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市場調查報告書

癌症治療的個體化遺傳基因療法市場

The Market for Personalized Gene Therapy Treatments for Cancer

出版商 Kalorama Information 商品編碼 323161
出版日期 內容資訊 英文 150 Pages
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癌症治療的個體化遺傳基因療法市場 The Market for Personalized Gene Therapy Treatments for Cancer
出版日期: 2014年12月23日 內容資訊: 英文 150 Pages
簡介

近年來,在癌症治療及個別化醫療化發展上一改外科手術及化學療法,而開始嚐試利用遺傳療法。在遺傳子療法的情況下,便是以正常遺傳子取代異常遺傳子,或是改變遺傳基因的反應(對何反應/不反應)。遺傳基因療法並非全是同一方法,而是配合各種癌症,各有不同的最佳治療法。

癌症治療用遺傳基因療法之潛在市場相關概括性分析,提供遺傳基因療法概要·種類,及各國·各企業的開發的配合措施,透過遺傳基因療法的癌症治療可能性及問題點,潛在的市場規模,彙整各種癌症市場詳細趨勢(治療藥市場整體規模及預測,遺傳基因療法的可能性,研究開發活動的進展,主要企業簡介等)等資訊,為您概述為以下內容。

摘要整理

遺傳基因療法概要

  • 遺傳學
  • 降低成本
  • 遺傳基因療法是什麼?
  • 遺傳基因療法的種類
    • 體細胞遺傳基因療法
    • 生殖系細胞的遺傳基因療法
  • 遺傳基因療法的應用領域
  • 法規概要
    • 孤兒藥指定的獎勵
  • 貿易快速審批·突破療法·迅速核准·優先核准概要
  • 美國各州的「Right to Try(新藥使用許可)」法案

癌症和遺傳基因療法

  • 癌症治療市場演進的過程
  • 藥理基因學
  • 癌症治療上遺傳基因療法的使用
  • 病毒載體和DNA療法
  • 癌症的治癒:最終目標
  • 全世界的癌症的影響度
  • 遺傳基因療法與癌症發生概要
  • 發生的風險
  • 針對新癌症治療藥「Allovectin-7」的開發上近來的問題
  • 開發計劃
  • 保險和醫療費給付的問題

針對膀胱癌之遺傳基因療法的市場預測

  • 膀胱癌概要
  • 發病率·死亡率的趨勢
  • 目前治療方法
  • 遺傳基因療法的研究活動
  • 市場機會
    • 膀胱癌治療市場現狀
    • 遺傳基因療法的潛在的市場規模:膀胱癌的情況

腦癌症的遺傳基因療法的市場預測

乳癌的遺傳基因療法的市場預測

大腸癌的遺傳基因療法的市場預測

頭部·頭部癌症的遺傳基因療法的市場預測

白血病的遺傳基因療法的市場預測

肝癌的遺傳基因療法的市場預測

肺癌的遺傳基因療法的市場預測

淋巴瘤的遺傳基因療法的市場預測

黑色素瘤的遺傳基因療法的市場預測

卵巢癌的遺傳基因療法的市場預測

胰臟癌的遺傳基因療法的市場預測

前列腺癌的遺傳基因療法的市場預測

遺傳基因療法與其他癌症

  • 其他癌症概要
    • 食道癌
    • 多發性骨髓瘤
    • 腎臟癌
    • 甲狀腺癌
  • 發病率·死亡率的趨勢
  • 遺傳基因療法的研究活動

癌症市場上遺傳基因療法:摘要與展望

  • 概要
  • 癌症治療的焦點:摘要
  • 癌症的遺傳基因療法:預測分析
  • 各癌症市場的遺傳基因療法的影響度

市場參與企業及資金提供企業的一覽

分析對象企業(研究活動,背景情況)

  • Adaptimmune Ltd.
  • Advantagene, Inc.
  • Amgen, Inc.
  • Bellicum Pharmaceuticals, Inc.
  • BioCancell Ltd.
  • Blubird Bio
  • Celgene
  • Celsion Corporation
  • Chengdu Shi Endor Biological Engineering Technology Co., Ltd.
  • Cold Genesys, Inc.
  • Genprex, Inc.
  • MaxiVax SA
  • 桃太郎起源
  • MultiVir, Inc.
  • OncoSec Medical, Inc.
  • Sevion Therapeutics, Inc.
  • SynerGene Therapeutics, Inc.
  • TaKaRa BIO
  • Tocagen, Inc.
  • VBL Therapeutics Ltd.
  • Ziopharm Oncology, Inc.
目錄
Product Code: KLI5421818

This report, The Market for Personalized Gene Therapy Treatments For Cancer provides an exhaustive review of the market potential for relatively new approach in cancer research. It involves modification of genes instead of using a surgical method or chemical drug product. Essentially, gene therapies replace an abnormal gene with a normal gene, or changes the response of a gene (turn on or off). Not all of the approaches to gene therapy are the same, and different cancers appear to respond better to different therapies.

Several gene therapy technologies have the ability to work in combination with other treatment options to enhance the effectiveness of a therapeutic regimen. Gene therapy is also designed to target specific cells making treatment much less damaging to healthy cells.

This report discusses those treatments and estimates market size and market potential for personalized medicine using gene therapy. As part of its data offering, the report provides disease incidence, gene therapy product developments and market forecasts for the following types of cancer:

  • Bladder Cancer
  • Brain Cancer
  • Breast Cancer
  • Head & Neck
  • Colorectal Cancer
  • Leukemia Cancer
  • Liver Cancer
  • Lung Cancer
  • Lymphoma
  • Melanoma
  • Leukemia
  • Pancreatic Cancer
  • Prostate Cancer
  • Ovarian Cancer
  • Other Cancer

In addition the report provides:

  • Overview of Gene Therapy
  • Overall Market Size and Forecast
  • Cancer Therapeutic Market Totals
  • Discussion of Somati vs. Germ Line Gene Therapy
  • R&D Activities
  • Company Profiles

Historically, cancer treatments have been very invasive and detrimental process to the body. However, there are numerous new techniques available for those with cancer that are not as invasive and detrimental to the body as a whole. These treatments range from the severely alternative to the more traditional. Newer alternative treatments are more precise and much less invasive as some of the traditional methods. Gene therapy is the most prominent new form of these alternative treatments. It is being studied as a way to change how a cell functions, for example, by stimulating the cells of the immune system to attack cancer cells.

Companies discussed in this report include those which have registered trials in Phase I through Phase III development and have promising development activities. These include:

  • Adaptimmune Ltd.
  • Advantagene, Inc.
  • Amgen, Inc.
  • Bellicum Pharmaceuticals, Inc.
  • BioCancell Ltd.
  • Blubird Bio
  • Celgene
  • Celsion Corporation
  • Chengdu Shi Endor Biological Engineering Technology Co., Ltd.
  • Cold Genesys, Inc.
  • Genprex, Inc.
  • MaxiVax SA
  • Momotaro-Gene, Inc.
  • MultiVir, Inc.
  • OncoSec Medical, Inc.
  • Sevion Therapeutics, Inc.
  • SynerGene Therapeutics, Inc.
  • Takara Bio, Inc.
  • Tocagen, Inc.
  • VBL Therapeutics Ltd.
  • Ziopharm Oncology, Inc.

Table of Contents

EXECUTIVE SUMMARY

  • Overview and Scope of Study
  • Methodology
  • How Personalized Medicine is Changing the Cancer Market
  • Market Potential for Gene Therapy in Cancer

GENE THERAPY OVERVIEW

  • Genetics
  • Reducing Costs
  • What is Gene Therapy?
  • Types of Gene Therapy
  • Somatic Gene Therapy
  • Germ Line Gene Therapy
  • Gene Therapy Applications
  • Regulation Overview
  • Orphan Drug Designation Incentives
  • Fast Track, Breakthrough Therapy, Accelerated Approval and Priority Review
  • Fast Track
  • Breakthrough Therapy
  • Accelerated Approval
  • Priority Review
  • State ‘Right to Try' Laws

CANCER AND GENE THERAPY

  • How has the Cancer Treatment Market Evolved?
  • Pharmacogenomics
  • Using Gene Therapy to Treat Cancer
  • Viral Vectors and DNA Therapies
  • Curing Cancer - The Ultimate Goal
  • Global Cancer Impact
  • Gene Therapy and Cancer Development Overview
  • Development Risk
  • A Recent Disappointment in Novel Cancer Therapy Development - Allovectin-7
  • Development Programs
  • Insurance and Reimbursement Issues

GENE THERAPY OUTLOOK IN BLADDER CANCER

  • Bladder Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • BioCancell Ltd.
  • Research Activities
  • Company Background
  • Cold Genesys, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Bladder Cancer
  • Potential Market for Gene Therapy in Bladder Cancer

GENE THERAPY OUTLOOK IN BRAIN CANCER

  • Brain Cancer Overview
  • Glioblastoma
  • Neuroblastoma
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Advantagene, Inc.
  • Research Activities
  • Company Background
  • BioCancell Ltd.
  • Research Activities
  • Company Background
  • Celsion Corporation
  • Research Activities
  • Company Background
  • Tocagen, Inc.
  • Research Activities
  • Company Background
  • VBL Therapeutics Ltd.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Brain Cancer
  • Potential Market for Gene Therapy in Brain Cancer

GENE THERAPY OUTLOOK IN BREAST CANCER

  • Breast Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • ZIOPHARM Oncology, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Breast Cancer
  • Potential Market for Gene Therapy in Breast Cancer

GENE THERAPY OUTLOOK IN COLORECTAL CANCER

  • Colorectal Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • MultiVir, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Colorectal Cancer
  • Potential Market for Gene Therapy in Colorectal Cancer

GENE THERAPY OUTLOOK IN HEAD & NECK CANCER

  • Head and Neck Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Chengdu Shi Endor Biological Engineering Technology Co., Ltd
  • Research Activities
  • Market Opportunity
  • Current Market for Treating Head and Neck Cancer
  • Potential Market for Gene Therapy in Head and Neck Cancer

GENE THERAPY OUTLOOK IN LEUKEMIA

  • Leukemia Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Bellicum Pharmaceuticals, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Leukemia
  • Potential Market for Gene Therapy in Leukemia

GENE THERAPY OUTLOOK IN LIVER CANCER

  • Liver Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • MultiVir, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Liver Cancer
  • Potential Market for Gene Therapy in Liver Cancer

GENE THERAPY OUTLOOK IN LUNG CANCER

  • Lung Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Genprex, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Lung Cancer
  • Potential Market for Gene Therapy in Lung Cancer

GENE THERAPY OUTLOOK IN LYMPHOMA

  • Lymphoma Overview
  • Non-Hodgkin's Lymphoma
  • Hodgkin's Lymphoma
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Bellicum Pharmaceuticals, Inc.
  • Research Activities
  • Company Background
  • Sevion Therapeutics, Inc.
  • Research Activities
  • Company Background
  • OncoSec Medical, Inc.
  • Research Activities
  • Company Background
  • Takara Bio, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Lymphoma
  • Potential Market for Gene Therapy in Lymphoma

GENE THERAPY OUTLOOK IN MELANOMA

  • Melanoma Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Adaptimmune Limited
  • Research Activities
  • Company Background
  • Amgen, Inc.
  • Research Activities
  • Company Background
  • OncoSec Medical, Inc.
  • Research Activities
  • Company Background
  • ZIOPHARM Oncology, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Melanoma
  • Potential Market for Gene Therapy in Melanoma

GENE THERAPY OUTLOOK IN OVARIAN CANCER

  • Ovarian Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Adaptimmune Limited
  • Research Activities
  • Company Background
  • BioCancell Ltd.
  • Research Activities
  • Company Background
  • Celsion Corporation
  • Research Activities
  • Company Background
  • VBL Therapeutics Ltd.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Ovarian Cancer
  • Potential Market for Gene Therapy in Ovarian Cancer

GENE THERAPY OUTLOOK IN PANCREATIC CANCER

  • Pancreatic Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Advantagene, Inc.
  • Research Activities
  • Company Background
  • BioCancell Ltd.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Pancreatic Cancer
  • Potential Market for Gene Therapy in Pancreatic Cancer

GENE THERAPY OUTLOOK IN PROSTATE CANCER

  • Prostate Cancer Overview
  • Trends in Incidence and Mortality
  • Current Approaches to Treatment
  • Gene Therapy Research Activities
  • Advantagene, Inc.
  • Research Activities
  • Company Background
  • Momotaro-Gene, Inc.
  • Research Activities
  • Company Background
  • Market Opportunity
  • Current Market for Treating Prostate Cancer
  • Potential Market for Gene Therapy in Prostate Cancer

GENE THERAPY AND OTHER CANCERS

  • Other Cancer Overview
  • Esophagus Cancer
  • Multiple Myeloma
  • Renal Cancer
  • Thyroid Cancer
  • Trends in Incidence and Mortality
  • Esophageal Cancer
  • Multiple Myeloma
  • Renal Cancer
  • Thyroid Cancer
  • Gene Therapy Research Activities for Other or Unspecific Cancer
  • Advantagene, Inc.
  • Research Activities
  • Company Background
  • Bluebird Bio
  • Research Activities
  • Company Background
  • MaxiVAX
  • Research Activities
  • Company Background
  • OncoSec Medical, Inc.
  • Research Activities
  • Company Background
  • Sevion Therapeutics, Inc.
  • Research Activities
  • Company Background
  • Takara Bio, Inc.
  • Research Activities
  • Company Background
  • VBL Therapeutics Ltd.
  • Research Activities
  • Company Background
  • Other Companies

GENE THERAPY IN CANCER MARKET SUMMARY AND OUTLOOK

  • Overview
  • Cancer Focus Summary
  • Cancer Gene Therapy Forecast Analysis
  • Impact of Gene Therapy on Specific Cancer Markets

INDUSTRY PARTICIPANTS AND CONTRIBUTORS

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