細胞化驗分析的全球市場和技術

全球細胞化驗分析的市場規模，2022年是292億美金。

該市場，在2022年～2027年的預測期間內預計以10.2％的年複合成長率擴大，2027年達到473億美元。

本報告提供全球細胞化驗分析市場相關調查，市場概要，以及各用途，各市場區隔，各終端用戶，各地區趨勢，COVID-19影響，及加入此市場的主要企業的簡介等資訊。

目錄

第1章 簡介

第2章 彙整和亮點

第3章 概要

第4章 藥物研發的化驗

• ADME/Tox篩檢的細胞為基礎的方法
• 市場機會
• ADME和毒性篩檢
• 多工細胞化驗分析
• 細胞化驗分析的高通量影像處理平台
• 現今的藥物研發流程的細胞化驗
• 免標定細胞化驗:藥物研發的未來
• 結論

第5章 細胞化驗分析:目前技術

第6章 細胞化驗分析的商品化

• 細胞化驗分析所扮演的角色
• 細胞化驗分析的需求
• 藥物研發和細胞化驗分析
• 市場採用的機會
• 細胞增生的檢測
• 提供細胞生長化驗的企業
• 轉移到幹細胞與免疫細胞治療
• 細胞為基礎的篩檢化驗
• 孤兒受體
• 概要

第7章 市場動態

• 細胞化驗分析的影響市場的要素
• 市場促進因素
• 市場阻礙因素

第8章 COVID-19影響

• 簡介
• 爆發
• COVID-19症狀
• COVID-19進展
• 潛伏期間
• 流行病學
• 組織和政府間的合作
• 疾病擴大
• COVID-19對細胞化驗分析市場的影響

第9章 全球細胞化驗分析市場，各用途

• 目前市場概要
• 細胞化驗分析
• 細胞化驗分析市場
• 用途
• 藥物研發
• 基礎研究
• ADME和毒物學

第10章 全球細胞化驗分析市場，各市場區隔

• 消耗品
• 設備
• 軟體
• 服務

第11章 全球細胞化驗分析市場，各終端用戶

• 生物科技企業及製藥公司
• 學術研究機關
• CRO

第12章 全球細胞化驗分析市場，各地區

• 全球市場概要
• 各地區市場
• 北美
• 歐洲
• 亞太地區
• 其他地區

第13章 競爭情形

第14章 企業簡介

• AGILENT TECHNOLOGIES INC.
• BECTON, DICKINSON & CO.
• BIOIVT
• BIO-RAD LABORATORIES
• CELL BIOLOGICS
• CELL BIOLABS INC.
• CELL SIGNALING TECHNOLOGY INC.
• CHARLES RIVER
• CORNING, INC.
• DANAHER
• DISCOVERX CORP.
• ENZO LIFE SCIENCES
• EVOTEC AG
• FUJIFILM CELLULAR DYNAMICS INC.(FCDI)
• GE HEALTHCARE
• LONZA
• MERCK KGAA
• ONCOLMMUNIN
• PERKINELMER
• PROMEGA CORP.
• THERMO FISHER SCIENTIFIC

Highlights:

The global cell-based assays market should reach $47.3 billion by 2027 from $29.2 billion in 2022 at a compound annual growth rate (CAGR) of 10.2% for the forecast period of 2022 to 2027.

The drug discovery segment of the global cell-based assays market is expected to grow from $20.9 billion in 2022 to $34.2 billion in 2027 at a CAGR of 10.3% for the forecast period of 2022 to 2027.

The basic research segment of the global cell-based assays market is expected to grow from $2.9 billion in 2022 to $4.9 billion in 2027 at a CAGR of 10.9% for the forecast period of 2022 to 2027.

Report Scope:

This report is an update of an earlier report of the same title. This report offers a comprehensive analysis of the global cell-based assays market. Segmentation is based on product, type/application and end user. Based on type/application, the market is segmented as drug discovery for validating drug targets/lead profiling assays, absorption, distribution, metabolism, and excretion (ADME) toxicity assays and basic research. The regional markets covered are North America, Europe, Asia-Pacific, and the Rest of the World (RoW).

The report provides a detailed overview and analysis of the present and future global market for cell-based assay techniques. The report analyzes in detail currently available cell-based assays and their markets. Industry growth drivers, restraints and opportunities are also discussed in detail. The report also provides information on competitive landscape, elaborative company profiles and the impact of COVID-19 on the market.

Report Includes:

• 63 tables
• An up-to-date review of the global markets for cell-based assays and related technologies
• Analyses of the global market trends, with historic sales data from 2019 to 2021, estimates for 2022, and projections of compound annual growth rates (CAGRs) through 2027
• Highlights of the current and future potential in the market for cell-based assays, and areas of focus to forecast this market into various segments and sub-segments
• Estimation of the actual market size for cell-based assays, revenue forecast, and corresponding market share analysis based on product, type/application, end user and geographic region
• Market assessment of the cell-based assays available and currently being used, new developments, spending trends, and revenue prospects for cell-based assays in the pharmaceutical industry
• Coverage of major issues involved in the research and development (R&D) of more effective cell-based approaches for drug discovery
• In-depth information on increasing investments on R&D activities, key technology issues, industry specific challenges, major types of end-user markets, and COVID-19 implications on the progress of this market
• Competitive analysis of the market for cell-based assays and updated information on the mergers, acquisitions, collaborations and recent developments during the 2020-2022 period
• Descriptive company profiles of the leading global players, including Becton, Dickinson & Company, Charles River Laboratories, General Electric Healthcare, Merck KGaA and Thermo Fisher Scientific Inc.

Table of Contents

Chapter 1 Introduction

• Study Goals and Objectives
• Reasons for Doing This Study
• What's New in This Update?
• Scope of Report
• Methodology
• Geographic Breakdown
• Analyst's Credentials
• BCC Custom Research
• Related BCC Research Reports

Chapter 2 Summary and Highlights

Chapter 3 Overview

• Introduction
• Overview: Cell-Based Assays
• Drug Discovery
• Tools for Drug Discovery
• High-Content Screening
• High-Content Screening Products
• Data Analysis
• Cell-Based Screening
• Proliferation Assays
• Apoptosis Assays
• Activation Assays
• Assays to Measure Gene Expression
• Proof of Concept for Cell-Based Assays
• Cell-Based Assays and Technology Trends
• Advancements in Cell-Based Assays
• Novel Cell-Based Assay Using Organoids, Scaffolds/Hydrogels and Organs-on-a-Chip
• Spheroids for Drug Development
• Label-Free Cell-Based Assay Technology Using Biolayer Interferometry
• Lineage Sequencing for Mutational Analysis and Cancer-Based Studies
• Evaluation of Hantavirus Replication Using In-Cell Western Assay
• Quantitative Cell-Based Assay Using a High-Content Analysis Platform
• High-Throughput Single-Cell Transcriptome Sequencing
• Ex Vivo Chemosensitivity Assays for Individualized Cancer Chemotherapy
• Luciferase-Based High-Throughput Screening Assay
• Functionally Relevant Morphological Profiling for Mesenchymal Stromal Cells
• G Protein-Coupled Receptors
• GPCRs: A Potent Class of Drug Targets
• GPCR Drugs
• Developments
• Cell-Based Assays: Screening Ion Channels

Chapter 4 Assays for Drug Discovery

• Cell-Based Approaches for ADME/Tox Screening
• Market Opportunities
• ADME and Toxicity Screening
• Multiplexed Cell-Based Assays
• High-Throughput Imaging-Based Platform for Cell-Based Assays
• Cell Assays in Today's Drug Discovery Process
• Label-Free Cellular Assays: The Relevant Future of Drug Discovery
• Conclusion

Chapter 5 Cell-Based Assays: Current Technologies

• Factors in Cell-Based Assay Development
• Reporter Gene Technology
• Cell-Based Assays for Studying Protein-Protein Interactions
• Cell-Based Protein-Fragment Complementation Assays
• Measuring Calcium Signaling
• Cell-Based Label-Free Approaches
• Label-Free Detection
• Companies
• Thermo Fisher
• CellSensor
• LanthaScreen
• Molecular Devices
• Automation and Miniaturization
• Cell Patterning
• Cell-Based Assays and Physiological Relevance
• Cell-Based Assays and Multiplexing
• Developing Reporter Assays
• Reporter Assays and Multiplexing
• Ultrahigh-Throughput Screening
• Development of the PathHunter Assay
• High-Content Screening Technology
• Imaging Cells for Cell-Based Assays
• Microscopic Visualization of Cells
• Quantum Dots
• Label-Free Imaging
• Investigational New Studies in Drug Development
• Role of ADME in Drug Design
• Prodrug Strategies
• Molecular Modeling
• Summary
• Limitations of Cell-Based Assays in the Risk Assessment Process
• Bottlenecks in Cell-Based Screening
• Methods to Improve Throughput in Cell-Based Assays
• New Technologies
• DataChip
• BIND Technology
• Miniaturization of Biological Assays
• Microfluidic Cell Culture Systems for Drug Research
• Conclusion

Chapter 6 Commercialization of Cell-Based Assays

• Role of Cell-Based Assays
• Demand for Cell-Based Assays
• Drug Discovery and Cell-Based Assays
• Opportunities for Market Adoption
• Measuring Cell Proliferation
• Companies Offering Cell Proliferation Assays
• Move toward Therapies with Stem and Immune Cells
• Cell-Based Screening Assays
• Orphan Receptors
• Summary

Chapter 7 Market Dynamics

• Factors Affecting the Market for Cell-Based Assays
• Market Drivers
• Market Restraints

Chapter 8 Impact of COVID-19

• Introduction
• Outbreak
• COVID-19 Symptoms
• Progression of COVID-19
• Incubation Period
• Epidemiology
• Collaboration between Organizations and Governments
• Spread of Disease
• Impact of COVID-19 on the Cell-Based Assay Market

Chapter 9 Global Market for Cell-Based Assays by Application

• Current Market Overview
• Cell-Based Assays
• Market for Cell-Based Assays
• Applications
• Drug Discovery
• Basic Research
• ADME and Toxicology

Chapter 10 Global Market for Cell-Based Assays by Segment

• Consumables
• Instruments
• Software
• Services

Chapter 11 Cell-Based Assays Market by End User

• Biotechnology and Pharmaceutical Companies
• Academic and Research Institutes
• Contract Research Organizations

Chapter 12 Global Market for Cell-Based Assays by Region

• Global Market Overview
• Regional Markets
• North America
• Europe
• Asia-Pacific
• Rest of the World (RoW)

Chapter 13 Competitive Landscape

• Mergers, Acquisitions, and Collaborations
• Recent Developments
• Competitive Analysis

Chapter 14 Company Profiles

• AGILENT TECHNOLOGIES INC.
• BECTON, DICKINSON & CO.
• BIOIVT
• BIO-RAD LABORATORIES
• CELL BIOLOGICS
• CELL BIOLABS INC.
• CELL SIGNALING TECHNOLOGY INC.
• CHARLES RIVER
• CORNING, INC.
• DANAHER
• DISCOVERX CORP.
• ENZO LIFE SCIENCES
• EVOTEC AG
• FUJIFILM CELLULAR DYNAMICS INC. (FCDI)
• GE HEALTHCARE
• LONZA
• MERCK KGAA
• ONCOLMMUNIN
• PERKINELMER
• PROMEGA CORP.
• THERMO FISHER SCIENTIFIC

List of Tables

• Summary Table A : Global Market for Cell-Based Assays, Through 2027
• Summary Table B : Global Market for Cell-Based Assays, by Application, Through 2027
• Table 1 : Uses of Cell-Based Assays by Area
• Table 2 : Types of Cell-based Assays
• Table 3 : Apoptotic Markers
• Table 4 : Proof of Concept for Cell-Based Assays
• Table 5 : Materials and Manufacturers of Hydrogels, by Type
• Table 6 : Minimum Requirements for Organ-on-a-Chip Units, by Type
• Table 7 : HCS Instrumentation Available in the Market, by Company
• Table 8 : HCS Informatics Tools Available in the Market, by Application
• Table 9 : Selected High-Throughput Instruments Available in the Market
• Table 10 : Assay Methods Used to Study GPCRs
• Table 11 : GPCR Primary Screening Assays
• Table 12 : Key GPCR Targeting Drugs
• Table 13 : Key Companies with GPCR Products
• Table 14 : Omeros' GPCRs and Their Indications
• Table 15 : Biological Assay Systems for the Evaluation of Cytochrome P450 Enzyme Isoforms
• Table 16 : Types of Hepatocyte Assay Systems
• Table 17 : Types of ADME Assays
• Table 18 : Common Types of Toxicity Assays
• Table 19 : Traditional Methods of ADME/Tox Testing
• Table 20 : Conventional In Vitro ADME/Tox Screening Methods
• Table 21 : Applications of Label-Free Assays
• Table 22 : Factors for Cell-Based Assay Development
• Table 23 : Approaches to Cell-Based Systems for Drug Screening
• Table 24 : Thermo Fisher's Products
• Table 25 : Thermo Fisher's Cell-Based Technologies
• Table 26 : List of Current Confocal HCS Platforms
• Table 27 : Widefield HCS Platforms, by Type
• Table 28 : List of Studies for Filing an Investigational New Drug Application
• Table 29 : List of Studies for Clinical Filings
• Table 30 : List of Existing Cell-Based Assay Technologies
• Table 31 : Limitations of Cell-Based Assays
• Table 32 : Biological Applications for High-Content Analysis
• Table 33 : Total Number of New Cases and Deaths Due to Various Cancers Globally, 2020
• Table 34 : U.S. NIH Funding for Various Disease Conditions, 2014-2020
• Table 35 : COVID-19 Clinical Symptom Distribution
• Table 36 : COVID-19 Confirmed Cases and Deaths, by WHO Region, June 15, 2022
• Table 37 : Global Market for Cell-Based Assays, Through 2027
• Table 38 : Global Market for Cell-Based Assays, by Application, Through 2027
• Table 39 : Global Market for Cell-Based Assays in Drug Discovery, by Region, Through 2027
• Table 40 : Global Market for Cell-Based Assays for Basic Research, by Region, Through 2027
• Table 41 : Global Market for Cell-Based Assays in ADME and Toxicology, by Region, Through 2027
• Table 42 : Global Market for Cell-Based Assays, by Segment, Through 2027
• Table 43 : Global Market for Consumables, by Region, Through 2027
• Table 44 : Global Market for Instruments, by Region, Through 2027
• Table 45 : Global Market for Software, by Region, Through 2027
• Table 46 : Global Market for Services, by Region, Through 2027
• Table 47 : Global Market for Cell-Based Assays, by End User, Through 2027
• Table 48 : Global Market for Cell-Based Assays Used by Pharmaceutical and Biotechnology Companies, by Region, Through 2027
• Table 49 : Global Market for Cell-Based Assays Used by Academic and Research Institutes, by Region, Through 2027
• Table 50 : Global Market for Cell-Based Assays Used by Contract Research Organizations, by Region, Through 2027
• Table 51 : Growth Drivers of the Cell-Based Assay Market
• Table 52 : Global Market for Cell-Based Assays, by Region, Through 2027
• Table 53 : North American Market for Cell-Based Assays, by Country, Through 2027
• Table 54 : European Market for Cell-Based Assays, by Country, Through 2027
• Table 55 : Asia-Pacific Market for Cell-Based Assays, by Country, Through 2027
• Table 56 : Mergers, Acquisitions and Collaborations, 2019-2022
• Table 57 : Competitive Analysis of the Market for Cell-Based Assays, 2021
• Table 58 : Becton, Dickinson & Company: Business Segment
• Table 59 : Charles River Laboratories: Business Segments
• Table 60 : Danaher: Business Segment
• Table 61 : Thermo Fisher Scientific Inc.: Business Segments

List of Figures

• Summary Figure A : Global Market for Cell-Based Assays, 2019-2027
• Summary Figure B : Global Market for Cell-Based Assays, by Application, 2019-2027
• Figure 1 : Projected Global Aging Population (65 Years and Above), 1990-2050
• Figure 2 : Drug Discovery Process Steps
• Figure 3 : Process Flow for Patient-Derived Organoid Cell Assay
• Figure 4 : Basic Architecture of Organ-on-a-Chip Systems
• Figure 5 : Cell Viability and Kinase Assays Used to Measure Change in ATP Levels
• Figure 6 : Distribution of Top 20 Diseases for Mesenchymal Stromal Cell-Related Clinical Studies, 2021
• Figure 7 : Distribution of Approved Drugs with Unique GPCRs, 2019
• Figure 8 : Personalized Medicines on the Market, 2008-2020
• Figure 9 : Global Pharmaceutical R&D Spending, 2010-2019
• Figure 10 : Global Market for Cell-Based Assays, by Application, 2019-2027
• Figure 11 : Global Market Shares of Cell-Based Assays, by Application, 2021
• Figure 12 : Global Market for Cell-Based Assays in Drug Discovery, by Region, 2019-2027
• Figure 13 : Global Market for Cell-Based Assays for Basic Research, by Region, 2019-2027
• Figure 14 : Phase Transition Success Rates and Likelihood of Approval from Phase I for All Diseases, All Modalities, 2011-2020
• Figure 15 : Global Market for Cell-Based Assays in ADME and Toxicology, by Region, 2019-2027
• Figure 16 : Global Market for Cell-Based Assays, by Segment, 2019-2027
• Figure 17 : Global Market Shares of Cell-Based Assays, by Segment, 2021
• Figure 18 : Global Market for Consumables, by Region, 2019-2027
• Figure 19 : Global Market for Instruments, by Region, 2019-2027
• Figure 20 : Global Market for Software, by Region, 2019-2027
• Figure 21 : Global Market for Services, by Region, 2019-2027
• Figure 22 : Global Market for Cell-Based Assays, by End User, 2019-2027
• Figure 23 : Global Market Shares of Cell-Based Assays, by End User, 2021
• Figure 24 : Biopharmaceuticals R&D Spending, 2010-2024
• Figure 25 : Global Market for Cell-Based Assays Used by Pharmaceutical and Biotechnology Companies, by Region, 2019-2027
• Figure 26 : Global Market for Cell-Based Assays for Academic and Research Institutes, by Region, 2019-2027
• Figure 27 : Global Market for Cell-Based Assays Used by Contract Research Organizations, by Region, 2019-2027
• Figure 28 : Global Market for Cell-Based Assays, by Region, 2019-2027
• Figure 29 : Global Market Shares of Cell-Based Assays, by Region, 2021
• Figure 30 : North American Market for Cell-Based Assays, by Country 2019-2027
• Figure 31 : U.S. Market for Cell-Based Assays, 2019-2027
• Figure 32 : Canadian Market for Cell-Based Assays, 2019-2027
• Figure 33 : European Market for Cell-Based Assays, by Country, 2020-2027
• Figure 34 : U.K. Market for Cell-Based Assays, 2019-2027
• Figure 35 : German Market for Cell-Based Assays, 2019-2027
• Figure 36 : French Market for Cell-Based Assays, 2019-2027
• Figure 37 : Italian Market for Cell-Based Assays, 2019-2027
• Figure 38 : Spanish Market for Cell-Based Assays, 2019-2027
• Figure 39 : Rest of the European Market for Cell-Based Assays, 2019-2027
• Figure 40 : Asia-Pacific Market for Cell-Based Assays, by Country, 2020-2027
• Figure 41 : Chinese Market for Cell-Based Assays, 2019-2027
• Figure 42 : Japanese Market for Cell-Based Assays, 2019-2027
• Figure 43 : Indian Market for Cell-Based Assays, 2019-2027
• Figure 44 : Rest of Asia-Pacific Market for Cell-Based Assays, 2019-2027
• Figure 45 : Rest of the World Market for Cell-Based Assays, 2019-2027
• Figure 46 : Becton, Dickinson & Company: Annual Revenue, 2019-2021
• Figure 47 : Becton, Dickinson & Company: Market Shares, by Region, 2021
• Figure 48 : Becton, Dickinson & Company: Market Shares, by Business Segment, 2021
• Figure 49 : Charles River Laboratories: Annual Revenue, 2019-2021
• Figure 50 : Charles River Laboratories: Market Share, by Region, 2021
• Figure 51 : Charles River Laboratories: Market Share, by Segment, 2021
• Figure 52 : Danaher: Annual Revenue, 2019-2021
• Figure 53 : Danaher: Diagnostic Segment Market Shares, by Region, 2021
• Figure 54 : Danaher: Market Shares, by Business Segment, 2021
• Figure 55 : Eurofins Pharma Discovery Services (Eurofins DiscoverX Products): Annual Revenue, 2019-2021
• Figure 56 : Eurofins DiscoverX Products: Market Share, by Region, 2021
• Figure 57 : General Electric Healthcare: Annual Revenue, 2019-2021
• Figure 58 : General Electric Healthcare: Market Shares, by Region/Country, 2021
• Figure 59 : General Electric Healthcare: Market Shares, by Business Segment, 2021
• Figure 60 : Lonza: Annual Revenue, 2020 and 2021
• Figure 61 : Lonza: Market Shares, by Business Segment, 2021
• Figure 62 : Merck KGaA: Annual Revenue, 2019-2021
• Figure 63 : Merck KGaA: Market Share, by Region, 2021
• Figure 64 : Merck KGaA: Market Share, by Segment, 2021
• Figure 65 : PerkinElmer: Annual Revenue, 2019-2021
• Figure 66 : PerkinElmer: Market Share, by Region/Country, 2021
• Figure 67 : PerkinElmer: Market Shares, by Business Unit, 2021
• Figure 68 : Thermo Fisher Scientific Inc.: Annual Revenue, 2019-2021
• Figure 69 : Thermo Fisher Scientific Inc.: Market Shares, by Region, 2021
• Figure 70 : Thermo Fisher Scientific Inc.: Market Shares, by Business Segment, 2021