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市場調查報告書

蛋白質表現的全球市場

Protein Expression: Global Markets

出版商 BCC Research 商品編碼 785745
出版日期 內容資訊 英文 154 Pages
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蛋白質表現的全球市場 Protein Expression: Global Markets
出版日期: 2019年02月05日內容資訊: 英文 154 Pages
簡介

全球蛋白質表現市場,預測將從2017年的18億成長到2022年31億美元,並以11.3%的年複合成長率 (CAGR) 成長。

本報告提供全球蛋白質表現市場相關調查,市場定義和概要,各市場區隔、各地區的市場分析與預測,競爭情形分析,及主要企業簡介等資訊。

第1章 簡介

第2章 摘要、亮點

第3章 市場、技術背景

  • 市場定義
  • 蛋白質表現市場概要
  • 蛋白質表現系統的簡介
  • 蛋白質合成設備
  • 蛋白質表現是什麼?
  • 蛋白質製作方法
  • 基因複製技術
  • 重組蛋白質表現系統一般使用的組成型啟動子及誘導型啟動子
  • 重組蛋白質的製造
  • 表現系統比較
  • 蛋白質的製造相關問題
  • 現在實施中的蛋白質表現臨床實驗
  • 市場動態

第4章 全球蛋白質表現系統市場:各類型

  • 簡介
  • 原核細胞表現系統
  • 哺乳類細胞表現系統
  • 昆蟲細胞表現系統
  • 酵母菌表現系統
  • 無細胞表現系統
  • 藻基表現系統

第5章 全球蛋白質表現系統市場:各產品、服務

  • 概要
  • 試劑
  • 表現媒介
  • 勝任細胞
  • 設備

第6章 全球蛋白質表現系統市場:各用途

  • 簡介
  • 治療
  • 產業
  • 研究

第7章 全球蛋白質表現系統市場:各終端用戶

  • 概要
  • 醫藥品、生物科技企業
  • 大學研究機關
  • CRO
  • 其他

第8章 全球蛋白質表現系統市場:各地區

  • 北美
  • 歐洲
  • 亞太地區
  • 其他 (ROW)

第9章 政府法規

  • 一般製造指南
  • 出發原料的管理
  • 製造工程的管理
  • 原料藥、醫藥品的管理

第10章 專利檢討

  • 專利分析
  • 組織的專利、專利申請

第11章 競爭情形

第12章 企業簡介

  • ABNOVA (TAIWAN) CORP.
  • ACCELAGEN INC.
  • AGILENT TECHNOLOGIES INC.
  • BIOMATIK
  • BIO-RAD LABORATORIES INC.
  • DOMAINEX LTD.
  • ENZO LIFE SCIENCES INC.
  • EXON BIOSYSTEMS
  • GENSCRIPT
  • LONZA GROUP AG
  • LUCIGEN CORP.
  • MERCK KGAA
  • NEW ENGLAND BIOLABS INC.
  • NOVOPROTEIN SCIENTIFIC INC.
  • ORIGENE TECHNOLOGIES INC.
  • OXFORD EXPRESSION TECHNOLOGIES LTD.
  • PROMEGA CORP.
  • PROTEOGENIX INC.
  • QIAGEN INC.
  • R&D SYSTEMS INC.
  • SINO BIOLOGICAL INC.
  • SYNGENE
  • SYNTHETIC GENOMICS INC.
  • TAKARA HOLDINGS INC.
  • THERMO FISHER SCIENTIFIC INC.

第13章 附錄

目錄
Product Code: BIO165A

Report Highlights:

The global market for protein expression should grow from $1.8 billion in 2017 to $3.1 billion by 2022 at a compound annual growth rate (CAGR) of 11.3% from 2017 through 2022.

North American market for protein expression should grow from $693 million in 2017 to $1.2 billion by 2022 at a CAGR of 10.8% from 2017 through 2022.

Asia-Pacific market for protein expression should grow from $389 million in 2017 to $687 million by 2022 at a CAGR of 12.0% from 2017 through 2022.

Report Scope:

This research report presents an in-depth analysis of the global market for protein expression by system type, products and services, applications, end users and regional markets. The report includes key protein expression systems that are incorporated in several therapeutic treatment methods. It discusses the role of supply chain members from manufacturers to researchers. The report provides an in-depth analysis of key companies operating in the global market for protein expression. A patent analysis focuses on describing technological trends across periods of time and regions, such as the U.S., Europe and Japan.

The protein expression market is mainly segmented into the following system types: prokaryotic expression systems, mammalian cell expression systems, insect cell expression systems, yeast expression systems, cell-free expression systems and algal-based expression systems. This market is further segmented based on products and services into reagents, expression vectors, competent cells, instruments and services. The market study details end users and applications, and ongoing activity in the research and development area. The market is segmented by region into North America, Europe, Asia-Pacific and the rest of the world (ROW). Companies profiled in this report include Thermo Fisher Scientific Inc., Merck KGaA, Promega Corp., Agilent Technologies, GenScript, Takara Holdings Inc., Bio-Rad Laboratories Inc., Qiagen N.V., Lonza and others.

Report Includes:

  • 45 data tables 34 additional tables
  • An overview and in-depth analysis of the global markets for protein expression technologies
  • Analyses of global market trends with data from 2016 and 2017, and projections of compound annual growth rates (CAGRs) through 2022
  • Discussion on perfusion approaches and supporting practices such as continuous bio manufacturing, and digital and model-based controls
  • Identification of key market dynamics and the factors impacting the global market for protein expression and its sub-segments
  • Regional dynamics of the global protein expression market and analysis of trends and opportunities in major regions covering North America, Europe, Asia-Pacific and the rest of the world (ROW)
  • A relevant patent analysis focuses on describing technological trends across periods of time and regions, such as the U.S., Europe and Japan
  • Detailed analysis of the cloning technologies, production of recombinant proteins and problems associated with protein production
  • Assessment of major stakeholders, product portfolios and recent developments and the competitive landscape among market leaders
  • Company profiles of leading global payers, including Agilent Technologies, Bio-Rad Laboratories Inc., Merck KGaA, Promega Corp., GenScript, Thermo Fisher Scientific Inc., and Qiagen N.V.

Table of Contents

Chapter 1: Introduction

  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Scope of Report
  • Information Sources and Methodology
  • Intended Audience
  • Geographic Breakdown
  • Analyst's Credentials
  • BCC Custom Research
  • Related BCC Research Reports

Chapter 2: Summary and Highlights

Chapter 3: Market and Technology Background

  • Market Definition
  • Protein Expression Market Overview
    • Choice of Cell Type
    • Choice of Plasmid
    • Choice of Cell Expression System
  • Introduction to Protein Expression Systems
  • Protein Synthesis Machinery
  • What is Protein Expression?
  • How Proteins Are Made
    • Transcription and Translation
    • Perfusion Approaches and Supporting Practices (e.g., Continuous Bio Manufacturing and Digital and Model-based Controls)
    • Post-translational Modification
  • Cloning Technologies
  • Constitutive and Inducible Promoters Commonly Used in Recombinant Protein Expression Systems
  • Production of Recombinant Proteins
    • Recombinant Protein Expression Methods
    • Why Produce Proteins Recombinantly?
  • Comparison of Expression Systems
    • Post-translational Processing
  • Problems Associated with the Production of Protein
    • Loss of Expression
  • Ongoing Clinical Trials for Protein Expression
  • Market Dynamics
    • Drivers
    • Restraints
    • Opportunities

Chapter 4: Global Market for Protein Expression Systems by Type

  • Introduction
    • Constitutive and Inducible Promoters Commonly Used in Recombinant Protein Expression Systems
    • Characteristics of Various Recombinant Protein Expression Systems
  • Prokaryotic Expression Systems
    • Promoters
    • E. coli Systems
    • Other Prokaryotic Expression Systems
  • Mammalian Cell Expression Systems
    • Mammalian Expression Vectors Characteristics
    • Chinese Hamster Ovary (CHO) Systems
    • Other Mammalian Cell Systems
  • Insect Cell Expression Systems
    • Baculovirus Systems
  • Yeast Expression Systems
    • K. Lactis Systems
    • Saccharomyces Systems
    • Pichia Systems
  • Cell-Free Expression Systems
  • Algal-Based Expression Systems

Chapter 5: Global Market for Protein Expression by Products and Services

  • Overview
  • Reagents
    • Acids and Bases
    • Acrylamides
    • Buffers/Buffer Salts
    • Cell Lysis
    • Detergents
    • General Reagents
    • Labware
    • Protease Inhibitors
    • Solvents
  • Expression Vectors
    • Commonly Used Expression Hosts
  • Competent Cells
  • Instruments
    • Bioreactor Systems
    • Services
    • Protein Expression Services
    • Benefits
    • Specific Services Provided by Organizations

Chapter 6: Global Market for Protein Expression by Application

  • Introduction
    • Medicine
    • Research
    • Biotechnology
  • Therapeutic
    • Traditional Recombinant and Newer Cell Therapies including Stem Cell
  • Industrial
  • Research

Chapter 7: Global Market for Protein Expression by End User

  • Overview
  • Pharmaceutical and Biotechnology Companies
  • Academic Research Institutes
  • Contract Research Organizations
  • Others

Chapter 8: Global Market for Protein Expression by Region

  • North America
    • U.S.
    • Canada
    • Mexico
  • Europe
    • U.K.
    • Germany
    • France
    • Rest of Europe
  • Asia-Pacific
    • China
    • Japan
    • Australia
    • India
    • South Korea
    • Taiwan
    • Rest of Asia
  • ROW
    • Brazil
    • Saudi Arabia
    • South Africa
    • Others

Chapter 9: Government Regulations

  • General Manufacturing Guidelines
  • Control of Starting/Source Materials
    • Expression Vector and Host Cell
    • Cell Bank System
    • Cell Culture Medium/Other Materials
  • Control of the Manufacturing Process
    • Cell Culture
    • Purification
  • Control of Drug Substance and Drug Product
    • Characterization
    • Routine Control

Chapter 10: Patent Review

  • Patent Analysis
  • Patents and Patent Applications Filed by Institutions

Chapter 11: Competitive Landscape

  • Acquisition
    • Thermo Fisher Scientific Acquired Affymetrix
  • Product Launches

Chapter 12: Company Profiles

  • ABNOVA (TAIWAN) CORP.
  • ACCELAGEN INC.
  • AGILENT TECHNOLOGIES INC.
  • BIOMATIK
  • BIO-RAD LABORATORIES INC.
  • DOMAINEX LTD.
  • ENZO LIFE SCIENCES INC.
  • EXON BIOSYSTEMS
  • GENSCRIPT
  • LONZA GROUP AG
  • LUCIGEN CORP.
  • MERCK KGAA
  • NEW ENGLAND BIOLABS INC.
  • NOVOPROTEIN SCIENTIFIC INC.
  • ORIGENE TECHNOLOGIES INC.
  • OXFORD EXPRESSION TECHNOLOGIES LTD.
  • PROMEGA CORP.
  • PROTEOGENIX INC.
  • QIAGEN INC.
  • R&D SYSTEMS INC.
  • SINO BIOLOGICAL INC.
  • SYNGENE
  • SYNTHETIC GENOMICS INC.
  • TAKARA HOLDINGS, INC.
  • THERMO FISHER SCIENTIFIC INC.

Chapter 13: Appendix: Uses of Protein Expressions Systems

List of Tables

  • Summary Table: Global Market for Protein Expression, by Region, Through 2022
    • Table 1: Advantages and Disadvantages of Protein Expression Systems
    • Table 2: Prokaryotes vs. Eukaryotes Protein Synthesis
    • Table 3: Comparison of Expression Systems
    • Table 4: Ongoing Clinical Trials (List 1)
    • Table 5: Ongoing Clinical Trials (List 2)
    • Table 6: Global Market for Protein Expression Systems, by Type, Through 2022
    • Table 7: Comparison of Protein Expression Systems and Their Respective Advantages and Disadvantages
    • Table 8: Uses of Constitutive and Inducible Promoters in Recombinant Protein Expression Systems
    • Table 9: Advantages, Challenges and Most Common Applications of Protein Expression Systems
    • Table 10: Global Market for Prokaryotic Expression Systems, by Region, Through 2022
    • Table 11: Overview of E. coli Promoter Systems Useful for Heterologous Protein Production
    • Table 12: Bacterial Strains for Protein Expression
    • Table 13: Global Market for Mammalian Cell Expression System, by Region, Through 2022
    • Table 14: Global Market for Insect Cell Expression Systems, by Region, Through 2022
    • Table 15: Global Market for Yeast Expression System, by Region, Through 2022
    • Table 16: Global Market for Cell-Free Systems, by Region, Through 2022
    • Table 17: Global Market for Algal Expression Systems, by Region, Through 2022
    • Table 18: Global Market for Protein Expression, by Products and Services, Through 2022
    • Table 19: Global Market for Reagents, by Region, Through 2022
    • Table 20: Products: Acids and Bases
    • Table 21: Products: Acrylamides
    • Table 22: Products: Buffers/Buffer Salts
    • Table 23: Products: Cell Lysis
    • Table 24: Products: Detergents
    • Table 25: Products: General Reagents
    • Table 26: Products: Labware
    • Table 27: Products: Protease Inhibitors
    • Table 28: Products: Solvents
    • Table 29: Global Market for Vector Products, by Region, Through 2022
    • Table 30: Characteristics of the Commonly Used Expression Hosts
    • Table 31: Global Market for Competent Cells Products, by Region, Through 2022
    • Table 32: Features of Component Cells
    • Table 33: Global Market for Instruments, by Region, Through 2022
    • Table 34: Global Market for Services, by Region, Through 2022
    • Table 35: Specific Services Provided by Organizations
    • Table 36: GenScript Services by Category of Protein Expression
    • Table 37: Global Market for Protein Expression, by Application, Through 2022
    • Table 38: Global Market for Therapeutic Applications, by Region, Through 2022
    • Table 39: Global Market for Industrial Applications, by Region, Through 2022
    • Table 40: Global Market for Research Applications, by Region, Through 2022
    • Table 41: Global Market for Protein Expression, by End User, Through 2022
    • Table 42: Global Market for Pharmaceutical End Users of Protein Expression, by Region, Through 2022
    • Table 43: Global Market for Academic Research Institute End Users of Protein Expression, by Region, Through 2022
    • Table 44: Global Market for Contract Research Organization End Users of Protein Expression, by Region, Through 2022
    • Table 45: Global Market for Other End Users of Protein Expression, by Region, Through 2022
    • Table 46: Global Market for Protein Expression, by Region, Through 2022
    • Table 47: North American Market for Protein Expression, by Country, Through 2022
    • Table 48: North American Market for Protein Expression, by Products, Through 2022
    • Table 49: North American Market for Protein Expression Systems, by Type, Through 2022
    • Table 50: North American Market for Protein Expression, by Application, Through 2022
    • Table 51: North American Market for Protein Expression, by End User, Through 2022
    • Table 52: European Market for Protein Expression, by Country, Through 2022
    • Table 53: European Market for Protein Expression, by Products and Services, Through 2022
    • Table 54: European Market for Protein Expression Systems, by Type, Through 2022
    • Table 55: European Market for Protein Expression, by Application, Through 2022
    • Table 56: European Market for Protein Expression, by End User, Through 2022
    • Table 57: Asia-Pacific Market for Protein Expression, by Country, Through 2022
    • Table 58: Asia-Pacific Market for Protein Expression, by Products and Services, Through 2022
    • Table 59: Asia-Pacific Market for Protein Expression Systems, by Type, Through 2022
    • Table 60: Asia-Pacific Market for Protein Expression, by Application, Through 2022
    • Table 61: Asia-Pacific Market for Protein Expression, by End User, Through 2022
    • Table 62: ROW Market for Protein Expression, by Country, Through 2022
    • Table 63: ROW Market for Protein Expression, by Products and Services, Through 2022
    • Table 64: ROW Market for Protein Expression Systems, by Type, Through 2022
    • Table 65: ROW Market for Protein Expression, by Application, Through 2022
    • Table 66: ROW Market for Protein Expression, by End User, Through 2022
    • Table 67: Significant U.S. Patents and Patent Applications on Protein Expression, 2015-2018
    • Table 68: Significant European Patents and Patent Applications on Protein Expression, 2015-2018
    • Table 69: Significant Japanese Patents and Patent Applications on Protein Expression, 2015-2018
    • Table 70: U.S. Patents Filed on Protein Expression Technologies by Institutions, 2015-2018
    • Table 71: Abnova (Taiwan) Corp. Products
    • Table 72: Biomatik Products
    • Table 73: GenScript Products
    • Table 74: Lucigen Products
    • Table 75: Protein Production Service in HEK293 Cells
    • Table 76: Protein Production Service in E. coli Cells
    • Table 77: Protein Production Service in Insect Cell Culture/Baculovirus Expression
    • Table 78: CHO Cell Transient Transfection Service

List of Figures

  • Summary Figure: Global Market for Protein Expression, by Region, 2016-2022
    • Figure 1: Protein Expression Workflow
    • Figure 2: Share of Clinical Trials Performed for Protein Expression, by Region, 2009-2018
    • Figure 3: Patents Shares of Protein Expression Technologies, by Region, 2015-2018