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市場調查報告書
單細胞組學：進展與革命
Single Cell Omics: Evolution and Revolution
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單細胞組學：進展與革命 是由出版商Select Biosciences, Ltd.在2011年05月所出版的。
這份英文市場調查報告書包含167 Pages 價格從美金4205起跳。
本報告書為單細胞組學的主要技術與應用領域、為滿足需求動向等整理，概述如下。
第1章 總綱
第2章 歷史的展望
第3章 細胞的不均一性
第4章前端技術
- 技術概要
- 前端導論
- 調査項目
- FACS調整細胞排序
- 磁珠調整細胞排序
- 顯微鏡的擷取／微操作
- 雷射擷取顯微解剖
第5章 後端技術
- 導論
- 最新動向
- 技術概要
- 調査項目
- 最新事例
- 將來方向性
第6章 前端與後端的橋梁
- 導論
- 第1世代平台案例
- 第2世代平台案例
- 調査項目
第7章 新興的應用
第8章 市場模式
第9章 競爭環境
- 導論
- 循環腫瘤細胞／稀少細胞
- DNA測序
- 微流體
- 顯微鏡擷取與其他
Abstract
The single cell Omics revolution is the potential transformation of cellular
heterogeneity from a source of noise to a source of new, as yet hidden
discoveries. No longer will the variability from one cell to the next confound
researchers and force them to average results into irrelevance. Researchers
may find, in fact, that this variability is critical for cells to respond to
and interact with their environments. But even without the complete
revolution, single cell Omics offer significant evolutionary advances in
fields of biology and medicine that are already based on single cell analysis,
such as immunology, neurobiology, stem cell biology, circulating tumor cells
and preimplantation genetic diagnosis. Moreover, the ongoing evolution of
single cell Omics technologies provides improvements in sensitivity and
throughput that will enable researchers to generate more data from smaller
numbers of cells, which can be enabling in cases of precious samples. The
result of this (r)evolution is a market for Omics technologies that is
projected to grow from $60 million in sales in 2010 to $525 million in 2016,
according to Single Cell Omics 2011, a new report published by Select
Biosciences and written by BioPerspectives.
Survival of the fittest requires a detailed understanding of this emerging
market. Single Cell Omics 2011 explains the key technologies, applications,
unmet needs and trends. The 167-page report includes an Internet survey
administered to a large stratified database; analyses of front-end separation
technologies, back-end Omics technologies and integrated platforms to bridge
the gap; profiles of 30 companies; and a quantitative market model segmented
by technologies. In addition, the report comes with a reprint of the Trends in
Biotechnology cover article written by two of the report authors. Moreover,
the report also comes with one hour of consulting (in the form of a conference
call) with report authors Dr. Bodovitz, Principal of BioPerspectives or Antje
Plaschke-Schluetter, Head of Application at Molecular Machines & Industries
AG. To order a copy of the report and increase your fitness, please click here.
Table of Contents
Chapter 1: Executive Summary
- Introduction
- Cellular Heterogeneity
- Front-End Isolation of Single Cells
- Back-End Isolation of Single Cells
- Bridging Front- and Back-End
- Applications
- Competitive Environment
- Trends in Usage
- Prediction of Market Inflections
- Market Model
Chapter 2: Historical Perspective
- Single Cells
- Omics
- Omics and Small Numbers of Cells
- Omics and Single Cells
Chapter 3: Cellular Heterogeneity
- Introduction
- Specific Examples of Heterogeneity
- RNA Interference
- Gene Expression Profiles in C. Elegans
- More Examples of Heterogeneity
- Root Cause
- Survey Question
- Significance
- From Noise to Discoveries
- The Trend
- Survey Question
Chapter 4: Front-End Technologies
- Overview of Technologies
- Introduction to the Front-End
- Survey Question
- FACS-Mediated Cell Sorting
- Magnetic Bead-Mediated Cell Sorting
- Microscopic Capture/Micromanipulation
- Laser Capture Microdissection
Chapter 5: Back-End Technologies
- Introduction
- State-of-the-Art
- Technology Overview
- Survey Question
- Examples of State of the Art
- Genomics
- Survey Question
- Metabolomics
- Survey Questions
- Microfluidic Interface with Mass Spectrometry
- Future Directions
Chapter 6: Bridging the Front- and Back-Ends
- Introduction
- Examples of First-Generation Platforms
- Examples of Second-Generation Platforms
- Silicon Biosystems
- Microcavity Array
- Single Cell Microarray
- Survey Question
Chapter 7: Emerging Applications
- Introduction
- Literature Analysis
- Established
- Preimplantation Genetic Diagnosis/Screening
- Established/Emerging
- Stem Cells
- Immunology
- Neurobiology
- Emerging
- Cancer
- Circulating Tumor Cells
- Introduction
- Workflow 1
- Workflow 2
- Workflow 3
- Workflow 4
- Workflow 5
- Systems Biology
Chapter 8: Market Model
- Methodology
- Literature Analysis
- Survey Questions
- Market Model
- Overall Technology Markets
- Top-Down Analysis for 2010
- Growth Projections
Chapter 9: Competitive Environment
- Introduction
- Circulating Tumor Cells/Rare Cells
- Adnagen
- Biocept
- Cytotrack
- Rarecells
- Silicon Biosystems
- Veridex
- DNA Sequencing
- IBM
- IonTorrent
- Oxford Nanopore Technologies
- Pacific Biosciences
- Microfluidics
- BioNanomatrix
- Cyntellect
- Fluidigm
- Fluxion Biosciences
- IntegenX
- Mathies Lab
- Microfluidic ChipShop
- RainDance Technologies
- Microscopic Capture
- Eppendorf
- Hacker Instruments
- Ibidi
- Leica Microsystems
- MMI
- Narishige
- Zeiss
- Multifaceted
- Life Technologies
- Miltenyi Biotec
- Roche Applied Science
- TATAA Biocenter
- Outside-the-Box
- Preimplantation Genetic Diagnosis
Appendix: Methodology
- Author Credentials
- Sources
- Market Model
- Literature Analysis
- Internet Survey
- Background Question 1
- Background Question 2
- Background Question 3
- Background Question 4
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