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市場調查報告書
奈米科技對投藥及藥物開發的影響
Drug Delivery - Drug Discovery Package
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本報告已在2011年07月19日停止出版。
奈米科技由於是一項極為細小單位的技術，可以順利投藥在人體極細微的地方，也可以輕易穿透藥品的細胞壁，因此今後其重要性也是可以預料得到的。另一方面，當今開發一項新的醫療藥品要花上 7 ∼ 10 年的時間及 8 億美金以上的成本。未來在實現低成本•短期間並且兼具安全性的藥物開發上，一般相信奈米科技將是一項關鍵的因素。
專門調查與分析奈米科技在通信、IT、半導體、生物醫學及能源領域的影響的美國市調公司 NanoMarkets （總公司: 維吉尼亞州），調查與分析奈米投藥及藥物開發市場的商機，並有系統地出版報告書組合“Drug Delivery - Drug Discovery Package”。
此報告書組合是由以下報告書所構成。 - 第 1 章 奈米基礎的投藥技術與製品
- 第 2 章 商品化過程
- 第 3 章 奈米 DDS 的各地分析
- 第 4 章 預測
- 第 1 章 序論
- 第 2 章 促進因素、阻礙因素、課題、規範課題與政府支援政策
- 第 3 章 奈米科技在藥物開發上的應用方式
- 第 4 章 市場參與企業
- 第 5 章 有關奈米藥物開發的8年內預測
Summary
This report examines the business opportunities that are being created by nano-engineered solutions for the drug delivery market. According to one source, approximately $65 billion in drug revenues every year are accounted for by pharmaceuticals with poor bio-availability which far too often results in higher patient costs and inefficient treatment but also, more importantly, increased risks of toxicity or even death. Because nanotechnology focuses on the very small it is uniquely suited to creating systems that can better deliver drugs to tiny areas within the body. Nano-enabled drug delivery also makes it possible for drugs to permeate through cell walls, which is of critical importance to the expected growth of genetic medicine over the next few years.
Summary
Pharmaceutical and biotechnology companies are under immense pressures to produce a steady stream of innovative, well-differentiated drugs at reduced costs. Currently it takes an estimated 7-10 years to develop and market a drug at a cost that exceeds $800 million. In simple terms, drug discovery requires the identification of a disease, knowledge of the disease mechanism and identification of a target (point of intervention). The human genome project is expected to identify approximately 100,000 targets that will require evaluation against many compound libraries to compare gene sequences and structure. This represents a very time-consuming process and a major bottleneck in the drug discovery process as millions of compounds can be screened for each target. Novel discovery and validation technologies can expand the hit rate for promising compounds in the pipeline, and expedite their progress through to market. The introduction of microarrays and lab-on-a-chip technologies has already revolutionized the drug
discovery process. Where once it took the effort of a single chemist to view anything from one to 12 gene variations at a time, microarrays can view thousands in the same time frame. Now, nanotechnology promises to exponentially increase even the volume of microarrays by working at a level far smaller than conventional microarrays and according to one source the pharmaceutical market will represent approximately $180 billion of the forecasted $1 trillion nanotech industry.
The Impact of Nanotechnology in Drug Delivery: Global Developments, Market Analysis and Future Prospects
Table of Contents
- Executive Summary
- Chapter One: Introduction
- Chapter Two: Nanotechnology-Based Drug Delivery Technologies
- Chapter Three: The Commercialization Process -Factors in Taking a Nano-Enabled Drug Delivery System to Market
- Chapter Four: Geographic Considerations for Nano-Enabled Drug Delivery Systems
- Chapter Five: Eight-Year Market Forecasts
- Appendix A: List of Acronyms and Abbreviations Used in This Report
- Appendix B: Contact Information for Key Firms in Nano-Enabled Drug Delivery
- About the Author
The Impact of Nanotechnology in Drug Discovery: Global Developments, Market Analysis and Future Prospects
Table of Contents
- Executive Summary
- Chapter One: Introduction
- Chapter Two: Drivers, Restraints, Challenges, Regulatory Issues and Government Funding Policies
- Chapter Three: Applications of Nanotechnology in Drug Discovery
- Chapter Four: The Players
- Chapter Five: Eight-Year Projections of Nano-enabled Drug Discovery Revenues
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