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市場調查報告書
GPCR（G蛋白質偶合受體）藥劑標的受體的新興技術
Emerging Technologies in GPCR-Based Drug Target Receptors
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GPCR（G蛋白質偶合受體）藥劑標的受體的新興技術 是由出版商Technical Insights, Inc.在2009年09月所出版的。
這份英文市場調查報告書價格從美金6500起跳。
本報告書內容包括:GPCR（G蛋白質偶合受體）創藥技術的動向檢證、産業界及學術界的技術開發最新動向、內容綱要摘記如下:
第1章 實施摘要
第2章 技術概要和引進因素
- 技術概要
- 訊號變換過程
- 生物學和GPCR（G蛋白質偶合受體）的分類
- GPCR的細胞分析
第3章 GPCR領域的主要開發動向
- 産業界的開發
- GPCR-HIT所使用的新一代藥劑開發
- GPCR二量體識別技術
- 低分子重量和藥劑樣分子的GPCR化合物圖書館
- GPCR的奈米體平台
- GPCR的新型變換縮氨酸配體創藥
- GPCR的高效能測定
- GPCR蛋白質為標的時的高發現哺乳類細胞
- GPCR的小分子圖書館
- GPCR及其他標的檢測所需的蛋白質・斷片補足所用的新式分析法
- GPCR的個別分析服務
- 代謝性疾病的島細胞治療
- GPCR的蛋白質模樣技術
- 學術界的開發
- 研究者為決定膜蛋白質的結構而使用NMR
- GPCR檢測讓神經元保護受體明朗化
第4章 技術分析和引進因素
第5章 專利・業界加入企業
第6章 決策支援資料庫
Abstract
This research service outlines the technologies for GPCR Drug Discovery.
Table of Contents
1. Executive Summary
Research Overview and Highlights
- GPCRs: Versatility Unparalleled Yet Potential Untapped
- Key Highlights of the Research Service
Scope and Methodology
- Scope and Segmentation
- Methodology
2. Technology Primer and Adoption Factors
Technology Primer
- The Process of Signal Transduction--A Snapshot
- Biology and Classification of GPCRs
Cell-Based Assays for GPCRs
- Cell-Based Assays--An Introduction
- Applications of Cell-Based Assays
3. Key Developments in the GPCR Space
Developments across the Industry
- Developing Next Generation Drugs Using GPCR-HIT
- GPCR Dimer Identification Technology
- GPCR Compound Libraries for Low Molecular Weight and Drug-Like Molecules
- Nanobody Platform for GPCRs
- Novel Peptide Ligand Discovery for GPCRs
- Novel High-Throughput Assay for GPCRs
- High-Expression Mammalian Cell Lines Aide in Targeting GPCR Proteins
- Small Molecule Libraries for GPCRs - NCEs
- Novel Assay Uses Protein-Fragment Complementation to Screen GPCRs and
Other Targets in Their Native Cellular Context
- Personalized Assay Services for GPCRs
- Islet Therapy for Metabolic Diseases
- Protein Mimicry Technology for GPCRs
Developments across Academia
- Researchers Use NMR to Determine the Structure of Membrane Proteins
- GPCR Screening Reveals Receptors Involved in Neuronal Protection
4. Technology Analysis and Adoption Factors
Force Field Analysis--Drug Discovery for GPCRs
- Growth Accelerators
- Technology Barriers
Strategic Analysis of the Industry--Cell Based Assays for GPCRs
- Porter' s Analysis for the Cell-Based Assays Industry
- Strategic Recommendations for the Industry
5. Patents and Key Participants
List of Patents
- Patents across the Industry
- Patents across Academia
Key Participants
- Industry Participants
- Academic Participants
6. Decision Support Database
DSD Tables
- Number of Biotech Companies (Million USD)--World (2004 to 2014)
- Percentage Pharmaceutical R&D Expenditure (Million USD)--World (2004 to
2014)
- Pharmaceutical Market (Million USD)--World (2004 to 2014)
- Venture Capital Investment in Biotech R&D (Million USD)--World (2004 to
2014)
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