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市場調查報告書

全球微型核糖核酸工具及服務市場

MicroRNA Tools and Services Market

出版商 Kalorama Information 商品編碼 357811
出版日期 內容資訊 英文 197 Pages
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全球微型核糖核酸工具及服務市場 MicroRNA Tools and Services Market
出版日期: 2016年05月03日 內容資訊: 英文 197 Pages
簡介

微型核糖核酸,是轉印後的基因表現的調整伴隨的小型非編碼分子之一,在許多組織,及細胞外的血清、血漿、唾液、尿等體液也能查出。

本報告提供全球微型核糖核酸工具及服務市場相關調查,工具,各類服務市場趨勢與收益預測,加入此市場的主要企業簡介等彙整資料。

第1章 摘要整理

第2章 簡介及miRNA的應用

  • miRNA的特性概要
  • miRNA關聯的應用
  • 疾病生物標記
  • 治療藥及標的

第3章 miRNA分析與機能分析技術

  • qRT-PCR
  • 混合化技術
  • miRNA功能分析工具

第4章 產業結構

  • 競爭趨勢
  • 進入障礙
  • 技術性技術訣竅、智慧財產權
  • 強的品牌知名度和專門性
  • 銷售、行銷能力/流通網
  • 競爭因素
  • 合併、收購
  • 市場趨勢
  • 市場收益
  • 阻礙市場成長的價格壓力
  • 市場收益與預測
  • 各工具市場收益與預測
    • qRT-PCR
    • 混合技術
    • 次世代定序
    • 功能的工具
  • 各類服務市場收益與預測
  • 競爭分析

第5章 企業簡介

圖表

目錄
Product Code: KLI5985878

MicroRNAs (miRNAs) are a class of small, non-coding RNA molecules involved in the regulation of gene expression at the post-transcriptional level. miRNAs have been detected in many types of tissues, as well as extracellularly in biofluids such as serum, plasma, saliva and urine. miRNAs are highly stable in samples such as FFPE, plasma and serum, rendering them particularly useful for the development of biomarkers and clinical diagnostics. MicroRNA Tools and Services Market examines the overall market for miRNA analysis tools and services.

The miRNA marketplace is dynamic, driven by constant innovation and translation of scientific knowledge to clinical applications. The report includes the following market information:

  • Estimated Market Breakdown by Tools and Services, 2015
  • Estimated Market Breakdown by Geographic Region, 2015 (North America, Europe, ROW)
  • Global Revenues and Forecast for the miRNA Tools and Services Market, 2013-2016 and 2020 (miRNA Analysis Tools, miRNA Services, Total market)
  • Global Revenues and Forecast for the miRNA Analysis Tools and Services Market by Geographic Region, 2013-2016 and 2020 (North America, Europe, Rest of World, Total market)
  • Global Revenues and Forecast for the miRNA Services Market by Type of Service, 2013-2016 and 2020 (Expression profiling /analysis, Functional analysis, Total services market)

The function of miRNAs is determined to a large extent by their expression levels. Currently, three major technologies are employed for profiling the expression of miRNA in various biological samples: amplification-based (quantitative reverse transcription PCR), hybridization-based (planar microarrays and bead-based arrays), and sequencing-based (next-generation sequencing) technologies. The report provides market information for these major technologies, including:

  • Global Revenues and Forecast for the qRT-PCR Segment of the miRNA Analysis Tools Market, 2013-2016 and 2020
  • Global Revenues and Forecast for the Hybridization-based Segment of the miRNA Analysis Tools Market, 2013-2016 and 2020
  • Global Revenues and Forecast for the NGS segment of the miRNA Analysis Tools Market, 2013-2016 and 2020
  • Global Revenues and Forecast for the Functional Tools Segment of the miRNA Analysis Tools Market, 2013-2016 and 2020

miRNAs show higher tissue and organ specificity than other biomolecules, and can also cross the blood-brain barrier, potentially constituting suitable biomarkers of brain health in various neurological diseases such as multiple sclerosis, Alzheimer's and Parkinson's disease. For therapeutic applications, the selective modulation of a single miRNA has the potential to regulate entire networks of involved genes and biological pathways, and to lead to the development of highly efficacious therapies in a multitude of diseases. As the alteration of normal miRNA expression levels contribute to the development of disease, current miRNA-based therapies in development aim to correct the imbalance associated with different diseases. The report discusses the applications of miRNA and notes:

  • Selected miRNAs Associated with Cancer (Non-small Cell Lung Cancer, Breast Cancer, Prostate Cancer, Colorectal Cancer, Gastric Cancer, Hepatocellular Carcinoma, Leukaemia, Lymphoma, Glioblastoma)
  • Selected Extracellular miRNAs Potential Biomarkers in Cardiovascular Disorders (Coronary Arterial Disease, Acute myocardial infarction, Heart Failure)
  • Selected miRNAs Associated with Neurological Disorders (Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, Epilepsy, Stroke)
  • Selected miRNA-based Diagnostic Assays, 2016
  • Selected miRNA-based Therapies in Clinical Development, 2016

MicroRNA Tools and Services Market provides profiles of the leading companies in the miRNA market, including:

  • Affymetrix
  • Agilent Technologies
  • Applied Biological Materials, Inc.
  • Asuragen, Inc.
  • Bioneer Corporation
  • Bio-Rad Laboratories, Inc.
  • Dharmacon
  • Exiqon
  • GeneCopoeia
  • GenoSensor Corporation
  • Hummingbird Diagnostics
  • HTG Molecular Diagnostics, Inc.
  • Illumina, Inc.
  • Integrated DNA Technologies
  • LC Sciences, LLC
  • Luminex Corporation
  • Miltenyi Biotec GmbH
  • Mirus Bio, LLC
  • NanoString Technologies
  • OriGene Technologies, Inc.
  • Phalanx Biotech Group
  • Promega Corporation
  • QIAGEN N.V.
  • Quanta BioSciences, Inc.
  • Regulus Therapeutics
  • F. Hoffmann-La Roche AG
  • Rosetta Genomics
  • Sigma-Aldrich Corporation
  • Thermo Fisher Scientific
  • Toray Industries
  • WaferGen Bio-systems, Inc.
  • Wako Pure Chemical Ind. Ltd.

Table of Contents

ONE: EXECUTIVE SUMMARY

  • Overview of miRNA and its Potential Applications
  • miRNA Profiling and Analysis Technologies
  • qRT-PCR
  • Hybridization-based Techniques
  • Next Generation Sequencing
  • Functional Tools
  • Industry Structure and Revenues

TWO: INTRODUCTION AND APPLICATIONS OF miRNA

  • Overview of miRNA Characteristics
  • Commercial Healthcare-Related Applications of miRNA
  • Disease Biomarkers
  • Therapeutic Agents and Targets

THREE: miRNA PROFILING AND FUNCTIONAL ANALYSIS TECHNOLOGIES

  • qRT-PCR
  • Overview
  • Advantages and Limitations of qRT-PCR
  • Challenges in miRNA profiling by qRT-PCR
  • Commercial qRT-PCR Products for miRNA Analysis
  • Selected qRT-PCR Array Platforms
  • Hybridization-based Techniques
  • Overview
  • Selected Commercial Hybridization-based Technologies
  • Next Generation Sequencing
  • Overview
  • Advantages of NGS in miRNA Analysis
  • Limitations of NGS in miRNA Analysis
  • NGS Sequencing Platforms
  • Commercial NGS Library Preparation Kits for miRNA Detection and Profiling
  • miRNA Functional Analysis Tools
  • Overview
  • miRNA Mimics
  • miRNA Inhibitors
  • Other Functional Tools - Target Site Blockers/Protectors

FOUR: INDUSTRY STRUCTURE

  • Tiers of Competition
  • Barriers to Entry
  • Technological Know-How/ Intellectual Property
  • Strong Brand Recognition and Expertise
  • Sales and Marketing Capabilities/ Distribution Networks
  • Competitive Factors
  • Notable Mergers and Acquisitions
  • ThermoFisher Scientific Acquired Life Technologies and Affymetrix
  • Merck KGA (Germany) Acquired Sigma-Aldrich
  • QIAGEN Offers to Buy Exiqon in March 2016
  • Market Trends
  • Intensified miRNA-related R&D Activity to Accelerate Market Growth
  • Increasing Development of miRNA-based Therapeutics and Diagnostics to Spur
  • Utilization of miRNA Technologies
  • Growing Utilization of Higher-Priced miRNA Analysis Technologies to Augment
  • Market Revenues
  • Availability of Research Funding from Various Entities to Stimulate Utilization of
  • miRNA Technologies
  • Limitations of Available Technologies to Restrict Utilization of miRNA Tools
  • and Services
  • Lack of Skilled Personnel to Limit Market Growth
  • Technological Know-How to Hinder Market Expansion
  • Pricing Pressures to Restrain Market Growth
  • Total Market Revenues and Forecast
  • Market Snapshot
  • Total Market Forecast
  • Market Revenues and Forecast by Type of Tool
  • qRT-PCR
  • Hybridization-based Techniques
  • NGS
  • Functional Tools
  • Market Revenues and Forecast by Type of Service
  • Competitive Analysis

FIVE: COMPANY PROFILES

  • Affymetrix
  • Agilent Technologies
  • Applied Biological Materials, Inc.
  • Asuragen, Inc.
  • Bioneer Corporation
  • Bio-Rad Laboratories, Inc.
  • Dharmacon
  • Exiqon
  • GeneCopoeia
  • GenoSensor Corporation
  • Hummingbird Diagnostics
  • HTG Molecular Diagnostics, Inc
  • Illumina, Inc.
  • Integrated DNA Technologies
  • LC Sciences, LLC
  • Luminex Corporation
  • Miltenyi Biotec GmbH
  • Mirus Bio, LLC
  • NanoString Technologies
  • OriGene Technologies, Inc.
  • Phalanx Biotech Group
  • Promega Corporation
  • QIAGEN N.V.
  • Quanta BioSciences, Inc.
  • Regulus Therapeutics
  • F. Hoffmann-La Roche AG
  • Rosetta Genomics
  • Sigma-Aldrich Corporation
  • Thermo Fisher Scientific
  • Sample Preparation
  • PCR Instrumentation
  • qRT-PCR reagents
  • Next Generation Sequencing
  • miRNA Mimics and Inhibitors
  • Toray Industries
  • WaferGen Bio-systems, Inc.
  • Wako Pure Chemical Ind. Ltd.

LIST OF EXHIBITS

ONE: EXECUTIVE SUMMARY

  • Figure 1-1: Historical and Projected Revenues in the Global Market for miRNA Tools and Services, 2013-2016 and 2020

TWO: INTRODUCTION AND APPLICATIONS OF miRNA

  • Table 2-1: Selected miRNAs Associated with Cancer (Non-small Cell Lung Cancer, Breast Cancer, Prostate Cancer, Colorectal Cancer, Gastric Cancer, Hepatocellular Carcinoma, Leukaemia, Lymphoma, Glioblastoma)
  • Table 2-2: Selected Extracellular miRNAs Potential Biomarkers in Cardiovascular Disorders (Coronary Arterial Disease, Acute myocardial infarction, Heart Failure)
  • Table 2-3: Selected miRNAs Associated with Neurological Disorders (Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, Epilepsy, Stroke)
  • Table 2-4: Selected miRNA-based Diagnostic Assays, 2016
  • Table 2-5: Selected miRNA-based Therapies in Clinical Development, 2016

THREE: miRNA PROFILING AND FUNCTIONAL ANALYSIS TECHNOLOGIES

  • Table 3-1: Advantages and Limitations of qRT-PCR in miRNA Expression Profiling, 2016
  • Table 3-2: Selected Challenges in the Profiling of miRNA Expression via qRT-PCR, 2016
  • Table 3-3: Selected Commercially Available miRNA qRT-PCR Reagents and Kits, 2016
  • Table 3-4: Advantages and Limitations of Microarrays in miRNA Expression Profiling, 2016
  • Table 3-5: Selected Commercial Hybridization-based Technologies for miRNA Expression Profiling, 2016
  • Figure 3-1: Typical Workflow of a miRNA Next-Generation Sequencing Experiment
  • Table 3-6: Current Advantages and Limitations of NGS in miRNA Profiling, 2016
  • Table 3-7: Selected Commercial NGS Library Preparation Kits for miRNA Profiling, 2016
  • Table 3-8: Selected Commercial miRNA Mimics, 2016
  • Table 3-9: Selected Commercial miRNA Inhibitors, 2016
  • Table 3-10: Selected Commercial miRNA Target Site Protectors/Blockers, 2016

FOUR: INDUSTRY STRUCTURE

  • Table 4-1: Industry Structure Summary, 2016
  • Table 4-2: Industry Structure - Selected Players in the Market for miRNA
  • Technologies, 2016
  • Table 4-3: Significant Trends in the Market for miRNA Analysis Tools and Services, 2016 (Near-term Impact [1 year to 2 years], Long-term Impact [3 years to 5 years])
  • Figure 4-1: Estimated Market Breakdown by Tools and Services, 2015
  • Figure 4-2: Estimated Market Breakdown by Geographic Region, 2015 (North America, Europe, ROW)
  • Table 4-4: Global Revenues and Forecast for the miRNA Tools and Services Market, 2013-2016 and 2020 (miRNA Analysis Tools, miRNA Services, Total market)
  • Figure 4-3: Global Revenues and Forecast for the miRNA Analysis Tools and Services Market, 2013-2016 and 2020
  • Table 4-5: Global Revenues and Forecast for the miRNA Analysis Tools and Services Market by Geographic Region, 2013-2016 and 2020 (North America, Europe, Rest of World, Total market)
  • Figure 4-4: Global Revenues and Forecast for the miRNA Analysis Tools and Services Market by Geographic Region, 2013-2016 and 2020 (Rest of World, Europe, North America, Total market)
  • Table 4-6: Global Revenues and Forecast for the miRNA Analysis Tools Market by Technology, 2013-2016 and 2020 (qRT-PCR, NGS, Hybridization-based, Functional Tools, Total Analysis Tools market)
  • Figure 4-5: Global Revenues and Forecast for the miRNA Analysis Tools Market by Technology, 2013-2016 and 2020 (Functional Tools, Hybridization-based, NGS,qRT-PCR, Total Market)
  • Table 4-7: Global Revenues and Forecast for the qRT-PCR Segment of the miRNA Analysis Tools Market, 2013-2016 and 2020
  • Table 4-8: Global Revenues and Forecast for the Hybridization-based Segment of the miRNA Analysis Tools Market, 2013-2016 and 2020
  • Table 4-9: Global Revenues and Forecast for the NGS segment of the miRNA Analysis Tools Market, 2013-2016 and 2020
  • Table 4-10: Global Revenues and Forecast for the Functional Tools Segment of the miRNA Analysis Tools Market, 2013-2016 and 2020
  • Table 4-11: Global Revenues and Forecast for the miRNA Services Market by Type of Service, 2013-2016 and 2020 (Expression profiling /analysis, Functional analysis, Total services market)
  • Figure 4-6: Global Revenues and Forecast for the miRNA Services Market, 2013-2016 and 2020 (Functional Analysis, Expression profiling / analysis, Total Market)

FIVE: COMPANY PROFILES

  • Table 5-1: Selected Companies Offering miRNA-specific Analysis Tools, 2016
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