本報告已在2011年07月19日停止出版。
進行基因排序與蛋白質相關研究時,為了適當的保存、比較、整合龐大的資料,生物資訊是不可或缺的技術。此外在臨床層面上,高齡化讓醫療機構所需處理的患者資訊與日遽增,本領域對臨床資訊的需求也是節節高昇。
擅長多種尖端領域之產業策略性調查的美國專業公司 Technical Insights, Inc. (總公司:紐約),調查分析了生物資訊與臨床資訊發展後,出版了一本綜合報告書 “Advances in Bioinformatics and Clinical Informatics”。
報告書內容包括:生物資訊與臨床資訊的最新趨勢、基礎研究與醫療機構技術引進分析、技術研發促進要素、市場課題等等,內容綱要摘記如下:
1. 摘要
2. 技術與適用領域觀點
- 技術基礎
- 技術與適用領域分析
- 電子筆、電子紙、資料擷取器
- 疾病管理軟體
- 遠距治療/ e-Health
- 患者檢測系統
- 流行病學調查
- 專家評估:生物資訊的技術革新與技術轉移機會
- 大學、政府之主要研究機構需注意的技術革新
- 企業需注意的技術革新
- 專家評估:臨床資訊的技術革新與技術轉移機會
- 大學、政府之主要研究機構需注意的技術革新
- 企業需注意的技術革新
- 市場影響要素
- 規範/政策/其他
3. 技術引進要素分析
- 技術研發阻礙要素與市場課題:生物資訊
- 更多、更快、更好
- 市場細分化
- 系統整合與標準化
- 資料整合並非單純的系統整合
- 技術研發阻礙要素與市場課題:臨床資訊
- 技術引進促進要素
- 技術優點
4. 生物資訊的革命性發展
- 企業之生物資訊技術革新評價
- 發現新生物標的的軟體
- 革命性的生物標的檢測、驗證之生物晶片、軟體
- Web 基礎的微陣列分析
- 其他
- 主要市場企業
- Accelrys
- Iconix Pharmaceuticals
- Amersham
- Agilent Technologies
- Bio-Rad
- Scimagix
- SAS Institute
- MathWorks
- Orion Multisystems
- Sun Microsystems
- 生物資訊技術革新評價:北美
- 傳染病與基因相關 NCGR(美國國立基因資源中心)研究
- Open Bioinfomatics 財團的 BioPerl 計畫
- 其他
- 生物資訊技術革新評價:歐洲
- 蛋白質特定之生物資訊軟體
- 基因呈現實體工具(Ontology Toolkit)
- 其他
- 企業技術研發:歐洲與亞洲
- Nonlinear Dynamics
- Hybrigenics
- Solexa
- AlgoNomics
- Grid Innovation Zone
5. 臨床資訊的革命性發展
- 臨床資訊的技術革新評價
- 保存患者治療紀錄與基因資訊的 GMS(Genomic Messaging System)
- 先進的可視軟體:2 次元/3 次元/4 次元影像分析
- 用以正確治療之患者用條碼無線鏈(Wristband)
- 其他
- 主要市場企業
- Clinical Informatics
- 3M Health Information Systems
- Captaris/EMC
- Pfizer Health Solutions
- McKesson Corporation
- American Healthways
- Health Dialog
- WebMD Corp
- FileNet
- Prediction Sciences
6. Frost & Sullivan Award
7. 聯絡窗口/專利
8. 決策支援資料庫
Abstract
Need to Analyze Voluminous Data Opens up Exciting Opportunities for Bioinformatics
Genome sequencing and numerous studies related to proteins have left researchers grappling with massive quantities of data that is rapidly approaching a petabyte (over quadrillion bytes). Bioinformatics is fast emerging as the one-stop solution to store, manage, retrieve, organize, compare, and integrate the data all in a single computer. By using databases, tools, algorithms, and interfaces, bioinformatics is proving to be both a cost and time saving solution for handling complex biological information. Moreover, the increasing demand for automation and high throughput screening to study multiple genes and proteins simultaneously opens up additional opportunities for bioinformatics. This is evident from the increasing use of sensitive assay techniques, the integration of multiple techniques into a single platform, and the use of robotics across new age laboratories.
This Technical Insights research service provides a thorough analysis of the latest trends in the fields of bioinformatics and clinical informatics. The study analyzes key applications in different verticals such as basic research, drug discovery, and healthcare applications. In addition to identifying key technology drivers and industry challenges, participants can also identify potential collaborators, stay ahead of the competition, and keep abreast with critical developments.
Increasing Patient Population Drives Demand for Clinical Informatics
The increase in aging population and the consequent rise in patient data are driving healthcare systems, hospitals, and clinical researchers to invest in clinical informatics. With healthcare providers spending between 30 to 60 percent of their time on paperwork, clinical informatics is set to reduce healthcare costs and frequency of medical errors through faster and easier-to-use electronic systems.
For example, electronic medical records (EMR) allow all the information about a patient from disparate clinics and labs to be kept in a single and central record that can move with the patient. Systems such as hospital information systems (HIS) and electronic data management systems (EDMS) also manage these records along with billing and administration. "In search for quicker and more convenient access to critical patient information, researchers are now looking for a virtual clip-board, which can interact with every database and onto which they can post information of any format and type," says the analyst of this research service.
Advances in Bioinformatics Essential to Analyze Huge Data Quantities Derived from Microarrays
The increasing emphasis on understanding the interaction of numerous biomolecules and its impact on health is creating an urgent need for comprehensive bioinformatics solutions. In addition, tools such as microarrays that are used to analyze multiple samples on a single chip generate huge quantities of data in a short span of time thereby necessitating improvements bioinformatics.
Computer clusters and grids are changing the face of both bioinformatics and clinical informatics both of which require high-performance computing and enormous processing power. "Instead of buying one standard high-performance and expensive supercomputer, labs can now use software to link many PCs into powerful local networks, which ultimately proves to be more practical and affordable in the long term," explains the analyst.
Table of Contents
- 1. Scope and Methodology
- 2. Key Findings
- 1. Noteworthy Applications
- 2. Noteworthy Emerging Technologies
- 3. Assessment of Competing Technologies
2. Technology and Applications Viewpoint
- 1. Technology Primer
- 1. Databases
- 2. Middleware
- 3. Laboratory Information Management Systems
- 4. Clinical Informatics
- 2. Technology and Application Analysis
- 1. Digital Pen and Paper Data Capture
- 2. Disease Management Software
- 3. Telemedicine and eHealth
- 4. Patient Monitoring Systems
- 5. Epidemiological Surveillance
- 3. Assessment of Stakeholder Innovation and Technology Transfer Opportunities: Bioinformatics
- 1. Noteworthy Innovation at Key Academic and Government-Related Institutions
- 2. Noteworthy Innovation at Key Companies
- 4. Assessment of Stakeholder Innovation and Technology Transfer Opportunities: Clinical Informatics
- 1. Noteworthy Innovation at Key Academic and Government-Related Institutions
- 2. Noteworthy Innovation at Key Companies
- 5. Influential Market Factors: Bioinformatics and Clinical Informatics
- 1. Mergers & Acquisitions
- 2. Industry Trends and Assessments
- 6. Regulatory and Political or Other Factors
- 1. Electronic Document Management Systems
- 2. Standards Assessment
3. Technology Adoption Factor Analysis
- 1. Development Restraints and Market Challenges: Bioinformatics
- 1. More; Faster; Better
- 2. Market Fragmentation
- 3. Systems Integration and Standardization
- 4. Data Integration; Not Just Systems Integration
- 2. Development Restraints and Market Challenges: Clinical Informatics
- 1. Keep It Simple
- 2. Marketing: Web Presentation
- 3. Adoption Factors
- 1. Adoption Drivers: Bioinformatics
- 2. Adoption Drivers: Clinical Informatics
- 4. Technology Benefits
- 1. Technology Benefits: Bioinformatics
- 2. Technology Benefits: Clinical Informatics
4. Innovative Developments in Bioinformatics
- 1. Assessment of Bioinformatics Innovation--Companies
- 1. De Novo Sequencing Software to Discover New Biomarkers
- 2. Biochip Software for Detection and Validation of Novel Biomarkers
- 3. Web-Based Microarray Analysis
- 4. Lipomic Profiling to Help Prioritize Lead Compounds
- 5. Software App Offers Guided Analytics
- 6. Topomeric Drug Discovery
- 7. Blue Gene and Deep Computing
- 2. Key Market Participants
- 1. Accelrys
- 2. Iconix Pharmaceuticals
- 3. Amersham
- 4. Agilent Technologies
- 5. Bio-Rad
- 6. Scimagix
- 7. SAS Institute
- 8. MathWorks
- 9. Orion Multisystems
- 10. Sun Microsystems
- 3. Assessment of Bioinformatics Innovation in North America
- 1. NCGR Seeks Infectious Diseases Genetic Links
- 2. Microarray and Web Power
- 3. Wavestrapping: Learn More from Single Data Run
- 4. Biomolecular Interaction Network Database
- 5. BioPerl Project/The Open Bioinformatics Foundation
- 4. Assessment of Bioinformatics Innovation in Europe
- 1. 3-in-1 Bioinformatics Software for Protein Identification
- 2. Search by Semantics
- 3. Gene Expression Ontology Toolkit
- 5. Corporate Developments in Europe and Asia
- 1. Nonlinear Dynamics
- 2. Hybrigenics
- 3. Solexa
- 4. AlgoNomics
- 5. Grid Innovation Zone
5. Innovative Developments in Clinical Informatics
- 1. Assessment of Clinical Informatics Innovation
- 1. Genomic Messaging System Stores Patient Medical Records and Genetic Info
- 2. Advanced Visualization Software for 2D; 3D; and 4D Visualization Analysis
- 3. Media Servers Provide Wireless Communications Solution
- 4. Transmission of Vital Signs Data to Central Database
- 5. Bar-Coded Radio Wristband Ensures Accurate Patient Treatment
- 6. Software Predicts Healthcare Costs and Future Needs
- 7. BioSWAT Team
- 8. North American Academic; Nonprofit; and Government Research Groups
- 9. European Research
- 2. Key Market Participants
- 1. Clinical Informatics
- 2. 3M Health Information Systems
- 3. Captaris/EMC
- 4. Pfizer Health Solutions
- 5. McKesson Corporation
- 6. American Healthways
- 7. Health Dialog
- 8. WebMD Corp
- 9. FileNet
- 10. Prediction Sciences
6. Frost & Sullivan 2005 Science and Technology Awards
- 1. Excellence in Technology Award
- 1. Award Description
- 2. Award Recipient
- 2. Technology Leadership Award
- 1. Award Description
- 2. Award Recipient
- 3. Technology Innovation Award
- 1. Award Description
- 2. Award Recipient
7. Contacts and Patents
- 1. Contacts
- 1. Bioinformatics Companies
- 2. Genomics/Proteomics Companies
- 3. Microarray Companies
- 2. Patents
- 1. Patents 1
- 2. Patents 2
8. Critical Reference Tables
- 1. Decision Support Database
- 1. Government Healthcare Expenditure by Country
- 2. Per Capita Healthcare Expenditure by Country
- 3. Private Healthcare Expenditure by Country
- 4. Pharmaceutical R&D Expenditure by Country
- 5. Pharmaceutical R&D Expenditure as a Percentage of the Pharmaceutical Market