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市場調查報告書
肥胖症的臨床管理:全球的產品、技術、以及市場(2011年∼2019年)
Products, Technologies and Markets Worldwide for the Clinical Management of Obesity, 2011-2019
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肥胖症的臨床管理:全球的產品、技術、以及市場(2011年∼2019年) 是由出版商MedMarket Diligence在2011年02月所出版的。
這份英文市場調查報告書包含302 Pages 價格從美金2950起跳。
本報告,彙整肥胖症臨床管理上的技術動向、產品概要,並加上現在的肥胖病患人口、2011年至2019年的市場發展預測、以及主要企業的市佔率,由下列摘要形式闡述。
報告摘要
第1章 肥胖症的臨床背景
- 肥胖症的臨床診斷
- 肥胖的影響
- 能量平衡的代謝管道
- 體重過重與肥胖的共病症
- 全球的肥胖症罹患率與病患數
第2章 肥胖症的影響
- 肥胖與共病症的治療成本
- 對商業的影響
- 預防與減重的立法
第3章 針對體重過重與肥胖治療的臨床方式
- 行為改變與生活方式改變所扮演的角色
- 非處方減重產品
- 肥胖症的投藥治療:過去、現在、未來的治療藥物
- 肥胖症的非投藥治療
第4章 市場評價
- 影響市場預測的近期發展
- 全球的肥胖治療市場
- 主要企業的市佔率
- 南北美的肥胖治療市場
- 歐洲的肥胖治療市場
- 亞太地區的肥胖治療市場
- 其他區域的肥胖治療市場
- 全球肥胖治療市場的策略
第5章 企業檔案資料
第6章 臨床實驗
附錄:企業名錄
Abstract
This report is a detailed market and technology assessment and forecast of the
products and technologies in the clinical management of obesity (bariatrics).
The report describes the current and projected patient population in obesity,
detailing their incidence worldwide, with available incidence by country for
the U.S., major European countries, major countries in Asia/Pacific (including
Japan, China, India and Australia), the clinical practices in their management
to encompass surgical approaches, medical supervised severely restricted
diets, drug therapies, OTC treatments, biopharmaceuticals, non-pharmacologic
approaches and weight maintenance approaches. The report describes clinical
trends in the management of the obese. The report details the products on the
market and the status of those in development for bariatric surgery, drug
therapy, gastric stimulation devices, brain stimulation devices, combination
therapies and genetic therapy and other therapies under development, and will
provide current and worldwide market forecasts (2009-2019) separately for
pharmaceuticals (with separate segment forecast data for satiety,
malabsorption, appetite suppression and combination drugs) and devices (with
separate segment forecast data for stomach restriction artificial fullness,
malabsorption, gastric emptying and appetite suppression), with current (2009)
market shares of the leading competitors in each segment. The report profiles
the 45 leading competitors, detailing current and potential position in the
market, their products and their market strengths and likelihood of future
success.
Methodology
MedMarket Diligence Reports are produced through primary and secondary
research. Data is gathered from published sources on products and technologies
on the market and under development. Clinicians and industry representatives
are interviewed for their knowledge and insights on product development,
market development, clinical practice and trends associated with the evolving
use of technologies. Secondary data is used to corroborate and support
assessments and projections. Reports are written and researched by industry
insiders, whose familiarity with the companies, industry dynamics and other
marketplace specifics facilitate the research process and ensure high quality
and thorough reports.
Report Statistics
- 304 pages
- 79 Exhibits
- 46 Company Profiles
Table of Contents
EXECUTIVE SUMMARY
SECTION 1: CLINICAL BACKGROUND OF OBESITY
- 1.1 Clinical Diagnosis of Obesity
- 1.1.1 Body Mass Index Scale
- 1.1.2 Measuring BMI vs. Measuring Adiposity
- 1.1.3 Classification of Obesity
- 1.1.4 Overweight, Obesity, Morbid Obesity, Super Obesity
- 1.1.5 Genetic Testing for Obesity
- 1.2 Obesogenic Influences
- 1.2.1 Dietary Changes Over the Last Twenty Years
- 1.2.2 Sedentary Lifestyles
- 1.2.3 Ongoing Research into Causes
- 1.3 Metabolic Pathways of Energy Homeostasis
- 1.3.1 Role of the Hypothalamus
- 1.3.2 Role of the Stomach
- 1.3.3 Role of the Small Intestine
- 1.3.4 Role of the Pancreas
- 1.3.5 Role of Adipose Tissue, An Endocrine Organ
- 1.3.6 Other Peptides
- 1.3.7 Obesity as Survival Mechanism
- 1.4 Co-Morbidities of Overweight and Obesity
- 1.4.1 Metabolic Syndrome
- 1.4.2 Effects of Obesity on Immune Function
- 1.4.3 Racial Differences in Co-morbidities
- 1.4.4 Type 2 Diabetes and Insulin Resistance
- 1.4.5 Hypertension
- 1.4.6 Dyslipidemia
- 1.4.7 Depression
- 1.4.8 Osteoarthritis
- 1.4.9 Asthma
- 1.4.10 Sleep apnea
- 1.4.11 Obesity and Cancer
- 1.5 Global Incidence and Prevalence of Obesity
- 1.5.1 By Geographic Region
- 1.5.1.1 USA, Canada, Mexico, Brazil
- 1.5.1.2 European Union
- 1.5.1.3 Asia-Pacific
- 1.5.2 By Age Group
- 1.5.2.1 Incidence and Prevalence among Children
- 1.5.2.2 Incidence and Prevalence among Elderly
- 1.5.3 Incidence and Prevalence of Morbid Obesity
SECTION 2: THE IMPACT OF OBESITY
- 2.1 Costs Related to Treating Obesity and Co-Morbidities
- 2.1.1 Current Healthcare Expenses
- 2.1.1.1 Spending in the USA
- 2.1.1.2 Outside of the U.S., Spending Also Rising
- 2.1.2 The Looming Wave of Type 2 Diabetes
- 2.2 Impact on Businesses
- 2.2.1 Increased Health and Life Insurance Costs
- 2.2.2 Increased Costs Shouldered by Employers
- 2.2.3 Debate: Pay Employees to Lose Weight?
- 2.3 Legislating Prevention and Weight Loss
- 2.3.1 Healthcare Reform and Obesity
- 2.3.2 Changing Society
- 2.3.3 Pressure on the Food Industry
SECTION 3: CLINICAL APPROACHES TO THE TREATMENT OF OVERWEIGHT AND OBESITY
- 3.1 Role of Behavior Modification and Lifestyle Changes
- 3.1.1 Behavior Modification with Pharmacotherapies
- 3.1.2 Specialists' Use of Pharmaceuticals
- 3.1.3 Medically Supervised Low Calorie and Very Low Calorie Diets (LCDs
and VLCDs)
- 3.1.4 Why Diets Usually Fail
- 3.1.5 The Diogenes Study' s Dietary Recommendations
- 3.2 Non Prescription Weight Loss Products
- 3.3 Pharmaceutical Treatment of Obesity: Past, Present and Future Drugs
- 3.3.1 The US FDA' s Guidance for Industry Developing Products for Weight
Management
- 3.3.2 Definition of Satiety vs. Appetite Suppression
- 3.3.3 Definition of Combination Drugs
- 3.3.4 The Bloom is Off the Rose: Promising Drugs Which Have Failed, and
Why
- 3.3.4.1 Phentermine/Fenfluramine Combination
- 3.3.4.2 Abbott' s Meridia (Sibutramine)
- 3.3.4.3 Vivus' Qnexa: Out for Good?
- 3.3.4.4 Arena' s Lorqess: Not out of the picture yet
- 3.3.5 Prescription Drugs Currently on the Market
- 3.3.5.1 Appetite Suppression Drugs
- 3.3.5.2 Malabsorption Drugs
- 3.3.5.3 Satiety Drugs
- 3.3.5.4 Combination Drugs
- 3.3.6 Areas of Pharmaceutical Research
- 3.3.6.1 Melanocortin Receptor System
- 3.3.6.2 Cannabinoid Receptor Antagonists
- 3.3.6.3 GLP-1 Analogs
- 3.3.6.4 Methionine Aminopeptidase 2 (MetAP2) Inhibitor
- 3.3.6.5 Appetite Suppression Drugs
- 3.3.6.6 Malabsorption Drugs
- 3.3.6.7 Satiety Drugs
- 3.3.6.8 Combination Drugs
- 3.3.7 Safety: The Major Diet Drug Hurdle
- 3.4 Non- Pharmaceutical Options for Treating Obesity
- 3.4.1 Metabolic/Bariatric Surgery
- 3.4.1.1 Buchwald and Oien Research, 2009
- 3.4.1.2 Vertical Banded Gastroplasty
- 3.4.1.3 Roux-en-Y Surgery
- 3.4.1.4 Sleeve Gastrectomy
- 3.4.1.5 Biliopancreatic Diversion with Duodenal Switch
- 3.4.1.6 Jejuno-ileal Bypass: An Obsolete Procedure
- 3.4.2 Devices to Treat Obesity
- 3.4.2.1 Restrictive Devices
- 3.4.2.2 Artificial Fullness Devices
- 3.4.2.3 Malabsorption Devices
- 3.4.2.4 Devices to Control Gastric Emptying
- 3.4.2.5 Appetite Suppressive Devices
- 3.4.2.6 Gastric Electrical Stimulation
SECTION 4: MARKET ASSESSMENT
- 4.1 Recent Developments Impacting Market Forecasts
- 4.2 Anticipated Developments Underlying the Market Forecast
- 4.3 Global Market for Obesity Treatments
- 4.3.1 Pharmaceuticals
- 4.3.2 Devices
- 4.4 Market Shares of Leading Companies
- 4.4.1 Leading Pharmaceutical Companies
- 4.4.2 Leading Device Companies
- 4.5 Americas Market for the Treatment of Obesity
- 4.5.1 USA
- 4.5.2 Canada
- 4.5.3 Mexico
- 4.5.4 Brazil
- 4.6 European Market for the Treatment of Obesity
- 4.6.1 United Kingdom
- 4.6.2 Germany
- 4.6.3 France
- 4.6.4 Spain
- 4.6.5 Italy
- 4.6.6 Rest of Europe
- 4.7 Asia-Pacific Markets for the Treatment of Obesity
- 4.7.1 Japan
- 4.7.2 China
- 4.7.3 India
- 4.7.4 Australia
- 4.8 ROW Markets for the Treatment of Obesity
- 4.9 Strategies in the Global Obesity Market
- 4.9.1 Market Drivers
- 4.9.1.1 Significant Unmet Needs
- 4.9.1.2 The Need for a Variety of Treatment Options
- 4.9.1.3 Device Opportunity Grows Due to Lack of Drugs
- 4.9.1.4 Healthcare Reform
- 4.9.1.5 Treating Obesity to Avoid Costly Co-Morbidities
- 4.9.2 Market Restraints
- 4.9.2.1 Intense Complexity of the Metabolic Regulatory System
- 4.9.2.2 Time, Costs, Risks Involved in Developing a More Efficacious
Drug
- 4.9.2.3 Tightening of Safety Requirements for Obesity Drugs
- 4.9.2.4 Data Showing Lack of Sustainable Weight Loss with Gastric
Banding
- 4.9.2.5 Lack of Reimbursement
- 4.9.3 Strategies for Market Success
SECTION 5: COMPANY PROFILES
- 5.1 7TM Pharma
- 5.2 Abbott Laboratories
- 5.3 Allergan
- 5.4 Amylin Pharmaceuticals
- 5.5 Arena Pharmaceuticals
- 5.6 AstraZeneca
- 5.7 BAROnova Therapeutics
- 5.8 BaroSense
- 5.9 BFKW, LLC (c/o Legacy Capital Advisors, LLC)
- 5.10 Covidien
- 5.11 CR Bard, Inc.
- 5.12 Crospon, Inc.
- 5.13 Eli Lilly & Company
- 5.14 EndoGastric Solutions
- 5.15 EndoSphere
- 5.16 EnteroMedics, Inc.
- 5.17 Ethicon Endo-Surgery, Inc. (JNJ)
- 5.18 Gelesis, Inc.
- 5.19 GI Dynamics
- 5.20 GlaxoSmithKline
- 5.21 Helioscopie
- 5.22 Interleukin Genetics
- 5.23 IntraPace
- 5.24 Laboratoire Endalis
- 5.25 Merck
- 5.26 MetaCure
- 5.27 Nestle Healthcare Nutrition
- 5.28 NeuroSearch A/S
- 5.29 Novo Nordisk
- 5.30 Orexigen Therapeutics, Inc.
- 5.31 Pfizer, Inc.
- 5.32 ReShape Medical
- 5.33 Rhythm Pharmaceuticals
- 5.34 SafeStitch Medical, Inc.
- 5.35 Sanofi-Aventis
- 5.36 Satiety, Inc.
- 5.37 Scientific Intake, LLC
- 5.38 Shionogi & Co., Ltd.
- 5.39 Silhouette Medical, Inc.
- 5.40 Spatz FGIA, Inc.
- 5.41 Surface Logix, Inc.
- 5.42 USGI Medical
- 5.43 ValenTx, Inc.
- 5.44 Verva Pharmaceuticals Ltd.
- 5.45 Vivus, Inc.
- 5.46 Zafgen, Inc.
SECTION 6: CLINICAL TRIALS
APPENDIX: COMPANY DIRECTORY
List of Exhibits
- Exhibit ES-1: Estimated Overweight & Obesity (BMI > 25 kg/m2) Prevalence,
Males, Aged 15+, 2010
- Exhibit ES-2: Past and Projected Future Overweight Rates in Selected
O.E.C.D. Countries
- Exhibit ES-3: Global Market for Treatment of Obesity, 2009-2019 (USD
millions)
- Exhibit ES-4: Regional Percent Revenue Shares, 2009
- Exhibit ES-5: Manufacturer Percent Revenue Shares, Global Obesity Market,
2009
- Exhibit 1-1: Calculation of Body Mass Index (BMI)
- Exhibit 1-2: Proposed WHO Classification of BMI in Adult Asians
- Exhibit 1-3: The International BMI Classification of Adult Underweight,
Overweight and Obesity According to the World Health Organization (WHO)
- Exhibit 1-4: The Human Gastrointestinal Tract
- Exhibit 1-5: From Chronic Energy Imbalance to Co-Morbidities
- Exhibit 1-6: Relative Risk of Mortality by BMI in US Men
- Exhibit 1-7: Relative Risk of Mortality by BMI in US Women
- Exhibit 1-8: World Incidence and Prevalence for Cancers Associated with
Obesity
- Exhibit 1-9: AICR Estimated Cases Per Year of Cancers Linked to Excss Body
Fat
- Exhibit 1-10: Populations and Rates of Obesity of Selected Countries, 2009
- Exhibit 1-11: Estimated Overweight & Obesity (BMI > 25 kg/m2) Prevalence,
Males, Aged 15+, 2010
- Exhibit 1-12: Past and Projected Future Overweight Rates in Selected
O.E.C.D. Countries
- Exhibit 1-13: Percent of Adults Who are Overweight/Obese, by Country, 2010
- Exhibit 1-14: USA Obesity Prevalence by State, 2004.
- Exhibit 1-15: USA Obesity Prevalence by State, 2009.
- Exhibit 1-16: Prevalence of Obesity in Canada for 1978-2005 (Measured
Values)
- Exhibit 1-17: Prevalence of Overweight and Obesity in Women and Men in
Mexico from a Nationally Representative Sample and a Sample of Low-Income
Rural Mexicans
- Exhibit 1-18: WHO Prevalence of Obesity by Sex, Adults Aged 15 and Over,
Latest Available Year, Europe
- Exhibit 1-19: States of India ranked by percentage of overweight or obese
(2006)
- Exhibit 1-20: Percent of Children in Select Age Groups and Countries Who
are Overweight (Including Obese), 2010
- Exhibit 3-1: FDA List of Tainted Weight Loss Products, March 2009
- Exhibit 3-2: Companies with Obesity Pharmaceuticals on Market or in
Development, 2010
- Exhibit 3-3: Number Of Bariatric Surgeons and Bariatric Surgery
Operations, 2008
- Exhibit 3-4: Global Trend in Metabolic/Bariatric Surgery, 2003-2013
- Exhibit 3-5: Global Trends in Metabolic/Bariatric Surgery, 2003-2013
- Exhibit 3-6: Regional Trend in Metabolic/Bariatric Surgery, USA/Canada,
2003-2008
- Exhibit 3-7: USA/Canada Trends in Metabolic/Bariatric Surgery, 2003-2013
- Exhibit 3-8: Regional Trends in Metabolic/Bariatric Surgery, Europe,
2003-2013
- Exhibit 3-9: European Trends in Metabolic/Bariatric Surgery, 2003-2013
- Exhibit 3-10: Regional Trends in Metabolic/Bariatric Surgery,
Asia/Pacific, 2003-2013
- Exhibit 3-11: Regional Trends in Metabolic/Bariatric Surgery,
Asia/Pacific, 2003-2013
- Exhibit 3-12: Regional Trend in Metabolic/Bariatric Surgery, Rest of
World, 2003-2013
- Exhibit 3-13: Regional Trends in Metabolic/Bariatric Surgery, Rest of
World, 2003-2013
- Exhibit 3-14: Companies with Obesity Devices on Market or in Development,
2010
- Exhibit 4-1: Global Market for Treatment of Obesity, 2009-2019 (USD
millions)
- Exhibit 4-2: Global Market for Treatment of Obesity, 2009-2019 (USD
millions)
- Exhibit 4-3: Total Modality Market Shares by Percent Revenues, 2009
- Exhibit 4-4: Total Modality Market Shares by Percent Revenue, 2019
- Exhibit 4-5: Global Markets for Pharmaceutical Treatment of Obesity,
2009-2019 (USD Millions)
- Exhibit 4-6: Global Markets for Pharmaceutical Treatment of Obesity,
2009-2019 (USD Millions)
- Exhibit 4-7: Global Market for Device Treatment of Obesity, 2009-2019,
(USD Millions)
- Exhibit 4-8: Global Market for Medical Device Treatment of Obesity,
2009-2019 (USD Millions)
- Exhibit 4-9: Percent Revenue Shares, Global Obesity Market, 2009
- Exhibit 4-10: Percent Revenue Shares, Global Anti-Obesity Drug Market, 2009
- Exhibit 4-11: Percent Revenue Shares, Global (Off-Label) Satiety Drug
Market, 2009
- Exhibit 4-12: Percent Revenue Shares, Global Pharmaceutical Appetite
Suppression Market, 2009
- Exhibit 4-13: Percent Revenue Shares, Global Anti-Obesity Devices Market,
2009
- Exhibit 4-14: Percent Revenue Shares, Global Restrictive Devices Market,
2009
- Exhibit 4-15: Percent Revenue Shares, Global Artificial Fullness Devices
Market, 2009
- Exhibit 4-16: Percent Revenue Shares, Global Appetite Suppression Devices
Market, 2009
- Exhibit 4-17: Americas Market for Treatment of Obesity, 2009-2019
- Exhibit 4-18: Americas Market for Treatment of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-19: USA Market for Treatments of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-20: Canada Market for Treatments of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-21: Mexico Market for Treatments of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-22: Brazil Market for Treatments of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-23: European Market for Treatment of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-24: EU Obesity Percent Revenue Market Shares by Country, 2009
- Exhibit 4-25: EU Obesity Percent Revenue Market Shares by Country, 2019
- Exhibit 4-26: European Market for Treatment of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-27: UK Market for Treatment of Obesity, 2009-2019 (USD Millions)
- Exhibit 4-28: Trends in Gastric Bypass vs. Gastric Banding, England,
2000-2007
- Exhibit 4-29: Germany Market for Treatment of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-30: France Market for Treatment of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-31: Spain Market for Treatment of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-32: Italy Market for Treatment of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-33: Rest of Europe Market for Treatment of Obesity, 2009-2019
(USD Millions)
- Exhibit 4-34: Asia-Pacific Market for Treatment of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-35: Asia-Pacific Market for Treatment of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-36: Japan Market for Treatment of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-37: China Market for Treatment of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-38: India Market for Treatment of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-39: Australia Market for Treatment of Obesity, 2009-2019 (USD
Millions)
- Exhibit 4-40: Rest of World Market for Treatment of Obesity, 2009-2019
(USD Millions)
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