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腦膜炎疫苗:Nimenrix

Nimenrix

出版商 Datamonitor Healthcare 商品編碼 912153
出版日期 內容資訊 英文 13 Pages
商品交期: 最快1-2個工作天內
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腦膜炎疫苗:Nimenrix Nimenrix
出版日期: 2019年09月03日內容資訊: 英文 13 Pages
簡介

本報告涵括Nimenrix (腦膜炎A,C,W135及Y群結合疫苗) ,提供醫藥品概要,產品簡介等。

概要

  • 醫藥品概要
  • 產品簡介
  • Nimenrix:腦膜炎疫苗
目錄
Product Code: DMKC0182438

Drug Overview

Nimenrix (quadrivalent polysaccharide tetanus toxoid conjugate vaccine; Pfizer) is a conjugated polysaccharide vaccine indicated for active immunization to prevent invasive meningococcal disease (IMD) caused by Neisseria meningitidis (N. meningitidis) serogroups A, C, Y, and W-135 in individuals from the age of six weeks. It induces the production of bactericidal antibodies against capsular polysaccharides of N. meningitidis group A, C, W-135, and Y.

Nimenrix is the only meningococcal vaccine against serotypes A, C, W-135, and Y (MenACWY) recommended for use in infants as early as six weeks of age in the EU. Despite that, it will continue to face significant competition in the European market from Menveo (quadrivalent oligosaccharide diphtheria CRM-197 conjugate vaccine; GlaxoSmithKline), which was approved two years before Nimenrix. As national recommendations restrict the use of MenACWY vaccines to at-risk, usually adult populations, the commercial potential of Nimenrix is limited. Sales of Nimenrix will be further threatened by pipeline vaccine MenABCW-135Y (pentavalent meningococcal conjugate vaccine; GlaxoSmithKline) starting from 2022, if it manages to demonstrate non-inferior immunogenicity against all five strains when compared to marketed vaccines.

TABLE OF CONTENTS

OVERVIEW

  • Drug Overview
  • Product Profiles
  • Nimenrix : Meningococcal vaccines

LIST OF TABLES

  • Table 1: Nimenrix drug profile
  • Table 2: Approval history of Nimenrix for meningococcal vaccination in the five major EU markets
  • Table 3: Late-phase trials of Nimenrix for meningococcal vaccination
  • Table 4: Nimenrix for meningococcal disease - SWOT analysis
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