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市場調查報告書

生物標記的全球市場 (癌症標記、心臟標記、免疫疾病標記、感染疾病標記、其他)

The Global Market for Biomarkers (Cancer Markers, Cardiac Markers, Immunological Disease Markers, Infectious Disease Markers, Others)

出版商 Kalorama Information 商品編碼 288790
出版日期 內容資訊 英文 683 Pages
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生物標記的全球市場 (癌症標記、心臟標記、免疫疾病標記、感染疾病標記、其他) The Global Market for Biomarkers (Cancer Markers, Cardiac Markers, Immunological Disease Markers, Infectious Disease Markers, Others)
出版日期: 2015年12月10日 內容資訊: 英文 683 Pages
簡介

生物標記,是生物學、生物化學性的分子,可測量遺傳基因變化或及其他特徵,以及表示或預測疾病、風險、可預計的反應。生物標記用於包含疾病風險的預測、診斷、預後預測,及尋找對個人的適當治療方法等,廣泛的診斷用途。

本報告提供全球生物標記市場相關調查、市場發展預測和成長率、各市場區隔趨勢,及加入此市場的企業簡介,為您概述為以下內容彙整。

第1章 摘要整理

第2章 簡介

第3章 生物標記的識別、分析所使用的主要技術

  • 免疫檢測法
  • 免疫檢測設備的平台
  • 蛋白質微陣列
  • 合成時的譯解法 (SBS法:Sequence-by-Synthesis 法)
  • SOLiD
  • 質譜分析法
  • 非侵襲產前檢查

第4章 癌症的生物標記

  • 概要
  • 癌症生物標記
  • 癌症的風險評估
  • 癌症篩檢
  • 癌症的診斷、監測
  • 預後預測
  • 個體化醫療/精密檢驗

第5章 心血管疾病的生物標記

  • 概要
  • 急性心肌梗塞、急性冠狀動脈症候群
  • 心臟衰竭
  • 脂質疾病

第6章 免疫疾病的生物標記

  • 自體免疫疾病生物標記
  • 發炎/發炎性疾病生物標記
  • 其他主要免疫相關疾病

第7章 感染疾病的生物標記

  • 概要
  • 目前感染疾病診斷及新威脅
  • 抗生素抗性
  • 肺血症

第8章 神經系統疾病的生物標記

  • 概要
  • 老年癡呆症
  • 適合神經系統疾病的新生物標記

第9章 其他的疾病用生物標記

  • 概要
  • 新生物標記開發企業

第10章 契約

第11章 生物標記:市場成長的促進要素、課題

第12章 生物標記市場分析

第13章 企業簡介:生物標記企業

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目錄
Product Code: KLI5789361

Biomarkers are biological or biochemical molecules, genetic changes, or other characteristics that can be measured, and that indicate or predict a condition, risk, or likely response. Biomarkers can be used for a range of diagnostic applications including predicting disease risk, diagnosis, predicting prognosis, identifying appropriate therapy for an individual, monitoring disease or for return of a disease, and other applications. Biomarkers also have important roles in drug discovery and development. The Global Market for Biomarkers analyzes the current and future markets for biomarkers.

Segmentation of Individual Biomarker and Relevant Category Markets

Market analyses in this report cover world markets for biomarker diagnostic markets. Biomarker markets are broken out to individual markers where possible, and in category market segments where tests are bundled. The report includes the following segmentation:

  • Worldwide Diagnostic Biomarker Market by Disease Indication - 2015 and 2020 (Cancer, Cardiovascular disease, Autoimmune disease and allergy, Infectious disease, Other disease applications, Total)
  • Worldwide Cancer Biomarkers Diagnostic Market - 2015 and 2020 (IHC, ISH, PSA, CEA, CA 125, AFP, Other Immunoassays - Tumor Markers, Flow Cytometry, Fecal occult blood, Rapid Tests - PSA, NMP22, EGFR/HER2 Segment, Total)
  • Worldwide Cardiac Marker Diagnostic Market - 2015 and 2020 (Acute Condition Cardiac Marker Segment: CK-MB, troponin I, troponin T, myoglobin, brain natriuretic peptide [BNP]; Other Cardiac Marker Segment: proBNP, hsCRP, homocysteine, others; Cholesterol/Lipids; Coagulation: PT/INR - lab, D-dimer, Molecular [Thrombophilia SNPs], POC Cardiac Marker Segment; Total)
  • Worldwide Autoimmune Disease and Allergy Biomarkers Diagnostic Market - 2015 and 2020
  • Worldwide Infectious Disease Biomarkers Diagnostic Market - 2015 and 2020 (Laboratory immunoassays: Hepatitis, HIV, STDs, TORCH, Respiratory, Sepsis, Parasitology, Mycology, Others; Rapid immunoassays: Influenza, HIV, Malaria, Hepatitis, STDs, C. difficile, E. coli, Strep A, H. pylori, Others; Molecular assays: Healthcare-Acquired Infections [HAIs], HIV, Hepatitis, Chlamydia/Gonorrhea [CT/NG], HPV, Respiratory, Mycobacteria/TB, Other; Total)
  • Worldwide Diagnostic Market for Selected Other Biomarkers - 2015 and 2020 (General Clinical Chemistry, Fertility/Pregnancy, Thyroid, Diabetes/HbA1c, Chromosome Analysis and Inherited Disease, Cystic Fibrosis, Other, Total)
  • Worldwide Biomarker Market - Diagnostic versus Research Applications - 2015 and 2020
  • Worldwide Biomarker Market by Geography - 2015 and 2020 (North America, European Union, Japan, ROW, Total)

The world markets for biomarkers and biomarker tests are provided in U.S. dollars for 2015 and 2020. The worldwide market for biomarkers by disease indication is provided, including the market for tests for biomarkers (diagnostics products) sold to clinical laboratories, and also products sold to researchers.

In addition, The Global Market for Biomarkers includes financial information on deals involving biomarker companies. In the table summarizing these deals, for companies that reported this information in currencies other than U.S. dollars, both the actual reported financial information and an estimated value in U.S. dollars at the time of the agreement are provided.

The biomarker market is large, reflecting the large market for diagnostic tests based on these biomarkers, and also the ongoing efforts to discovery, validate, and commercialize new biomarkers. Growth in this market is fueled by factors that are fostering the growth of both the research and the diagnostics market. Market drivers and challenges are discussed in the report.

Over 100 Companies Profiled

The large and growing biomarker market has attracted a lot of attention, and companies entering the market. Thus this has become a highly competitive market. The report profiles companies involved in the biomarkers market, including:

  • 14M Genomics Ltd.
  • 20/20 GeneSystems, Inc.
  • 23andMe, Inc.
  • A&G Pharmaceutical, Inc.
  • Abacus Diagnostica Oy
  • Abbott Laboratories
  • Abcodia Ltd.
  • Accelerate Diagnostics, Inc.
  • Acobiom
  • ACT Genomics Co., Ltd.
  • Acumen Pharmaceuticals, Inc.
  • Adaptive Biotechnologies Corporation
  • Adlyfe Inc.
  • Admera Health (A GENEWIZ Company)
  • AESKU.DIAGNOSTICS
  • Affymetrix, Inc.
  • Agena Bioscience Inc.
  • Agendia NV
  • Agilent Technologies Inc.
  • Alere Inc.
  • Almac Group Limited
  • ALPCO
  • Amarantus BioScience Holdings, Inc.
  • Ambry Genetics Corp.
  • Aperiomics, Inc.
  • ApoCell, Inc.
  • Applied Proteomics, Inc.
  • Associates of Cape Cod, Inc. (ACC)
  • Asuragen, Inc.
  • AsymmetRx Medical, Inc.
  • Athena Diagnostics, Inc. (A Quest Diagnostics Business)
  • Atlas Genetics Ltd.
  • Atossa Genetics Inc.
  • Augurex Life Sciences Corp.
  • Augurix SA/Augurix Diagnostics
  • Avant Diagnostics, Inc. (Formerly Arrayit Diagnostics Inc.)
  • Axela, Inc.
  • Axis-Shield Diagnostics, Ltd. (An Alere Company)
  • AXO Science
  • Banyan Biomarkers, Inc.
  • Beckman Coulter, Inc.
  • Becton, Dickinson and Company (BD)
  • BG Medicine, Inc.
  • The Binding Site Group Ltd.
  • Biocartis SA
  • Biocrates Life Sciences AG
  • Biodesix, Inc.
  • BioFire Diagnostics, LLC (Acquired by bioMérieux)
  • Biohit Oyj
  • Bioinnovation Solutions SA
  • BioMarker Strategies
  • BioMedomics, Inc.
  • bioMérieux SA
  • BioMosaics Inc.
  • BioPorto Diagnostics A/S
  • Bio-Rad Laboratories, Inc.
  • BioSystems International
  • bioTheranostics, Inc. (A bioMérieux Company)
  • Biotype Diagnostic GmbH
  • BIOUNIVERSA s.r.l.
  • Cancer Genetics, Inc.
  • Caprion, Inc.
  • CardioDx, Inc.
  • CardioGenics Holdings Inc.
  • CareDx, Inc.
  • Caris Life Sciences
  • Castle Biosciences, Inc.
  • CD Diagnostics, Inc.
  • Cellmid Ltd.
  • Centogene AG
  • Cepheid
  • Chronix Biomedical, Inc.
  • Clarient Diagnostic Services, Inc.
  • Courtagen Life Sciences, Inc.
  • Crescendo Bioscience (Subsidiary of Myriad Genetics)
  • Critical Diagnostics
  • Curetis AG
  • Cynvenio Biosystems, Inc.
  • Dako A/S (An Agilent Company)
  • Danaher Corporation
  • deCODE genetics
  • Diadexus, Inc.
  • DiaGenic ASA
  • Diagenics SE
  • Diaxonhit
  • DNA Electronics Ltd. (DNAe)
  • EntroGen, Inc.
  • Epic Sciences, Inc.
  • Epigenomics AG
  • Epinex Diagnostics, Inc.
  • Eutropics Pharmaceuticals
  • Exact Sciences Corporation
  • Exiqon A/S
  • Foundation Medicine, Inc.
  • Fujirebio Inc.
  • Fujirebio Diagnositics, Inc.
  • Gamma Therapeutics, Inc.
  • Genalyte, Inc.
  • GeneCentric Diagnostics, Inc.
  • Genection, Inc. (An Invivoscribe Company)
  • GeneNews Limited and Innovative Diagnostic Laboratory
  • GenomeDx Biosciences
  • Genomeon LLC
  • Genomic Health, Inc.
  • Genomic Vision
  • Genoptix (A Novartis Company)
  • Guardant Health, Inc.
  • HalioDx
  • Helomics Corporation
  • Hologic, Inc.
  • Illumina, Inc.
  • Immunexpress
  • Integrated Diagnostics, Inc.
  • Intrinsic LifeSciences
  • Myriad Genetics, Inc.
  • NanoString Technologies, Inc.
  • NeoGenomics, Inc./NeoGenomics Laboratories
  • Oncolab, Inc.
  • Oncospire Genomics
  • OPKO Health, Inc./OPKO Diagnostics
  • ORGENTEC Diagnostika GmbH
  • Orion Genomics
  • Ortho-Clinical Diagnostics
  • Oxford Gene Technology
  • Proteome Sciences plc
  • Psynova Neurotech Ltd.
  • QIAGEN N.V.
  • Quanterix Corporation
  • Randox Laboratories Ltd.
  • Rapid Pathogen Screening, Inc.
  • ReLIA Diagnostics, Inc.
  • RENESE UG
  • Roche
  • Siemens Healthcare Diagnostics
  • Sysmex Corporation
  • Thermo Fisher Scientific, Inc.
  • Tosoh Corporation
  • Ventana Medical Systems, Inc. (Member of the Roche Group)
  • Wako Pure Chemical Industries, Ltd.
  • XRGenomics LTD
  • ZEUS Scientific, Inc.

A broad definition of biomarkers is being used in this report. Biomarkers in this report include molecules or other characteristics that can be measured, and are indicators of a health, risk of disease, disease or other condition, prognosis, response to therapy, or other biological effect. This definition includes biomarkers that are used in drug development as surrogates, markers of drug safety, or other applications. Panels of multiple markers or analytes, which combined provide the result of one “biomarker” are also included as biomarkers in this report as analytes.

The information presented in this report is derived from publicly available information sources such as company reports and announcements, government reports and databases, medical organization reports, medical associations, and other publications. The analysis is based on the author's industry knowledge combined with literature searches and discussions with industry professionals and experts in the areas of point-of-care tests, decentralized healthcare and healthcare economics.

Table of Contents

ONE: EXECUTIVE SUMMARY

  • Overview
  • Scope and Methodology
  • Market Overview
  • Prognosis for Growth

TWO: INTRODUCTION

  • What Are Biomarkers?
  • Point-of-View

THREE: SELECTED TECHNOLOGIES USED TO IDENTIFY AND ANALYZE BIOMARKERS

  • Immunoassays
  • Overview - Immunoassays
  • Immunoassay Instrument Platforms
  • Immunohistochemistry (IHC)
  • Flow Cytometry
  • In Situ Hybridization
  • Nucleic Acid Amplification Technologies
  • Analysis of Gene Expression Patterns (Gene Signatures)
  • Microarrays
  • Protein Microarrays
  • DNA Microarrays
  • Chromosomal Microarrays
  • Tissue Microarrays
  • Sequencing Technologies
  • Sanger Sequencing
  • Early Next Generation Sequencing Technologies
  • Sequencing by Synthesis (SBS)
  • Supported Oligonucleotide Ligation and Detection (SOLiD)
  • Ion Torrent Sequencing
  • Newer Next Generation Sequencing Technologies
  • Sequencing Technologies Summary - Impact on Biomarkers
  • Mass Spectrometry
  • Mass Spectrometry Technology
  • Research and Clinical Applications of Mass Spectrometry
  • Non-Invasive Prenatal Testing
  • Liquid Biopsies - Circulating Tumor Cells and Circulating Tumor DNA(Cell Free DNA)
  • Digital Pathology and Image Cytometry
  • Information Technology

FOUR: CANCER BIOMARKERS

  • Overview
  • Cancer Biomarkers
  • Assessing Risk of Cancer
  • Cancer Screening
  • Diagnosis and Monitoring of Cancer
  • Predicting Prognosis
  • Personalized Medicine/Precision Testing
  • Competition in Cancer Biomarkers

FIVE: CARDIOVASCULAR DISEASE BIOMARKERS

  • Overview
  • Acute Myocardial Infarction and Acute Coronary Syndrome
  • Heart Failure
  • Lipid Disorders

SIX: IMMUNOLOGICAL DISEASE BIOMARKERS

  • Autoimmune Disease Biomarkers
  • Inflammation/Inflammatory Disease Biomarkers
  • Selected Other Immune-Related Disorders

SEVEN: INFECTIOUS DISEASE BIOMARKERS

  • Overview
  • Current Infectious Disease Diagnostics and Emerging Threats
  • Antibiotic Resistance
  • Sepsis

EIGHT: NEUROLOGICAL DISEASE BIOMARKERS

  • Overview
  • Alzheimer's Disease
  • Emerging Biomarkers for Neurological Disorders

NINE: NOVEL BIOMARKERS FOR OTHER DISEASES

  • Overview
  • Companies Developing Novel Biomarkers

TEN: DEALS

ELEVEN: BIOMARKERS - MARKET DRIVERS AND CHALLENGE

  • Biomarker Markets
  • Market Drivers for Diagnostic Applications of Biomarkers
  • Issues and Hurdles Faced by In Vitro Diagnostic Companies
  • Market Drivers for Research Applications of Biomarkers
  • Biomarkers in Drug Development
  • Pharmacogenomic Biomarkers
  • Advances in Technology Changing the Future of Biomarkers
  • Biomarker Panels
  • Working Together to Discover and Validate New Biomarkers - Alliances,
  • Consortiums, and Other Groups
  • Validation of Biomarkers
  • Future Prospects

TWELVE: BIOMARKER MARKET ANALYSIS

  • Diagnostic Biomarker Market by Disease Indication
  • Cancer Biomarkers
  • Cardiovascular Disease Biomarkers
  • Autoimmune Disease and Allergy Biomarkers
  • Infectious Disease Biomarkers
  • Biomarkers for Other Diseases
  • Biomarker Market - Research versus Diagnostic Applications
  • Biomarker Market - Geographical Distribution

THIRTEEN: COMPANY PROFILES: BIOMARKER COMPANIES

  • 14M Genomics Ltd.
  • 20/20 GeneSystems, Inc
  • 23andMe, Inc.
  • A&G Pharmaceutical, Inc.
  • Abacus Diagnostica Oy
  • Abbott Laboratories
  • Recent Revenue History
  • Company Overview - Focusing on Biomarkers
  • Abcodia Ltd.
  • Accelerate Diagnostics, Inc.
  • Recent Revenue History
  • Company Overview
  • Acobiom
  • ACT Genomics Co., Ltd.
  • Acumen Pharmaceuticals, Inc.
  • Adaptive Biotechnologies Corporation
  • Adlyfe Inc.
  • Admera Health (A GENEWIZ Company)
  • AESKU.DIAGNOSTICS
  • Affymetrix, Inc.
  • Recent Revenue History
  • Company Overview
  • Agena Bioscience Inc.
  • Agendia NV
  • Agilent Technologies Inc.
  • Recent Revenue History
  • Company Overview
  • Alere Inc.
  • Recent Revenue History
  • Company Overview
  • Almac Group Limited
  • ALPCO
  • Amarantus BioScience Holdings, Inc.
  • Ambry Genetics Corp.
  • Aperiomics, Inc.
  • ApoCell, Inc.
  • Applied Proteomics, Inc.
  • Associates of Cape Cod, Inc. (ACC)
  • Asuragen, Inc.
  • AsymmetRx Medical, Inc.
  • Athena Diagnostics, Inc. (A Quest Diagnostics Business)
  • Atlas Genetics Ltd
  • Atossa Genetics Inc.
  • Recent Revenue History
  • Company Overview
  • Augurex Life Sciences Corp.
  • Augurix SA/Augurix Diagnostics
  • Avant Diagnostics, Inc. (Formerly Arrayit Diagnostics Inc.)
  • Axela, Inc
  • Axis-Shield Diagnostics, Ltd. (An Alere Company)
  • Recent Revenue History
  • Company Overview
  • AXO Science
  • Banyan Biomarkers, Inc.
  • Beckman Coulter, Inc.
  • Recent Revenue History
  • Company Overview
  • Becton, Dickinson and Company (BD)
  • Recent Revenue History
  • Company Overview
  • BG Medicine, Inc.
  • Recent Revenue History
  • Company Overview
  • The Binding Site Group Ltd.
  • Recent Revenue History
  • Company Overview
  • Biocartis SA
  • Recent Revenue History
  • Company Overview
  • Biocrates Life Sciences AG
  • Biodesix, Inc.
  • BioFire Diagnostics, LLC (Acquired by bioMérieux)
  • Recent Revenue History and Other Financial Information
  • Company Overview
  • Biohit Oyj
  • Recent Revenue History
  • Company Overview
  • Bioinnovation Solutions SA
  • BioMarker Strategies
  • BioMedomics, Inc.
  • bioMérieux SA
  • Recent Revenue History
  • Company Overview
  • BioMosaics Inc.
  • BioPorto Diagnostics A/S
  • Recent Revenue History
  • Company Overview
  • Bio-Rad Laboratories, Inc.
  • Recent Revenue History
  • Company Overview
  • BioSystems International
  • bioTheranostics, Inc. (A bioMérieux Company)
  • Biotype Diagnostic GmbH
  • BIOUNIVERSA s.r.l.
  • Cancer Genetics, Inc.
  • Recent Revenue History
  • Company Overview
  • Caprion, Inc.
  • CardioDx, Inc.
  • CardioGenics Holdings Inc.
  • CareDx, Inc.
  • Recent Revenue History
  • Company Overview
  • Caris Life Sciences
  • Castle Biosciences, Inc.
  • CD Diagnostics, Inc.
  • Cellmid Ltd.
  • Centogene AG
  • Cepheid
  • Recent Revenue History
  • Company Overview
  • Chronix Biomedical, Inc.
  • Clarient Diagnostic Services, Inc. (A GE Healthcare Company; Being Acquired by NeoGenomics, Inc.)
  • Recent Revenue History
  • Company Overview
  • Courtagen Life Sciences, Inc.
  • Crescendo Bioscience (Subsidiary of Myriad Genetics)
  • Critical Diagnostics
  • Curetis AG
  • Cynvenio Biosystems, Inc.
  • Dako A/S (An Agilent Company)
  • Recent Revenue History
  • Company Overview
  • Danaher Corporation
  • Recent Revenue History
  • Company Overview
  • deCODE genetics
  • Diadexus, Inc.
  • Recent Revenue History
  • Company Overview
  • DiaGenic ASA
  • Diagenics SE
  • Diagenics International Corporation
  • Diaxonhit
  • Recent Revenue History
  • Company Overview
  • DNA Electronics Ltd. (DNAe)
  • EntroGen, Inc.
  • Epic Sciences, Inc.
  • Epigenomics AG
  • Recent Revenue History
  • Company Overview
  • Epinex Diagnostics, Inc.
  • Eutropics Pharmaceuticals
  • Exact Sciences Corporation
  • Recent Revenue History
  • Company Overview
  • Exiqon A/S
  • Recent Revenue History
  • Company Overview
  • Foundation Medicine, Inc.
  • Recent Revenue History
  • Company Overview
  • Fujirebio Inc.
  • Fujirebio Diagnositics, Inc.
  • Recent Revenue History
  • Company Overview
  • Gamma Therapeutics, Inc.
  • Genalyte, Inc.
  • GeneCentric Diagnostics, Inc.
  • Genection, Inc. (An Invivoscribe Company)
  • GeneNews Limited and Innovative Diagnostic Laboratory
  • GenomeDx Biosciences
  • Genomeon LLC
  • Genomic Health, Inc.
  • Recent Revenue History
  • Company Overview
  • Genomic Vision
  • Recent Revenue History
  • Company Overview
  • Genoptix (A Novartis Company)
  • Guardant Health, Inc.
  • HalioDx
  • Helomics Corporation
  • Hologic, Inc.
  • Recent Revenue History
  • Company Overview
  • Illumina, Inc.
  • Recent Revenue History
  • Company Overview
  • Immunexpress
  • Integrated Diagnostics, Inc.
  • Intrinsic LifeSciences
  • Myriad Genetics, Inc.
  • Recent Revenue History
  • Company Overview
  • NanoString Technologies, Inc.
  • Recent Revenue History
  • Company Overview
  • NeoGenomics, Inc./NeoGenomics Laboratories
  • Recent Revenue History
  • Company Overview
  • Oncolab, Inc.
  • Oncospire Genomics
  • OPKO Health, Inc./OPKO Diagnostics
  • Recent Revenue History
  • Company Overview
  • ORGENTEC Diagnostika GmbH
  • Orion Genomics
  • Ortho-Clinical Diagnostics
  • Recent Revenue History
  • Company Overview
  • Oxford Gene Technology
  • Proteome Sciences plc
  • Recent Revenue History
  • Company Overview
  • Psynova Neurotech Ltd.
  • QIAGEN N.V.
  • Recent Revenue History
  • Company Overview
  • Quanterix Corporation
  • Randox Laboratories Ltd
  • Rapid Pathogen Screening, Inc.
  • ReLIA Diagnostics, Inc.
  • RENESE UG
  • Roche
  • Recent Revenue History
  • Company Overview
  • Siemens Healthcare Diagnostics
  • Recent Revenue History
  • Company Overview
  • Sysmex Corporation
  • Recent Revenue History
  • Company Overview
  • Thermo Fisher Scientific, Inc.
  • Recent Revenue History
  • Company Overview
  • Tosoh Corporation
  • Recent Revenue History
  • Company Overview
  • Ventana Medical Systems, Inc. (Member of the Roche Group)
  • Wako Pure Chemical Industries, Ltd.,
  • XRGenomics LTD
  • ZEUS Scientific, Inc.
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