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英文調查報告書

生物醫藥品企業製藥階段的合作契約

Discovery Stage Partnering Agreements in Biopharma

出版商 CurrentPartnering, a division of Wildwood Ventures Limited 聯絡我們
出版日期 2008/09 內容資訊 363 pages
商品編碼 72138
價格 US $ 2,395 ~ Price List
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Abstract

Summary

The Discovery Stage Partnering Agreements in Biopharma report provides comprehensive understanding and unprecedented access to the discovery stage partnering agreements entered into by the worlds leading biopharma companies.

  • Discovery stage payment terms
  • Discovery stage partnering contract documents
  • Discovery stage partnering agreement terms
  • Discovery stage partnering agreement structure
  • Top discovery deals by value
  • Most active discovery stage dealmakers
  • plus much more

Description

The Discovery Stage Partnering Agreements in Biopharma report detailed understanding and analysis of how and why companies enter discovery stage licensing/business development and other forms of partnering arrangement.

The report provides a detailed understanding and analysis of how and why companies enter discovery stage licensing/business development and other forms of partnering arrangement.

The focus of the report is on partnerships for discovery technologies and discovery stage compounds where partners have joined forces to exploit these early stage opportunities. This is the earliest stage of partnering undertaken by commercial entities with the objective of utilizing discovery technologies to identify promising drug candidates.

The report provides access to average discovery stage deal payment terms as announced between the parties. This data provides useful insight into the average and range of payments for upfront, milestone and royalty payments agreed for discovery stage deals.

This report contains over 1000 links to online copies of actual discovery stage contract documents as submitted to the Securities Exchange Commission by biopharma companies and their partners.

The initial chapters of this report provide an orientation of discovery stage dealmaking and business activities. Chapter 1 provides an introduction to the report, whilst chapter 2 provides an analysis of the trends in discovery stage partnering as well as a discussion on the merits and attributes of dealmaking at the discovery stage of development.

Chapter 3 provides an overview of the structure of discovery stage partnering deal contracts. The chapter includes numerous case studies to enable understanding of discovery stage partnering deals.

Chapter 4 provides a review of the leading discovery stage partnering deals since 2000. Deals are listed by headline value, signed by bigpharma, most active bigpharma, and most active of all biopharma companies. Where the deal has an agreement contract published at the SEC a link provides online access to the contract.

Chapter 5 provides a comprehensive listing of the top 50 bigpharma companies with a brief summary followed by a comprehensive listing of discovery stage contract documents available in the public domain. Each deal title links via Weblink to an online version of the actual contract document, providing easy access to each contract document on demand.

Chapter 6 provides a comprehensive listing of all discovery stage agreement contracts since 2003 available in the public domain, respectively. Each chapter is organized by A-Z, therapeutic area, and deal type. Each deal title links via Weblink to an online version of the actual contract document, providing easy access to each contract document on demand.

The report also includes numerous tables and figures that illustrate the trends and activities in discovery stage dealmaking since 2000.

In conclusion, this report provides everything a prospective dealmaker needs to know about discovery stage partnering, enabling thorough learning, education and due diligence prior and during the discovery stage dealmaking process.

Table of Contents

Executive Summary

Chapter 1 - Introduction

Chapter 2 - Trends in discovery stage dealmaking

  • 2.1. Introduction
  • 2.2. Difference between discovery technologies and discovery compound deals
    • 2.2.1. Trends in discovery stage deals since 2000
    • 2.2.2. Attributes of discovery stage deals
  • 2.3. Reasons for entering into discovery stage partnering deals
    • 2.3.1. Licensors reasons for entering discovery stage deals
    • 2.3.2. Licensees reasons for entering discovery stage deals
  • 2.4. Components of discovery stage deals
  • 2.5. Therapeutic focus of discovery stage deals
    • 2.5.1. Oncology discovery dealmaking
    • 2.5.2. CNS discovery dealmaking
    • 2.5.3. Infectious discovery dealmaking
    • 2.5.4. Autoimmune/Inflammatory discovery dealmaking
  • 2.6. Technology focus of discovery deals
  • 2.7. The future of discovery stage partnering deals

Chapter 3 - Overview of discovery stage deal structure

  • 3.1. Introduction
  • 3.2. The anatomy of a discovery stage deal
    • 3.2.1. Example discovery stage agreements
      • 3.2.1.a. Case study 1: Celgene - Array Biopharma - September 2007
      • 3.2.1.b. Case study 2: GlaxoSmithKline - Targacept - July 2007
  • 3.3. Typical discovery stage payment terms
    • 3.3.1. Headline deal values
    • 3.3.2. Upfront payments
    • 3.3.3. Milestone payments
    • 3.3.4. Royalties

Chapter 4 - Leading discovery stage deals

  • 4.1. Introduction
  • 4.2. Top discovery stage deals by value
  • 4.3. Top discovery stage deals signed by bigpharma
  • 4.4. Most active discovery stage dealmakers
  • 4.5. Bigpharma discovery stage deal activity

Chapter 5 - Bigpharma discovery stage partnering agreements

  • 7.1. Introduction
  • 7.2. How to use discovery stage partnering agreements
  • 7.3. Company discovery stage partnering agreement listings
  • Abbott
  • Actavis
  • Alcon Labs
  • Allergan
  • Amgen
  • Astellas
  • AstraZeneca
  • Barr Pharmaceuticals
  • Baxter International
  • Bayer
  • Biogen Idec
  • Boehringer Ingelheim
  • Bristol-Myers Squibb
  • Chugai
  • CSL
  • Daiichi Sankyo
  • Eisai
  • Eli Lilly
  • Forest Laboratories
  • Genentech
  • Genzyme
  • Gilead Sciences
  • GlaxoSmithKline
  • Johnson & Johnson
  • King
  • Lundbeck
  • Menarini
  • Merck & Co
  • Merck - Serono KGaA
  • Mitsubishi
  • Mundipharma
  • Novartis AG
  • Novo Nordisk
  • Nycomed Pharma
  • Otsuka
  • Pfizer
  • Procter & Gamble
  • Ratiopharm
  • Roche
  • Sanofi-Aventis
  • Schering Plough
  • Servier
  • Shire
  • Solvay
  • Stada
  • Takeda
  • Teva
  • UCB
  • Watson
  • Wyeth

Chapter 6 - Discovery partnering agreement directory 2003-early 2008

  • 6.1. Introduction
  • 6.2. Company A-Z
  • 6.3. By therapy area
  • Accident/Hospital/Trauma
  • Blood/Lymphatic System
  • Cardiovascular
  • Central nervous System
  • Dermatology
  • Gastrointestinal
  • Genetic
  • Genitourinary
  • Autoimmune/Inflammatory
  • Infection
  • Metabolism
  • Musculoskeletal
  • Oncology
  • Respiratory
  • Sensory Organ / Oral Health
  • Delivery
  • 6.4. By deal type
  • Collaborative R&D
  • Co-development
  • Co-marketing
  • Co-promotion
  • Development
  • Distribution
  • Joint venture
  • Licensing
  • M&A
  • Manufacturing
  • Marketing
  • Promotion
  • Research
  • Supply

Appendices

  • Appendix 1 - Discovery stage partnering references
  • Appendix 2 - Resources
  • Appendix 3 - Deal type definitions
  • Appendix 3 - Deal type definitions
  • Appendix 4 - Example discovery stage partnering contract
  • About CurrentPartnering
  • Recent report titles from CurrentPartnering
  • Order Form - Reports
  • Order form - Company Dealmaking Profiles

Table of figures

  • Figure 1: Definition of discovery technology and discovery compound dealmaking
  • Figure 2: Trends in discovery stage deal announcements, 2000-2007
  • Figure 3: Frequency of deal components in discovery stage deals - 2003 to mid2008
  • Figure 4: Discovery stage deals by therapy focus - 2003 - mid2008
  • Figure 5: Frequency of oncology discovery dealmaking 2003-mid2008
  • Figure 6: Primary discovery stage oncology dealmakers
  • Figure 7: Frequency of CNS discovery dealmaking 2003-mid2008
  • Figure 8: Primary discovery stage CNS dealmakers
  • Figure 9: Frequency of infectious discovery dealmaking 2003-mid2008
  • Figure 10: Primary discovery stage infectious dealmakers
  • Figure 11: Frequency of autoimmune/inflammatory discovery dealmaking 2003-mid2008
  • Figure 12: Primary discovery stage autoimmune/inflammatory dealmakers
  • Figure 13: Technology focus for discovery deals 2003-mid2008
  • Figure 14: Components of the discovery deal structure
  • Figure 15: Discovery stage average payment terms
  • Figure 16: Top discovery stage deals by value since 2003
  • Figure 17: Bigpharma - top 50 - discovery stage deals since 2003
  • Figure 18: Most active discovery stage dealmakers 2003-mid 2008
  • Figure 19: Bigpharma - top 50 - discovery stage deals since 2003
  • Figure 20: Online partnering resources
  • Figure 21: Deal type definitions
  • Figure 22: Partnering agreement between Dart Therapeutics and CombinatoRx - November 2007
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