Abstract
Overview
Nucleic acid purification is one of the few basic methods ubiquitous among
scientists using molecular biology techniques to investigate processes such as
gene expression, genetic diversity, protein function and molecular
interactions. The Nucleic Acid Purification Dashboard was developed from
responses to a 20-question survey of 506 scientists predominantly located in
North America and Europe. This Dashboard reveals key market indicators for the
nucleic acid purification market as a whole as well as for the following
sub-segments:
- Gel extraction
- Post-reaction cleanup (i.e. PCR, enzyme digestion)
- Plasmid DNA minipreps (1-2 ml culture)
- Plasmid DNA midipreps (5-50 ml culture)
- Plasmid DNA maxipreps (100 ml culture or more)
- Genomic DNA from cells or tissue
- Genomic DNA from whole blood
- Genomic DNA from FFPE tissue
- Total RNA from cells or tissue
- Total RNA from whole blood
- Total RNA from FFPE tissue
- mRNA
- microRNA
Percepta' s 2011 Nucleic Acid Purification Dashboard"! is a deep dive into the
characteristics and dynamics of the market for nucleic acid purification
products. This 2011 Dashboard provides a snapshot of the current market
landscape that can be compared with data from the 2009 Nucleic Acid Dashboard,
providing an ongoing story of how the market is adapting to new products, new
competitors, acquisitions and new sales and marketing strategies.
Survey Methodology
In July of 2011, Percepta fielded the Nucleic Acid Purification Survey to a
subset of the Percepta BioAnalytix"! Panel of life scientists. Individuals
were invited by e-mail blast to click-through to a webpage at
perceptabioanalytix.com where the survey was hosted. Invitations were
delivered beginning on July 16, 2011 and results collected through July 29,
2011. A total of 506 scientists participated in the survey, of which 486 are
actively engaged in performing nucleic acid purification and 12 plan to use
nucleic acid purification methods in the next 12 months. Results based on the
aggregate of collected responses are revealed in this Nucleic Acid
Purification Dashboard.
Important Note: This report only includes analyses related to the research
market for nucleic acid purification products and not the market for products
used in diagnostic assays.
Respondent Demographics
Respondents from the academic, government and commercial market segments are
well represented. 52.0% of respondents work at universities/colleges/medical
schools; 8.3% are employed at hospitals/medical centers. 14.0% of respondents
work for biotechnology companies; 8.5% are employed by pharmaceutical
companies. Overall, 24.7% of respondents work in industrial laboratories and
72.9% of respondents work in academic laboratories.
67.6% of respondents are from North America (61.7% in the United States and
5.9% in Canada), while 31.4% reside in Europe.
Junior, mid-level and senior scientists are well represented in the data set,
with the most cited job titles being Scientist/Senior Scientist (33.4% of
respondents) and Professor/Principal Investigator (16.0%).
A wide variety of scientific areas of specialization is also evident, led by
Molecular Biology (indicated by 28.3% of respondents as their primary area of
expertise), Cell Biology (12.8%) and Biochemistry (12.5%).
Small (1-5 scientists), medium (6-20 scientists) and large (>20 scientists)
laboratories are well represented. 46.3% of respondents are from laboratories
where between 1 and 5 scientists perform nucleic acid purification. 42.9% of
respondents work in labs where between 6 and 20 people isolate nucleic acids
while the remaining 10.9% are from labs where more than 20 people perform
nucleic acid isolation.
The three most common primary organisms that scientists work with when
performing nucleic acid purification are: human (indicated by 38.3% of
respondents), bacteria (29.6%) and mouse (16.0%)
Table of Contents
- Executive Summary
- Key Findings and Implications
- Nucleic Acid Purification Dashboard
- Nucleic Acid Purification Market Opportunity Matrix
- Survey Methodology
- Survey Invitation Text
- Respondent Demographics
- Frequency of Performance of Life Science Techniques
- Frequency of Nucleic Acid Purification Product Use
- Frequency of Co-Performance of Techniques and Methods
- Throughput/Usage Rates and Market Growth Rates
- Stated Price for Nucleic Acid Purification Products
- Market Segment Sizes, Total Market Size and Total Market Growth Rate
- Market Shares by Segment (Share of Mention)
- Customer Satisfaction And Interest In Switching Suppliers
- Product Features That Influence Purchasing Decisions
- Primary and Secondary Downstream Applications
- Desired Changes to Nucleic Acid Purification Products
- Survey Questionnaire
- Appendix
List of Figures
- Figure 1: Respondents' Place of Employment
- Figure 2: Respondents' Country/Region
- Figure 3: Respondents' Job Title
- Figure 4: Respondents' Areas of Expertise/Specialization
- Figure 5: Number of Employees in Respondents' Laboratories
- Figure 6: Respondents' Primary and Secondary Species Focus
- Figure 7: Percentage of Respondents Performing Various Life Science
Techniques at Least a Few Times per Year
- Figure 8: Percentage of Respondents Performing Nucleic Acid Purification
- Figure 8A: Change in Percentage of Respondents Performing Nucleic Acid
Purification
- Figure 9: Percentage of Respondents Using Various Types of Nucleic Acid
Purification Products in Their Laboratories
- Figure 10: Percentage of Respondents Performing Gel Extraction
- Figure 11: Percentage of Respondents Performing Post-reaction Cleanup
- Figure 12: Percentage of Respondents Performing Plasmid DNA Miniprep
Purification
- Figure 12A: Change in Percentage of Respondents Performing Plasmid DNA
Miniprep Purification
- Figure 13: Percentage of Respondents Performing Plasmid DNA Midiprep
Purification
- Figure 13A: Change in Percentage of Respondents Performing Plasmid DNA
Midiprep Purification
- Figure 14: Percentage of Respondents Performing Plasmid DNA Maxiprep
Purification
- Figure 14A: Change in Percentage of Respondents Performing Plasmid DNA
Maxiprep Purification
- Figure 15: Percentage of Respondents Performing Genomic DNA Purification
from Cells or Tissue
- Figure 15A: Change in Percentage of Respondents Performing Genomic DNA
Purification from Cells or Tissue
- Figure 16: Percentage of Respondents Performing Genomic DNA Purification
from Whole Blood
- Figure 16A: Change in Percentage of Respondents Performing Genomic DNA
Purification from Whole Blood
- Figure 17: Percentage of Respondents Performing Genomic DNA Purification
from FFPE Tissue
- Figure 18: Percentage of Respondents Performing Total RNA Purification
from Cells or Tissue
- Figure 18A: Change in Percentage of Respondents Performing Total RNA
Purification from Cells or Tissue
- Figure 19: Percentage of Respondents Performing Total RNA Purification
from Whole Blood
- Figure 19A: Change in Percentage of Respondents Performing Total RNA
Purification from Whole Blood
- Figure 20: Percentage of Respondents Performing Total RNA Purification
from FFPE Tissue
- Figure 21: Percentage of Respondents Performing mRNA Purification
- Figure 21A: Change in Percentage of Respondents Performing mRNA
Purification
- Figure 22: Percentage of Respondents Performing microRNA Purification
- Figure 22A: Change in Percentage of Respondents Performing microRNA
Purification
- Figure 23: Respondents' Primary Supplier for Gel Extraction Products
- Figure 24: Respondents' Primary Supplier for Post-reaction Cleanup Products
- Figure 25: Respondents' Primary Supplier for Plasmid DNA Miniprep
Purification Products
- Figure 25A: Change in Mention of Primary Supplier for Plasmid DNA Miniprep
Purification Products Purification Products
- Figure 26A: Change in Mention of Primary Supplier for Plasmid DNA Midiprep
Purification Products
- Figure 27: Respondents' Primary Supplier for Plasmid DNA Maxiprep
Purification Products
- Figure 27A: Change in Mention of Primary Supplier for Plasmid DNA Maxiprep
Purification Products
- Figure 28: Respondents' Primary Supplier for Purifying Genomic DNA from
Cells or Tissue
- Figure 28A: Change in Mention of Primary Supplier for Purifying Genomic
DNA from Cells or Tissue
- Figure 29: Respondents' Primary Supplier for Purifying Genomic DNA from
Whole Blood
- Figure 29A: Change in Mention of Primary Supplier for Purifying Genomic
DNA from Whole Blood
- Figure 30: Respondents' Primary Supplier for Purifying Genomic DNA from
FFPE Tissue
- Figure 31: Respondents' Primary Supplier for Purifying Total RNA from
Cells or Tissue
- Figure 31A: Change in Mention of Primary Supplier for Purifying Total RNA
from Cells or Tissue
- Figure 32: Respondents' Primary Supplier for Purifying Total RNA from
Whole Blood
- Figure 32A: Change in Mention of Primary Supplier for Purifying Total RNA
from Whole Blood
- Figure 33: Respondents' Primary Supplier for Purifying Total RNA from FFPE
Tissue
- Figure 34: Respondents' Primary Supplier for Purifying mRNA
- Figure 34A: Change in Mention of Primary Supplier for Purifying mRNA
- Figure 35: Respondents' Primary Supplier for Purifying microRNA
- Figure 35A: Respondents' Primary Supplier for Purifying microRNA
- Figure 36: Percentage of Respondents That Have Switched Suppliers in the
Last Six Months
- Figure 37: Most Important Features of Products for Nucleic Acid
Purification
- Figure 38: Respondents' Primary Application for Purified Gel Extraction
Nucleic Acids
- Figure 39: Respondents' Primary & Secondary Applications for Purified Gel
Extraction Nucleic Acids
- Figure 40: Respondents' Primary Application for Purified Post-reaction
Cleanup Nucleic Acids
- Figure 41: Respondents' Primary & Secondary Applications for Purified
Post-reaction Cleanup Nucleic Acids
- Figure 42: Respondents' Primary Application for Purified Plasmid Miniprep
DNA
- Figure 43: Respondents' Primary & Secondary Applications for Purified
Plasmid Miniprep DNA
- Figure 44: Respondents' Primary Application for Purified Plasmid Midiprep
DNA
- Figure 45: Respondents' Primary & Secondary Applications for Purified
Plasmid Midiprep DNA
- Figure 46: Respondents' Primary Application for Purified Plasmid Maxiprep
DNA
- Figure 47: Respondents' Primary & Secondary Applications for Purified
Plasmid Maxiprep DNA
- Figure 48: Respondents' Primary Application for Genomic DNA Purified from
Cells or Tissue
- Figure 49: Respondents' Primary & Secondary Applications for Genomic DNA
Purified from Cells or Tissue
- Figure 50: Respondents' Primary Application for Genomic DNA Purified from
- Figure 51: Respondents' Primary & Secondary Applications for Genomic DNA
Purified from Whole Blood
- Figure 52: Respondents' Primary Application for Genomic DNA Purified from
FFPE Tissue
- Figure 53: Respondents' Primary & Secondary Applications for Genomic DNA
Purified from FFPE Tissue
- Figure 54: Respondents' Primary Application for Total RNA Purified from
Cells or Tissue
- Figure 55: Respondents' Primary & Secondary Applications for Total RNA
Purified from Cells or Tissue
- Figure 56: Respondents' Primary Application for Total RNA Purified from
Whole Blood
- Figure 57: Respondents' Primary & Secondary Applications for Total RNA
Purified from Whole Blood
- Figure 58: Respondents' Primary Application for Total RNA Purified from
FFPE Tissue
- Figure 59: Respondents' Primary & Secondary Applications for Total RNA
Purified from FFPE Tissue
- Figure 60: Respondents' Primary Application for Purified mRNA
- Figure 61: Respondents' Primary & Secondary Applications for Purified mRNA
- Figure 62: Respondents' Primary Application for Purified microRNA
- Figure 63: Respondents' Primary & Secondary Applications for Purified
microRNA
- Figure 64: Non-current Users of Nucleic Acid Purification Products -
Future Plans
List of Tables
- Table 1: Respondents' Areas of Expertise/Specialization (Values for Figure
4)
- Table 2: Frequency of Performance of Various Life Science Techniques
- Table 3: Frequency of Co-Performance of Various Life Science Techniques
- Table 4: Frequency of Use for Various Nucleic Acid Purification Products
- Table 5: Frequency of Co-Performance of Life Science Techniques with
Various Nucleic Acid Purification Methods
- Table 6: Frequency of Co-Performance of Nucleic Acid Purification Methods
with Various Life Science Techniques
- Table 7: Co-Performance of Various Nucleic Acid Purification Methods
- Table 8: Median and Average Monthly Throughput for Nucleic Acid
Purification Methods
- Table 8A: Change in Median Monthly Throughput for Nucleic Acid
Purification Methods
- Table 9: Percentage of Respondents Performing Various Numbers of
Purification Reactions Per Month
- Table 10: Projected Growth Rates for Various Nucleic Acid Purification
Methods
- Table 11: Median and Average Price Per Prep for Nucleic Acid Purification
Products
- Table 11A: Change in Median and Average Price Per Prep for Nucleic Acid
Purification Products
- Table 12: Estimated 2012 Global Market Size for Nucleic Acid Purification
Products by Category
- Table 13: Respondents' Primary Supplier for Nucleic Acid Purification
Products
- Table 14: Respondents' Primary Supplier for Gel Extraction Products by
Market Segment
- Table 15: Respondents' Primary Supplier for Post-reaction Cleanup Products
by Market Segment
- Table 16: Market Share Leaders for Gel Extraction and Post-reaction
Cleanup Products
- Table 17: Respondents' Primary Supplier for Plasmid DNA Miniprep
Purification Products by Market Segment
- Table 18: Respondents' Primary Supplier for Plasmid DNA Midiprep
Purification Products by Market Segment
- Table 19: Respondents' Primary Supplier for Plasmid DNA Maxiprep
Purification Products by Market Segment
- Table 20: Market Share Leaders for Plasmid DNA Purification Products
- Table 21: Respondents' Primary Supplier for Purifying Genomic DNA from
Cells or Tissue by Market Segment
- Table 22: Respondents' Primary Supplier for Purifying Genomic DNA from
Whole Blood by Market Segment
- Table 23: Respondents' Primary Supplier for Purifying Genomic DNA from
FFPE Tissue Products by Market Segment
- Table 24: Market Share Leaders for Genomic DNA Purification Products
- Table 25: Respondents' Primary Supplier for Purifying Total RNA from Cells
or Tissue by Market Segment
- Table 26: Respondents' Primary Supplier for Purifying Total RNA from Whole
Blood by Market Segment Tissue by Market Segment
- Table 28: Respondents' Primary Supplier for Purifying mRNA by Market
Segment
- Table 29: Respondents' Primary Supplier for Purifying microRNA by Market
Segment
- Table 30: Market Share Leaders for RNA Purification Products
- Table 31: Percentage of Respondents Satisfied with Various Nucleic Acid
Purification Product Categories and Reasons for Dissatisfaction
- Table 32: Percentage of Respondents Satisfied with Nucleic Acid
Purification Product Categories - Comparison to 2009 Nucleic Acid Purification
Dashboard
- Table 33: Most Important Features of Products for Nucleic Acid
Purification - Comparison to 2009 Nucleic Acid Purification Dashboard
