Trends in mammalian cell cultures
|出版商||Technical Insights (Frost & Sullivan)||商品編碼||334694|
|出版日期||內容資訊||英文 51 Pages
本報告提供全球哺乳動物細胞培養相關最新的技術、市場趨勢的分析，目前的技術能力，及技術方面的價值鏈，主要的推動及阻礙市場要素及應克服的障礙，全球各地的新技術引進的動向，未來的市場機會和今後的革新 (技術創新) 的方向性，對技術/產品與服務開發業者的建議等項目調查、考察。
Technology Market Penetration and Roadmapping
With the growing need for better therapeutics, and the current patent cliff that is underway, therapies such as monoclonal antibodies, recombinant protein therapeutics and even vaccines for a whole host of indications are in high demand. Conventionally expression systems were utilized to aid in the development and production of these therapeutics. However, due to issues with low yields, poor quality and high costs, novel approaches and novel expression systems are currently being discovered.
Mammalian expression systems are the most rapidly growing segment across all expression systems, and their utility has now been advanced with the capability to integrate more technologies together such as genome editing technologies and genetic manipulation technologies. Mammalian expression systems are mostly developed using Chinese Hamster Ovary (CHO) cells and HEK-293 (Human Embryonic Kidney) cells. There have been no significant changes with respect to the cell-types used. Developments have been incremental, with emphasis on production efficiency, yield, DNA vectors used for cell transfection, and the breadth of recombinant products derived from the expression system.
This research service brings out the emerging trends in mammalian cell culture systems on a global scale, through a detailed description of: