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市場調查報告書

胞外體診斷、治療:全球市場

Exosome Diagnostics and Therapeutics: Global Markets

出版商 BCC Research 商品編碼 354591
出版日期 內容資訊 英文 225 Pages
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胞外體診斷、治療:全球市場 Exosome Diagnostics and Therapeutics: Global Markets
出版日期: 2019年05月14日內容資訊: 英文 225 Pages
簡介

全球胞外體診斷、治療的市場在預測期間內預計以39.9%的年複合成長率發展,從2018年的3470萬美元,成長到2023年1億8620萬美元的規模。

本報告提供全球胞外體診斷、治療的市場調查,市場及技術的背景,胞外體定義、零組件,診斷藥、治療藥、試劑、研究工具的胞外體利用的市場機會、潛在性,各終端用戶、地區的市場趨勢,生物醫藥品對市場的影響,專利趨勢,主要的進入經營者,主要經營者的簡介等彙整資料。

第1章 簡介

第2章 摘要、亮點

第3章 市場及技術的背景

  • 胞外體定義、名稱
  • 胞外體的發現
  • 胞外體的零組件
    • DNA
    • 蛋白質
    • RNA
  • 胞外體的分離、檢測
  • 研究、產品開發的生物資訊學資料庫
    • ExoCarta
    • Vesiclepedia
    • EVpedia
  • 胞外體的功能、生理學

第4章 胞外體診斷藥市場

  • 診斷生物標記的外泌體蛋白
  • 診斷生物標記的外泌體核酸
  • 癌症診斷:胞外體為基礎的診斷產品的開發的潛在市場
    • 前列腺癌
    • 乳癌
    • 膀胱癌
    • 卵巢癌
    • 肺癌
  • 液態切片
  • 癌症生物標記的外泌體蛋白、核酸
  • 潛在市場:CNS疾病、神經退化性疾病
  • 潛在市場:感染疾病
  • 潛在市場:心血管疾病
  • 潛在市場:產前診斷
  • 潛在市場:器官移植
  • 進入經營者
  • 市場現狀的評估

第5章 胞外體治療藥市場

  • 胞外體的內因性治療
  • 免疫學的適合性
  • 胞外體的治療藥
    • 來自生物液、細胞培養的胞外體分離、精製
    • 藥物輸送載體的胞外體工程
  • 胞外體的標靶化
  • 合成載體的胞外體設計
  • 胞外體治療市場潛在性
  • 進入經營者
  • 其他的醫藥品、生物科技企業
  • 臨床試驗
  • 市場現狀的評估

第6章 胞外體試劑、研究工具市場

  • 市場概要
    • 分離
    • 檢測研究
    • 表徵分析
    • 工程
    • 其他產品、試劑
  • 進入經營者
  • 市場現狀的評估

第7章 市場分析:各終端用戶

  • 癌症中心
  • 醫院、診斷中心
  • 其他 (製藥&生命科學產業、學術機構)

第8章 市場分析:各地區

  • 北美
  • 歐洲
  • 亞太地區
  • 其他

第9章 胞外體研究:生物醫藥品對市場的影響

  • 生物標記、診斷產業
  • MicroRNA市場
  • 液態切片市場
  • 幹細胞技術市場
  • 產前診斷市場
  • 農業、食品產業
  • 微流體、奈米技術
  • 護膚產業

第10章 專利分析

第11章 市場摘要

第12章 企業簡介

  • CODIAK BIOSCIENCES
  • EVOX THERAPEUTICS LTD.
  • EXOSOME DIAGNOSTICS INC.
  • HANSABIOMED LIFE SCIENCES LTD. (LONZA)
  • NANOSOMIX INC.
  • SYSTEM BIOSCIENCES (SBI)

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目錄
Product Code: BIO149C

Report Highlights:

The global market for exosome diagnostics and therapeutics should grow from $34.7 million in 2018 to $186.2 million by 2023, with a compound annual growth rate (CAGR) of 39.9% for the period of 2018-2023.

Reagents market for exosome diagnostics and therapeutics should grow from $18.3 million in 2018 to $102.3 million by 2023, with a CAGR of 41.1% for the period of 2018-2023.

Instruments market for exosome diagnostics and therapeutics should grow from $13.8 million in 2018 to $70.0 million by 2023, with a CAGR of 38.4% for the period of 2018-2023.

Report Scope:

This report represents a current and important business tool to evaluate new commercial opportunities in the exosome diagnostic, therapeutic and research tool markets. The geographic scope of this study covers the U.S. and companies worldwide. This market is complex and consists of a number of different sectors, each affected differently by scientific and technological development. The report identifies the main positive and negative factors in each sector and forecasts further trends and product and assay development in every category of this industry.

Report Includes:

  • 106 tables
  • An overview of the global market for exosome diagnostics and therapeutics
  • Analyses of global market trends, with data from 2017, 2018, and projections of compound annual growth rates (CAGRs) through 2023
  • Description of immunological compatibility, cargo capabilities and other intrinsic therapeutic activities of exosomes
  • Details of isolation and detection techniques and description of reagents and tools used for exosome research
  • Evaluation of exosomal proteins and nucleic acids as diagnostic biomarkers and discussion of their impact on microRNA, liquid biopsy and stem cell research industry
  • Information on bioinformatics databases for exosome research and product development, including as ExoCarta, Vesiclopedia and Evpedia
  • Company profiles of the prominent players, including Codiak BioSciences, Evox Therapeutics Ltd., Exosome Diagnostics Inc., HansaBioMed Life Sciences Ltd. (Lonza), NonoSomiX Inc., and System Biosciences (SBI)

Table of Contents

Chapter 1: Introduction

  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Scope of Report
  • Information Sources
  • Intended Audience
  • Analyst's Credentials
  • BCC Custom Research
  • Related BCC Research Reports

Chapter 2: Summary and Highlights

Chapter 3: Market and Technology Background

  • Exosome Definition and Nomenclature
  • Discovery of Exosomes
    • Exosomes Biogenesis and Processing
  • Exosome Components
    • DNA in Exosomes
    • Proteins in Exosomes
    • RNA in Exosomes
  • Isolation and Detection of Exosomes
    • Isolation Techniques
    • Exosome Detection
  • Bioinformatic Databases for Exosome Research and Product Development
    • ExoCarta
    • Vesiclepedia
    • EVpedia
  • Exosome Function and Physiology

Chapter 4: Exosome Diagnostic Market

  • Exosomal Proteins as Diagnostic Biomarkers
  • Exosomal Nucleic Acids as Diagnostic Biomarkers
  • Cancer Diagnostics as Market Potential for Exosome-Based Diagnostic Product Development
    • Prostate Cancer as Potential for Diagnostic Development in Exosome Sector
    • Breast Cancer as Potential for Diagnostic Development in Exosome Sector
    • Bladder Cancer as Potential for Diagnostic Development in Exosome Sector
    • Ovarian Cancer as Potential for Diagnostic Development in Exosome Sector
    • Lung Cancer as Potential for Diagnostic Development in the Exosome Sector
  • Liquid Biopsy as Potential for Diagnostics in Exosome Sector
  • Exosomal Proteins and Nucleic Acids as Cancer Biomarkers in Assay Development
  • CNS Disorders and Neurodegeneration Diseases as Market Potential for Exosome Diagnostics Product Development
  • Infectious Diseases as Market Potential for Exosome Diagnostic Product Development
  • Cardiovascular Diseases as Market Potential for Exosome Diagnostic Product Development
  • Prenatal Testing as Market Potential for Exosome Diagnostic Product Development
  • Organ Transplantation as Market Potential for Exosome Diagnostic Product Development
  • Market Participants in Exosome-Based Diagnostics Sector
    • Amarantus BioScience
    • Caris Life Sciences
    • Exosome Diagnostics
    • Exosome Sciences/Aethlon Medical
    • Exosomics Siena SPA
    • NanoSomiX
    • NX Pharmagen
    • NX Prenatal
    • Orion Pharma
    • Sistemic
    • Ymir Genomics
    • Additional Exosome-Based Diagnostic Market Participants
  • Evaluation of Current Diagnostics Sector in Exosome Market

Chapter 5: Exosome Therapeutic Market

  • Intrinsic Therapeutic Activity of Exosomes
  • Immunological Compatibility
  • Cargo Capabilities
  • Generation of Exosome-Mediated Therapeutics
    • Exosome Isolation and Purification from Biofluids or Cell Culture
    • Engineering Exosomes as Therapeutic Delivery Vehicles
  • Targeting Exosomes to Specific Recipient Cells
  • Designing Exosomes as a Synthetic Vector
  • Market Potential for Exosome Therapeutics
  • Market Participants in Exosome-Based Therapeutics Sector
    • Aegle Therapeutics
    • Aethlon Medical
    • Anjarium Biosciences
    • BioRegenerative Sciences
    • Capricor Therapeutics
    • The Cell Factory
    • Codiak BioSciences
    • Creative Medical Technology Holdings (CMTH)
    • DreiRosen Pharma
    • Evox Therapeutics
    • ExoCoBio
    • ExoCyte Therapeutics
    • Exogenus Therapeutics
    • Exopharm
    • Exotech Bio
    • Exovita Biosciences
    • Intrexon Corp.
    • Kimera Labs
    • MDimune
    • MolecuVax
    • Panacea Pharmaceuticals Inc.
    • Paradigm Pharmaceuticals
    • ReCyte
    • Regeneus
    • ReNeuron
    • Therapeutic Solutions International
    • Unicyte AG
    • Additional Pharma and Biotech Companies with Potential Exosome Research Projects
  • Clinical Trials as Indicators for Exosome Market Development
  • Evaluation of Current Therapeutics Sector in Exosome Market

Chapter 6: Exosome Reagents and Research Tools Market

  • Market Overview
    • Isolation Methodologies and Reagents for Exosome
    • Detection Methodologies and Reagents for Exosome Research
    • Characterization Methods and Reagents for Exosome Research
    • Engineering Methods and Reagents for Exosome Research
    • Additional Products and Reagents for Exosome Research
  • Market Participants for Reagents and Tools for Exosome Research
    • 101Bio
    • AMSBIO
    • Cell Guidance Systems
    • Ciloa
    • Evomic Science
    • Excytex
    • ExoCan
    • HansaBioMed (Lonza)
    • IzonScience
    • NanoSight (Malvern Instruments)
    • Nanoview Biosciences
    • System Biosciences (SBI)
    • Additional Market Participants for Reagents and Tools for Exosome Research
  • Evaluation of Current Tools and Reagents in the Exosome Market

Chapter 7: Global Exosome Therapeutic and Diagnostic Market by End User

  • Cancer Institutes
  • Hospital and Diagnostic Centers
    • Exosomal Proteins as Diagnostic Biomarkers
    • Exosome Nucleic Acids as Diagnostics Biomarkers
    • Exosomes: Novel Biomarkers for Clinical Diagnosis
  • Others: Pharmaceutical and Life Science Industries and Academic Institutes

Chapter 8: Market Breakdown by Region

  • North America
  • Europe
  • Asia-Pacific
  • RoW

Chapter 9: Impact of Exosome Research on Specific Biopharmaceutical Market

  • Exosome Research Impact on Biomarker and Diagnostic Industry
  • Exosome Research Impact on MicroRNA Market
  • Exosome Research Impact on the Liquid Biopsy Market
  • Exosome Research Impact on Stem Cell Technologies Market
  • Exosome Research Impact on Prenatal Diagnostic Market
  • Exosome Research Impact on Agriculture and Food Industry
  • Exosome Research, Microfluidics and Nanotechnology
  • Exosome Research Impact on Skincare Industry

Chapter 10: Patent Analysis

  • U.S. Patent Analysis
  • European Patent Analysis
  • Japan Patent Analysis

Chapter 11: Marker Summary

Chapter 12: Company Profiles

  • CODIAK BIOSCIENCES
  • EVOX THERAPEUTICS LTD.
  • EXOSOME DIAGNOSTICS INC.
  • HANSABIOMED LIFE SCIENCES LTD. (LONZA)
  • NANOSOMIX INC.
  • SYSTEM BIOSCIENCES (SBI)

List of Tables

  • Summary Table: Global Market for Exosome Diagnostics and Therapeutics, by Product, Through 2023
    • Table 1: Nomenclature of Exosome Particles
    • Table 2: Publication Trend on the Subject of Exosome, 2003-2017
    • Table 3: Molecules Involved in Exosome Biogenesis and/or Release
    • Table 4: Steps in Exosome Biogenesis and Processing
    • Table 5: Proteins Essential in Exosome Biogenesis and Processing
    • Table 6: Proteins Found in Exosomes
    • Table 7: MicroRNA in Different Bodily Fluids
    • Table 8: Methods for Exosome Isolation
    • Table 9: Distribution of Exosomes Isolation Procedures in the Studies Cataloged in ExoCarta
    • Table 10: Statistics of Data Cataloged in ExoCarta, 2012 and 2017
    • Table 11: Statistics of Data Cataloged in Vesiclepedia, 2012 and 2017
    • Table 12: Statistics of Data Cataloged in EVpedia, 2018
    • Table 13: Comparison of Databases for Exosome Studies
    • Table 14: Examples of Exosomal Proteins for Clinical Diagnostic Applications
    • Table 15: Examples of Exosomal MicroRNA for Clinical Diagnostic Applications
    • Table 16: Characteristic Exosomal MicroRNAs in Various Biological Fluids
    • Table 17: Expression Status of MicroRNAs as the Exosomal Cargo in Different Cancer Types
    • Table 18: Statistics for Prostate Cancer, 2017
    • Table 19: Studies of microRNAs in PCa Patients
    • Table 20: Global Market for Prostate Cancer Diagnostics and Related Cost, 2017 and 2022
    • Table 21: Statistics for Breast Cancer, 2017
    • Table 22: Global Market for Breast Cancer Diagnostics, Through 2023
    • Table 23: Statistics for Bladder Cancer, 2017
    • Table 24: Functions of Exosomal Noncoding RNAs and Proteins in Tumor Metastasis and Invasion
    • Table 25: Global Market for Bladder Cancer Diagnostics, 2017
    • Table 26: Statistics for Ovarian Cancer, 2017
    • Table 27: MicroRNA Content of Ovarian Cancer-Derived Exosomes
    • Table 28: Global Market for Ovarian Cancer Diagnostics, 2017
    • Table 29: Summary of the Predictive Exosomal Components Described Until Now, Including Utility and Values Represented, by Sensitivity
    • Table 30: Statistics for Lung Cancer, 2017
    • Table 31: Global Market for Lung Cancer Diagnostics, 2017
    • Table 32: Liquid vs. Tissue Biopsy
    • Table 33: Global Market for Liquid Biopsy Including Research Tools, Services and Diagnostics, Through 2022
    • Table 34: Exosomal Protein Biomarkers from Bodily Fluids of Patients in Pre-Clinical and Clinical Studies
    • Table 35: Exosomal Nucleic Acid Biomarkers in Pre-Clinical and Clinical Studies
    • Table 36: U.S. Statistics for Alzheimer's, 2017
    • Table 37: Global Market for Alzheimer's Disease Therapeutics and Diagnostics, Through 2023
    • Table 38: Global Statistics for Hepatitis C Infection, 2015
    • Table 39: Estimated Actual New Cases of HAV (Range)
    • Table 40: Global Market for Hepatitis C Diagnostics, 2017
    • Table 41: U.S. Statistics for Cardiovascular Diseases, 2017
    • Table 42: Global Market for Cardiovascular Diagnostics, 2017
    • Table 43: Global Market for Prenatal Diagnostics, Predictive Tests and Neonatal Monitoring, Through 2023
    • Table 44: Global Market for Organ and Tissue Transplantation Products and Devices, Through 2020
    • Table 45: Comparison of Exosome Diagnostics' Approach to Other Liquid Biopsy Platforms
    • Table 46: Main Market Participants in Exosome-Based Diagnostics Sector
    • Table 47: Global Market for Exosome Diagnostics, Through 2023
    • Table 48: Examples of Studies Using Extracellular Vesicles as Drug Delivery Vehicles
    • Table 49: Examples of Engineering Exosome for Cargo Delivery
    • Table 50: Type of Cargo and Loading Method
    • Table 51: Examples of Physiological Effect of Exosome Delivery
    • Table 52: Sales of Top Five Vaccine Providers, 2016
    • Table 53: Age Groups Suffering from Alzheimer's Disease in United States, 2017
    • Table 54: Global Prevalence of Tuberculosis, 2010-2016
    • Table 55: Global Prevalence of Cancer, 2010-2016
    • Table 56: U.S. Statistics for Burn Injuries
    • Table 57: U.S. Statistics for Pressure Ulcer
    • Table 58: Global Market for Aethlon Medical, 2012-2017
    • Table 59: Global Market Revenue, Cost and Profits for Capricor Therapeutics, 2012-2017
    • Table 60: Main Market Participants in Exosome-based Therapeutics Sector
    • Table 61: Examples of Clinical Trials Related to Exosome Research
    • Table 62: Examples of Financing for Exosome-based Therapeutics Companies till 2017
    • Table 63: Global Market for Exosome Therapeutics, Through 2023
    • Table 64: Main Steps in Exosome Research Approach
    • Table 65: Examples of Commercial Kits and Reagents for Exosome Isolation
    • Table 66: Frequency of Use for Each Isolation Technique for Exosome Purification
    • Table 67: Range of Model Options with Zetasizer Nano ZS Instrument
    • Table 68: Examples of Detection Assay
    • Table 69: Examples of Antibody Providers for Exosome Research
    • Table 70: Commercial RNA Extraction Kits
    • Table 71: Percentage of Use of Characterization Techniques for Exosome Sample
    • Table 72: Examples of Purified Exosomes Commercial Products
    • Table 73: Main Market Participants in Exosome Research Tools and Reagents
    • Table 74: Global Market for Exosome Research Tools and Reagents, Through 2023
    • Table 75: Global Market for Exosome Therapeutics and Diagnostics, by End User, Through 2023
    • Table 76: Global Market for Exosomes in Cancer Institute, by Region, Through 2023
    • Table 77: Number of People with Cancer Globally, 2005-2016
    • Table 78: Studies Employing Exosomes without Genetic Modification in Cancer Treatment
    • Table 79: In Vivo and In Vitro Studies Using Modified Exosomes for Cancer Therapy
    • Table 80: Global Market for Exosomes in Hospitals and Diagnostics Centers, by Region, Through 2023
    • Table 81: Exosome Protein in Clinical Diagnostics Applications
    • Table 82: Exosomes: Novel Biomarkers for Clinical Diagnosis
    • Table 83: Global Market for Exosome in Other End User Segment, by Region, Through 2023
    • Table 84: Global Market for Exosome Diagnostics and Therapeutics, by Region, Through 2023
    • Table 85: Leading Cause of Deaths Related to Cancer in UAE, by Cancer Type, 2015
    • Table 86: Leading Causes of Death in Argentina and Percent Change, 2005-2016
    • Table 87: Examples of Protein Markers in Exosomes and Their Related Pathologies
    • Table 88: Examples of MicroRNA Markers in Exosomes and Their Related Pathologies
    • Table 89: Comparison between Liquid Biopsy and Tissue Biopsy
    • Table 90: Global Market for Prenatal Diagnostics, Predictive Tests and Neonatal Monitoring, Through 2023
    • Table 91: U.S. Patents on Exosome Diagnostics and Therapeutics, January 2015-October 2018
    • Table 92: European Patents on Exosome Diagnostics and Therapeutics, January 2015-October 2018
    • Table 93: Japanese Patents on Exosome Diagnostics and Therapeutics, January 2015-October 2018
    • Table 94: Global Market for Exosome Diagnostics and Therapeutics, by Application, Through 2023
    • Table 95: Main Market Participants in Exosome Market
    • Table 96: Product Portfolio: Codiak Biosciences
    • Table 97: Recent Development: Codiak Biosciences 2015 to June 2018
    • Table 98: Product Portfolio: EVOX Therapeutics Ltd.
    • Table 99: Recent Development: EVOX Therapeutics Ltd., 2015 to June 2018
    • Table 100: Product Portfolio: Exosome Diagnostics Inc.
    • Table 101: Recent Developments: Exosome Diagnostics Inc., 2016-2018
    • Table 102: Product Portfolio: HansaBioMed Life Sciences Ltd. (Lonza)
    • Table 103: Recent Developments: HansaBioMed Life Sciences Ltd. (Lonza), 2017
    • Table 104: Product Portfolio: Nanosomix Inc.
    • Table 105: Product Portfolio: System Biosciences (SBI)

List of Figures

  • Summary Figure: Global Market for Exosome Diagnostics and Therapeutics, by Product, 2017-2023
    • Figure 1: Publication Trend on the Subject of Exosome, 2003-2017
    • Figure 2: Differential Centrifugation Process
    • Figure 3: Ciliated Porous Device Designed to Isolate Exosomes, by Filtration
    • Figure 4: Sieving Models for Exosome Filtration
    • Figure 5: Workflow of Mirna-Based Therapeutic Delivery Using Exosomes to Treat Alcoholic Liver Disease
    • Figure 6: Global Market for Exosome Diagnostics, 2017-2023
    • Figure 7: Age Groups Suffering from Alzheimer's Disease in the United States, 2017
    • Figure 8: Global Prevalence of Tuberculosis, 2010-2016
    • Figure 9: Global Prevalence of Cancer, 2010-2016
    • Figure 10: Global Market for Exosome Therapeutics, 2017-2023
    • Figure 11: Global Market for Exosome Research Tools and Reagents, 2016-2023
    • Figure 12: Number of People with Cancer Globally, 2005-2016
    • Figure 13: Global Incidence of Patients with Chronic Diseases, 2005-2030
    • Figure 14: Global Market for Exosome Diagnostics and Therapeutics, by Application, 2017-2023
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