Abstract
Nucleic acid purification is one of the few basic methods ubiquitous among
scientists using molecular biology techniques to investigate processes such as
gene expression, genetic diversity, protein function and molecular
interactions. The Nucleic Acid Purification Dashboard was developed from
responses to a 20-question survey of 488 scientists predominantly located in
North America and Europe. This Dashboard reveals key market indicators for the
nucleic acid purification market as a whole as well as for the following
sub-segments:
- Plasmid minipreps (1-2 ml of culture)
- Plasmid midipreps (5-50 ml of culture)
- Large scale plasmid preps/maxipreps (100 ml or more of culture)
- Genomic DNA purification from cells & tissues and whole blood
- Total RNA purification from cells & tissues and whole blood
- mRNA purification
- microRNA purification
Percepta' s 2009 Nucleic Acid Purification Dashboard"! is a deep dive into the
characteristics and dynamics of the market for nucleic acid purification
products. This 2009 Dashboard provides a snapshot of the current market
landscape that can be compared with data from the 2007 Nucleic Acid Dashboard,
providing an ongoing story of how the market is adapting to new products, new
competitors, acquisitions and new sales and marketing strategies.
Survey Methodology
In April of 2009, Percepta fielded the Nucleic Acid Purification Survey to a
subset of the Percepta BioAnalytix"! Panel of life scientists. Individuals
were invited by e-mail blast to click through to a webpage at
perceptabioanalytix.com where the survey was hosted. Invitations were
delivered beginning on April 2, 2009 and results collected through May 1,
2009. A total of 488 scientists participated in the survey, of which 433 are
actively engaged in performing nucleic acid purification and 4 plan to use
nucleic acid purification methods in the next 12 months. Results based on the
aggregate of collected responses are revealed in this Nucleic Acid
Purification Dashboard. Important Note: This report only includes analyses
related to the research market for nucleic acid purification products and not
the market for products used in diagnostic assays.
Respondent Demographics
Respondents from the academic, government and commercial market segments are
well represented. 52.2% of respondents work at universities/colleges/medical
schools; 8.2% are employed at hospitals/medical centers. 13.8% of respondents
work for biotechnology companies; 9.4% are employed by pharmaceutical
companies. Overall, 25.0% of respondents work in industrial laboratories.
74.8% of respondents are from North America (66.6% in the United States and
8.2% in Canada), while 23.0% reside in Europe.
Junior (Lab Tech, Grad Students), mid level (Post-Doc, Lab Manager) and senior
(Professor/PI, Group Leader) scientists are well represented in the data set,
with the most cited job titles being Scientist/Senior Scientist (32.0% of
respondents) and Professor/Principal Investigator (15.6%).
A wide variety of scientific areas of specialization is also evident, led by
Cell Biology and Biochemistry (each indicated by 13.7% of respondents as their
primary area of expertise), Genomics (13.0%) and Microbiology/Infectious
Disease/ Virology (12.6%).
Small (1-5 scientists), medium (6-20 scientists) and large (>20 scientists)
laboratories are well represented. 52.0% of respondents are from laboratories
where between 1 and 5 scientists perform nucleic acid purification. 34.8% of
respondents work in labs where between 6 and 20 people culture mammalian
cells, while the remaining 13.3% are from labs where more than 20 people
perform this technique.
Table of Contents
Figures and Tables
- 11 Executive Summary
- 13 Key Findings and Implications
- 18 Nucleic Acid Purification Dashboard
- 23 Nucleic Acid Purification Market Opportunity Matrix
- 25 Survey Methodology
- 27 Survey Invitation Text
- 28 Respondent Demographics
- 40 Frequency of Performance of Life Science Techniques
- 45 Frequency of Nucleic Acid Purification Product Use
- 62 Throughput/Usage Rates and Market Growth Rates
- 68 Respondent' s Stated Price for Nucleic Acid Purification Products
- 71 Total Market Size, Market Segment Sizes and Total Market Growth Rate
- 73 Market Shares by Segment (Share of Mention)
- 113 Customer Satisfaction And Interest In Switching Suppliers
- 119 Product Features That Influence Purchasing Decisions
- 123 Primary and Secondary Downstream Applications
- 152 Desired Changes to Nucleic Acid Purification Products
- 162 Survey Questionnaire
List of Figures
- 30 Figure 1: Respondent' s Place of Employment
- 32 Figure 2: Respondent' s Country/Region
- 33 Figure 3: Respondent' s Job Title
- 35 Figure 4: Respondent' s Areas of Expertise/Specialization
- 39 Figure 5: Number of Employees in Respondent' s Laboratories
- 42 Figure 6: Percentage of Respondents Performing Various Life Science
Techniques at Least a Few Times per Year
- 47 Figure 7: Percentage of Respondents Performing Nucleic Acid Purification
- 48 Figure 8: Percentage of Respondents Using Various Types of Nucleic Acid
Purification Products in Their Laboratories
- 50 Figure 9: Percentage of Respondents Performing Plasmid Miniprep
Isolation
- 51 Figure 10: Percentage of Respondents Performing Plasmid Midiprep
Isolation
- 52 Figure 11: Percentage of Respondents Performing Plasmid Large Scale
Isolation
- 53 Figure 12: Percentage of Respondents Performing Genomic DNA Isolation
from Cells or Tissue
- 54 Figure 13: Percentage of Respondents Performing Genomic DNA Isolation
from Whole Blood
- 55 Figure 14: Percentage of Respondents Performing Total RNA Isolation
from Cells or Tissue
- 56 Figure 15: Percentage of Respondents Performing Total RNA Isolation
from Whole Blood
- 57 Figure 16: Percentage of Respondents Performing mRNA Isolation
- 58 Figure 17: Percentage of Respondents Performing microRNA Isolation
- 75 Figure 18: Respondent' s Primary Supplier for Plasmid Miniprep
Purification Products
- 79 Figure 19: Respondent' s Primary Supplier for Plasmid Midiprep
Purification Products
- 83 Figure 20: Respondent' s Primary Supplier for Plasmid Large Scale
Plasmid Purification Products
- 88 Figure 21: Respondent' s Primary Supplier for Purifying Genomic DNA from
Cells or Tissue
- 92 Figure 22: Respondent' s Primary Supplier Purifying Genomic DNA from
Whole Blood
- 97 Figure 23: Respondent' s Primary Supplier for Purifying Total RNA from
Cells or Tissue
- 101 Figure 24: Respondent' s Primary Supplier for Purifying Total RNA from
Whole Blood
- 105 Figure 25: Respondent' s Primary Supplier for Purifying mRNA
- 109 Figure 26: Respondent' s Primary Supplier for Purifying microRNA
- 118 Figure 27: Percentage of Respondents That Have Switched Suppliers in
the Last Six Months
- 121 Figure 28: Most Important Features of Nucleic Acid Purification
Products
- 125 Figure 29: Respondent' s Primary Application for Purified Plasmid
Miniprep DNA
- 126 Figure 30: Respondent' s Primary & Secondary Applications for Purified
Plasmid Miniprep DNA
- 127 Figure 31: Respondent' s Primary Application for Purified Plasmid
Midiprep DNA
- 128 Figure 32: Respondent' s Primary & Secondary Applications for Purified
Plasmid Midiprep DNA
- 129 Figure 33: Respondent' s Primary Application for Purified Plasmid
Maxiprep DNA
- 130 Figure 34: Respondent' s Primary & Secondary Applications for Purified
Plasmid Maxiprep DNA
- 133 Figure 35: Respondent' s Primary Application for Genomic DNA Isolated
from Cells and Tissue
- 134 Figure 36: Respondent' s Primary & Secondary Applications for Genomic
DNA Isolated from Cells and Tissue
- 135 Figure 37: Respondent' s Primary Application for Genomic DNA Isolated
from Whole Blood
- 136 Figure 38: Respondent' s Primary & Secondary Applications for Genomic
DNA Isolated from Whole Blood
- 139 Figure 39: Respondent' s Primary Application for Total RNA Isolated
from Cells and Tissue
- 140 Figure 40: Respondent' s Primary & Secondary Applications for Total RNA
Isolated from Cells and Tissue
- 141 Figure 41: Respondent' s Primary Application for Total RNA Isolated
from Whole Blood
- 142 Figure 42: Respondent' s Primary & Secondary Applications for Total RNA
Isolated from Whole Blood
- 145 Figure 43: Respondent' s Primary Application for Purified mRNA
- 146 Figure 44: Respondent' s Primary & Secondary Applications for Purified
mRNA
- 149 Figure 45: Respondent' s Primary Application for Purified microRNA
- 150 Figure 46: Respondent' s Primary & Secondary Applications for Purified
microRNA
List of Tables
- 36 Table 1: Respondent' s Areas of Expertise/Specialization Values for
Figure 4
- 43 Table 2: Frequency of Performance of Various Life Science Techniques
- 44 Table 3: Frequency of Co-Performance of Various Life Science Techniques
- 49 Table 4: Frequency of Use for Various Nucleic Acid Purification Products
- 60 Table 5: Frequency of Co-Performance of Life Science Techniques with
the Use of Various Nucleic Acid Purification Products
- 61 Table 6: Frequency of Use of Nucleic Acid Purification Products with
the Performance of Life Science Techniques
- 64 Table 7: Median and Average Monthly Usage Rates for Nucleic Acid
Purification Products
- 65 Table 8: Percentage of Respondents Performing Various Numbers of
Purification Reactions per Month by Product Category
- 67 Table 9: Projected Growth in the Use of Various Nucleic Acid
Purification Product Categories
- 70 Table 10: Median and Average Price Per Prep for Nucleic Acid
Purification Products
- 72 Table 11: Estimated 2009 Global Market Size for Nucleic Acid
Purification Products by Category
- 77 Table 12: Respondent' s Primary Supplier for Plasmid Miniprep
Purification Products by Market Segment
- 81 Table 13: Respondent' s Primary Supplier for Plasmid Midiprep
Purification Products by Market Segment
- 85 Table 14: Respondent' s Primary Supplier for Plasmid Maxiprep
Purification Products by Market Segment
- 86 Table 15: Market Share Leaders for Plasmid Purification Products
- 90 Table 16: Respondent' s Primary Supplier for Purifying Genomic DNA from
Cells or Tissue by Market Segment
- 94 Table 17: Respondent' s Primary Supplier for Purifying Genomic DNA from
Whole Blood by Market Segment
- 95 Table 18: Market Share Leaders for Genomic DNA Purification Products
- 99 Table 19: Respondent' s Primary Supplier for Purifying Total RNA from
Cells or Tissue by Market Segment
- 103 Table 20: Respondent' s Primary Supplier for Purifying Total RNA from
Whole Blood by Market Segment
- 107 Table 21: Respondent' s Primary Supplier for Purifying mRNA by Market
Segment
- 111 Table 22: Respondent' s Primary Supplier for Purifying microRNA by
Market Segment
- 112 Table 23: Respondent' s Primary Application for Nucleic Acid
Purification Categories - Comparison to 2007 Nucleic Acid Purification
Dashboard
- 115 Table 24: Percentage of Respondents Satisfied with Various Nucleic
Acid Purification Product Categories and Reasons for Dissatisfaction
- 116 Table 25: Percentage of Respondents Satisfied with Nucleic Acid
Purification Product Categories - Comparison to 2007 Nucleic Acid
Purification Dashboard
- 122 Table 26: Most Important Features of Products for Nucleic Acid
Purification - Comparison to 2007 Nucleic Acid Dashboard
- 147 Table 27: Respondent' s Primary & Secondary Applications for mRNA -
Comparison to 2007 Nucleic Acid Purification Dashboard
- 151 Table 28: Respondent' s Primary & Secondary Applications for microRNA
- Comparison to 2007 Nucleic Acid Purification Dashboard
