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市場調查報告書

美國的乳癌治療市場機會分析

US Breast Cancer Therapy Market Opportunity Analysis

出版商 KuicK Research 商品編碼 335071
出版日期 內容資訊 英文 700 Pages
商品交期: 最快1-2個工作天內
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美國的乳癌治療市場機會分析 US Breast Cancer Therapy Market Opportunity Analysis
出版日期: 2015年07月09日 內容資訊: 英文 700 Pages
簡介

乳癌,是影響乳房組織的惡性腫瘤,其發病率在全世界增加。還有是美國女性尤其罹患率和死亡率高,高頻率的癌症。

本報告提供美國的乳癌治療市場相關調查分析、發病率和罹患率、市場概要、臨床實驗平台、主要藥、上市藥、專利分析等相關的系統性資訊。

第1章 美國的乳癌發病率和罹患率

第2章 美國的乳癌治療市場概要

  • 目前市場方案
  • 美國的乳癌治療藥的開發平台概要

第3章 美國的乳癌治療市場趨勢

  • 有利的市場參數
  • 商品化的課題

第4章 美國的乳癌治療市場未來發展預測

第5章 乳癌治療藥的機制

第6章 美國的乳癌治療藥的臨床實驗平台:各企業、各階段

  • 研究
  • 前臨床
  • 臨床
  • 第0階段
  • 第一階段
  • 第一/二階段
  • 第二階段
  • 第二/三階段
  • 第三階段
  • 認證前
  • 已認證

第7章 美國的已上市乳癌治療藥臨床考察和專利分析:各企業

第8章 美國的臨床實驗平台的中止、中斷的乳癌治療藥

  • 沒有開發報告
  • 中止
  • 來自市場的撤退
  • 中斷

第9章 競爭情形

  • AbbVie
  • Agilent Technologies
  • ARIAD Pharmaceuticals
  • AstraZeneca
  • Bayer
  • Biodesix
  • BioMarin Pharmaceutical
  • Boehringer Ingelheim
  • Bristol Mayer Squibb
  • Celgene Corporation
  • Dako A/S
  • Debiopharm
  • Dyax
  • Eisai
  • Eli Lily
  • Exelixis
  • GalaxoSmithKline
  • Incyte Corporation
  • Ligand Pharmaceuticals
  • Merck
  • Navidea Biopharmaceuticals
  • Nektar Therapeutics
  • Novartis
  • Onyx pharmaceuticals
  • Pfizer
  • Roche
  • Sanofi
  • Sun Pharmaceuticals

圖表

目錄

Breast cancer is a type of malignancy that affects breast tissue and its incidences are increasing across the globe. It is also one of the most common cancers in American women which cause high morbidity and mortality rates. It affects both gender but most of the cases have been found to be related to females as compared to males. Data shows that the numbers of breast cancer incidences and death has remained stagnant with slight change in each year as compared to previous years. It also reflects that much change has not been observed despite use of better breast cancer therapeutics. So, it has become imperative to identify the solutions with which breast cancer could be treated effectively. Pharmaceutical companies are investing significantly in this segment to formulate effective strategy to prevent future breast cancer incidences.

Several breast cancer therapeutics have been introduced for providing higher safety and efficacy levels. These therapies belong to wide range of categories out of which some of them have achieved blockbuster status. Monoclonal antibodies (mAbs) are one of most widely used therapeutics owing to high safety, efficacy and specificity along with minimized side effects. Breast cancer market in US took a major leap when Genentech's monoclonal antibody (mAb) Herceptin got FDA's approval in 1998. Other big pharmaceutical companies soon followed the lead and introduced breast cancer monoclonal antibodies in US. Presently, the high cost of these medicines marketed makes it difficult for breast cancer patients to introduce them in their regular therapeutic regime. It is expected that in the near future, these companies will launch cost effective breast cancer medicines. Many pharmaceutical companies are also exploring the different areas for the development of efficient breast cancer therapeutics.

US Breast cancer market is dominated by monoclonal antibodies due to superior pharmacological effects and availability of large number of products in this segment. Herceptin (Trastuzumab monoclonal antibody) is commonly prescribed breast cancer medicine. Roche developed Pertuzumab monoclonal antibody after the block buster success of Herceptin (Trastuzumab monoclonal antibody). The inhibition of HER2 is its basic mechanism to prevent the growth and proliferation of breast cancer in women. It was approved in 2012 by the FDA for the treatment of or late-stage metastatic HER2-positive breast cancer patients.

Various pharmaceutical companies are expected to introduce novel breast cancer medicines and technologies in future. Most of them are at different stages of clinical trials and would be introduced in coming years. However, the cost of pharmacologically superior therapeutics is quite high due to which limited breast cancer patients include them in their therapeutic regime. In future, the high cost breast cancer medicines will be replaced by affordable medicines due to advancements in technologies. Nanotechnology based breast cancer medicines are being developed whose introduction in US may take time. New molecular targets are also being investigated that would help in development of innovative medicines in coming years. These developments shows that US breast cancer market will increase as new products would be introduced. In this way, future of breast cancer therapeutics in US seems to be optimistic.

"US Breast Cancer Therapy Market Opportunity Analysis" Report Highlight:

  • US Breast Cancer Incidence & Prevalence
  • US Breast Cancer Therapy Market Overview
  • US Breast Cancer Drug Clinical Pipeline by Company & Phase
  • US Breast Cancer Drug Clinical Pipeline: 251 Drugs
  • Majority Drugs in Phase-II Trials: 73 Drugs
  • Marketed Breast Cancer Drugs in US: 32 Drugs
  • Breast Cancer Patent Analysis

Table of Contents

1. US Breast Cancer Incidence & Prevalence

2. US Breast Cancer Therapy Market Overview

  • 2.1 Current Market Scenario
  • 2.2 US Breast Cancer Drug Pipeline Overview

3. US Breast Cancer Therapy Market Dynamics

  • 3.1 Favorable Market Parameters
  • 3.2 Commercialization Challenges

4. US Breast Cancer Therapy Market Future Prospects

5. Mechanism of Breast Cancer Drugs

6. US Breast Cancer Drug Clinical Pipeline by Company & Phase

  • 6.1 Research
  • 6.2 Preclinical
  • 6.3 Clinical
  • 6.4 Phase-0
  • 6.5 Phase-I
  • 6.6 Phase-I/II
  • 6.7 Phase-II
  • 6.8 Phase-II/III
  • 6.9 Phase-III
  • 6.10 Preregistration
  • 6.11 Registered

7. Marketed Breast Cancer Drug Clinical Insight & Patent Analysis by Company in US

  • 7.1 Albumin-Bound Paclitaxel (Abraxane)
  • 7.2 Anastrozole (Arimidex®)
  • 7.3 Capecitabine (Xeloda®)
  • 7.4 Docetaxel (Taxotere®)
  • 7.5 Eribulin (Halaven®)
  • 7.6 Everolimus (Afinitor®)
  • 7.7 Exemestane (Aromasin®)
  • 7.8 Fluoxymesterone
  • 7.9 Fulvestrant (Faslodex®)
  • 7.10 Gadobutrol
  • 7.11 Gemcitabine (Gemzar®)
  • 7.12 Goserelin (Zoladex®)
  • 7.13 Ixabepilone (Ixempra®)
  • 7.14 Lapatinib (Tykerb®)
  • 7.15 Letrozole (Femara®)
  • 7.16 Paclitaxel (Taxol®)
  • 7.17 Palbociclib (Ibrance™)
  • 7.18 Pertuzumab (Omnitarg™)
  • 7.19 Pertuzumab Companion Diagnostic (HER2 FISH pharmDx)
  • 7.20 Pertuzumab Companion Diagnostic (HercepTest)
  • 7.21 Raloxifene (Evista®)
  • 7.22 Tamoxifen Oral Liquid (Soltamox®)
  • 7.23 Tc 99m Tilmanocept (Lymphoseek®)
  • 7.24 Technetium Tc 99m Sulfur Colloid Diagnostic Injection
  • 7.25 Temsirolimus (Fareston®)
  • 7.26 Trastuzumab (Herceptin®)
  • 7.27 Trastuzumab Companion Diagnostic (HER2 CISH pharmDx)
  • 7.28 Trastuzumab Companion Diagnostic (HER2 FISH pharmDx)
  • 7.29 Trastuzumab Companion Diagnostic (HercepTest)
  • 7.30 Trastuzumab Emtansine (Kadcyla®)
  • 7.31 Vinorelbine
  • 7.32 Vitamin B12 Fluorescent-Analogues (CobalaFluor Green™, CobalaFluor Red™)

8. Discontinued & Suspended Breast Cancer Drug in Clinical Pipeline in US

  • 8.1 No Development Reported
  • 8.2 Discontinued
  • 8.3 Preregistration-Submission Withdrawal
  • 8.4 Suspended

9. Competitive Landscape

  • 9.1 AbbVie
  • 9.2 Agilent Technologies
  • 9.3 ARIAD Pharmaceuticals
  • 9.4 AstraZeneca
  • 9.5 Bayer
  • 9.6 Biodesix
  • 9.7 BioMarin Pharmaceutical
  • 9.8 Boehringer Ingelheim
  • 9.9 Bristol Mayer Squibb
  • 9.10 Celgene Corporation
  • 9.11 Dako A/S
  • 9.12 Debiopharm
  • 9.13 Dyax
  • 9.14 Eisai
  • 9.15 Eli Lily
  • 9.16 Exelixis
  • 9.17 GalaxoSmithKline
  • 9.18 Incyte Corporation
  • 9.19 Ligand Pharmaceuticals
  • 9.20 Merck
  • 9.21 Navidea Biopharmaceuticals
  • 9.22 Nektar Therapeutics
  • 9.23 Novartis
  • 9.24 Onyx pharmaceuticals
  • 9.25 Pfizer
  • 9.26 Roche
  • 9.27 Sanofi
  • 9.28 Sun Pharmaceuticals

List of Figures

  • Figure 1-1: US -Estimated Breast Cancer Incidences, 2013-2015
  • Figure 1-2: US - Estimated Breast Cancer Deaths, 2013-2015
  • Figure 1-3: US -Estimated Incidences of Female Breast Cancer, 2013-2015
  • Figure 1-4: US -Estimated Female Breast Cancer Deaths, 2013-2015
  • Figure 1-5: US -Female Breast Cancer Incidence Compare to Others Cancers, 2015
  • Figure 1-6: US -Female Breast Cancer Deaths as compared to other Cancers, 2015
  • Figure 1-7: Diagnosis of Breast Cancer in Different Genders
  • Figure 1-8: US -Estimated Male Breast Cancer New Cases, 2013-2015
  • Figure 1-9: US -Estimate Male Breast Cancer Deaths, 2013-2015
  • Figure 2-1: US - Breast Cancer Drug in Clinical Pipeline by Phase (%), 2015
  • Figure 2-2: US -Breast Cancer Drug in Clinical Pipeline by Phase (Number), 2015
  • Figure 2-3: US -No Development Reported Breast Cancer Drug in Clinical Pipeline by Phase (%), 2015
  • Figure 2-4: US -No Development Reported Breast Cancer Drug in Clinical Pipeline by Phase (Number), 2015
  • Figure 2-5: US -Discontinued Breast Cancer Drug in Clinical Pipeline by Phase (%), 2015
  • Figure 2-6: US -Discontinued Breast Cancer Drug in Clinical Pipeline by Phase (Number), 2015
  • Figure 2-7: US - Suspended Breast Cancer Drug in Clinical Pipeline by Phase (%), 2015
  • Figure 2-8: US -Suspended Breast Cancer Drug in Clinical Pipeline by Phase (Number), 2015
  • Figure 3-1: US Breast Cancer Market Drivers
  • Figure 3-2: US Breast Cancer Therapy Market Commercialization Challenges
  • Figure 5-1: Type of Breast Cancer Treatment
  • Figure 5-2: Type of Breast Cancer Surgery
  • Figure 5-3: Mechanism of Trastuzumab
  • Figure 5-4: Mechanism of Docetaxel
  • Figure 5-5: Mechanism of Tamoxifen
  • Figure 9-1: AbbVie-Clinical Pipeline
  • Figure 9-2: ARIAD-Clinical Pipeline
  • Figure 9-3: Celgene Clinical Pipeline
  • Figure 9-4: Debiopharm-Clinical Pipeline
  • Figure 9-5: Eisai-Clinical Pipeline

List of Tables

  • Table 1-1: US -Estimated Number of New Cases for Female Breast Cancer by State, 2015
  • Table 1-2: US -Estimated Number of Deaths for Breast Cancer by State, 2015
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