Next-Generation Glycemic Control Therapeutics
|出版商||Greystone Research Associates||商品編碼||337816|
As the number of patients diagnosed with diabetes continues to climb worldwide, drug developers and researchers are attempting for find more effective ways to control glucose levels, particularly for Type 2 diabetics. These efforts have led to a growing list of GLP-1 agonists and DPP-4 inhibitors that have been approved or are in late stage clinical development. New medicines based on novel therapeutic moieties and potentially unique benefits are attracting attention and research investment. The result is an evolving therapeutic landscape that is providing clinicians and patients with new ways to manage their diabetes. For market participants, product positioning and prescriber training will become increasingly important as competitive threats remain fluid.
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A longer life span is expected to translate to a growing number of patients diagnosed with chronic conditions. To counteract the financial and medical infrastructure implications of this trend, pressure from the public sector and managed care organizations will place a premium on therapeutic self-administration, an expectation that is creating an increased interest in routes of administration that are patient-friendly and cost-effective. Pharma company decision makers have come to the realization that for many products, success no longer only depends on the medication itself but also on achieving a consumer-compatible form of packaging and application.
The market for glycemic control continues to grow globally at rates that are alarming to public health officials. Over the past decade, prevalence of diabetes among adults has increased by 33 percent. In the United States, approximately 6 percent of the population (i.e., 16 million people) has diabetes and it is the fourth-leading cause of death by disease. Among Americans in their thirties, diabetes has increased by 70 percent in the past 10 years. Each year, approximately 798,000 people are diagnosed with diabetes. However, one-third of the people afflicted are currently undiagnosed.
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