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市場調查報告書

體外 (in vitro) 毒性實驗:技術和全球市場

In Vitro Toxicity Testing: Technologies and Global Markets

出版商 BCC Research 商品編碼 134604
出版日期 內容資訊 英文 174 Pages
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體外 (in vitro) 毒性實驗:技術和全球市場 In Vitro Toxicity Testing: Technologies and Global Markets
出版日期: 2019年01月17日內容資訊: 英文 174 Pages
簡介

全球體外 (in vitro) 毒性測試市場預計將從2018年的74億美元,到2023年擴大到104億美元。市場在2018年∼2023年間預則將以年複合成長率 (CAGR) 7.1%的速度成長。

本報告提供全球體外 (in vitro) 毒性測試市場調查分析, 市場概要,技術概要,市場趨勢分析與預測,最新趨勢,技術開發,政府的法規,主要企業等相關的系統性資訊。

第1章 簡介

第2章 摘要和亮點

第3章 市場與技術的背景

  • 簡介
  • 法律規範與計劃
  • 主要市場成長要素
  • 機會
  • 限制與課題

第4章 市場明細:各毒性評估項目、實驗

  • ADME
  • 皮膚刺激性,腐蝕,過敏反應
  • 遺傳毒性實驗
  • 細胞毒性實驗
  • 眼毒性
  • 內臟器官毒性
  • 光毒性實驗
  • 皮膚毒性
  • 致癌性
  • 神經毒性
  • 生殖實驗 (DART)
  • 其他毒性評估項目、實驗

第5章 市場明細:各終端用戶產業

  • 製藥、生物科技企業
  • 醫療 (診斷)
  • 食品、飲料產業
  • 化學工業
  • 個人保養用品 (化妝品)
  • 臨床研究委外機構 (CRO)
  • 研究機關

第6章 市場明細:各手法/技術

  • 轉錄體學
  • 蛋白質體學
  • 代謝體學
  • CELLOMICS/Cytomics

第7章 市場明細:各零件

  • 化驗
  • 設備
  • 試劑、套件
  • 軟體
  • 服務

第8章 市場明細:各地區

  • 北美
  • 歐洲
  • 亞太地區
  • 其他

第9章 專利分析/新開發

  • 體外 (in vitro) 毒性實驗用生物標記
  • 競爭情形
  • 專利分析

第10章 企業簡介

  • ABBOTT LABORATORIES, INC.
  • ACEA BIOSCIENCES, INC.
  • AGILENT TECHNOLOGIES, INC.
  • ALBANY MOLECULAR RESEARCH, INC.
  • APTUIT, INC.
  • BIOGNOSYS AG
  • BIORELIANCE
  • BIOVIA
  • CELLULAR DYNAMICS INTERNATIONAL, INC.
  • CHANTEST
  • CHARLES RIVER LABORATORIES
  • COVANCE, INC.
  • CYPROTEX PLC
  • DRIK LLC
  • ENZO LIFE SCIENCES, INC.
  • ESSEN BIOSCIENCE, INC.
  • EUROFINS SCIENTIFIC SE
  • EVOTEC AG
  • GE HEALTHCARE LIFE SCIENCES
  • GENEDATA
  • GENTRONIX LTD.
  • HUREL CORP.
  • IMQUEST BIOSCIENCES, INC.
  • IMSTAR SA
  • INSPHERO AG
  • KIYATEC, INC.
  • LONZA GROUP LTD.
  • METABOLON, INC.
  • MOLECULAR DEVICES LLC
  • PERKINELMER, INC.
  • PROMEGA CORP.
  • QIAGEN NV
  • SGS-SA
  • STEMINA BIOMARKER DISCOVERY, INC.
  • SYNVIVO, INC.
  • THERMO FISHER SCIENTIFIC, INC.
  • VALA SCIENCES, INC.
  • VISTAGEN THERAPEUTICS, INC.
  • XENOMETRIX AG

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目錄
Product Code: PHM017F

Report Highlights:

The global market for in vitro toxicity testing should grow from $7.4 billion in 2018 to reach $10.4 billion by 2023 at a compound annual growth rate (CAGR) of 7.1% for the period of 2018-2023.

European market for in vitro toxicity testing should grow from $2.7 billion in 2018 to reach $3.8 billion by 2023 at a CAGR of 6.9% for the period of 2018-2023.

Asia-Pacific market for in vitro toxicity testing should grow from $2.1 billion in 2018 to reach $3.0 billion by 2023 at a CAGR of 7.6% for the period of 2018-2023.

Report Scope:

The scope of the report encompasses the major types of traditional toxicity testing that have been used, and the in vitro techniques that are being developed by industry, government agencies and nonprofits. It analyzes current market status, examines drivers on future markets and presents forecasts of growth over the next five years.

Technology developments, including the latest trends, are discussed. Other influential factors such as validation and testing strategies for pharmaceuticals, cosmetics, and chemicals also have been included.

Regulatory drivers play a large role in toxicology, determining the specific parameters of tests that have been explicitly required. They also heavily influence the testing that is performed by companies in earlier stages of research. The report examines the regulatory role and the different federal and international agencies that play an active role in in vitro toxicology research, development and adoption.

Report Includes:

  • 52 data table and 18 additional tables
  • An overview of the global markets and technologies for the in vitro toxicity testing techniques within the pharmaceutical industry
  • Analyses of global market trends with data from 2017, 2018, and projections of compound annual growth rates (CAGRs) through 2023
  • Information on latest trends, technological developments and government regulations that influence the growth of the market
  • A breakdown of influential factors, such as validation of the alternative measures for toxicity and toxicity testing strategies for chemicals, pesticides, and food additives
  • Evaluation covering equipment, assays, cells, reagents, and services used in toxicity testing
  • Profiles of major players in the toxicology market, including Abbott Laboratories, Inc., Agilent Technologies, Inc., Evotec AG, GE Healthcare Life Sciences and Thermo Fisher Scientific, Inc.

Table of Contents

Chapter 1: Introduction

  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Intended Audience
  • Scope of Report
  • Information Sources
  • Methodology
  • Geographic Breakdown
  • Analyst's Credentials
  • BCC Custom Research
  • Related BCC Research Reports

Chapter 2: Summary and Highlights

Chapter 3: Market and Technology Background

  • Introduction
  • Regulatory Framework and Programs
    • European Union
    • India
    • Regulatory Programs
  • Key Market Growth Factors
    • Replacement of In Vivo Models, by In Vitro Models
    • In Vitro Toxicity in the Drug Discovery Process
    • CROs Gaining Popularity
    • Application of High-Throughput Screening in Toxicology
  • Opportunities
    • Extensive Funding, by Research Institutes on Toxicology
    • Paradigm Shift in Toxicity Testing in the 21st Century
  • Limitations and Challenges
    • Expensive Equipment Used in Toxicology

Chapter 4: Market Breakdown by Toxicity Endpoints and Tests

  • ADME
    • In Vitro Metabolism Offerings
    • Metabolism Reaction Phenotyping for Genetic Polymorphisms
  • Skin Irritation, Corrosion and Sensitization
  • Genotoxicity Testing
    • In Vitro Micronucleus Test (MNT)
  • Cytotoxicity Testing
    • Use of Cytotoxicity Assays for Acute Toxicity Testing
    • Example of Commercially Available Cytotoxicity Assay Kit
  • Ocular Toxicity
  • Organ Toxicity
  • Phototoxicity Testing
  • Dermal Toxicity
  • Carcinogenicity
    • The AMES Test
  • Neurotoxicity
  • Development and Reproductive Toxicity (DART)
  • Other Toxicity Endpoints and Tests

Chapter 5: Market Breakdown by End-User Industry

  • Pharmaceutical and Biotechnology Companies
  • Healthcare (Diagnosis)
  • Food and Beverage Industry
  • Chemical Industry
    • Challenges for Chemical Companies: Depth and Breadth
  • Personal Care Products (Cosmetics)
  • Contract Research Organizations
  • Research Institutes
    • Center for Alternatives to Animal Testing (CAAT)
    • European Union Reference Laboratory for Alternatives to Animal Testing (EURL)
    • The Hamner Institutes for Health Sciences

Chapter 6: Market Breakdown by Tool/Technology

  • Transcriptomics
    • Tools Used in Transcriptomics
  • Proteomics
    • Proteomics Tools
  • Metabolomics
    • Collaboration for Establishing Metabolomics Lab
    • Metabolomics Tools
  • Cellomics or Cytomics

Chapter 7: Market Breakdown by Component

  • Assays
    • Companies Strategies for the Development of New, and Expansion of Existing Products:
    • Assay Kits for High-Content Screening
    • Cell-Based Assays: Overview and Newer Developments
    • Components of Cell-Based Assay Systems
  • Equipment
  • Reagents and Kits
    • New Reagents in the Market
  • Software and Analytics
    • Trace Finder Software, by Thermo Fisher Scientific, Inc.
  • Services
    • ADME Screening

Chapter 8: Market Breakdown by Region

  • North America
    • United States
    • Recent Developments in the Region
    • Canada
  • Europe
    • United Kingdom
    • Germany
    • France
    • Spain
    • Italy
    • Rest of Europe
  • Asia-Pacific
    • China
    • Japan
    • India
    • Rest of Asia-Pacific
  • Rest of the World
    • Middle East
    • Africa
    • Latin America

Chapter 9: Patent Review/ New Developments

  • Biomarkers for In Vitro Toxicology
    • Uses of In Vitro Biomarkers
    • In Vitro Biomarkers: Future Prospects
    • Types of Biomarkers
  • Competitive Landscape
    • Key Companies
    • Key Market Player Strategies
  • Patent Analysis

Chapter 10: Company Profiles

  • ABBOTT LABORATORIES, INC.
    • Business Overview
  • ACEA BIOSCIENCES, INC.
    • Business Overview
  • AGILENT TECHNOLOGIES, INC.
    • Business Overview
  • ALBANY MOLECULAR RESEARCH, INC.
    • Business Overview
  • APTUIT, INC.
    • Business Overview
  • BIOGNOSYS AG
    • Business Overview
  • BIORELIANCE
    • Business Overview
  • BIOVIA
  • CELLULAR DYNAMICS INTERNATIONAL, INC.
    • Business Overview
  • CHANTEST
    • Business Overview
  • CHARLES RIVER LABORATORIES
    • Business Overview
  • COVANCE, INC.
    • Business Overview
  • CYPROTEX PLC
    • Business Overview
  • DRIK LLC
    • Business Overview
  • ENZO LIFE SCIENCES, INC.
    • Business Overview
  • ESSEN BIOSCIENCE, INC.
    • Business Overview
  • EUROFINS SCIENTIFIC SE
    • Business Overview
    • Products Offered
  • EVOTEC AG
    • Business Overview
  • GE HEALTHCARE LIFE SCIENCES
    • Business Overview
  • GENEDATA
    • Business Overview
  • GENTRONIX LTD.
    • Business Overview
  • HUREL CORP.
    • Business Overview
  • IMQUEST BIOSCIENCES, INC.
    • Business Overview
  • IMSTAR SA
    • Business Overview
  • INSPHERO AG
    • Business Overview
  • KIYATEC, INC.
    • Business Overview
  • LONZA GROUP LTD.
    • Business Overview
    • Products Offered
  • METABOLON, INC.
    • Business Overview
  • MOLECULAR DEVICES LLC
    • Business Overview
  • PERKINELMER, INC.
    • Business Overview
  • PROMEGA CORP.
    • Business Overview
    • Products Offered
  • QIAGEN NV
    • Business Overview
    • Products Offered
  • SGS-SA
    • Business Overview
  • STEMINA BIOMARKER DISCOVERY, INC.
    • Business Overview
  • SYNVIVO, INC.
    • Business Overview
  • THERMO FISHER SCIENTIFIC, INC.
    • Business Overview
  • VALA SCIENCES, INC.
    • Business Overview
  • VISTAGEN THERAPEUTICS, INC.
    • Business Overview
  • XENOMETRIX AG
    • Business Overview

List of Tables

  • Summary Table: Global Market for In Vitro Toxicity Testing, by Region, Through 2023
    • Table 1: Research Institutes/Organizations that Offer In Vitro Testing and Other Services
    • Table 2: Instruments Used in In Vitro Toxicology Testing, 2017
    • Table 3: Global Market for In Vitro Toxicity Testing Technologies, by Toxicity Endpoint and Test, Through 2023
    • Table 4: ADME In Vitro Toxicity Products
    • Table 5: Global Market for ADME Testing Technologies, by Region, Through 2023
    • Table 6: Global Market for Skin Irritation, Corrosion and Sensitization Testing Technologies, by Region, Through 2023
    • Table 7: Genotoxicity Testing Products
    • Table 8: Global Market for Genotoxicity Testing Technologies, by Region, Through 2023
    • Table 9: Global Market for Cytotoxicity Testing Technologies, by Region, Through 2023
    • Table 10: Global Market for Ocular Toxicity Testing Technologies, by Region, Through 2023
    • Table 11: Global Market for Organ Toxicity Testing Technologies, by Region, Through 2023
    • Table 12: Validated Non-animal Methods
    • Table 13: Global Market for Phototoxicity Testing Technologies, by Region, Through 2023
    • Table 14: Global Market for Dermal Toxicity Testing Technologies, by Region, Through 2023
    • Table 15: OECD TGs for In Vitro Genotoxicity and Mutagenicity Testing
    • Table 16: Global Market for Carcinogenicity Testing Technologies, by Region, Through 2023
    • Table 17: General Endpoints Used for In Vitro Neurotoxicity Testing
    • Table 18: Global Market for Neurotoxicity Testing Technologies, by Region, Through 2023
    • Table 19: Global Market for DART Testing Technologies, by Region, Through 2023
    • Table 20: Global Market for Other Toxicity Endpoints and Tests Technologies, by Region, Through 2023
    • Table 21: Global Market for In Vitro Toxicity Testing Technologies, by End-User Industry, Through 2023
    • Table 22: Global Market for Pharmaceutical and Biotechnology End-User Industry, by Region, Through 2023
    • Table 23: Global Market for Healthcare End-User Industry, by Region, Through 2023
    • Table 24: Global Market for Food and Beverage End-User Industry, by Region, Through 2023
    • Table 25: Global Market for Chemical End-User Industry, by Region, Through 2023
    • Table 26: Chemical Companies that Provide Vitro Toxicology Services
    • Table 27: Global Market for Personal Care Products End-User Industry, by Region, Through 2023
    • Table 28: CROs Providing In Vitro Toxicology Services
    • Table 29: Global Market for CROs End-User Industries, by Region, Through 2023
    • Table 30: Global Market for Research Institutes End-User Industries, by Region, Through 2023
    • Table 31: Research Institutes Providing In Vitro Toxicology Tests
    • Table 32: Global Market for In Vitro Toxicology Testing Technologies, by Tool/Technology, Through 2023
    • Table 33: Global Market for Transcriptomics, by Region, Through 2023
    • Table 34: Global Market for Proteomics, by Region, Through 2023
    • Table 35: Global Market for Metabolomics, by Region, Through 2023
    • Table 36: Common Analytical Platforms Used in Metabolomics
    • Table 37: Global Market for Cellomics, by Region, Through 2023
    • Table 38: Global Market for In Vitro Toxicity Testing Technologies, by Component, Through 2023
    • Table 39: Global Market for Assays, by Region, Through 2023
    • Table 40: Global Market for Equipment, by Region, Through 2023
    • Table 41: Global Market for Reagents and Kits, by Region, Through 2023
    • Table 42: Specifications of HCS LIVE?DEAD Green Kit
    • Table 43: Global Market for Software and Analytics, by Region, Through 2023
    • Table 44: Global Market for Services, by Region, Through 2023
    • Table 45: North American Market for In Vitro Toxicity Testing Technologies, by Country, Through 2023
    • Table 46: North American Market for In Vitro Toxicity Testing Technologies, by Toxicity Endpoint/Test, Through 2023
    • Table 47: North American Market for In Vitro Toxicity Testing Technologies, by End-User Industry, Through 2023
    • Table 48: North American Market for In Vitro Toxicity Testing Technologies, by Tools/Technology, Through 2023
    • Table 49: North American Market for In Vitro Toxicity Testing Technologies, by Component, Through 2023
    • Table 50: In Vitro Services Offered by Nucro-Technics
    • Table 51: Tracking System for Alternative Test Methods, Review (TSAR), 2018
    • Table 52: European Market for In Vitro Toxicity Testing Technologies, by Country, Through 2023
    • Table 53: European Market for In Vitro Toxicity Testing Technologies, by Toxicity Endpoint/Test, Through 2023
    • Table 54: European Market for In Vitro Toxicity Testing Technologies, by End-User Industry, Through 2023
    • Table 55: European Market for In Vitro Toxicity Testing Technologies, by Tool/Technology, Through 2023
    • Table 56: European Market for In Vitro Toxicity Testing Technologies, by Component, Through 2023
    • Table 57: Asia-Pacific Market for In Vitro Toxicity Testing Technologies, by Country, Through 2023
    • Table 58: Asia-Pacific Market for In Vitro Toxicity Testing Technologies, by Toxicity Endpoint/Test, Through 2023
    • Table 59: Asia-Pacific Market for In Vitro Toxicity Testing Technologies, by End-User Industry, Through 2023
    • Table 60: Asia-Pacific Market for In Vitro Toxicity Testing Technologies, by Tool/Technology, Through 2023
    • Table 61: Asia-Pacific Market for In Vitro Toxicity Testing Technologies, by Component, Through 2023
    • Table 62: Top 20 R&D Pharmaceutical Companies in China
    • Table 63: Rest of the World Market for In Vitro Toxicity Testing Technologies, by Toxicity Endpoint/Test, Through 2023
    • Table 64: Rest of the World Market for In Vitro Toxicity Testing Technologies, by End-User Industry, Through 2023
    • Table 65: Rest of the World Market for In Vitro Toxicity Testing Technologies, by Tool/Technology, Through 2023
    • Table 66: Rest of the World Market for In Vitro Toxicity Testing Technologies, by Component, Through 2023
    • Table 67: Number of Patents, by Category in Different Countries, January 2016 to July 2018
    • Table 68: Patents, by Key Players, January 2016 to July 2018
    • Table 69: List of Patents Analyzed, January 2016 to July 2018

List of Figures

  • Summary Figure: Global Market for In Vitro Toxicity Testing, by Region, 2017-2023
    • Figure 1: Timeline of Animal Testing Ban in India
    • Figure 2: Regulations timeline for Cosmetic Testing on Animals
    • Figure 3: Comparison Between In Vivo and In Vitro Toxicity
    • Figure 4: Discovery Toxicology
    • Figure 5: Merck KGaA Toxicology Services
    • Figure 6: Global Per Capita Healthcare Expenditure, by Country, 2016
    • Figure 7: In Vitro Toolbox for Acute Inhalation Toxicity
    • Figure 8: Features of ToxiScreen
    • Figure 9: Drug Discovery Process
    • Figure 10: Use of Metabolomics Toxicology
    • Figure 11: Types of Toxicity Studies
    • Figure 12: Features of Thiol Tracker Violet
    • Figure 13: Features of TraceFinder Software
    • Figure 14: Healthcare Expenditures for R&D, by State and Performer, FY 2016
    • Figure 15: Total Health Expenditures, by Source of Finance, 2016
    • Figure 16: Healthcare Expenditure as a Share of GDP, by Region/Country, 2015
    • Figure 17: E.U. Innovation Funding, by Horizon 2020, by Projects, 2014-2022
    • Figure 18: Biotech Funding in the U.K., 2017
    • Figure 19: Active Market Players in the U.K.
    • Figure 20: Germany Health Spending, 2013-2016
    • Figure 21: Research and Development Funding in Health Research and Health Industry, 2016-2017
    • Figure 22: Chinese Pharmaceutical Sales, 2015 and 2020
    • Figure 23: List of Programs and Description
    • Figure 24: Japan's Pharmaceutical R&D Expenditure, 1995-2015
    • Figure 25: Indian's Pharmaceutical Exports, 2014-2018
    • Figure 26: Thermo Fisher Scientific, Inc.: Revenue Share, by Segment, 2017
    • Figure 27: Thermo Fisher Scientific, Inc.: Share of Revenue Generation, by Region, 2017