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市場調查報告書

未來的凝固檢查市場:成長機會和事業擴張策略

Future Coagulation Testing Market: Growth Opportunities and Business Expansion Strategies

出版商 Venture Planning Group
出版日期 2011年12月 商品編碼 223934
內容資訊 英文  
價格
US $ 28700 PDF by E-mail (Local license)
US $ 63100 PDF by E-mail (Global license)


未來的凝固檢查市場:成長機會和事業擴張策略 是由出版商Venture Planning Group在2011年12月所出版的。 這份英文市場調查報告書價格從美金28700起跳。

簡介

本報告書內容包括:全球的凝固檢查市場的現況和展望的調查分析、主要凝固檢查的技術和概要、主要測定機器的展望、主要對外診斷技術和其他用途、全球及主要國家市場的事業環境、市場結構、市場規模及成長率、主要供應商、加入企業的成長機會和事業擴張策略的彙整、內容綱要摘記如下:

介紹

全球市場・技術概要

  • 主要常規凝固檢查・ 特殊凝固檢查
    • 活性化部分凝血活酶時間(APTT)
    • α2抗纖維蛋白溶酶
    • 抗凝血酵素III
    • 出血時間
    • D二聚體
    • 酒精凝集(凝膠作用)檢查
    • 優球蛋白溶解
    • 因子免疫
    • 纖維分解產物
    • 纖維
    • 肝素
    • 水蛭素
    • 高凝血狀態・血栓
    • 脂肪蛋白(a)
    • 纖維蛋白分解酵素
    • 纖維蛋白原
    • 纖維蛋白原活性化因子抑制劑(PAI)
    • 血小板機能檢查
    • 血小板凝集
    • 蛋白質C・蛋白質S
    • 凝血酵素碎片1+2
    • 凝血酵素原時間(PT)
    • 蛇毒素試驗時間
    • 凝血時間
    • 組織纖維蛋白原活性化因子(t-PA)
    • Von Willebrand's因子
  • 測定機器的展望
  • 主要體外診斷(體外診斷)技術和其用途
    • 色原性基質
    • 單株抗體・多株抗體
    • 免疫
    • 微電腦
    • 自動化
    • DNA核酸探針
    • 人工智慧
    • 乾式化學
    • 生物感應器
  • 全球市場的概要
    • 商業環境
    • 市場構造
    • 市場規模・市場成長率
    • POC檢查市場

法國

德國

義大利

日本

西班牙

英國

美國

主要產品開發的機會

分散型檢查產品的設計基準

替代的市場加入策略

市場加入的潛在性障礙和風險

競爭分析

圖表

目錄

Abstract

Description

The growing cost-containment pressures in major industrialized nations, coupled with continued technological advances in chromagenic substrates, monoclonal antibodies, immunoassays, molecular diagnostics, computers and laboratory automation will radically change the coagulation testing practice during the next ten years. New specific and sensitive markers of hemostasis will be increasingly used on automated instrumentation. Coagulation testing will also become more standardized, offering opportunities for quality control products and services. Moreover, the continuing contraction of the hospital system and technological advances will facilitate decentralization of the coagulation testing closer to the patient, thus creating additional opportunities and challenges for suppliers.

This comprehensive worldwide study is designed to help current suppliers and potential market entrants identify and evaluate major business opportunities emerging in the coagulation market during the next decade. The study explores business and technological trends in major markets; provides estimates of the test volume, instrument placements and installed base; as well as sales and market shares of leading competitors; compares features of major analyzers; profiles leading market players; and identifies specific product and business opportunities facing instrument and consumable suppliers during the next ten years.

Contains 650 pages and 150 tables

Table of Contents

Introduction

Worldwide Market and Technology Overview

A. Major Routine and Special Coagulation Tests

  • 1. Introduction
  • 2. Activated Partial Thromboplastin Time (APTT)
  • 3. Alpha-2 Antiplasmin
  • 4. Antithrombin III
  • 5. Bleeding Time
  • 6. D-Dimer
  • 7. Ethanol Flocculation Test
  • 8. Euglobulin Lysis
  • 9. Factor Assays
    • a. Introduction
    • b. Factor II
    • c. Factor V/Factor V Leiden
    • d. Factor VII
    • e. Factor VIII
    • f. Factor IX
    • g. Factor IXa
    • h. Factor X (Stuart Factor)
    • i. Factor Xa
    • j. Factor XI
    • k. Factor XII
    • l. Factor XIII
  • 10. Fibrin Degradation Products
  • 11. Fibrinogen
  • 12. Heparin
  • 13. Hirudin
  • 14. Hypercoagulability and Thrombosis
  • 15. Lipoprotein a
  • 16. Plasmin
  • 17. Plasminogen
  • 18. Plasminogen Activator Inhibitor (PAI)
  • 19. Platelet Function Tests
  • 20. Platelet Aggregation
  • 21. Proteins C and S
  • 22. Prothrombin Fragment 1.2
  • 23. Prothrombin Time (PT)
  • 24. Reptilase Time
  • 25. Thrombin Time
  • 26. Tissue-Type Plasminogen Activator (t-PA)
  • 27. Von Willebrand's Factor

B. Instrumentation Review

  • Introduction
  • Benk Hemolab
  • Benk TRT Thrombotimer
  • Bio/Data MCA 310
  • Bio/Data MCA 210
  • Bio/Data PAP-4C D/4D/4C
  • Cardiovascular Diagnostics COAG
  • Diagnostica Stago STA Compact
  • Diagnostica Stago STA-R
  • Diagnostica Stago Star 4/8
  • Helena Laboratories Cascade 480
  • Helena Laboratories Cascade M
  • Helena Laboratories PACKS-4
  • Helena THOR
  • Instrumentation Laboratory ACL 100 and 1000 series
  • Instrumentation Laboratory ACL6000
  • Instrumentation Laboratory ACL7000
  • Instrumentation Laboratory ACL9000
  • Instrumentation Laboratory Electra 1000C
  • Instrumentation Laboratory Electra 1400C
  • Instrumentation Laboratory Electra 1600/C
  • Instrumentation Laboratory Electra 1800C
  • Instrumentation Laboratory Futura
  • ITC Hemochron 8000
  • Roche Diagnostics CoaguChek
  • Siemens BCS
  • Siemens BCT
  • Siemens BF II/Fibrintimer Series
  • Sysmex CA-50
  • Sysmex CA-500
  • Sysmex CA-1500
  • Sysmex CA-5000/CA-1000
  • Sysmex CA-6000
  • Sysmex CA-7000
  • Teco Coatron II/Jr./AccuStasis 5000
  • Trinity Biotech Amax CS190
  • Trinity Biotech Amax CS400
  • Trinity Biotech Coag-A-Mate Max
  • Trinity Biotech KC 40, 4A, 1A Series
  • Trinity Biotech MDA 180
  • Trinity Biotech Coag-A-Mate MTX
  • Trinity Biotech Coag-A-Mate RA4
  • Trinity Biotech Coag-A-Mate XC/Plus
  • Trinity Biotech Coag-A-Mate XM

C. Major in Vitro Diagnostic Technologies and Their Potential Applications

  • 1. Chromogenic Substrates
  • 2. Monoclonal and Polyclonal Antibodies
  • 3. Immunoassays
    • a. Applications
    • b. Technological Principle
    • c. Enzyme Immunoassays (EIA)
      • Overview
      • ELISA
      • EMIT
      • Dot Immunobinding Assays
      • Capillary Immunoassays
      • Enzyme Amplification
      • Electrochemical Immunoassay
    • d. Fluorescent Immunoassays
      • Fluorescence Polarization
      • Time-Resolved Pulse Fluorescence
      • Fluorescence Lifetime
    • e. Latex Agglutination
    • f. Immunoprecipitation
    • 4. Microcomputers
  • 5. Automation
  • 6. Robotics
  • 7. DNA Probes
    • a. Overview
    • b. Amplification Methods
      • PCR
      • Ligase Chain Reaction
      • Branched DNA
      • Q-Beta Replicase
      • NASBA
      • SDA
      • 3 SR
      • HPA
      • Two-Tiered System
      • LAT
  • 8. Artificial Intelligence
  • 9. Dry Chemistry
  • 10. Biosensors

D. Worldwide Market Overview

  • 1. Business Environment
  • 2. Market Structure
  • 3. Market Size and Growth
  • 4. POC Testing Market

France

  • A. Executive Summary
  • B. Business Environment
  • C. Market Structure
  • D. Market Size, Growth and Major Suppliers

Germany

  • A. Executive Summary
  • B. Business Environment
  • C. Market Structure
  • D. Market Size, Growth and Major Suppliers

Italy

  • A. Executive Summary
  • B. Business Environment
  • C. Market Structure
  • D. Market Size, Growth and Major Suppliers

Japan

  • A. Executive Summary
  • B. Business Environment
  • C. Market Structure
  • D. Market Size, Growth and Major Suppliers

Spain

  • A. Executive Summary
  • B. Business Environment
  • C. Market Structure
  • D. Market Size, Growth and Major Suppliers

UK

  • A. Executive Summary
  • B. Business Environment
  • C. Market Structure
  • D. Market Size, Growth and Major Suppliers

USA

  • A. Executive Summary
  • B. Business Environment
    • 1. Health Care Expenditures
    • 2. Cost Consciousness
    • 3. Industry Consolidation
    • 4. Managed Care
    • 5. Hospitals
    • 6. Admissions
    • 7. Length of Stay
    • 8. Industry Diversification
    • 9. Physician Demographics
    • 10. Population Aging
      • a. Chronic Illnesses
      • b. Disease Incidence
      • c. Susceptibility to Iatrogenesis
      • d. Multiple Illness Cases
    • 11. Laboratory Regulations
  • C. Market Structure
  • 1. Centralized Testing
    • a. Hospitals
    • b. Commercial laboratories
  • 2. Decentralized Testing
    • a. Physician Offices/Group Practices
    • b. Point-of-Care Testing
    • c. Home/Self Testing
    • d. Other Decentralized Testing Locations
  • D. Market Size, Growth And Major Suppliers

Major Product Development Opportunities

Design Criteria For Decentralized Testing Products

Alternative Market Penetration Strategies

A. Internal Development B. Collaborative Arrangements C. University Contracts D. Distribution Strategies for Decentralized Testing Markets 1. Marketing Approaches 2. Product Complexity 3. Customer Preference 4. Established Suppliers 5. Emerging Suppliers 6. Major Types Of Distributors 7. Market Segmentation

Potential Market Entry Barriers and Risks

A. Market Maturity B. Cost Containment C. Competition D. Technological Edge and Limitations E. Patent Protection F. Regulatory Constraints G. Decentralized Testing Market Challenges

Competitive Assessments

Abbott American Diagnostica Avocet Medical Axis-Shield Beckman Coulter Becton Dickinson Bio/Data Corporation Biosite Chrono-Log Corgenix Medical Diagnostica Stago Helena Laboratories HYPEN BioMed Instrumentation Laboratory ITC Nanogen Roche Siemens Sienco Sysmex Thermo Fischer Trinity Biotech ZyCare

List of Tables

  • Major Companies Developing or Marketing Activated Clotting Time Tests
  • Major Companies Developing or Marketing APTT Tests
  • Major Companies Developing or Marketing Alpha-2 Antiplasmin Tests
  • Major Companies Developing or Marketing Antithrombin III Tests
  • Major Companies Developing or Marketing Bleeding Time Tests
  • Major Companies Developing or Marketing D-dimer Tests
  • Major Companies Developing or Marketing Factor Assays
  • Major Companies Developing or Marketing Fibrin Degradation Product Tests
  • Major Companies Developing or Marketing Fibrinogen Tests
  • Major Companies Developing or Marketing Heparin Tests
  • Major Companies Developing or Marketing Plasmin Tests
  • Major Companies Developing or Marketing Plasminogen Tests
  • Major Companies Developing or Marketing Plasminogen Activator Inhibitor Tests
  • Major Companies Developing or Marketing Platelet Aggregation Tests
  • Major Companies Developing or Marketing Protein C Tests
  • Major Companies Developing or Marketing Protein S Tests
  • Major Companies Developing or Marketing PT Tests
  • Major Companies Developing or Marketing Thrombin Time Tests
  • Major Companies Developing or Marketing TPA Tests
  • Major Companies Developing or Marketing Von Willebrand's Factor Tests
  • Worldwide, All Market Segments, Laboratories Performing Coagulation Tests By Country, 2010
  • Worldwide, All Market Segments, Total Coagulation Test Volume By Country, 2010-2020
  • Worldwide, All Market Segments, Total Coagulation Reagent Market By Country, 2010-2020
  • Worldwide, All Market Segments, Total Coagulation Instrument Market By Country, 2010-2020
  • Worldwide, All Market Segments, Total Coagulation Diagnostics Market By Country, 2010-2020
  • Executive Summary Table: France, Total Coagulation Diagnostics Market By Market Segment and Product Category, 2010-2020
  • France, Laboratories Performing Coagulation Tests By Market Segment, 2010
  • France, Hospital Laboratories Performing Coagulation Tests By Bed Size, 2010
  • France, Commercial/Private Laboratories Performing Coagulation Tests By Annual Test Volume, 2010
  • France, Hospital Laboratories Average Daily Test Volume, 2010
  • France, Commercial/Private Laboratories Average Daily Test Volume, 2010
  • France, Total Coagulation Test Volume By Market Segment, 2010-2020
  • France, All Market Segments Coagulation Test Volume, 2010-2020
  • France, Hospital Laboratories Coagulation Test Volume, 2010-2020
  • France, Commercial/Private Laboratories Coagulation Test Volume, 2010-2020
  • France, Coagulation Reagent Market By Market Segment, 2010-2020
  • France, Major Suppliers of Coagulation Reagents Estimated Sales and Market Shares, 2010
  • France, Coagulation Instrument Market By Market Segment, 2010-2020
  • France, Major Suppliers of Coagulation Analyzers, Estimated Total Instrument Placements and Market Shares, 2010
  • France, Major Suppliers of Coagulation Analyzers, Estimated Placements and Installed Base By Supplier and Model, 2010
  • France, Major Suppliers of Coagulation Analyzers, Estimated Instrument Sales and Market Shares, 2010
  • France, Total Coagulation Diagnostics Market By Product Category, 2010-2020
  • France, Major Suppliers of Coagulation Diagnostic Products, Estimated Sales and Market Shares, 2010
  • Executive Summary Table: Germany, Total Coagulation Diagnostics Market By Market Segment and Product Category, 2010-2020
  • Germany, Laboratories Performing Coagulation Tests By Market Segment, 2010
  • Germany, Hospital Laboratories Performing Coagulation Tests By Bed Size, 2010
  • Germany, Commercial/Private Laboratories Performing Coagulation Tests By Annual Test Volume, 2010
  • Germany, Hospital Laboratories Average Daily Test Volume, 2010 Germany, Commercial/Private Laboratories Average Daily Test Volume, 2010
  • Germany, Physician Offices/Group Practice Average Daily Test Volume, 2010
  • Germany, Total Coagulation Test Volume By Market Segment, 2010-2020
  • Germany, All Market Segments Coagulation Test Volume, 2010-2020
  • Germany, Hospital Laboratories Coagulation Test Volume,2010-2020
  • Germany, Commercial/Private Laboratories Coagulation Te st Volume, 2010-2020
  • Germany, Physician Offices/Group Practices Coagulation Test Volume, 2010-2020
  • Germany, Coagulation Reagent Market By Market Segment, 2010-2020
  • Germany, Major Suppliers of Coagulation Reagents, Estimated Sales and Market Shares, 2010
  • Germany, Coagulation Instrument Market By Market Segment, 2010-2020
  • Germany, Major Suppliers of Coagulation Analyzers, Estimated Total Instrument Placements and Market Shares, 2010
  • Germany, Major Suppliers of Coagulation Analyzers, Estimated Placements and Installed Base By Supplier and Model, 2010
  • Germany, Major Suppliers of Coagulation Analyzers, Estimated Instrument Sales and Market Shares, 2010
  • Germany, Total Coagulation Diagnostics Market By Product Category, 2010-2020
  • Germany, Major Suppliers of Coagulation Diagnostic Products, Estimated Sales and Market Shares, 2010
  • Executive Summary Table: Italy, Total Coagulation Diagnostics Market By Market Segment and Product Category, 2010-2020
  • Italy, Laboratories Performing Coagulation Tests By Market Segment, 2010
  • Italy, Hospital Laboratories Performing Coagulation Tests By Bed Size, 2010
  • Italy, Commercial/Private Laboratories Performing Coagulation Tests By Annual Test Volume, 2010
  • Italy, Hospital Laboratories Average Daily Test Volume, 2010 Italy, Commercial/Private Laboratories Average Daily Test Volume, 2010
  • Italy, Total Coagulation Test Volum By Market Segment, 2010-2020
  • Italy, All Market Segments Coagulation Test Volume, 2010-2020
  • Italy, Hospital Laboratories Coagulation Test Volume, 2010-2020
  • Italy, Commercial/Private Laboratories Coagulation Test Volume, 2010-2020
  • Italy, Coagulation Reagent Market By Market Segment, 2010-2020
  • Italy, Major Suppliers of Coagulation Reagents Estimated Sales and Market Shares, 2010
  • Italy, Coagulation Instrument Market By Market Segment, 2010-2020
  • Italy, Major Suppliers of Coagulation Analyzers, Estimated Total Instrument Placements and Market Shares, 2010
  • Italy, Major Suppliers of Coagulation Analyzers, Estimated Placements and Installed Base By Supplier and Model, 2010
  • Italy, Major Suppliers of Coagulation Analyzers, EstimatedInstrument Sales and Market Shares, 2010
  • Italy, Total Coagulation Diagnostics Market By Product Cat egory,2010-2020
  • Italy, Major Suppliers of Coagulation Diagnostic Products, Estimated Sales and Market Shares, 2010
  • Executive Summary Table: Japan, Total Coagulation Diagnostics Market By Market Segment and Product Category, 2010-2020
  • Japan, Laboratories Performing Coagulation Tests By Market Segment, 2010
  • Japan, Hospital Laboratories Performing Coagulation Tests By Bed Size, 2010
  • Japan, Commercial/Private Laboratories Performing Coagulation Tests By Annual Test Volume, 2010
  • Japan, Hospital Laboratories Average Daily Test Volume, 2010 Japan, Commercial/Private Laboratories Average Daily Test Volume, 2010
  • Japan, Total Coagulation Test Volume By Market Segment, 2010-2020
  • Japan, All Market Segments Coagulation Test Volume, 2010-2020
  • Japan, Hospital Laboratories Coagulation Test Volume, 2010-2020
  • Japan, Commercial/Private Laboratories Coagulation Test Volume, 2010-2020
  • Japan, Coagulation Reagent Market By Market Segment, 2010-2020
  • Japan, Major Suppliers of Coagulation Reagents Estimated Sales and Market Shares, 2010
  • Japan, Coagulation Instrument Market By Market Segment, 2010-2020
  • Japan, Major Suppliers of Coagulation Analyzers, Estimated Total Instrument Placements and Market Shares, 2010
  • Japan, Major Suppliers of Coagulation Analyzers, Estimated Placements and Installed Base By Supplier and Model, 2010
  • Japan, Major Suppliers of Coagulation Analyzers, Estimated Instrument Sales and Market Shares, 2010
  • Japan, Total Coagulation Diagnostics Market By Product Category, 2010-2020
  • Japan, Major Suppliers of Coagulation Diagnostic Products, Estimated Sales and Market Shares, 2010
  • Executive Summary Table: Spain, Total Coagulation Diagnostics Market By Market Segment and Product Category, 2010-2020
  • Spain, Laboratories Performing Coagulation Tests By Market Segment, 2010
  • Spain, Hospital Laboratories Performing Coagulation Tests By Bed Size, 2010
  • Spain, Commercial/Private Laboratories Performing Coagulation Tests By Annual Test Volume, 2010
  • Spain, Hospital Laboratories Average Daily Test Volume, 2010
  • Spain, Ambulatory Care Centers Average Daily Test Volume, 2010
  • Spain, Commercial/Private Laboratories Average Daily Test Volume, 2010
  • Spain, Total Coagulation Test Volume By Market Segment, 2010-2020
  • Spain, All Market Segments Coagulation Test Volume, 2010-2020
  • Spain, Hospital Laboratories Coagulation Test Volume, 2010-2020
  • Spain, Ambulatory Care Centers Coagulation Test Volume, 2010-2020
  • Spain, Commercial/Private Laboratories Coagulation Test Volume, 2010-2020
  • Spain, Coagulation Reagent Market By Market Segment, 2010-2020
  • Spain, Major Suppliers of Coagulation Reagents, Estimated Sales and Market Shares, 2010
  • Spain, Coagulation Instrument Market By Market Segment, 2010
  • Spain, Major Suppliers of Coagulation Analyzers, Estimated Total Instrument Placements and Market Shares, 2010
  • Spain, Major Suppliers of Coagulation Analyzers, Estimated Placements and Installed Base By Supplier and Model, 2010
  • Spain, Major Suppliers of Coagulation Analyzers, Estimated Instrument Sales and Market Shares, 2010 Spain, Total Coagulation Diagnostics Market By Product Category, 2010-2020
  • Spain, Major Suppliers of Coagulation Diagnostic Products, Estimates Sales and Market Shares, 2010
  • Executive Summary Table: U.K., Total Coagulation Diagnostics Market By Market Segment and Product Category, 2010-2020
  • U.K., Laboratories Performing Coagulation Tests By Market Segment, 2010
  • U.K., Hospital Laboratories Performing Coagulation Tests By Bed Size, 2010
  • U.K., Commercial/Private Laboratories Performing Coagulation Tests By Annual Test Volume, 2010
  • U.K., Hospital Laboratories Average Daily Test Volume, 2010 U.K., Commercial/Private Laboratories Average Daily Test Volume, 2010
  • U.K., Total Coagulation Test Volume By Market Segment, 2010-2020
  • U.K., All Market Segments Coagulation Test Volume, 2010-2020
  • U.K., Hospital Laboratories Coagulation Test Volume, 2010-2020
  • U.K., Commercial/Private Laboratories Coagulation Test Volume, 2010-2020
  • U.K., Coagulation Reagent Market By Market Segment, 2010-2020
  • U.K., Major Suppliers of Coagulation Reagents Estimated Sales and Market Shares, 2010
  • U.K., Coagulation Instrument Market By Market Segment, 2010
  • U.K., Major Suppliers of Coagulation Analyzers, Estimated Total Instrument Placements and Market Shares, 2010
  • U.K., Major Suppliers of Coagulation Analyzers, Estimated Placements and Installed Base By Supplier and Model, 2010
  • U.K., Major Suppliers of Coagulation Analyzers, Estimated Instrument Sales and Market Shares, 2010
  • U.K., Total Coagulation Diagnostics Market By Product Category, 2010-2020
  • U.K., Major Suppliers of Coagulation Diagnostic Products, Estimated Sales and Market Shares, 2010
  • Executive Summary Table: U.S.A., Total Coagulation Diagnostics Market By Market Segment and Product Category, 2010-2020
  • U.S.A., Laboratories Performing Coagulation Tests By Market Segment, 2010
  • U.S.A., Hospital Laboratories Performing Coagulation Tests By Bed Size, 2010
  • U.S.A., Commercial/Private Laboratories Performing Coagulation Tests By Annual Test Volume, 2010
  • U.S.A., Physician Offices/Group Practices Performing Coagulation Tests By Practice Size, 2010
  • U.S.A., Hospital Laboratories Average Daily Test Volume, 2010
  • U.S.A., Commercial/Private Laboratories Average Daily Test Volume, 2010
  • U.S.A., Physician Offices/Group Practices Average Daily Test Volume
  • U.S.A., Total Coagulation Test Volume By Market Segment, 2010-2020
  • U.S.A., All Market Segments Coagulation Test Volume, 2010-2020
  • U.S.A., Hospital Laboratories Coagulation Test Volume, 2010-2020
  • U.S.A., Physician Offices/Group Practices Coagulation Test Volume, 2010-2020
  • U.S.A., Commercial/Private Laboratories Coagulation Test Volume, 2010-2020
  • U.S.A., Coagulation Reagent Market By Market Segment, 2010-2020
  • U.S.A., Major Suppliers of Coagulation Reagents Estimated Sales and Market Shares, 2010
  • U.S.A., Coagulation Instrument Market By Market Segment, 2010-2020
  • U.S.A., Major Suppliers of Coagulation Analyzers, Estimated Total Instrument Placements and Market Shares, 2010
  • U.S.A., Major Suppliers of Coagulation Analyzers, Estimated Placements and Installed Base By Supplier and Model, 2010
  • U.S.A., Major Suppliers of Coagulation Analyzers, Estimated Instrument Sales and Market Shares, 2010
  • U.S.A., Total Coagulation Diagnostics Market By Product Category, 2010-2020
  • U.S.A., Major Suppliers of Coagulation Diagnostic Products, Estimated Sales and Market Shares, 2010
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