形(成果值)
  • 分佈情形(預測值)

第3章 急性呼吸窘迫症候群(ARDS):疾病的背景和概要

  • 簡介
  • 原因和風險因素
  • 病理生理學
  • 分期
  • 人工呼吸器相關肺傷害(VILI)
  • 人工呼吸器相關肺傷害(VILI)的決策因素
  • 急性呼吸窘迫症候群(ARDS)的診斷

第4章 流行病學和患者人口

  • 主要調查結果
  • 調查手法

第5章 主要7個國家的急性呼吸窘迫症候群(ARDS)的流行病學分析

  • 主要7個國家的急性呼吸窘迫症候群(ARDS)總罹患數
  • 主要7個國家的急性呼吸窘迫症候群(ARDS)罹患數:各重症度

第6章 美國的流行病學

  • 假設和根據
  • 急性呼吸窘迫症候群(ARDS)的總罹患數
  • 急性呼吸窘迫症候群(ARDS)的罹患數:各重症度
  • 急性呼吸窘迫症候群(ARDS)的罹患數:各危險因素

第7章 歐洲5個國家的流行病學

  • 德國的流行病學
    • 假設和根據
    • 急性呼吸窘迫症候群(ARDS)的總罹患數
    • 急性呼吸窘迫症候群(ARDS)的罹患數:各重症度
    • 急性呼吸窘迫症候群(ARDS)的罹患數:各危險因素
  • 法國的流行病學
    • 假設和根據
    • 急性呼吸窘迫症候群(ARDS)的總罹患數
    • 急性呼吸窘迫症候群(ARDS)的罹患數:各重症度
    • 急性呼吸窘迫症候群(ARDS)的罹患數:各危險因素
  • 義大利的流行病學
    • 假設和根據
    • 急性呼吸窘迫症候群(ARDS)的總罹患數
    • 急性呼吸窘迫症候群(ARDS)的罹患數:各重症度
    • 急性呼吸窘迫症候群(ARDS)的罹患數:各危險因素
  • 西班牙的流行病學
    • 假設和根據
    • 急性呼吸窘迫症候群(ARDS)的總罹患數
    • 急性呼吸窘迫症候群(ARDS)的罹患數:各重症度
    • 急性呼吸窘迫症候群(ARDS)的罹患數:各危險因素
  • 英國的流行病學
    • 假設和根據
    • 急性呼吸窘迫症候群(ARDS)的總罹患數
    • 急性呼吸窘迫症候群(ARDS)的罹患數:各重症度
    • 急性呼吸窘迫症候群(ARDS)的罹患數:各危險因素

第8章 日本的流行病學

  • 假設和根據
  • 急性呼吸窘迫症候群(ARDS)的總罹患數
  • 急性呼吸窘迫症候群(ARDS)的罹患數:各重症度
  • 急性呼吸窘迫症候群(ARDS)的罹患數:各危險因素

第9章 附錄

  • 報告方法

第10章 DelveInsight的服務內容

第11章 免責聲明

第12章 關於DelveInsight

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目錄
Product Code: DIEI0002

DelveInsight's 'Acute Respiratory Distress Syndrome (ARDS)-Epidemiology Forecast-2028 report delivers an in-depth understanding of the disease, historical, and forecasted epidemiology of ARDS in the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.

Geography Covered

  • The United States
  • EU5 (Germany, France, Italy, Spain, and the United Kingdom)
  • Japan

Study Period: 2017-2028

Acute Respiratory Distress Syndrome (ARDS)-Disease Understanding

Acute lung injury (ALI) is a common condition characterized by acute severe hypoxia that is not due to left atrial hypertension. The term ALI encompasses a continuum of clinical and radiographic changes that affect the lungs with acute respiratory distress syndrome (ARDS) representing the more severe end of this continuum. Despite advances in the understanding of the pathophysiology and management of ALI, it is still associated with high mortality. It is not known by the researchers regarding who will develop ARDS. Several factors, such as obesity, low protein in the blood, consumption of alcohol, blood transfusion. Several physiological factors, such as blood acidemia, hypoalbuminemia, low respiratory compliance, and high lactate also increase the risk of developing ARDS.

ARDS is characterized by an acute, diffuse, inflammatory lung injury, leading to increased alveolar-capillary permeability, increased lung weight, and loss of aerated lung tissue. Clinically, this establishes as hypoxemia, with bilateral opacities on chest radiography, associated with reduced lung compliance and increased venous admixture and physiological dead space. Morphologically, diffuse alveolar damage is observed in the acute phase of ARDS.

The DelveInsight's ARDS Epidemiology report gives a thorough understanding of the ARDS by including details, such as disease definition, classification, symptoms, etiology, pathophysiology, diagnostic trends.

Acute Respiratory Distress Syndrome (ARDS)-Epidemiology

The ARDS epidemiology division provides insights about historical and current patient pool and forecasted trends for every seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders (KOL). This part of the DelveInsight's report also provides the diagnosed patient pool and their trends along with assumptions undertaken.

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology [segmented by Total Incident Population of Acute Respiratory Distress Syndrome in the 7MM, Severity Specific Incident Population of Acute Respiratory Distress Syndrome in the 7MM and Incident Population of ARDS by Risk Factors in the 7MM] scenario of ARDS in the 7MM covering United States, EU5 countries (Germany, France, Italy, Spain, and United Kingdom) and Japan from 2017 to 2028.

As per DelveInsight's analysis, the total Incident Population of Acute Respiratory Distress Syndrome (ARDS) in the 7MM was found to be 815,490 in 2017 and expected to increase during the forecast period of 2017-2028. The estimates show the incidence was higher in the United States and among the European 5 countries, Germany had the highest incident population of ARDS followed by Italy.

On the other hand, Spain had the lowest incident population of ARDS. Another estimate of Delveinsight's analysis shows that in terms of severity-specific incidence, a similar trend is observed in all countries, with the majority of the cases witnessed for moderate ARDS, except France, where severe cases of ARDS accounted for maximum patient population. Furthermore, the highest number of incident cases were assessed for ARDS due to Pneumonia, in all the 7MM countries, except the United Kingdom, in which Sepsis was the primary risk factor for ARDS.

Report Scope

  • The report covers a detailed overview of ARDS explaining its causes, symptoms, classification, pathophysiology, diagnosis and treatment patterns
  • The report provides insight about the historical and forecasted patient pool for seven major markets covering the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom) and Japan
  • The report assesses the disease risk and burden and highlights the unmet needs of ARDS
  • The report helps to recognize the growth opportunities in the 7MM with respect to the patient population
  • The report provides the segmentation of the disease epidemiology by type-specific cases and severity specific cases of ARDS in the 7MM

Acute Respiratory Distress Syndrome (ARDS) Report Key Strengths

  • 10-Year Forecast of ARDS epidemiology
  • 7MM Coverage
  • Total Incident Population of Acute Respiratory Distress Syndrome in the 7MM
  • Severity Specific Incident Population of Acute Respiratory Distress Syndrome in the 7MM
  • Incident Population of Acute Respiratory Distress Syndrome by Risk Factors in the 7 MM

Acute Respiratory Distress Syndrome (ARDS) Report Assessment

  • Patient Segmentation
  • Disease Risk and Burden
  • Risk of disease by the segmentation
  • Factors driving growth in a specific patient population

Table of Contents

1. Key Insights

2. Acute Respiratory Distress Syndrome (ARDS): Epidemiology Overview at a Glance

  • 2.1. Total Epidemiology Distribution of ARDS in 2017
  • 2.2. Total Epidemiology Distribution of ARDS in 2028

3. Acute Respiratory Distress Syndrome (ARDS): Disease Background and Overview

  • 3.1. Introduction
    • 3.1.1. Consensus Definitions of Acute Lung Injury and Acute Respiratory Distress Syndrome (ARDS)
    • 3.1.2. Development of Berlin Definition of ARDS
    • 3.1.3. Problems with the AECC definition and subsequent Berlin definition of acute respiratory distress syndrome (ARDS)
  • 3.2. Causes and Risk Factors
    • 3.2.1. Risk Factors of Acute Respiratory Distress Syndrome (ARDS)
  • 3.3. Pathophysiology of Acute Respiratory Distress Syndrome (ARDS)
    • 3.3.1. Inflammatory Processes in ARDS
    • 3.3.2. The initial event of injury
    • 3.3.3. Endothelial Damage
    • 3.3.4. Specific Mediators of Inflammation and Lung Damage in ARDS
    • 3.3.5. Altered Pulmonary Physiology in ARDS
    • 3.3.6. Genetics
  • 3.4. Stages of Acute Respiratory Distress Syndrome (ARDS)
  • 3.5. Ventilator-Induced Lung Injury (VILI)
  • 3.6. Major Determinants of VILI
    • 3.6.1. Ventilator determinants of VILI
    • 3.6.2. Patient determinants of VILI
  • 3.7. Diagnosis of Acute Respiratory Distress Syndrome (ARDS)
    • 3.7.1. Imaging techniques in ARDS
    • 3.7.2. Imaging findings in ARDS
    • 3.7.3. Differential Diagnosis

4. Epidemiology and Patient Population

  • 4.1. Key Findings
  • 4.2. Methodology

5. 7MM Epidemiology Analysis

  • 5.1. Total Incident Population of Acute Respiratory Distress Syndrome (ARDS) in the 7MM
  • 5.2. Severity Specific Incident Population of Acute Respiratory Distress Syndrome (ARDS) in the 7MM

6. United States Epidemiology

  • 6.1. Assumptions and Rationale
  • 6.2. Total Incident Population of Acute Respiratory Distress Syndrome (ARDS) in the United States
  • 6.3. Severity-Specific Incident Population of ARDS in the United States
  • 6.4. Incident Population of ARDS by Risk Factors in the United States

7. EU5 Epidemiology

  • 7.1. Germany Epidemiology
    • 7.1.1. Assumptions and Rationale
    • 7.1.2. Total Incident Population of Acute Respiratory Distress Syndrome (ARDS) in Germany
    • 7.1.3. Severity-Specific Incidence of ARDS in Germany
    • 7.1.4. Incident Population of ARDS by Risk Factors in Germany
  • 7.2. France Epidemiology
    • 7.2.1. Assumptions and Rationale
    • 7.2.2. Total Incident Population of Acute Respiratory Distress Syndrome (ARDS), in France
    • 7.2.3. Severity-Specific Incidence of ARDS in France
    • 7.2.4. Incident Population of ARDS by Risk Factors in France
  • 7.3. Italy Epidemiology
    • 7.3.1. Assumptions and Rationale
    • 7.3.2. Total Incident Population of Acute Respiratory Distress Syndrome (ARDS) in Italy
    • 7.3.3. Severity-Specific Incidence of ARDS in Italy
    • 7.3.4. Incident Population of ARDS by Risk Factors in Italy
  • 7.4. Spain Epidemiology
    • 7.4.1. Assumptions and Rationale
    • 7.4.2. Total Incident Population of Acute Respiratory Distress Syndrome (ARDS) in Spain
    • 7.4.3. Severity-Specific Incidence of ARDS in Spain
    • 7.4.4. Incident Population of ARDS by Risk Factors in Spain
  • 7.5. United Kingdom Epidemiology
    • 7.5.1. Assumptions and Rationale
    • 7.5.2. Total Incident Population of Acute Respiratory Distress Syndrome (ARDS) in the United Kingdom
    • 7.5.3. Severity-Specific Incidence of ARDS in the United Kingdom
    • 7.5.4. Incident Population of ARDS by Risk Factors in the United Kingdom

8. Japan Epidemiology

  • 8.1. Assumptions and Rationale
  • 8.2. Total Incident Population of Acute Respiratory Distress Syndrome (ARDS), ARDS in Japan
  • 8.3. Severity-Specific Incidence of ARDS in Japan
  • 8.4. Incident Population of ARDS by Risk Factors in Japan

9. Appendix

  • 9.1. Report Methodology

10. DelveInsight Capabilities

11. Disclaimer

12. About DelveInsight

List of Tables

  • Table 1 Definition of Acute Respiratory Distress Syndrome (ARDS)
  • Table 2 American European Consensus Conference Criteria for Acute Lung Injury (ALI) and the Acute Respiratory Distress Syndrome (ARDS)
  • Table 3 Berlin Definition of Mild, Moderate, and Severe Acute Respiratory Distress Syndrome (ARDS)
  • Table 4 Factors That Distinguish ARDS, CHF, and Pneumonia
  • Table 5 Total Incident Population of ARDS in the 7MM (2017-2028)
  • Table 6 Severity-Specific Incident Population of ARDS in the 7MM (2017-2028)
  • Table 7 Total Incident Population of ARDS in the US (2017-2028)
  • Table 8 Severity-Specific Incidence of ARDS in the US (2017-2028)
  • Table 9 Incidence of ARDS by Risk Factors in the US (2017-2028)
  • Table 10 Total Incident Population of ARDS in Germany (2017-2028)
  • Table 11 Severity-Specific Incidence of ARDS in Germany (2017-2028)
  • Table 12 Incident Population of ARDS by Risk Factors in Germany (2017-2028)
  • Table 13 Total Incident Population of ARDS in France (2017-2028)
  • Table 14 Severity-Specific Incidence of ARDS in France (2017-2028)
  • Table 15 Incident Population of ARDS by Risk Factors in France (2017-2028)
  • Table 16 Total Incident Population of ARDS in Italy (2017-2028)
  • Table 17 Severity-Specific Incidence of ARDS in Italy (2017-2028)
  • Table 18 Incident Population of ARDS by Risk Factors in Italy (2017-2028)
  • Table 19 Total Incident Population of ARDS in Spain (2017-2028)
  • Table 20 Severity-Specific Incidence of ARDS in Spain (2017-2028)
  • Table 21 Incident Population of ARDS by Risk Factors in Spain (2017-2028)
  • Table 22 Total Incident Population of ARDS in the UK (2017-2028)
  • Table 23 Severity-Specific Incidence of ARDS in the UK (2017-2028)
  • Table 24 Incident Population of ARDS by Risk Factors in the UK (2017-2028)
  • Table 25 Total Incident Population of ARDS in Japan (2017-2028)
  • Table 26 Severity-Specific Incidence of ARDS in Japan (2017-2028)
  • Table 27 Incident Population of ARDS by Risk Factors in Japan (2017-2028)

List of Figures

  • Figure 1 Risk factors of Acute Respiratory Distress Syndrome (ARDS)
  • Figure 2 A simplified model of the pathogenesis of ARDS
  • Figure 3 Effects of Mast Cell Activation
  • Figure 4 Total Incident Population of ARDS in the 7MM (2017-2028)
  • Figure 5 Severity-Specific Incident Population of ARDS in the 7MM (2017-2028)
  • Figure 6 Total Incident Population of ARDS in the US (2017-2028)
  • Figure 7 Severity-Specific Incidence of ARDS in the US (2017-2028)
  • Figure 8 Incidence of ARDS by Risk Factors in the US (2017-2028)
  • Figure 9 Total Incident Population of ARDS in Germany (2017-2028)
  • Figure 10 Severity-Specific Incidence of ARDS in Germany (2017-2028)
  • Figure 11 Incident Population of ARDS by Risk Factors in Germany (2017-2028)
  • Figure 12 Total Incident Population of ARDS in France (2017-2028)
  • Figure 13 Severity-Specific Incidence of ARDS in France (2017-2028)
  • Figure 14 Incident Population of ARDS by Risk Factors in France (2017-2028)
  • Figure 15 Total Incident Population of ARDS in Italy (2017-2028)
  • Figure 16 Severity-Specific Incidence of ARDS in Italy (2017-2028)
  • Figure 17 Age-Specific Incidence of ARDS in Italy (2017-2028)
  • Figure 18 Total Incident Population of ARDS in Spain (2017-2028)
  • Figure 19 Severity-Specific Incidence of ARDS in Spain (2017-2028)
  • Figure 20 Incident Population of ARDS by Risk Factors in Spain (2017-2028)
  • Figure 21 Total Incident Population of ARDS in the UK (2017-2028)
  • Figure 22 Severity-Specific Incidence of ARDS in the UK (2017-2028)
  • Figure 23 Incident Population of ARDS by Risk Factors in the UK (2017-2028)
  • Figure 24 Total Incident Population of ARDS in Japan (2017-2028)
  • Figure 25 Severity-Specific Incidence of ARDS in Japan (2017-2028)
  • Figure 26 Incident Population of ARDS by Risk Factors in Japan (2017-2028)