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市場調查報告書

治療層級概要:微生物的新虛擬形象 - 全球增加威脅的超級錯誤

New Avatars of Microbes Super Bugs a Growing Threat Worldwide!

出版商 MP Advisors 商品編碼 296609
出版日期 內容資訊 英文 13 Pages
商品交期: 最快1-2個工作天內
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治療層級概要:微生物的新虛擬形象 - 全球增加威脅的超級錯誤 New Avatars of Microbes Super Bugs a Growing Threat Worldwide!
出版日期: 2014年02月25日 內容資訊: 英文 13 Pages
簡介

對感染疾病治療的新的方法成為迫切需要。帶來著抗生素的濫用使之加速抗生素抗性(AMR),出示關乎生命的問題的「超級錯誤」的全世界的出現。

本報告提供感染疾病治療的新方法的必要性相關研究,AMR(抗生素抗性)的演進與世界性播種,感染疾病治療新藥的開發採用的標靶藥物的平台,法規當局的措施,發展中國家的病原菌、藥物抗性趨勢,及診斷、預防的方法所扮演的角色等相關調查,為您概述為以下內容。

簡介

  • 問題顯示多少應該憂慮的層級?
  • 微生物的演進超越創新!
  • 「壞蟲」的攔車旅行及全球旅遊

重大的情形的未滿足需求

  • 革蘭氏陰性菌感染的治療藥物不足
  • 碳青霉烯類抗性腸內細菌(CRE)
  • CRE的演進
  • 錯誤的擴散

現在必要的事 - 新標靶藥物=新抗生素級

  • 感染疾病治療、抵抗用新藥的開發採用的新標靶藥物的平台
  • 中期、後期臨床開發階段的主要藥的平台

AMR相關的驚人事實 - CDC的警告

法規團體的行動:醫藥品開發、威脅認識的加速

  • 美國
  • 歐洲
目錄
Product Code: TC14022403

Novel approaches to treat infection is growing as the need is urgent! Misuse/overuse of antibiotics accelerated antimicrobial resistance (AMR) and has resulted in the emergence of “super bugs” which are posing life threatening challenges world wide. Many of the advances in medical treatment like cancer therapy; organ transplants etc. would go waste if the ability to fight infections during the treatment were not available. If that fails, the gains made in life-improving modern medical advantages will be lost creating a situation of - “one step forward two step back”. Novel approaches are immediately required to combat these “super infections” warranting need for new classes of antibiotics and other preventive/therapeutic approaches.

In this report We discuss -

  • The evolution and global dissemination of AMR
  • Unmet need in the critical setting esp. Gram Negative infections and CRE.
  • Pipeline of novel targets being used to develop new drugs to treat infections and resistance.
  • Pipeline of select drugs in mid and late clinical stage of development
  • Alarming Facts about AMR
  • Steps being taken by the regulatory authorities WW to address the issue and encourage novel therapeutics in this therapy area.
  • Developing Countries- /ROW -- Trends in pathogens and resistance
  • Role of diagnostics and preventive approach.

Table of Contents

Introduction - Evolution and global dissemination of Anti Micorbial Resistance (AMR)

  • How has the Problem Manifested to Such an Alarming Level?
  • Microbial Evolution has Outpaced Innovation!
  • Hitch Hiking and Globe Trotting by “Bad Bugs”

Unmet need in the critical setting

  • Running Out of Drugs to Treat Serious Gram-Negative Infections
  • Carbapenem-resistant Enterobacteriaceae (CREs)
  • Evolution of CRE
  • Spreading the Bug

Need of the Hour- New Targets= New Antibiotic Class

  • Pipeline of novel targets being used to develop new drugs to treat infections and resistance.
  • Pipeline of select drugs in mid and late clinical stage of development

Alarming Facts about AMR - CDC Alerts

Action by Regulatory Bodies - to Accelerate Drug development and Threat Awareness

US

  • The GAIN Act
  • Breakthrough Therapies Designation

Europe

  • Draft guidance “Expedited Programs for Serious Conditions--Drugs and Biologics”
  • Strategic Research Agenda
    Developing Countries- /ROW -- Trends in pathogens and resistance Role of diagnostics and preventive approach
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