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市場調查報告書
全球分子細胞基因學市場
Molecular Cytogenetics
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全球分子細胞基因學市場 是由出版商Global Industry Analysts, Inc.在2011年08月所出版的。
這份英文市場調查報告書包含Pages: 239 價格從美金4800起跳。
本報告書為全球分子細胞基因學市場的相關調査分析、分子細胞基因學以及FISH技術概要、產品上市動向、、全球主要各地區的動向、以及相關企業簡介等整理，概述如下。
第1章 導論、調査方法、產品定義
第2章 業界概要
- 分子生物學技術的進歩擴大了細胞基因學的範圍
- FISH：生物醫學研究的主要技術
- 讓造成癌症的基因子等級的疾病管理進歩的分子細胞基因學
- 大幅促進市場成長的陣列技術
- 從FISH轉為陣列技術
- 針對染色體異常的臨床診斷的第一次檢査而抬頭的陣列CGH
- 市場前景
- 分子細胞基因學在臨床病理學檢査的普及率提升
- 最新AP LIS與分子細胞基因學檢査都需要改良
- 對研究到開發的生物醫藥品之注目影響了變化中的微陣列技術
- 遙遠的將來、對於微陣列技術的次世代定序
第3章 技術概要
- 細胞基因學概要
- 分子生物學知基本的用語與定義
- 染色體
- 基因子
- 基因子型
- 表現型
- 單體型分析
- 染色體分析
- 核型
- 切口
- 探針
- 報告者分子
- 複製數
- 複製數變化
- 染色體異常概要
- 分子細胞基因學：定義與範圍
- 分子細胞基因學之應用
- 分子細胞基因學技術概要
- 螢光in situ雜交反應（FISH）是甚麼
- 比傳統技術來說，FISH會更好嗎
- FISH：程序
- 探針種類與應用
- FISH應用
- FISH種類 其他
第4章 近年業界活動
第5章 產品上市
第6章 主要企業
- Abbott Molecular Inc.
- Affymetrix, Inc.
- Applied Spectral Imaging
- BI Biological Industries
- Bluegnome, ltd.
- ChromTrax
- CytoTest, Inc.
- Cytognomix, Inc.
- Illumina, Inc.
- Inter Medico
- Kreatech Diagnostics
- Life Technologies Corporation
- Oxford Gene Technology
- PerkinElmer, Inc.
- Roche NimbleGen, Inc.
- SciGene Corporation
第7章 世界市場前景
第8章 北美
第9章 歐洲
第10章 其他地區
企業簡介：24家
Abstract
This report analyzes the worldwide markets for Molecular Cytogenetics: in US$ Million by the following technologies: Fluorescence In Sit Hybridization (FISH), and Array-based Technology. The report provides separate comprehensive analytics for the North America, Europe, and Rest of World. Annual estimates and forecasts are provided for the period 2009 through 2017. Also, a six-year historic analysis is provided for these markets. The report profiles 24 companies including many key and niche players such as Abbott Molecular Inc., Affymetrix, Inc., Applied Spectral Imaging, BI Biological Industries, Bluegnome, ltd., ChromTrax, CytoTest, Inc., Cytognomix, Inc., lllumina, Inc., Inter Medico, Kreatich Diagnostics, Life Technologies Corporation, Oxford Gene Technology, PerkinElmer, Inc., Roche NimbleGen, Inc., and SciGene Corporation. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.
Table of Contents
1. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
- Study Reliability and Reporting Limitations
- Disclaimers
- Data Interpretation & Reporting Level
- Quantitative Techniques & Analytics
- Product Definitions and Scope of Study
- Definitions
- Fluorescence In Situ Hybridization
- Select FISH Procedures in Use
- 3D-FISH
- Cellular Compartment Analysis of Temporal Activity
- Combined Binary Ratio-FISH
- Cryo-FISH
- Immuno-FISH
- Quantum Dot-Conjugates-FISH
- Array-based Technology
- Microarrays in Comparative Genomic Hybridization
2. INDUSTRY OVERVIEW
- Advances in Molecular Biology Techniques Broaden the Scope of Cytogenetics
- FISH: The Leading Technology in Biomedical Research
- Molecular Cytogenetics to Advance Gene-Level Disease Management in
Oncology
- Diverse Applications of FISH Technology in Oncology
- Array Based Technologies To Drive Significant Market Growth
- Transition from FISH to Array Based Technologies: A Major Trend
- Array-based CGH to Emerge as First Line Test for Clinical Diagnosis of
Chromosomal Anomalies
- Market Outlook
- Molecular Cytogenetics Find Increasing Penetration in Clinical
Pathological Testing
- Enhanced AP LIS a Must to Keep Pace with Advancing Molecular
Cytogenetic Testing
- Impact of Shifting Focus of Biopharmaceuticals from Research to
Development on Microarray Technology
- Next-Gen Sequencing to Challenge Microarray Technology in the Distant
Future
3. TECHNOLOGY OVERVIEW
- A Preface to Cytogenetics
- Basic Terms and Definitions in Molecular Biology
- DNA and RNA
- RNA (Ribose nucleic acid)
- Chromosomes
- Gene
- Genotype
- Phenotype
- Haplotype
- Karyotyping
- Karyotype
- Nick
- Probe
- Reporter Molecule
- Copy Number
- Copy Number Variation
- Analysis of Copy Numbers Variations
- Chromosomal Abnormalities in Human Beings
- An Overview of Select Chromosomal Anomalies
- Insertions
- Deletions
- Duplication
- Rearrangement
- Select Human Diseases/Abnormalities Arising due to Translocations
- Molecular Cytogenetics: Definition and Scope
- Application of Molecular Cytogenetics
- Insight into Molecular Cytogenetics Techniques
- Fluorescence In Situ Hybridization (FISH)
- What is In Situ Hybridization?
- How is FISH Better than Conventional Techniques?
- Fluorescence In Situ Hybridization: The Process
- Probe Types and Application
- Types of Probes
- Common Methods of Probe Preparation
- Nick Translation and Polymerase Chain Reaction (PCR)
- Applications of FISH
- Types of FISH
- 3D-FISH
- ACM-FISH or Multicolor FISH
- ArmFISH
- Catalyzed Reporter Deposition-FISH
- Cellular Compartment Analysis of Temporal Activity
- Cytochalasin-B -FISH
- Combined Binary Ratio-FISH
- Chromosome Orientation And Direction FISH
- Combinatorial Oligonucleotide -FISH
- Comet-FISH
- Cryo-FISH
- Double-Fusion -FISH
- DNA Breakage Detection -FISH
- e-FISH
- Fiber-FISH
- Flow-FISH
- Fusion-Signal FISH
- Halo-FISH
- Harlequin-FISH
- Immuno-FISH
- Locked Nucleic Acids-FISH
- M-FISH
- Multilocus-FISH
- Premature Chromosome Condensation-FISH
- Peptide Nucleic Acids-FISH
- Novel FISH Technology to Detect Plague Bacillus
- Quantitative-FISH
- Quantum Dot-Conjugates-FISH
- Rainbow-FISH
- Reverse-FISH
- Recognition of Individual Genes-FISH
- Expression-FISH
- RxFISH
- Split-Signal FISH
- Telomere-FISH/ Tissue-FISH/ Tyramide-FISH (T-FISH)
- Zoo-FISH
- Spectral Karyotyping (SKY) Technique
- Mouse FISH - a New Development
- Comparative Genomic Hybridization
- CGH: The Process
- CGH: Applications In Clinical Cytogenetics
- Benefits of CGH Analysis in Clinical Genetics
- Limitations of CGH
- Advent of Microarray Technology
- What are Microarrays?
- Microarrays in Gene Expression Analysis
- Microarrays in Comparative Genomic Hybridization
- Principle Underlying aCGH
- Low Resolution and High Resolution aCGH
- ACGH: The Process
- aCGH: Potential Uses and Limitations
- Potential Advantages of aCGH could be summarized as below
- Limitations of aCGH
- Analytical and Post-analytical Limitations
- Interpretation of Results
- Applications of aCGH
- A Review of Molecular Biology Techniques in Cytogenetics
4. RECENT INDUSTRY ACTIVITY
- Agilent and Kreatech Enter into New License and Supply Deal
- Clarient to Commercialize CombiMatrix' s Genomic Profile Tests for Cancer
- Kreatech Inks License Agreement with Veridex to Use Repeat-Free™
Technology
- PerkinElmer to Acquire Signature Genomic Laboratories
- Illumina to Submit Micro-Array based iscan Technology to the US FDA
through Pre-IDE Process
- Invitrogen Announces Merger with Applied Biosystems
- LabCorp to Use GeneChip Technology of Affymetrix
- Dako Denmark Receives FDA Approval for TOP2A FISH pharmDx Device
- Abbott Partners with Roche, OSI and Genentech
5. PRODUCT LAUNCHES
- BlueGnome Rolls Out CytoChip Cancer
- PerkinElmer Introduces Prenatal BACs-on-Beads™ Assay in Europe
- Agilent Introduces New SNP Probes for SurePrint G3 Human CGH Platform
- Affymetrix Launches Two Novel Microarrays for Cytogenetics
- Roche Applied Science Introduces NimbleGen CGX
- Gastrocor Launches GastroFISH
- Roche NimbleGen Introduces New Probe Arrays
- Ambry Genetics Launches Whole-Genome Chromosomal Microarray Analysis
- London Genetics Introduces New Molecular Cytogenetics Service
- OGT Introduces Genomic DNA Labeling Kit
- Oxford Gene Technology Introduces New Sample Tracking DNA Labeling Kits
- BlueGnome Introduces 24sure™
6. FOCUS ON SELECT PLAYERS
- Abbott Molecular Inc. (US)
- Affymetrix, Inc. (US)
- Applied Spectral Imaging (US)
- BI Biological Industries (Israel)
- Bluegnome, ltd. (UK)
- ChromTrax (US)
- CytoTest, Inc. (UK)
- Cytognomix, Inc. (Canada)
- Illumina, Inc. (US)
- Inter Medico (Canada)
- Kreatech Diagnostics (The Netherlands)
- Life Technologies Corporation (US)
- Oxford Gene Technology (UK)
- PerkinElmer, Inc. (US)
- Roche NimbleGen, Inc. (US)
- SciGene Corporation (US)
7. GLOBAL MARKET PERSPECTIVE
- Table 1: World Recent Past Current & Future Analysis for Molecular
Cytogenetics Technologies by Geographic Region - North America, Europe, and
Rest of World Independently Analyzed with Annual Sales Figures in US$ Thousand
for Years 2009 through 2017 (includes corresponding Graph/Chart)
- Table 2: World Historic Review for Molecular Cytogenetics Technologies
by Geographic Region - North America, Europe, and Rest of World Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years 2003 through 2008
(includes corresponding Graph/Chart)
- Table 3: World 15-Year Perspective for Molecular Cytogenetics
Technologies by Geographic Region - Percentage Breakdown of Dollar Sales for
North America, Europe, and Rest of World for Years 2003, 2010 & 2017
(includes corresponding Graph/Chart)
- By Technology
- Table 4: World Recent Past Current & Future Analysis for
Fluorescence In Situ Hybridization by Geographic Region - North America,
Europe, and Rest of World Independently Analyzed with Annual Sales Figures in
US$ Thousand for Years 2009 through 2017 (includes corresponding Graph/Chart)
- Table 5: World Historic Review for Fluorescence In Situ Hybridization
by Geographic Region - North America, Europe, and Rest of World Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years 2003 through 2008
(includes corresponding Graph/Chart)
- Table 6: World 15-Year Perspective for Fluorescence In Situ
Hybridization by Geographic Region - Percentage Breakdown of Dollar Sales for
North America, Europe, and Rest of World for Years 2003, 2010 & 2017 2010
& 2017 (includes corresponding Graph/Chart)
- Table 7: World Recent Past Current & Future Analysis for
Array-Based Technology by Geographic Region - North America, Europe, and Rest
of World Independently Analyzed with Annual Sales Figures in US$ Thousand for
Years 2009 through 2017 (includes corresponding Graph/Chart)
- Table 8: World Historic Review for Array-Based Technology by Geographic
Region - North America, Europe, and Rest of World Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2003 through 2008 (includes
corresponding Graph/Chart)
- Table 9: World 15-Year Perspective for Array-Based Technology by
Geographic Region - Percentage Breakdown of Dollar Sales for North America,
Europe, and Rest of World for Years 2003, 2010 & 2017 (includes
corresponding Graph/Chart)
8. NORTH AMERICA
- A. Market Analysis
- Market Trends
- aCGH to Predominate the Technological Front in Molecular Cytogenetics
in Future
- Revised ACMG Guidelines to Accelerate Use of aCGH Over FISH in the US
- The Clinical Sector: A Potential Market Opportunity for Array-based
Technologies
- FISH in the Cancer Diagnostics Scenario in the US
- Market Restraints
- Immunohistochemical (IHC) Tests: The Most Recommended Diagnostic Test
for Cancers
- Factors Limiting the Growth of FISH Technology in Cancer Diagnostics
- FISH in Diagnosis of Bladder Carcinoma
- FISH in Breast Cancer Diagnosis
- Table 10: Overview of Prices of Testing Products based Various
Technologies
- Table 11: Medicare Reimbursement Provided for HER-2/Neu
- Strategic Corporate Developments
- Product Launches
- Focus on Select Major Players
- Abbott Molecular Inc.
- Affymetrix, Inc.
- Applied Spectral Imaging
- ChromTrax
- Cytognomix, Inc.
- Illumina, Inc.
- Inter Medico
- Life Technologies Corporation
- PerkinElmer, Inc.
- Roche NimbleGen, Inc.
- SciGene Corporation
- B. Market Analytics
- Table 12: North American Recent Past Current & Future Analysis
for Molecular Cytogenetics by Technology (Fluorescence In Situ Hybridization
and Array-based Technology) Independently Analyzed with Annual Sales Figures
in US$ Thousand for Years 2009 through 2017 (includes corresponding
Graph/Chart)
- Table 13: North American Historic Review for Molecular Cytogenetics
by Technology Type Fluorescence In Situ Hybridization and Array-based
Technology Independently Analyzed with Annual Sales Figures in US$ Thousand
for Years 2003 through 2008 (includes corresponding Graph/Chart)
- Table 14: North American 15-Year Perspective for Molecular
Cytogenetics Market by Technology - Percentage Breakdown of Dollar Sales for
Fluorescence In Situ Hybridization and Array-based Technology for Years
2003, 2010 & 2017 (includes corresponding Graph/Chart)
9. EUROPE
- A. Market Analysis
- B. Market Analytics
- Table 15: European Recent Past Current & Future Analysis for
Molecular Cytogenetics Market by Region- France, Germany, Italy, UK, and
Rest of Europe Independently Analyzed with Annual Sales Figures in US$
Thousand for Years 2009 through 2017 (includes corresponding Graph/Chart)
- Table 16: European Historic Review for Molecular Cytogenetics Market
by Region- France, Germany, Italy, UK, and Rest of Europe Independently
Analyzed with Annual Sales Figures in US$ Thousand for Years 2003 through
2008 (includes corresponding Graph/Chart)
- Table 17: European 15-Year Perspective for Molecular Cytogenetics
Market by Technology - Percentage Breakdown of Dollar Sales for France,
Germany, Italy, UK, and Rest of Europe for Years 2003, 2010 & 2017
(includes corresponding Graph/Chart)
9a. FRANCE
- Market Analysis
- Table 18: French Recent Past Current & Future Analysis for
Molecular Cytogenetics Market by Technology (Fluorescent In Situ
Hybridization and Array-based Technology) Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2009 through 2017 (includes
corresponding Graph/Chart)
- Table 19: French Historic Review for Molecular Cytogenetics Market
by Technology (Fluorescent In Situ Hybridization and Array-based Technology)
Independently Analyzed with Annual Sales Figures in US$ Thousand for Years
2003 through 2008 (includes corresponding Graph/Chart)
- Table 20: French 15-Year Perspective for Molecular Cytogenetics
Market by Technology - Percentage Breakdown of Dollar Sales for Fluorescent
In Situ Hybridization and Array-based Technology for Years 2003, 2010 &
2017 (includes corresponding Graph/Chart)
9b. GERMANY
- Market Analysis
- Table 21: German Recent Past Current & Future Analysis for
Molecular Cytogenetics Market by Technology (Fluorescent In Situ
Hybridization and Array-based Technology) Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2009 through 2017 (includes
corresponding Graph/Chart)
- Table 22: German Historic Review for Molecular Cytogenetics Market
by Technology (Fluorescent In Situ Hybridization and Array-based Technology)
Independently Analyzed with Annual Sales Figures in US$ Thousand for Years
2003 through 2008 (includes corresponding Graph/Chart)
- Table 23: German 15-Year Perspective for Molecular Cytogenetics
Market by Technology - Percentage Breakdown of Dollar Sales for Fluorescent
In Situ Hybridization and Array-based Technology for Years 2003, 2010 &
2017 (includes corresponding Graph/Chart)
9c. ITALY
- Market Analysis
- Table 24: Italian Recent Past Current & Future Analysis for
Molecular Cytogenetics Market by Technology (Fluorescent In Situ
Hybridization and Array-based Technology) Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2009 through 2017 (includes
corresponding Graph/Chart)
- Table 25: Italian Historic Review for Molecular Cytogenetics Market
by Technology (Fluorescent In Situ Hybridization and Array-based Technology)
Independently Analyzed with Annual Sales Figures in US$ Thousand for Years
2003 through 2008 (includes corresponding Graph/Chart)
- Table 26: Italian 15-Year Perspective for Molecular Cytogenetics
Market by Technology - Percentage Breakdown of Dollar Sales for Fluorescent
In Situ Hybridization and Array-based Technology for Years 2003, 2010 &
2017 (includes corresponding Graph/Chart)
9d. THE UNITED KINGDOM
- A. Market Analysis
- Product Launches
- Focus on Select Major Players
- BlueGnome, Ltd.
- CytoTest, Inc.
- Oxford Gene Technology
- B. Market Analytics
- Table 27: The United Kingdom Recent Past Current & Future
Analysis for Molecular Cytogenetics Market by Technology (Fluorescent In
Situ Hybridization and Array-based Technology) Independently Analyzed with
Annual Sales Figures in US$ Thousand for Years 2009 through 2017 (includes
corresponding Graph/Chart)
- Table 28: The United Kingdom Historic Review for Molecular
Cytogenetics Market by Technology (Fluorescent In Situ Hybridization and
Array-based Technology) Independently Analyzed with Annual Sales Figures in
US$ Thousand for Years 2003 through 2008 (includes corresponding
Graph/Chart)
- Table 29: The United Kingdom 15-Year Perspective for Molecular
Cytogenetics Market by Technology - Percentage Breakdown of Dollar Sales for
Fluorescent In Situ Hybridization and Array-based Technology for Years 2003,
2010 & 2017 (includes corresponding Graph/Chart)
9e. REST OF EUROPE
- A. Market Analysis
- Strategic Corporate Developments
- Focus on Select Major Players
- Kreatech Diagnostics
- Roche Diagnostics, Corp.
- B. Market Analytics
- Table 30: Rest of European Recent Past Current & Future Analysis
for Molecular Cytogenetics Market by Technology (Fluorescent In Situ
Hybridization and Array-based Technology) Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2009 through 2017 (includes
corresponding Graph/Chart)
- Table 31: Rest of European Historic Review for Molecular
Cytogenetics Market by Technology (Fluorescent In Situ Hybridization and
Array-based Technology) Independently Analyzed with Annual Sales Figures in
US$ Thousand for Years 2003 through 2008 (includes corresponding
Graph/Chart)
- Table 32: Rest of European 15-Year Perspective for Molecular
Cytogenetics Market by Technology - Percentage Breakdown of Dollar Sales for
Fluorescent In Situ Hybridization and Array-based Technology for Years 2003,
2010 & 2017 (includes corresponding Graph/Chart)
10. REST OF WORLD
- A. Market Analysis
- China: A Potential Market for FISH Technology in Clinical Diagnostics
- Table 33: Penetration of FISH in Chinese Hospitals (2008-2012)
(includes corresponding Graph/Chart)
- Table 34: Penetration of FISH in Tier-1 Chinese Hospitals
(2008-2012) (includes corresponding Graph/Chart)
- Table 35: Penetration of FISH in Tier-2 Chinese Hospitals
(2008-2012)
- Table 36: Overview of Select FISH Products Offered by Abbott and
CMED: A Comparison (in RMB) (includes corresponding Graph/Chart)
- An Insight into the Indian Microarray Market
- Focus on Select Major Player
- BI Biological Industries
- B. Market Analytics
- Table 37: Rest of World Recent Past Current & Future Analysis
for Molecular Cytogenetics Market by Technology (Fluorescence In Situ
Hybridization and Array-based Technology) Independently Analyzed with Annual
Sales Figures in US$ Thousand for Years 2009 through 2017 (includes
corresponding Graph/Chart)
- Table 38: Rest of World Historic Review for Molecular Cytogenetics
Market by Technology (Fluorescence In Situ Hybridization and Array- based
Technology) Independently Analyzed with Annual Sales Figures in US$ Thousand
for Years 2003 through 2008 (includes corresponding Graph/Chart)
- Table 39: Rest of World 15-Year Perspective for Molecular
Cytogenetics Market by Technology - Percentage Breakdown of Dollar Sales for
Fluorescent In Situ Hybridization and Array-based Technology for Years 2003,
2010 & 2017 (includes corresponding Graph/Chart)
COMPETITIVE LANDSCAPE
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