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市場調查報告書

生物科技市場調查評論

2019 Biotechnology Research Review

出版商 BCC Research 商品編碼 224399
出版日期 內容資訊 英文 199 Pages
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生物科技市場調查評論 2019 Biotechnology Research Review
出版日期: 2019年11月19日內容資訊: 英文 199 Pages
簡介

本報告提供了BCC Research在2019年發行的生物科技相關報告的8份評論。

第1章 序文

第2章 癌症分析與途徑:技術和全球市場

  • 簡介
  • 大綱與重點
  • 概述
    • 生物標記
    • 篩選測試
    • 癌症早期發現與診斷
    • 途徑分析
    • 透過途徑分析釐清癌症疾病之間的關係
    • 病理學分類
    • 未來目標

第3章 細胞收集的全球市場

  • 簡介
  • 大綱、重點
  • 市場、技術背景
  • 市場主要趨勢
  • 主要建議
  • 阻礙市場成長的要素
  • 市場分析:收集(harvesting)的類型別
    • 自動細胞收集
    • 手動細胞收集
  • 市場分析:終端用戶別
    • 研究機構
    • 生物科技及生物醫藥品企業
    • 醫院、診所
  • 市場分析:用途別
    • 骨髓
    • 脂肪組織
    • 末梢血液
    • 臍帶

第4章 外泌體診斷、治療:全球市場

  • 簡介
  • 大綱、重點
  • 市場概況
    • 外泌體的定義、名稱
    • 外泌體的生物合成、加工
    • 外泌體的組成單元
    • 外泌體中的DNA
    • 外泌體中的蛋白質
    • 外泌體中的RNA
    • 外泌體診斷市場
    • 外泌體治療市場
  • 市場分析:終端用戶別
  • 市場分析:地區別

第5章 DNA解讀、合成、編輯的全球市場

  • 簡介
  • 大綱、重點
  • DNA解讀、合成、編輯技術、市場
    • 大型倡議團體
    • DNA解讀、合成、編輯技術的用途
  • 全球DNA解讀、合成、編輯市場
  • DNA解讀、合成、編輯的用途
  • DNA解讀、合成、編輯的地區別市場
  • 基因組編輯市場
  • 產業成長、影響因素

第6章 DNA測序全球市場:研究、用途、臨床市場

  • 簡介
  • 大綱、重點
  • 技術概要
  • 測序市場
  • 測序的成長促進因素
  • 測序用途
  • 測序產業
  • 市場影響因素

第7章 幹細胞、再生醫學的全球市場

  • 簡介
  • 大綱、重點
  • 技術背景
    • 幹細胞研究中心
    • 幹細胞生產
    • 個別醫療
  • 市場力學
    • 市場成長促進要素
    • 市場成長抑制要素
  • 幹細胞、再生醫學市場分析:產品別
    • 醫學產品
    • 細胞醫療
    • 組織工程
    • 基因治療
    • 細胞銀行
    • 工具、試驗用藥

第8章 蛋白質發現的全球市場

  • 簡介
  • 大綱、重點
  • 技術背景
    • 市場定義
    • 蛋白質發現的市場概要
    • 蛋白質發現系統的簡介
    • 蛋白質發現合成裝置
    • 蛋白質發現是什麼?
    • 蛋白質的製作方法
    • 轉印、翻譯
    • 灌流途徑與實踐方法
    • 翻譯後修飾
    • 複製技術
    • 基改蛋白質發現系統中普遍使用的組成啟動子及誘導啟動子
    • 基改蛋白質的生產
    • 發現系統的比較
    • 蛋白質生產的相關問題
    • 現在實施中的蛋白質發現臨床實驗
  • 全球蛋白質發現系統市場:類型別
  • 全球蛋白質發現系統市場:產品、服務別
  • 全球蛋白質發現系統市場:用途別
  • 全球蛋白質發現系統市場:終端用戶別

第9章 病毒載體、質粒DNA:各種技術及全球市場

  • 簡介
  • 大綱、重點
  • 技術背景
    • 基因治療
    • 質粒生產
    • 市場趨勢
  • 市場力學
  • 市場分析、預測:產品類型別
    • 質粒DNA
    • 病毒載體
  • 市場分析、預測:終端用戶別
    • 研究機構
    • 醫藥品、生物醫藥品企業
  • 市場分析、預測:用途別
    • 癌症
    • 感染症
    • CVD
    • 其他
  • 市場分析、預測:地區別

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目錄
Product Code: BIO069H

Report Highlights:

The global market for cancer profiling technologies should grow from $45.2 billion in 2018 to $90.6 billion by 2023, with a compound annual growth rate (CAGR) of 14.9% for the period of 2018-2023.

The global market for cell harvesting should grow from $885 million in 2018 to $1.5 billion by 2023, with a CAGR of 11.3% for the period of 2018-2023.

The global market for exosome diagnostics and therapeutics should grow from $34.7 million in 2018 to $186.2 million by 2023, with a CAGR of 39.9% for the period of 2018-2023.

Report Scope:

Several significant developments have aided and accelerated the growth of markets in biotechnology, in the period of review. Notable recent advancements in biotechnology are CRISPR, Spheroids for drug development, Quantitative Cell Based Assay using high content analysis platform and Luciferase based high-throughput screening assay. Such technologies assure the wide adoption of cell line technologies for drug development, simplify the gene editing process making it cost-effective.

Companies operating in cell line market are investing huge amount in setting up manufacturing units with advanced state of art facility and expanded production facilities. At the same time, the genetic sequencing technology is advancing at a great pace especially in the healthcare sector in diagnosis of various cancers.

Gene therapy technology has opened new avenues which places emphasis on curing disease that do not have an effective therapeutic availability. Johnson & Johnson, together with the University of Pennsylvania, is developing a third-generation AAV-based gene therapy for Alzheimer's disease. The goal is to use AAV viral delivery to initiate the expression of therapeutic anti-Alzheimer's antibodies in the brain. Novartis launched Zolgensma for the treatment of spinal muscular atrophy. The research represents a novel way to get biologics into the brain to treat Alzheimer's disease and other neurological diseases. This is expected to pave way for further innovations in AAV-based gene therapy.

The sector continuously faces some challenges related to marketing, paying for innovation, pricing pressures from the government organizations.

Paying for development costs is always most critical part for the manufacturers. In 2019, gene therapies and many cell biology technologies are developed to address the needs of some important diseases and proven to be effective. However, this comes for a high cost. For example, Zolgensma, a viral vector based gene therapy for the treatment of spinal muscular atrophy costs around $5 million. It is important to figure out how to pay for the innovation which is quite challenging.

The pricing and paying for getting the products to market are important challenges. The innovation may take several years from clinical trial phase to get launched in the market. The investors may be disappointed if the company doesn't show expected profits and loses the hope while stock prices fall. This means that companies must carefully manage expectations and maintain balance.

Table of Contents

Chapter 1: Foreword

  • Foreword

Chapter 2: Cancer Profiling and Pathways: Technologies and Global Markets (Report Code: BIO073C)

  • Introduction
    • Study Goals and Objectives
    • Reasons for Doing This Study
    • Intended Audience
    • Scope of the Report
    • Methodology
    • Information Sources
    • Analyst's Credentials
    • BCC Custom Research
    • Related BCC Research Reports
  • Summary and Highlights
    • Cancer Profiling and Pathways
  • Introduction to Cancer Profiling Technologies
    • Biomarkers
    • Screening Tests
    • Early Detection and Diagnosis of Cancer
    • Pathway Profiling
    • Molecular Profiling
    • Cancer Profiling
    • Clinical Utility of Molecular Profiling
    • Pathological Classification
    • Cancer Profiling: Future Goals

Chapter 3: Cell Harvesting Market (Report Code: BIO182A)

  • Introduction
    • Study Goals and Objectives
    • Scope of Report
    • Research Methodology and Information Sources
    • Geographic Breakdown
    • Analyst's Credentials
    • Related BCC Research Reports
  • Summary and Highlights
  • Market and Technology Background
  • Key Market Trends
    • Increased Healthcare Spending to Promote the Growth of the Market
    • Manual Cell Harvesting Will Continue to Account for a Significant Share of the Market
    • North America Will Continue to Account for a Significant Share of the Market
    • Emphasis on Innovations in 3D Cell Culture Technology
  • Key Recommendations
    • Shifting Focus toward Small and Medium-Sized Enterprises (SMEs)
    • Increased Number of Partnerships and Collaborations Driving Market Growth
    • Emphasis on Emerging Economies
    • Bone Marrow is the Major Source of Stem Cells Used in Harvesting Procedures
  • Factors Restraining Market Growth
    • High Treatment and Research Costs
  • Market Breakdown by Type of Harvesting
    • Automated Cell Harvesting
    • Manual Cell Harvesting
  • Market Breakdown by End User
    • Research Institutes
    • Biotechnology and Biopharmaceutical Companies
    • Hospitals and Clinics
  • Market Breakdown by Application
    • Bone Marrow
    • Adipose Tissue
    • Peripheral Blood
    • Umbilical Cord

Chapter 4: Exosome Diagnostics and Therapeutics: Global Markets (Report Code: BIO149C)

  • Introduction
    • Study Goals and Objectives
    • Scope of Report
    • Information Sources
    • Intended Audience
    • Analyst's Credentials
    • Related BCC Research Reports
  • Summary and Highlights
  • Market Overview
    • Exosome Definition and Nomenclature
    • Exosomes Biogenesis and Processing
    • Exosome Components
    • DNA in Exosomes
    • Proteins in Exosomes
    • RNA in Exosomes
    • Exosome Diagnostic Market
    • Exosome Therapeutic Market
  • Market Breakdown by End User
  • Market Breakdown by Region

Chapter 5: Global DNA Read, Write and Edit Market (Report Code: BIO193A)

  • Introduction
    • Study Goals and Objectives
    • Reasons for Doing the Study
    • Scope of Report
    • Methodology
    • Information Sources
    • Geographical Breakdown
    • Analyst's Credentials
    • Related BCC Research Reports
  • Summary and Highlights
  • DNA Read, Write and Edit Technologies and Markets
    • Large-Scale Initiatives and Consortia
    • Applications of DNA Read, Write and Edit Technologies
  • DNA Read, Write and Edit Market Driving Forces
  • Global DNA Read, Write and Edit Markets
  • DNA Read, Write and Edit Applications
  • DNA Read, Write and Edit Markets by Region
  • Gene Editing Market
  • Industry Growth-Driving Forces

Chapter 6: Global DNA Sequencing: Research, Applied and Clinical Markets (Report Code: BIO045G)

  • Introduction
    • Study Goals and Objectives
    • Reasons for Doing This Study
    • Scope of Report
    • Information Sources
    • Methodology
    • Geographic Breakdown
    • Analyst's Credentials
    • Related BCC Research Reports
  • Summary and Highlights
  • Overview of Technology
  • Sequencing Markets
  • Sequencing Growth Driving Forces
  • Sequencing Applications
  • Sequencing Industry
  • Market Drivers

Chapter 7: Global Stem Cell and Regenerative Therapy Market: A BCC Research Outlook (Report Code: BIO191A)

  • Introduction
    • Study Goals and Objectives
    • Reasons for Doing This Study
    • Scope of Report
    • Information Sources
    • Methodology
    • Geographic Breakdown
    • Analyst's Credentials
    • Related BCC Research Reports
  • Summary and Highlights
  • Introduction to Technology
    • Stem Cell Research Centers
    • Stem Cell Production
    • Customized Therapy
  • Market Dynamnis
    • Market Drivers
    • Market Restraints
  • Market Breakdown by Product
    • Global Stem Cell and Regenerative Medicines Market, by Product
    • Therapeutic Products
    • Cell Therapies
    • Tissue Engineering
    • Gene Therapy
    • Cell Banking
    • Tools and Reagents

Chapter 8: Protein Expression: Global Markets (Report Code: BIO165A)

  • Introduction
    • Study Goals and Objectives
    • Reasons for Doing This Study
    • Scope of Report
    • Information Sources and Methodology
    • Intended Audience
    • Geographic Breakdown
    • Analyst's Credentials
    • Related BCC Research Reports
  • Summary and Highlights
  • Introduction to Technology
    • Market Definition
    • Protein Expression Market Overview
    • Introduction to Protein Expression Systems
    • Protein Synthesis Machinery
    • What is Protein Expression?
    • How Proteins Are Made?
    • Transcription and Translation
    • Perfusion Approaches and Supporting Practices (e.g., Continuous Bio Manufacturing and Digital and Model-based Controls)
    • Post-translational Modification
    • Cloning Technologies
    • Constitutive and Inducible Promoters Commonly Used in Recombinant Protein Expression Systems
    • Production of Recombinant Proteins
    • Comparison of Expression Systems
    • Problems Associated with the Production of Protein
    • Ongoing Clinical Trials for Protein Expression
  • Global Market for Protein Expression Systems by Type
  • Global Market for Protein Expression by Products and Services
  • Global Market for Protein Expression by Application
  • Global Market for Protein Expression by End User

Chapter 9: Viral Vector and Plasmid DNA: Technologies and Global Markets (Report Code: BIO192A)

  • Introduction
    • Study Goals and Objectives
    • Reasons for Doing This Study
    • Scope of Report
    • Information Sources
    • Methodology
    • Geographic Breakdown
    • Analyst's Credentials
    • Related BCC Research Reports
  • Summary and Highlights
  • Introduction to Technology
    • Gene Therapy
    • Plasmid Production
    • Description of Market Trends
  • Market Dynamics
    • Market Drivers
    • Market Restrictions
    • Opportunity
  • Market Breakdown by Product Type
    • Plasmid DNA
    • Viral Vector
  • Market Breakdown by End User
    • Research Institutes
    • Pharmaceutical and Biopharmaceutical Companies
  • Market Breakdown by Application
    • Cancer
    • Infectious Diseases
    • CVD
    • Other Applications
  • Market Breakdown by Region

List of Tables

  • Table 1: Global Market for Cancer Profiling Technologies, by Type, Through 2023
  • Table 2: Technical Approaches for Tumor Molecular Profiling
  • Table 3: Different Tools for Molecular Profiling of Cancer
  • Table 4: Global Market for Cell Harvesting, by Component/Equipment, Through 2023
  • Table 5: Cost of Stem Cell Therapies, 2017
  • Table 6: Global Market for Cell Harvesting, by Type, Through 2023
  • Table 7: Global Market for Automated Cell Harvesting, by Region, Through 2023
  • Table 8: Global Market for Manual Cell Harvesting, by Region, Through 2023
  • Table 9: Global Market for Cell Harvesting, by End User, Through 2023
  • Table 10: Global Market for Cell Harvesting in Research Institutes, by Region, Through 2023
  • Table 11: Research Institutes in the Cell Harvesting Market
  • Table 12: Global Market for Cell Harvesting in Biotechnology and Biopharmaceutical Companies, by Region, Through 2023
  • Table 13: Global Market for Cell Harvesting in Hospitals and Clinics, by Region, Through 2023
  • Table 14: Hospitals and Clinics in the Cell Harvesting Market
  • Table 15: Global Market for Cell Harvesting, by Procedure, Through 2023
  • Table 16: Global Market for Bone Marrow Cell Harvesting Procedures, by Region, Through 2023
  • Table 17: Types of Bone Marrow Transplants
  • Table 18: Global Market for Adipose Tissue Cell Harvesting Procedures, by Region, Through 2023
  • Table 19: Global Market for Peripheral Blood Cell Harvesting Procedures, by Region, Through 2023
  • Table 20: Examples of Growth Factors Secreted, by Platelets
  • Table 21: Global Market for Umbilical Cord Cell Harvesting Procedures, by Region, Through 2023
  • Table 22: Global Market for Exosome Diagnostics and Therapeutics, by Product, Through 2023
  • Table 23: Nomenclature of Exosome Particles
  • Table 24: Examples of Exosomal Proteins for Clinical Diagnostic Applications
  • Table 25: Examples of Studies Using Extracellular Vesicles as Drug Delivery Vehicles
  • Table 26: Examples of Engineering Exosome for Cargo Delivery
  • Table 27: Global Market for Exosome Therapeutics and Diagnostics, by End User, Through 2023
  • Table 28: Global Market for Exosome Diagnostics and Therapeutics, by Region, Through 2023
  • Table 29: Global Market for DNA Read, Write and Edit, by Application, Through 2024
  • Table 30: Report Scope
  • Table 31: Impact of Large-scale Initiatives on the Read, Write and Edit Industry
  • Table 32: Driving Forces of DNA Read, Write and Edit Industry Growth
  • Table 33: Global Market for DNA Read, Write and Edit, by End User, Through 2024
  • Table 34: Summary of Applications for DNA Read, Write and Edit Technologies
  • Table 35: Global DNA Read, Write and Edit Market, by Region, Through 2024
  • Table 36: Global Market for Gene Editing, by End User, Through 2024
  • Table 37: Driving Forces for Growth in the DNA Read, Write and Edit Industry
  • Table 38: Global Sequencing Market, by Delivered Format, Through 2023
  • Table 39: DNA Report Scope
  • Table 40: Global Sequencing Market, by Product Type, Through 2023
  • Table 41: Global Sequencing Market, by Format, Through 2023
  • Table 42: DNA Sequencing Market Growth Driving Forces
  • Table 43: Sequencing End Users and Applications
  • Table 44: Key Sequencing Industry Participants by Sector
  • Table 45: Sequencing Market Growth Driving Forces
  • Table 46: Global Stem Cell and Regenerative Medicines Market, by Region, Through 2024
  • Table 47: Snapshot of Regenerative Product Pipeline
  • Table 48: Ethical Issues in Different Phases of Stem Cell Research
  • Table 49: Global Stem Cell and Regenerative Medicines Market, by Product, Through 2024
  • Table 50: Global Stem Cell and Regenerative Therapeutic Products Market, by Type, Through 2024
  • Table 51: Global Market for Protein Expression, by Region, Through 2022
  • Table 52: Advantages and Disadvantages of Protein Expression Systems
  • Table 53: Prokaryotes vs. Eukaryotes Protein Synthesis
  • Table 54: Comparison of Expression Systems
  • Table 55: Ongoing Clinical Trials (List 1)
  • Table 56: Ongoing Clinical Trials (List 2)
  • Table 57: Global Market for Protein Expression Systems, by Type, Through 2022
  • Table 58: Global Market for Protein Expression, by Products and Services, Through 2022
  • Table 59: Global Market for Protein Expression, by Application, Through 2022
  • Table 60: Global Market for Protein Expression, by End User, Through 2022
  • Table 61: Types of Gene Therapy
  • Table 62: Clinical Trials for Viral Vector-Mediated Gene Therapy in the U.S., 2018 and 2019
  • Table 63: Partnerships for Viral Vector-Mediated Gene Therapy
  • Table 64: Global Market for Viral Vector and Plasmid DNA, by Product Type, Through 2024
  • Table 65: Global Market for Plasmid DNA, by Region, Through 2024
  • Table 66: Global Market for Viral Vector, by Region, Through 2024
  • Table 67: Global Market for Viral Vector and Plasmid DNA, by End User, Through 2024
  • Table 68: Global Market for Viral Vector and Plasmid DNA in Research Institutes, by Region, Through 2024
  • Table 69: Global Market for Viral Vector and Plasmid DNA in Pharmaceutical and Biopharmaceutical Companies, by Region, Through 2024
  • Table 70: Global Market for Viral Vector and Plasmid DNA, by Application, Through 2024
  • Table 71: Global Market Viral Vector and Plasmid DNA in Cancer, by Region, Through 2024
  • Table 72: Pipeline Products for Cancer Gene Therapy, 2018 and 2019
  • Table 73: Global Market for Viral Vector and Plasmid DNA in Infectious Diseases, by Region, Through 2024
  • Table 74: Gene Transfer Vectors Used in Heart Gene Therapy
  • Table 75: Global Market for Viral Vector and Plasmid DNA in CVD, by Region, Through 2024
  • Table 76: Global Market for Viral Vector and Plasmid DNA in Other Applications, by Region, Through 2024
  • Table 77: Global Market for Viral Vector and Plasmid DNA, by Region, Through 2024

List of Figures

  • Figure 1: Global Market for Cancer Profiling Technologies, by Type, 2017-2023
  • Figure 2: Global Market for Cell Harvesting, by Component/Equipment, 2017-2023
  • Figure 3: Global Market for Exosome Diagnostics and Therapeutics, by Product, 2017-2023
  • Figure 4: Global Market for DNA Read, Write and Edit, by Application, 2017-2024
  • Figure 5: Global Sequencing Market, by Delivered Format, 2017-2023
  • Figure 6: Global Stem Cell and Regenerative Medicines Market Share, by Region, 2018
  • Figure 7: Global Stem Cell and Regenerative Medicines Market Share, by Product, 2018
  • Figure 8: Global Stem Cell and Regenerative Therapeutic Products Market, 2018-2024
  • Figure 9: Global Stem Cell and Regenerative Therapeutic Products Market Share, by Type, 2018
  • Figure 10: Global Cell Therapy Market, 2018-2024
  • Figure 11: Global Tissue Engineering Market, 2018-2024
  • Figure 12: Global Gene Therapy Market, 2018-2024
  • Figure 13: Global Cell Banking Market, 2018-2024
  • Figure 14: Global Tools and Reagents Market, 2018-2024
  • Figure 15: Global Market for Protein Expression, by Region, 2016-2022
  • Figure 16: Protein Expression Workflow
  • Figure 17: Share of Clinical Trials Performed for Protein Expression, by Region, 2009-2018
  • Figure 18: Processes of Gene Therapy Research
  • Figure 19: Processes of Gene Therapy Development
  • Figure 20: Typical Production Process Flow for Viral Vectors
  • Figure 21: Most Common Cancer Types, Global Cases, 2018
  • Figure 22: Progression of cGMP Compliance for Drug Development
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