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市場調查報告書

全球數位聚合酵素鏈鎖反應(PCR)技術市場

Digital Polymerase Chain Reaction (PCR) Technology: Global Markets

出版商 BCC Research 商品編碼 305447
出版日期 內容資訊 英文 77 Pages
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全球數位聚合酵素鏈鎖反應(PCR)技術市場 Digital Polymerase Chain Reaction (PCR) Technology: Global Markets
出版日期: 2018年05月23日 內容資訊: 英文 77 Pages
簡介

數位聚合酵素鏈鎖反應(PCR),是已有30年歷史的PCR技術的新應用。其想法為,分離DNA的樣品為微小的液滴,使給定的樣本中的對象DNA數成為0或1,成為具有0或1開關的微晶片。分離樣品並發生各種PCR,由傳統技術檢測PCR。全球數位聚合酵素鏈鎖反應(PCR)技術市場,2012年達8,180萬美元,2013年達1億3,930萬美元的規模。該市場從2013年到2018年5年預計以CAGR(年複合成長率)28.6%擴大,預計擴大為4億8,980萬美元的規模。

本報告提供數位聚合酵素鏈鎖反應(PCR)技術市場相關研究、市場概要,概括數位PCR使用的技術,及相關的樣品,出示數位PCR部門使用的設備及特殊試劑,以及市場實際成果及預測、主要的專利,再加上主要企業簡介。

第1章 簡介

  • 調查的目標和目的
  • 實施調查理由
  • 調查範圍
  • 主要讀者
  • 資訊來源
  • 分析師的簡歷
  • 相關報告
  • BCC線上服務
  • 免除責任

第2章 摘要

  • 產業趨勢
  • 數位PCR的爆炸性成長
  • 設備、樣品區隔中的主要企業
  • LDT的結束
  • 技術課題
  • 癌症及AIDS的治療
  • 更便宜的學術環境
  • 對應PCR問題的解決方案
  • 陡坡的學習曲線

第3章 概要:數位PCR技術的說明

  • 傳統的PCR
    • 對PCR技術的發展和醫療保健產業的影響
    • 設備設計趨勢
    • 傳統PCR VS 即時PCR
    • 分子診斷產業上迅速的發展
    • 產品的創新擴大技術的引進及應用領域
    • 廣泛的用途
    • 市場課題
      • 認知度不足
      • 熟練勞動的必要性
      • 即時PCR器具的高成本
    • 器具選擇條件
    • 數位PCR技術的歷史
    • 技術的功能做法
    • 技術的多樣性
    • 微流體數位PCR
    • 液滴數位PCR
    • 電子束數位PCR
  • 部門
    • 醫藥品/生物科技及臨床開發
    • 臨床診斷
    • 學術機構
    • 其他的部門
  • 用途
    • 腫瘤學
    • HIV
    • 次世代定序
    • 感染疾病
    • 非侵入性診斷
    • SNP檢測
    • 新的用途
    • 摘要

第4章 政府法規

  • 臨床診斷
  • 醫藥品開發
  • 其他的法規上的課題

第5章 各產品市場

  • 消耗品、試劑
  • 設備
  • 企業的展望
    • BIO-RAD
    • RAINDANCE
    • FLUIDIGM
    • LIFE TECHNOLOGIES

第6章 技術

  • 目前預測
  • 主要的專利
  • 主要的領導者
    • Sequenom
    • Rustem Ismagilov (CalTech)
    • Dennis Lo (Chinese University of Hong Kong)
    • Fluidigm
    • Verinata Health
    • Ambergen
    • NuGEN Technologies
    • Ariosa Diagnostics
  • 專利,各分類
  • 專利,各部門
  • 專利,各國
  • 專利,各年度
  • 申請中的專利
  • 專利申請數,各部門
  • 專利申請數,各國
  • 專利申請數,各年度

第7章 與產業結構競爭分析

  • 設備廠商
    • BIO-RAD
    • LIFE TECHNOLOGIES
    • RAINDANCE TECHNOLOGIES
    • FLUIDIGM
    • SYSMEX INOSTICS
  • 消耗品廠商

第8章 研究開發

  • 產業
    • 數位PCR和DNA定序套件
    • 無細胞DNA診斷
  • 學術機構
    • 使用TALEN和CRISPR的遺傳基因編輯
    • 環境及海洋微生物學
  • 技術課題
    • 數位PCR樣品的假陽性
    • BEAMING數位PCR

第9章 企業簡介

  • 454 LIFE SCIENCES CORP.
  • ABBOTT LABORATORIES
  • ADAPTIVE BIOTECHNOLOGIES CORP.
  • ADVANCED LIQUID LOGIC, INC.
  • AFFYMETRIX, INC.
  • AMBERGEN
  • ARIOSA DIAGNOSTICS, INC.
  • AUEON, INC.
  • BERRY GENOMICS CO., LTD.
  • BEXMART
  • BIODX, INC.
  • BIODESY, LLC
  • BIOLOGICAL DYNAMICS, INC.
  • BIO-RAD LABORATORIES, INC.
  • BOREAL GENOMICS CORP.
  • CARIS LIFE SCIENCES, INC.
  • CELULA, INC.
  • COMPLETE GENOMICS
  • ESOTERIX LABORATORY SERVICES, INC.
  • EXACT SCIENCES CORP.
  • FLUIDIGM CORP.
  • GENCELL BIOSYSTEMS, LTD.
  • GENETIC TECHNOLOGIES, LTD.
  • GENOID
  • HALGEN CORP.
  • IMMUMETRIX, LLC
  • INTEGEN X, INC.
  • INTELLIGENT MEDICAL DEVICES, INC.
  • LABORATORY CORPORATION OF AMERICA
  • LIFE CODEXX
  • LOXBRIDGE RESEARCH, LLP
  • LUMINEX CORP.
  • NATERA, INC.
  • NETBIO, INC.
  • NUGEN TECHNOLOGIES, INC.
  • ONCOMED PHARMACEUTICALS, INC.
  • PACIFIC BIOSCIENCES OF CALIFORNIA, INC.
  • POPULATION DIAGNOSTICS, INC.
  • POPULATION GENETICS TECHNOLOGIES, LTD.
  • QUANTERIX CORP.
  • RAINDANCE TECHNOLOGIES, INC.
  • RARECELLS
  • ROCHE DIAGNOSTICS OPERATIONS, INC.
  • SEQUENOM, INC.
  • SEQUENTA, INC.
  • SLIPCHIP CORP.
  • SONY
  • THERMO FISHER SCIENTIFIC
  • TOCAGEN, INC.
  • TOOLGEN, INC.
  • UNITAQ BIO
  • VERINATA HEALTH, INC.
  • VIOMICS, INC.
  • VIPERGEN

圖表

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目錄
Product Code: BIO137B

Report Highlights

The global digital polymerase chain reaction (PCR) technology market totaled $425.0 million in 2017 and is estimated to reach $746.0 million by 2022, growing at a compound annual growth rate (CAGR) of 11.9% for the period of 2017-2022.

Report Includes:

  • 14 data tables and 7 additional tables
  • An overview of the global market for digital polymerase chain reaction (PCR) technology
  • Analyses of global market trends, with data from 2016, and estimates for 2017, and projections of compound annual growth rates (CAGRs) through 2022
  • Discussion of key manufacturers, suppliers, users, and a variety of factors influencing demand
  • Relevant Patent analyses
  • Comprehensive company profiles of major players in the market, including Abbott Laboratories, Celula Inc., Fluidigm Corp., IntegenX Inc. and Stilla Technologies

Report Scope

While this report will discuss applicable complementary technologies, it will not go into the market specifics of these complementary technologies. Of particular note are the majority of reagents used for PCR, as there is significant overlap between the reagents used for digital PCR and those used for real-time PCR. This report will focus on the equipment used for digital PCR, reagents specific to the technology, and any particular applications. There will be significant discussion of the end users, including academia, industry, clinical laboratories, and other users.

Analyst Credentials

Todd Graham is an experienced scientist who has worked in a variety of settings throughout the biotechnology industry for more than 10 years as a key technical resource for a variety of businesses. Among his accomplishments are coordinating the roll out of a new test for a major clinical laboratory services provider, developing pre-clinical and clinical assays in support of pharmaceuticals and medical devices, and being a key team member in developing novel technologies for molecular diagnostics.

Table of Contents

Chapter 1: Introduction

  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Scope of Report
  • Information Sources
  • Methodology
  • Regional Breakdown
  • Analyst's Credentials
  • Related BCC Research Reports

Chapter 2: Summary and Highlights

  • Industry Trends
    • The Marriage of Digital PCR and DNA Sequencing
    • Expansion into Food and Agriculture
    • A Molecular Counting Device
    • Another Weapon in the Cancer Fight
    • Intellectual Property Land Rush

Chapter 3: Overview of Digital PCR Technology

  • History of the Technology
  • How the Technology Works
    • Variations on the Technology
  • Uses
    • Oncology
    • HIV
    • Next-generation Sequencing
    • Infectious Disease
    • Noninvasive Diagnostics
    • Small Nucleotide Polymorphism Detection
    • Single-cell PCR
    • Summary
  • Sectors
    • Pharmaceutical/Biotech and Clinical Development
    • Clinical Diagnostics
    • Academia
    • Forensics
    • Food and Agriculture
    • Environmental Science
  • Industry Structure
    • Equipment Manufacturers
    • Consumable Manufacturers

Chapter 4: Market Breakdown by Technology Type

  • Consumables and Reagents
  • Equipment
  • Company Prospects
    • Bio-Rad
    • Fluidigm
    • Life Technologies
    • Stilla Technologies

Chapter 5: Patent Review/New Developments

  • Key Patents
    • Sandwich Assays in Droplets; Digital Analyte Analysis; and Methods and Compositions for Nucleic Acid Analysis
    • Methods and Devices for Digital PCR
  • Important Patent Applications
    • Digital PCR Systems and Methods Using Digital
    • Quantitating High Titer Samples by Digital PCR
    • Maternal Plasma Transcriptome Analysis by Massively Parallel RNA Sequencing
    • Unitary Biochip Providing Sample-in to Results-out Processing and Methods of Manufacture
    • Single Cell Bar-Coding for Antibody Discovery
    • Methods for Personalizing Cancer Treatment
    • Internal Amplification Control
    • Compositions for Quantitative and/or Semiquantitative Mutation Detection Methods
  • New Patents
  • Research and Development
  • Academia
    • Detection of Human Papillomavirus in Sentinel Lymph Nodes Using Digital PCR
    • Detection of GMO Organisms
    • A Rapid, Accurate and Cost-Effective Method for Identification of Biomarker FcλRIIIa-F158V Genotypes
    • Digital PCR to Time Yeast Cell Development
    • Use of Droplet Digital PCR for Estimation of Fish Abundance and Biomass in Environmental DNA Surveys
    • Digital PCR for the Quantification of Fecal Bacteria in the Water Supply

Chapter 6: Regulatory Analysis

  • Clinical Diagnostics
    • Laboratory-developed Tests
    • U.S. Food and Drug Administration
    • Centers for Medicare and Medicaid Services
    • Health Canada
  • Stance on LDTs for Europe, Australia and China
    • European Medicines Agency
    • Therapeutic Goods Administration (Australia)
    • China Food and Drug Administration
    • Japan Pharmaceutical and Medical Device Agency
  • Pharmaceutical Development
  • Food and Agriculture Regulation
  • Environmental Regulation
  • Forensic Regulation

Chapter 7: Company Profiles

  • About BCC Research

About BCC Research

  • BCC Membership
  • BCC Custom Research

List of Tables

  • Summary Table: Global Market for Digital PCR, by Type, Through 2022 ($ Millions)
    • Table 1: Overview of Digital PCR Technology
    • Table 2: List of Consumables Used in Digital Polymerase Chain Reaction (PCR) Technology
    • Table 3: Global Market for Digital PCR Industry for Consumables, by End User Industry ($ Millions)
    • Table 4: Global Market for Digital PCR Industry Consumables for Pharmaceutical Research and Development, Through 2022 ($ Millions)
    • Table 5: Global Market for Digital PCR Industry Consumables for Noninfectious Disease Clinical Diagnostics, Through 2022 ($ Millions)
    • Table 6: Global Market for Digital PCR Industry Consumables for Academia, Through 2022 ($ Millions)
    • Table 7: Global Market for Digital PCR Industry Consumables for Infectious Disease, Through 2022 ($ Millions)
    • Table 8: Global Market for Digital PCR Industry Consumables for Next-generation Sequencing, Through 2022 ($ Millions)
    • Table 9: Global Market for Digital PCR Industry Consumables for Other Molecular Biology Uses, Through 2022 ($ Millions)
    • Table 10: List of Equipment Used in Digital Polymerase Chain Reaction (PCR) Technology
    • Table 11: Global Market for Digital PCR Industry for Equipment, by End Use Industry, Through 2022 ($ Millions)
    • Table 12: Global Market for Digital PCR Equipment for Pharmaceutical Research and Development, Through 2022 ($ Millions)
    • Table 13: Global Market for Digital PCR Equipment for Noninfectious Disease Clinical Diagnostics, Through 2022 ($ Millions)
    • Table 14: Global Market for Digital PCR Equipment for Academia, Through 2022 ($ Millions)
    • Table 15: Global Market for Digital PCR Equipment for Infectious Disease, Through 2022 ($ Millions)
    • Table 16: Global Market for Digital PCR Equipment for Next-generation Sequencing, Through 2022 ($ Millions)
    • Table 17: Global Market for Digital PCR Equipment for Other Molecular Biology Uses, Through 2022 ($ Millions)
    • Table 18: Key Patents Issued in the Digital PCR Technology Industry, May 2016-April 2017
    • Table 19: Key Patent Applications in the Digital PCR Technology Industry, August 2014-January 2017
    • Table 20: New Patents in the Digital PCR Technology Industry, April 2014-April 2017

List of Figures

  • Summary Figure: Global Market for Digital PCR, by Type, 2016-2022 ($ Millions)
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