表紙
市場調查報告書

高通量篩檢 (HTS):技術和全球市場

High-Throughput Screening: Technologies and Global Markets

出版商 BCC Research 商品編碼 773868
出版日期 內容資訊 英文 214 Pages
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高通量篩檢 (HTS):技術和全球市場 High-Throughput Screening: Technologies and Global Markets
出版日期: 2019年01月11日內容資訊: 英文 214 Pages
簡介

全球高通量篩檢 (HTS)市場規模,預測將從2018年的144億美元達到2023年的211億美元,預計在預測期間內將以7.9%的年複合成長率 (CAGR) 成長。

本報告提供全球高通量篩檢 (HTS)市場相關調查分析,產業分析,世界市場趨勢分析與年複合成長率預測,各市場區隔的市場潛在性的特徵化、定量化,政府的法規、技術更新、經濟要素等造成的影響分析,相關專利分析,及主要企業簡介等資訊。

第1章 簡介

第2章 摘要和亮點

第3章 市場、技術背景

  • 市場趨勢
  • 高通量篩檢的演進
  • 顯微鏡、成像技術概要
  • HTS的人工智能、自動化設備
  • 技術進步
  • 技術趨勢
  • 市場動態

第4章 市場分析:各檢測方法

  • 光譜學
  • 質譜分析 (MS) 法
  • 層析法
  • 熱量檢測法
  • X光曲折法
  • 顯微鏡法

第5章 市場分析:各零件

  • 設備/平台
  • 消耗品:試劑、套件
  • 軟體、分析 (生物資訊學)
  • 服務

第6章 市場分析:各技術

  • 細胞化驗分析
  • LoC (實驗室晶片)
  • UHTS
  • 免標定技術

第7章 市場分析:各終端用戶

  • 醫藥品、生物科技企業
  • 研究、政府機關
  • 實驗室、病理學設施
  • CRO

第8章 市場分析:各用途

  • 藥物研發
  • 生物活性化合物篩檢
  • 基因學
  • DNA篩檢
  • 蛋白質分析
  • 微陣列篩檢
  • 毒性實驗
  • 化合物分析

第9章 市場分析:各地區

  • 北美
  • 歐洲
  • 亞太地區
  • 其他 (RoW)

第10章 專利分析、新開發

  • 新技術
  • 專利分析
  • 新開發

第11章 市場機會分析

  • 主要供應商、製造商定位、策略
  • 主要企業
    • Albany Molecular Research Inc.
    • PerkinElmer Inc.
    • Bio-Rad Laboratories Inc.
    • Thermo Fisher Scientific Inc.
  • 一次策略分析
  • R&D活動

第12章 企業簡介

  • AGILENT TECHNOLOGIES INC.
  • ALBANY MOLECULAR RESEARCH INC.
  • AURELIA BIOSCIENCE LTD.
  • AXXAM SPA
  • BECTON, DICKINSON AND CO.
  • BIO-RAD LABORATORIES INC.
  • BIOTEK INSTRUMENTS INC.
  • CARL ZEISS AG
  • CELL SIGNALING TECHNOLOGY INC.
  • CHARLES RIVER LABORATORIES INC.
  • CORNING INC.
  • CREATIVE BIOLABS INC.
  • CURIOX BIOSYSTEMS PTE LTD.
  • CYTOO SA
  • DANAHER CORP.
  • DE NOVO SOFTWARE
  • EUROFINS DISCOVERX CORP.
  • EVOTEC AG
  • FLUXION BIOSCIENCES INC.
  • GE HEALTHCARE
  • GENEDATA AG
  • HUDSON ROBOTICS INC.
  • INSTRUMENT SYSTEMS GMBH
  • INTELLICYT CORP.
  • MILLIPORESIGMA
  • MOLECULAR DEVICES LLC
  • NEMAMETRIX INC.
  • nikon'insutekku
  • Olympus
  • PERKINELMER INC.
  • PHENOVISTA BIOSCIENCES LLC
  • PLATYPUS TECHNOLOGIES
  • SYSMEX CORP.
  • TECAN GROUP LTD.
  • THERMO FISHER SCIENTIFIC INC.
  • TTP LABTECH LTD.
  • VALA SCIENCES INC.
目錄
Product Code: PHM205A

Report Highlights:

The global high-throughput screening (HTS) market should reach $21.1 billion by 2023 from $14.4 billion in 2018 at a compound annual growth rate (CAGR) of 7.9% for the period 2018-2023.

North America as a segment of the global HTS market is expected to grow from $5.2 billion in 2018 to $7.7 billion in 2023 at a CAGR of 8.0% for the period 2018-2023.

APAC as a segment of the global HTS market is expected to grow from $4.2 billion in 2018 to $6.5 billion in 2023 at a CAGR of 13.5% for the period 2018-2023.

Report Scope:

The HTS market has significant potential due to the rising demand for drug discovery, DNA sequencing, toxicity studies and genomics applications. The capabilities and possibilities of market growth increase with new technologies and technological advancement. Emerging economies such as China, India, Latin American and Eastern Europe are considered lucrative regions that are creating opportunities and scope for the HTS market. Significant investments and funding are coming from government and private ventures, research institutes and universities to explore the potential of this market.

The scope of this study includes the current market for drug discovery, protein analysis, biological active compound screening and compound profiling. The report also includes regulations, recent developments, market projections, the competitive landscape and market share. An analysis of patents, clinical trials, innovations, opportunities and the latest trends are also discussed in the report. The report explains the key trends of HTS technologies and applications in regions around the world. It also discusses the market determinants that act as motivating and restraining factors and provides insights to stakeholders and potential entrants. The report will be a key decision-making tool for government organizations, researchers, private players, angel investors, potential entrants and so forth.

Report Includes:

  • 60 data tables and 30 additional tables
  • An industry analysis of technologies and global markets for the high-throughput screening (HTS) within the industry
  • Analyses of global market trends with data from 2017 to 2018, and projections of compound annual growth rates (CAGRs) through 2023
  • Characterization and quantification of the market potential for HTS by geographical regions, technology types, detection methods, components, application segments and end-use industries
  • A look at the influence of government regulations, technological updates and the economic factors augmenting the growth of the market
  • Relevant patent analysis within the global HTS market
  • Company profiles of the major market players and their corporate profiles, including Agilent Technologies Inc., Bio-Rad Laboratories Inc., Danaher Corp., GE Healthcare, Nikon Instruments Inc., PerkinElmer Inc., Sysmex Corp. and Thermo Fisher Scientific Inc.

Table of Contents

Chapter 1: Introduction

  • Study Goals and Objectives
  • Intended Audience
  • Scope of Report
  • Information Sources
  • Methodology
  • Geographic Breakdown
  • Analyst's Credentials
  • BCC Custom Research
  • Related BCC Research Reports

Chapter 2: Summary and Highlights

Chapter 3: Market and Technology Background

  • Market Trends
    • North America Dominates the Market
    • Significant Growth in APAC
    • Major Opportunities for Software and Bioinformatics
  • Evolution of High-Throughput Screening
    • Miniaturization of Assays for High-Throughput Screening
    • Optimization of High-Throughput Screening
    • Traditional and Novel Targets for Lead Discovery
    • HTS Milestones Since Inception
    • Conclusion
  • Overview of Microscope and Imaging Technologies
    • Scanning Probe Microscopy
    • Scanning Electron Microscopy
    • Transmission Electron Microscopy
  • Artificial Intelligence and Automated Devices in HTS
  • Technological Advancements
    • Cytometers
    • Detectors and Sensors
    • Liquid Handling Instruments
  • Technological Trends
    • Label-Free Technology
    • Microplate Technologies
    • Automation and Miniaturization
    • Microfluidics
  • Market Dynamics
    • Market Drivers
    • Market Opportunities
    • Limitations and Challenges

Chapter 4: Market Breakdown by Detection Method

  • Spectroscopy
    • Fluorescence Spectroscopy
    • Total Internal Reflection Fluorescence (TIRF)
    • Nuclear Magnetic Resonance (NMR)
    • Fourier Transformed Infrared (FTIR)
    • Light Scattering
  • Mass Spectrometry (MS)
    • Imaging Mass Spectrometry
    • MALDI Mass Spectrometry
    • Secondary Ion Mass Spectrometer
    • Mass Spectrometry Instruments
  • Chromatography
    • Gas Chromatography
    • Thin-Layer Chromatography
    • Liquid Chromatography
    • Ion Exchange Chromatography
    • Affinity Chromatography
    • Reversed-Phase Chromatography
    • Hydrophobic Interaction Chromatography
  • Calorimetry
    • Isothermal Titration Calorimetry
    • Differential Scanning Calorimetry
  • X-ray Diffraction
  • Microscopy

Chapter 5: Market Breakdown by Component

  • Instruments/Platforms
    • Imaging Devices
    • Microplate Readers
    • Cytometers
    • Liquid Handling Instruments
  • Consumables: Reagents and Kits
  • Software and Analytics (Bioinformatics)
    • ProMass Deconvolution Software by Thermo Fisher Scientific
  • Services
    • ADME Screening
    • SiRNA Screening

Chapter 6: Market Breakdown by Technology

  • Cell-Based Assays
  • Lab-on-a-Chip
  • Ultra-High-Throughput Screening
  • Label-Free Technology

Chapter 7: Market Breakdown by End User

  • Pharmaceutical and Biotechnology Companies
  • Research and Government Institutes
  • Lab and Pathology Facilities
  • Contract Research Organizations

Chapter 8: Market Breakdown by Application

  • Drug Discovery
  • Biological Active Compound Screening
  • Genomics Application
  • DNA Sequencing
  • Protein Analysis
  • Microarray Screening
  • Toxicity Studies
  • Compound Profiling

Chapter 9: Market Breakdown by Region

  • North America
    • United States
    • Canada
  • Europe
    • United Kingdom
    • Germany
    • France
    • Spain
    • Italy
    • Rest of Europe
  • Asia-Pacific
    • India
    • Japan
    • China
    • Rest of APAC
  • Rest of the World
    • Middle East
    • Africa
    • Latin America

Chapter 10: Patent Analysis and New Developments

  • New Technologies
    • DNA-Encoded Libraries
    • High-Throughput Screening with CRISPR-Cas9 and RNAi
    • High-Throughput Screening Using Artificial Intelligence and Machine Learning
    • High-Throughput Screening in Academia for Biomedical Research
    • Advances in Zebrafish High-Throughput Screening Technologies
    • Evolution of Ultra-High-Throughput Screening
  • Patent Analysis
  • New Developments
    • New Product Development

Chapter 11: Analysis of Market Opportunities

  • Key Supplier and Manufacturer Positioning and Strategy
  • Key Market Players in the High-Throughput Screening Market
    • Albany Molecular Research Inc.
    • PerkinElmer Inc.
    • Bio-Rad Laboratories Inc.
    • Thermo Fisher Scientific Inc.
  • Analysis of Primary Strategies
  • Research and Development Activities

Chapter 12: Company Profiles

  • AGILENT TECHNOLOGIES INC.
  • ALBANY MOLECULAR RESEARCH INC.
  • AURELIA BIOSCIENCE LTD.
  • AXXAM SPA
  • BECTON, DICKINSON AND CO.
  • BIO-RAD LABORATORIES INC.
  • BIOTEK INSTRUMENTS INC.
  • CARL ZEISS AG
  • CELL SIGNALING TECHNOLOGY INC.
  • CHARLES RIVER LABORATORIES INC.
  • CORNING INC.
  • CREATIVE BIOLABS INC.
  • CURIOX BIOSYSTEMS PTE LTD.
  • CYTOO SA
  • DANAHER CORP.
  • DE NOVO SOFTWARE
  • EUROFINS DISCOVERX CORP.
  • EVOTEC AG
  • FLUXION BIOSCIENCES INC.
  • GE HEALTHCARE
  • GENEDATA AG
  • HUDSON ROBOTICS INC.
  • INSTRUMENT SYSTEMS GMBH
  • INTELLICYT CORP.
  • MILLIPORESIGMA
  • MOLECULAR DEVICES LLC
  • NEMAMETRIX INC.
  • NIKON INSTRUMENTS INC.
  • OLYMPUS CORP.
  • PERKINELMER INC.
  • PHENOVISTA BIOSCIENCES LLC
  • PLATYPUS TECHNOLOGIES
  • SYSMEX CORP.
  • TECAN GROUP LTD.
  • THERMO FISHER SCIENTIFIC INC.
  • TTP LABTECH LTD.
  • VALA SCIENCES INC.

List of Tables

  • Summary Table: Global Market for High-Throughput Screening, by Region, Through 2023
    • Table 1: Microscope Manufacturers Using HTS, 2018
    • Table 2: Automated Microplate Handling Systems in High-Throughput Screening
    • Table 3: R&D Spending of Major Pharmaceutical Companies, 2013
    • Table 4: R&D Spending in Pharmaceuticals, by Select OECD Countries, 2011-2012
    • Table 5: Uses of High-throughput Platforms for Investigating Stem Cell Microenvironments
    • Table 6: Comparison of High-Throughput Screening Microscopes, 2018
    • Table 7: Global Market for High-Throughput Screening, by Detection Method, Through 2023
    • Table 8: Global Market for Spectroscopy, by Region, Through 2023
    • Table 9: Microplate Reader Products of BMG Labtech, with Detection Method
    • Table 10: Global Market for Mass Spectrometry, by Region, Through 2023
    • Table 11: Global Market for Chromatography, by Region, Through 2023
    • Table 12: Chromatographers Available in the Market
    • Table 13: Typical Applications for Predictor 96-Well Plates
    • Table 14: Gas Chromatography Instruments, by Shimadzu Corp. for High-Throughput Screening
    • Table 15: High-Performance Liquid Chromatography Systems
    • Table 16: Global Market for Calorimetry, by Region, Through 2023
    • Table 17: DCS Products Example
    • Table 18: Global Market for X-Ray Diffraction, by Region, Through 2023
    • Table 19: Select Available Products
    • Table 20: Global Market for Microscopy, by Region, Through 2023
    • Table 21: Global Market for High-Throughput Screening, by Component, Through 2023
    • Table 22: Global Market for Instruments/Platform, by Segment, Through 2023
    • Table 23: Global Market for Instruments and Platforms, by Region, Through 2023
    • Table 24: High-Throughput Screening Instruments
    • Table 25: Cytometers on the Market
    • Table 26: Automated Liquid Handling Modules on the Market
    • Table 27: Global Market for Consumables, by Region, Through 2023
    • Table 28: Global Market for Software and Analytics, Through 2023
    • Table 29: Global Market for High-Throughput Screening, by Region, Through 2023
    • Table 30: Global Market for High-Throughput Screening, by Technology, Through 2023
    • Table 31: Global Market for Cell-Based Assays, by Region, Through 2023
    • Table 32: Types of Cell-Based Assays Used in High-Throughput Screening for Drug Discovery
    • Table 33: Examples of Cell-Based Assays for High-Throughput Screening
    • Table 34: Global Market for Lab-on-a-Chip, by Region, Through 2023
    • Table 35: Global Market for Ultra-High-Throughput Screening, by Region, Through 2023
    • Table 36: Global Market for Label-Free Technology, by Region, Through 2023
    • Table 37: Label-Free Technology for High-Throughput Screening
    • Table 38: Global Market for High-Throughput Screening, by End User, Through 2023
    • Table 39: Global Market for Pharmaceutical and Biotechnology Company End Users of High-Throughput Screening, by Region, Through 2023
    • Table 40: Global Market for Research and Government Institute End Users of High-Throughput Screening, by Region, Through 2023
    • Table 41: Research Institutes with High-Throughput Screening Facilities
    • Table 42: Global Market for Lab and Pathology Facility End Users of High-Throughput Screening, by Region, Through 2023
    • Table 43: Global Market for Contract Research Organization End Users of High-Throughput Screening, by Region, Through 2023
    • Table 44: Global Market for High-Throughput Screening, by Application, Through 2023
    • Table 45: Global Market for Drug Discovery Applications of High-Throughput Screening, by Region, Through 2023
    • Table 46: Global Market for Biological Active Compound Screening Applications of High- Throughput Screening, by Region, Through 2023
    • Table 47: Global Market for Genomics Applications of High-Throughput Screening, by Region, Through 2023
    • Table 48: Global Market for DNA Sequencing Applications of High-Throughput Screening, by Region, Through 2023
    • Table 49: Global Market for Protein Analysis Applications of High-Throughput Screening, by Region, Through 2023
    • Table 50: Global Market for Microarray Applications of High-Throughput Screening, by Region, Through 2023
    • Table 51: Global Market for the Application of High-Throughput Screening in Toxicity Studies, by Region, Through 2023
    • Table 52: Global Market for Compound Profiling Applications of High-Throughput Screening, by Region, Through 2023
    • Table 53: Global Market for High-Throughput Screening, by Region, Through 2023
    • Table 54: North American Market for High-Throughput Screening, by Country, Through 2023
    • Table 55: North American Market for High-Throughput Screening, by Technology, Through 2023
    • Table 56: North American Market for High-Throughput Screening, by Component, Through 2023
    • Table 57: North American Market for High-Throughput Screening, by End User, Through 2023
    • Table 58: North American Market for High-Throughput Screening, by Application, Through 2023
    • Table 59: North American Market for High-Throughput Screening, by Detection Method, Through 2023
    • Table 60: Total Pharmaceutical Business R&D Expenditures, 2011-2015
    • Table 61: European Market for High-Throughput Screening, by Country, Through 2023
    • Table 62: European Market for High-Throughput Screening, by Technology, Through 2023
    • Table 63: European Market for High-Throughput Screening, by Component, Through 2023
    • Table 64: European Market for High-Throughput Screening, by End User, Through 2023
    • Table 65: European Market for High-Throughput Screening, by Application, Through 2023
    • Table 66: European Market for High-Throughput Screening, by Detection Method, Through 2023
    • Table 67: Asia-Pacific Market for High-Throughput Screening, by Country, Through 2023
    • Table 68: Asia-Pacific Market for High-Throughput Screening, by Technology, Through 2023
    • Table 69: Asia-Pacific Market for High-Throughput Screening, by Component, Through 2023
    • Table 70: Asia-Pacific Market for High-Throughput Screening, by End User, Through 2023
    • Table 71: Asia-Pacific Market for High-Throughput Screening, by Application, Through 2023
    • Table 72: Asia-Pacific Market for High-Throughput Screening, by Detection Method, Through 2023
    • Table 73: Vaccine Manufacturers in India
    • Table 74: Clinical Research Institutes in India
    • Table 75: R&D Presence in China of Top 20 Pharmaceutical Companies
    • Table 76: Academic Screening Facilities in China
    • Table 77: RoW Market for High-Throughput Screening, by Technology, Through 2023
    • Table 78: RoW Market for High-Throughput Screening, by End User, Through 2023
    • Table 79: RoW Market for High-Throughput Screening, by Component, Through 2023
    • Table 80: RoW Market for High-Throughput Screening, by Detection Method, Through 2023
    • Table 81: RoW Market for High-Throughput Screening, by Application, Through 2023
    • Table 82: Total Number of Patents in High-Throughput Screening, 2016-2018
    • Table 83: Number of Patents on High-Throughput Screening, by Key Players, 2016-2017
    • Table 84: U.S. Patents on High-Throughput Screening, January 2016 to July 2018
    • Table 85: European Patents on High-Throughput Screening, January 2016 to July 2018
    • Table 86: Japanese Patents on High-Throughput Screening, January 2016 to July 2018
    • Table 87: Company Product Portfolios of High-Throughput Screening Systems
    • Table 88: Albany Molecular Research Subsidiaries and Their Business Activities, 2015-2016
    • Table 89: Innovations and Advancements in Existing Products of Thermo Fisher Scientific, 2018

List of Figures

  • Summary Figure: Global Market for High-Throughput Screening, by Region, 2017-2023
    • Figure 1: High-Throughput Screening Well Specification
    • Figure 2: Triangle of High-Throughput Screening
    • Figure 3: First-Generation High-Throughput Screening, 1993-2000: Throughput
    • Figure 4: Second-Generation High-Throughput Screening, 2001-2006: Efficiency
    • Figure 5: Third-Generation High-Throughput Screening, 2007 Onward: Flexibility
    • Figure 6: Alternative Approaches to Image Sample Surface
    • Figure 7: Top 10 CRO Companies, by Revenue, 2017
    • Figure 8: Global Pharmaceutical R&D Spending, 2009-2015
    • Figure 9: Global Funding for Diseases, 2014-2016
    • Figure 10: GDP Growth Rate of India and China, 2013-2016
    • Figure 11: Components of Mass Spectrometer
    • Figure 12: Advantages of MALDI-TOF instruments
    • Figure 13: Advantages of Thin-Layer Chromatography
    • Figure 14: Features of 1290 Infinity II High-Throughput System
    • Figure 15: Advantages and Disadvantages of Ion Exchange Chromatography
    • Figure 16: Research Challenges for High-Throughput Light Microscope Analysis of Cells and Tissue
    • Figure 17: Features of ProMass Deconvolution Software
    • Figure 18: Features of Trace Finder Software
    • Figure 19: Process of uHTS System
    • Figure 20: Key Pharmaceutical and Biotechnology Companies Providing High-Throughput Screening
    • Figure 21: Drug Discovery Process Using High-Throughput Screening
    • Figure 22: Benefits of High-Throughput Screening in Biological Active Compound Screening
    • Figure 23: Types of Toxicity Studies
    • Figure 24: Strategies to Improve Screening Using Compound Profiling
    • Figure 25: Gross Domestic Spending on Healthcare R&D in North American Countries, 2016
    • Figure 26: U.S. Healthcare Expenditures on R&D, by State, FY 2016
    • Figure 27: Surveillance of Viral Hepatitis in the U.S., 2015
    • Figure 28: Total Health Expenditure Shares in Canada, by Source of Funds, 2016
    • Figure 29: Distribution of Causes of Mortality in Canada, 2017
    • Figure 30: Horizon 2020 Funding, by Sector, 2014-2022
    • Figure 31: European Healthcare Expenditures as a Share of GDP, by Sector, 2015
    • Figure 32: European Healthcare Expenditures, as a Share of GDP, 2015
    • Figure 33: Biotech Funding in the U.K., by Type of Source, 2017
    • Figure 34: Investors in New and Existing Capital Expenditures, 2016
    • Figure 35: Germany's Total Healthcare Spending, 2013-2016
    • Figure 36: R&D Funding in Healthcare Research and the Healthcare Industry, 2016 and 2017
    • Figure 37: Systems Used in High-Throughput Screening Platform at I-Stem
    • Figure 38: Mortality from Cancer in Italy, 2011-2017
    • Figure 39: European Countries with High Cancer Mortality, 2014
    • Figure 40: Indian Healthcare Expenditures, 2004-2014
    • Figure 41: Pharmaceutical R&D Expenditures in Japan, 1995-2015
    • Figure 42: China's Healthcare Expenditures, by Sector, 2016
    • Figure 43: Factors That Allow AMRI To Stay Competitive in The Market
    • Figure 44: PerkinElmer Strategies
    • Figure 45: Strategies Adopted by Key Market Players