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市場調查報告書

自動少量調劑趨勢 2016年

Automated Low Volume Dispensing Trends 2016

出版商 HTStec Ltd 商品編碼 355556
出版日期 內容資訊 英文 52 Pages
商品交期: 最快1-2個工作天內
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自動少量調劑趨勢 2016年 Automated Low Volume Dispensing Trends 2016
出版日期: 2016年03月31日 內容資訊: 英文 52 Pages
簡介

本報告提供自動少量調劑 (LVD) 設備、系統相關全球性線上的基準調查結果相關分析。

目錄

  • 摘要整理
  • 目錄
  • 調查方法
  • 受訪者的組織與回答
  • 受訪者所屬企業及組織
  • 受訪者的地區
  • 受訪者的工作職位
  • 受訪者的主要群組活動
  • 液體處理的專門技術及調劑設備的取用
  • 現在使用LVD的受訪者
  • 現在受訪者取用、利用的LVD系統/設備 (1)
  • 現在受訪者取用、利用的LVD系統/設備 (2)
  • LVD的方法偏好的技術
  • 使用的LVD範圍
  • 調查結果的摘要 (1)
  • LVD應用所需的最小的液滴尺寸
  • 同樣的自動LVD系統所必要的動態調劑範圍
  • LVD系統的極為廣泛的動態調劑範圍的重要性
  • LVD的調劑流通管道的偏好的數、其他
  • 調查結果的摘要 (2)
  • 受訪者的應用中最必要的LVD技術
  • 受訪者關心的廣泛應用領域
  • 受訪者最關心的特定應用領域
  • 引進聲波式液滴噴射技術的主要阻礙因素
  • 不久的將來,購買新的LVD系統的可能性
  • 研究LVD系統的購買的時候最重要的功能
  • LVD計量儀器購買的年度預算
  • 自動LVD計量儀器市場預測
  • 目前LVD的主要阻礙因素、其他
  • 調查結果的摘要 (3)
目錄

Executive Summary

This market report summarizes the results of HTStec's industry-wide global web-based benchmarking survey on automated low volume dispensing carried out in March 2016.

The survey was initiated by HTStec as part of its tracking of emerging life science marketplaces and in some aspects updates HTStec's earlier report on the subject published 10 years ago.

The questionnaire was compiled to meet the needs, requirements and interests of the automated liquid handling vendor community and of manufacturers/developers of new low volume (nanoliter to picoliter) dispensing technology who wish to gain a better understanding of the current and future market requirements for fully automated low volume dispensing (LVD) systems.

Equal emphasis was given to soliciting opinion from all areas and organisations were automated LVD is being investigated irrespective of application.

The survey looked at the following aspects of automated LVD as practiced today (2016) and in some cases as predicted/wanted for the future (2018): current use of LVD; LVD systems/devices respondents have access to and use today; preferred technology approach to LVD; LV dispense ranges used; minimum droplet size required; ideal dynamic dispensing range; importance of a very wide dynamic dispensing range; preferred number of dispensing channels and system flexibility; receptacles, surface materials and fluid types to be dispensed in low volumes; importance of an aspirate function in a LVD system; importance of dispensing/ejecting samples without the involvement of disposable tips or tip washing; acceptable dead volume for an automated LVD system; acceptable dead volume for a source microplate well, tube or container; need for automated feed of source and destination substrates; preferred method for the integration of an automated LVD system; additional functionality that needs to be integrated with a LVD to create a useful automated system; total walk-away plate stacker/hotel capacity required on an automated system; LVD technology most needed for respondent's application(s); broad application areas of LVD; most wanted specific application areas of LVD; main limitations to adopting acoustic droplet ejection; probability of purchasing a new LVD system in the near future; most important features of an automated LVD system; type of automated LVD respondents are most interested in purchasing; existing LVD systems respondents currently find most appealing from a purchasing perspective; budgets for purchasing automated LVD instruments; main technology concerns about LVD today; and where vendors need to improve/enhance their automated LVD systems today.

The main questionnaire consisted of 29 multi-choice questions and 1 open-ended question. In addition, there were 6 questions related solely to survey demographics.

The survey collected 77 validated responses, of these 68% provided comprehensive input.

Survey responses were geographically split: 60% North America; 32% Europe; 7% Asia (excluding Japan & China); and 1% Japan.

Respondents came from 35 University/Research Institute/Government Labs/Not-for-Profit; 17 Pharmaceutical; 7 Biotech; 5 Contract Research Organisation; 5 Other; 4 Agrochemical/Agri-Biotech Company; 3 Medical School/ Hospital/Clinic; and 1 Diagnostics.

Most survey respondents had a senior job role or position which was in descending order: 22 research scientists; 11 senior scientists/researchers; 9 lab managers; 6 section/group leaders; 6 principal investigators; 5 post-docs; 4 professors/assistant professors; 4 others; 3 department heads; 2 lab technicians; 2 directors; 1 vice president; 1 compound store manager; and 1 graduate/PhD student.

Survey results were expressed as an average of all survey respondents. In addition, where appropriate the data was fully reanalyzed after sub-division into the following 5 survey groups: 1) Expert User 2); Moderately Aware; 3) Bioassays, Biotesting & Drug Screening; 4) Industry; and 5) University Research.

The main group activity of the majority of respondents was bioassays, biotesting & drug screening.

The majority of respondents were expert users (i.e. very familiar with most aspects of liquid handling, well equipped with all the latest automated liquid handing tools).

The majority of respondents were using LVD today.

The LVD system/device that most respondents have access to and use today was the Labcyte Echo.

The preferred approach to LVD was equally shared between acoustic droplet ejection and no preferred approach.

The LVD range most frequently used today was 0.5µL to 100nL.

The minimum droplet size most wanted by respondents for their intended LVD application was between 5nL and 2.5nL.

The dynamic dispensing range most want to access in the same LVD system was 3 logs (e.g. 10µL to 10nL).

Most thought it was highly desirable to have a very wide dynamic range (i.e. at least 4 logs) in a LVD.

The preferred number of dispensing channels in a LVD was 1-channel or 1 head (with multiple nozzles) addressing 1 well.

The flexibility required in dispensing channels was interchangeable head(s) and variable configurations.

The 384-well plate was the receptacle used most frequently with a LVD.

Treated polystyrene was the surface material/substrate most frequently used when LV dispensing.

An aqueous solution was the fluid type most frequently used with a LVD.

Most thought it was nice to have an aspirate function able to remove liquid from individual microtubes or 96, 384 and 1536 microplate wells in a LVD.

Most thought it was highly desirable to avoid disposable tips and washing in an LVD workflow.

The median acceptable dead volume for an automated LVD system was 2.5µL to 5µL.

The median acceptable dead volume in a source plate used in automated LVD was 2.5µL to 5µL.

Most thought it was highly desirable to automate the feed of labware to enable an automated LVD workflow.

The preferred approach to integrating an automated LVD system was to use the dispensers as currently provided by vendor.

The additional functionality that most needs to be integrated with an LVD to create a useful automated system was a plate sealer.

The walk-away plate stacker/hotel capacity required in an automated LVD system was 10-25 plates.

Non-contact dispensing was the LVD technology most needed for respondents' application(s).

The broad application area of LVD of greatest interest to respondents was miniaturized bioassays.

The specific application area of LVD of highest priority interest to respondents was dose-response - creation of drug dilution series from concentrate for use in a bioassay.

High cost of entry was ranked the biggest limitation to adopting acoustic droplet ejection technology.

The median probability of purchasing a new LVD system in the near future (2016-2018) was moderate (25-75%).

Accuracy and precision were ranked the most important features to consider when purchasing a new LVD.

The broad category of LVD that respondents were most interested in purchasing in the near future (2016-2018) was a non-contact dispenser (with nL range).

The specific LVD instrument that respondents find most appealing from a purchasing perspective in the near future was the Labcyte Echo.

The median annual budget for LVD instruments was $50K-$100K last year (2015).

A bottom-up model was developed to estimate the market for automated LVD instruments using respondent data on their budgets derived from this survey. The LVD instruments market was estimated to be around $50M in 2015. CAGR estimates and segmentation are given in the full report.

Accuracy and precision was ranked the main limitation of LVD today.

A minority of respondents thought there were areas where vendors need to improve/enhance their automated LVD offerings today and provided feedback on the aspects in need of vendor attention.

The full report provides the data, details of the breakdown of the responses for each question, its segmentation and the estimates for the future (2018). It also highlights some interesting differences between the survey groups.

Table of Contents

  • Executive Summary
  • Table Of Contents
  • Survey Methodology
  • Organisation & Response Of Survey Participants
  • Respondent's Company Or Organisational Origin
  • Respondent's Geographic Origin
  • Respondent's Job Role
  • Survey Respondent's Main Group Activity
  • Liquid Handling Expertise & Access To Dispensing Equipment
  • Respondents Currently Using LVD Today
  • LVD Systems/Devices Respondents Have Access To & Use Today (1)
  • LVD Systems/Devices Respondents Have Access To & Use Today (2)
  • Preferred Technology Approach To LVD
  • LVD Ranges Used
  • Summary Of Survey Findings (1)
  • Minimum Droplet Size Required For LVD Application
  • Dynamic Dispensing Range Wanted In The Same Automated LVD System
  • Importance Of A Very Wide Dynamic Dispensing Range In A LVD System
  • Preferred Number Of Dispensing Channels In A LVD
  • Flexibility Required In Dispensing Heads Or Manifolds In A LVD
  • Receptacle To Be Used Most Frequently With A LVD
  • Surface Materials/Substrates To Be Used Most Frequently When LV Dispensing
  • Fluid Types To Be Used Most Frequently With A LVD
  • Importance Of An Aspirate Function In A LVD
  • Importance In LVD Workflow To Avoid Disposable Tips & Washing
  • Acceptable Dead Volume For An Automated LVD System
  • Acceptable Dead Volume For A Source Plate Used In A LVD System
  • Importance Of Automating The Feed Of Labware In Enabling An Automated LVD Workflow
  • Preferred Method Of Integrating An Automated LVD System
  • Additional Functionality Needed In An Automated LVD
  • Walk-Away Plate Stacker/Hotel Capacity Required In An Automated LVD System
  • Summary Of Survey Findings (2)
  • LVD Technology Most Needed For Respondent's Applications
  • Broad Application Areas Of LVD Of Interest To Respondents
  • Specific Application Area Of LVD Of High Interest To Respondents (1)
  • Specific Application Area Of LVD Of High Interest To Respondents (1)
  • Main Limitations To Adopting Acoustic Droplet Ejection Technology
  • Probability Of Purchasing A New LVD System On The Near Future
  • Most Important Features When Considering Purchasing An LVD System (1)
  • Most Important Features When Considering Purchasing An LVD System (1)
  • Broad Category Of LVD Of Most Interest To Purchase In The Near Future
  • LVD Systems Respondents Are Most Interested In Purchasing In The Near Future (1)
  • LVD Systems Respondents Are Most Interested In Purchasing In The Near Future (2)
  • Annual Budgets For Purchasing LVD Instruments
  • Market Estimate For Automated LVD Instruments
  • Main Limitations Of LVD Today
  • Areas Where Vendors Need To Improve Their Automated LVD Offering Today
  • Summary Of Survey Findings (3)
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